kynurenine and allopurinol

kynurenine has been researched along with allopurinol in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kirk, L; Møller, SE1
Green, AR; Joseph, MH; Woods, HF2
Curzon, G; Green, AR1
Badawy, AA; Evans, M1
Becking, GC; Johnson, WJ1
Adachi, H; Motomatsu, K1
Katsuki, H; Nishiyama, N; Okuda, S; Saito, H1
Bredesen, DE; Chen, RW; Chuang, DM; Leeds, P; Leng, Y; Wei, H; Wei, W1
Fujigaki, S; Fujii, H; Maekawa, N; Morita, T; Noma, A; Saito, K; Seishima, M; Takemura, M; Takeuchi, S; Wada, H1
Connor, TJ; Fagan, EM; Gibney, SM; Harkin, A; O'Byrne, J; Waldron, AM1
Badawy, AA1

Reviews

1 review(s) available for kynurenine and allopurinol

ArticleYear
Hypothesis: Metabolic targeting of 5-aminolevulinate synthase by tryptophan and inhibitors of heme utilisation by tryptophan 2,3-dioxygenase as potential therapies of acute hepatic porphyrias.
    Medical hypotheses, 2019, Volume: 131

    Topics: 5-Aminolevulinate Synthetase; Allopurinol; Animals; Enzyme Induction; Enzyme Inhibitors; Fasting; Feedback, Physiological; Gene Silencing; Glucose; Guinea Pigs; Heme; Humans; Kynurenine; Liver; Models, Biological; Molecular Targeted Therapy; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Porphyrias, Hepatic; Rodentia; Species Specificity; Tryptophan; Tryptophan Oxygenase

2019

Other Studies

11 other study(ies) available for kynurenine and allopurinol

ArticleYear
The effect of allopurinol on the kynurenine formation in humans following a tryptophan load.
    Acta vitaminologica et enzymologica, 1978, Volume: 32, Issue:5-6

    Topics: Allopurinol; Bipolar Disorder; Humans; Kynurenine; Tryptophan

1978
Proceedings: Tryptophan metabolism by the isolated perfused rat liver.
    British journal of pharmacology, 1975, Volume: 55, Issue:2

    Topics: Allopurinol; Hydrocortisone; Kynurenine; Liver; Perfusion; Tryptophan

1975
Tryptophan metabolism in the isolated perfused liver of the rat: effects of tryptophan concentration, hydrocortisone and allopurinol on tryptophan pyrrolase activity and kynurenine formation.
    British journal of pharmacology, 1976, Volume: 57, Issue:1

    Topics: Age Factors; Allopurinol; Animals; Cycloheximide; Hydrocortisone; In Vitro Techniques; Kynurenine; Liver; Male; Rats; Time Factors; Tryptophan; Tryptophan Oxygenase

1976
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates

1970
Guinea-pig liver tryptophan pyrrolase. Absence of detectable apoenzyme activity and of hormonal induction by cortisol and possible regulation by tryptophan.
    The Biochemical journal, 1974, Volume: 138, Issue:3

    Topics: Aging; Allopurinol; Animals; Apoproteins; Cycloheximide; Dactinomycin; Enzyme Induction; Enzyme Precursors; Guinea Pigs; Hydrocortisone; Injections, Intraperitoneal; Kynurenine; Liver; Male; Rats; Tryptophan; Tryptophan Oxygenase

1974
The inhibition of tryptophan pyrrolase by allopurinol, an inhibitor of xanthine oxidase.
    Canadian journal of biochemistry, 1967, Volume: 45, Issue:11

    Topics: Allopurinol; Animals; Female; Kinetics; Kynurenine; Liver; Rats; Tryptophan; Tryptophan Oxygenase; Xanthine Oxidase

1967
[The possibility of superoxide-production during hemorrhagic shock observing the effect of allopurinol on the level of serum lipidperoxide and kynurenine (author's transl)].
    Masui. The Japanese journal of anesthesiology, 1982, Volume: 31, Issue:2

    Topics: Allopurinol; Animals; Kynurenine; Lipid Peroxides; Male; Oxygen; Rabbits; Shock, Hemorrhagic; Superoxides; Xanthine Oxidase

1982
Hydrogen peroxide-mediated neuronal cell death induced by an endogenous neurotoxin, 3-hydroxykynurenine.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Oct-29, Volume: 93, Issue:22

    Topics: Animals; Catalase; Cell Death; Cells, Cultured; Corpus Striatum; Deferoxamine; Hydrogen Peroxide; Kynurenine; NADPH Dehydrogenase; Neurons; Peroxides; Rats; Rats, Wistar; Superoxide Dismutase; Xanthine Oxidase

1996
Neuronal apoptosis induced by pharmacological concentrations of 3-hydroxykynurenine: characterization and protection by dantrolene and Bcl-2 overexpression.
    Journal of neurochemistry, 2000, Volume: 75, Issue:1

    Topics: Animals; Apoptosis; Cerebellum; Chromatin; Dantrolene; DNA Fragmentation; Drug Synergism; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression; Iron Chelating Agents; Kynurenine; Metalloporphyrins; Neurons; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Xanthine Oxidase

2000
3-Hydroxyanthranilic acid, an L-tryptophan metabolite, induces apoptosis in monocyte-derived cells stimulated by interferon-gamma.
    Annals of clinical biochemistry, 2001, Volume: 38, Issue:Pt 3

    Topics: 3-Hydroxyanthranilic Acid; Antioxidants; Apoptosis; Cell Line; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Interferon-gamma; Kynurenine; Monocytes; Spectrophotometry; Tryptophan; Tumor Cells, Cultured; U937 Cells; Xanthine Oxidase

2001
Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:6

    Topics: Allopurinol; Animals; Antidepressive Agents; Cerebral Cortex; Chronic Disease; Corticosterone; Depressive Disorder; Disease Models, Animal; Enzyme Inhibitors; Kynurenine; Liver; Male; Neuropsychological Tests; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Stress, Psychological; Tryptophan; Tryptophan Oxygenase; Weight Gain

2014