kynurenic acid has been researched along with zaprinast in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Deng, H; Fang, Y; He, M; Hu, H; Hu, J | 1 |
| Funke, M; Müller, CE; Schiedel, AC; Thimm, D | 1 |
| Funke, M; Meyer, A; Müller, CE; Thimm, D | 1 |
| Fang, Y; Hou, T; Li, J; Liang, X; Qu, L; Shi, L; Wang, J; Wang, P; Wei, L; Zhang, X; Zhao, Y | 1 |
| Cheng, J; Hou, T; Li, J; Liang, X; Wang, J; Wang, Z; Wei, L; Xiang, K; Zhang, X; Zhao, Y; Zhou, H | 1 |
| Guo, J; Ikeda, SR; Puhl, HL; Williams, DJ | 1 |
| Oka, S; Ota, R; Shima, M; Sugiura, T; Yamashita, A | 1 |
| de Lalla, C; Fallarini, S; Lombardi, G; Magliulo, L; Paoletti, T | 1 |
| Alvarez-Curto, E; Campbell, K; Canals, M; de Munnik, S; Jenkins, L; Milligan, G; Schlyer, S | 1 |
| Carlà, V; Cavone, L; Cosi, C; Cozzi, A; Mannaioni, G; Maratea, D; Moroni, F; Sili, M | 1 |
| Laurino, A; Mannaioni, G; Masi, A; Moroni, F; Resta, F; Sili, M | 1 |
| Ciapała, K; Mika, J; Rojewska, E | 1 |
13 other study(ies) available for kynurenic acid and zaprinast
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Thieno[3,2-b]thiophene-2-carboxylic acid derivatives as GPR35 agonists.
Topics: Anti-Inflammatory Agents; Arrestins; beta-Arrestins; Biological Assay; Dose-Response Relationship, Drug; HT29 Cells; Humans; Ligands; Protein Transport; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship; Thiophenes | 2012 |
8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35.
Topics: Animals; Carboxylic Acids; Chemical Phenomena; Drug Stability; Humans; Hydrolysis; Ligands; Mice; Rats; Receptors, G-Protein-Coupled; Species Specificity; Structure-Activity Relationship; Substrate Specificity | 2013 |
6-Bromo-8-(4-[(3)H]methoxybenzamido)-4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35.
Topics: Carboxylic Acids; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Radioligand Assay; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 2013 |
Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists.
Topics: Benzopyrans; Carbon-13 Magnetic Resonance Spectroscopy; HT29 Cells; Humans; Mass Spectrometry; Proton Magnetic Resonance Spectroscopy; Receptors, G-Protein-Coupled | 2017 |
Structure-Activity Relationship Studies of Coumarin-like Diacid Derivatives as Human G Protein-Coupled Receptor-35 (hGPR35) Agonists and a Consequent New Design Principle.
Topics: Animals; Catalytic Domain; Cell Line, Tumor; CHO Cells; Coumarins; Cricetulus; Dicarboxylic Acids; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 2021 |
Inhibition of N-type calcium channels by activation of GPR35, an orphan receptor, heterologously expressed in rat sympathetic neurons.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, N-Type; DNA, Complementary; HeLa Cells; Humans; Kynurenic Acid; Male; Neurons; Pertussis Toxin; Protein Isoforms; Purinones; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Superior Cervical Ganglion | 2008 |
GPR35 is a novel lysophosphatidic acid receptor.
Topics: Adenosine; Calcium; Cannabinoid Receptor Agonists; Cell Line; Extracellular Signal-Regulated MAP Kinases; Humans; Kynurenic Acid; Ligands; Lysophospholipids; Purinones; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; rhoA GTP-Binding Protein | 2010 |
Expression of functional GPR35 in human iNKT cells.
Topics: Cell Membrane; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Interleukin-4; Kynurenic Acid; Natural Killer T-Cells; Pertussis Toxin; Purinones; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2.
Topics: Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Biological Assay; Cells, Cultured; Colon; Excitatory Amino Acid Antagonists; Ganglia, Spinal; GTP-Binding Protein alpha Subunits, G12-G13; Humans; Kynurenic Acid; Phosphodiesterase Inhibitors; Protein Binding; Protein Structure, Tertiary; Purinones; Rats; Receptors, G-Protein-Coupled; Transfection | 2011 |
G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast.
Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Gene Expression; Inflammation; Kynurenic Acid; Kynurenine; Male; Mice; Neuroglia; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Probenecid; Purinones; Receptors, G-Protein-Coupled; Spinal Cord; Tryptophan | 2011 |
Kynurenic acid and zaprinast induce analgesia by modulating HCN channels through GPR35 activation.
Topics: Analgesia; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Kynurenic Acid; Purinones; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2016 |
Kynurenic acid and zaprinast diminished CXCL17-evoked pain-related behaviour and enhanced morphine analgesia in a mouse neuropathic pain model.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Chemokines, CXC; Disease Models, Animal; Injections, Spinal; Kynurenic Acid; Male; Mice; Morphine; Pain Perception; Pain Threshold; Purinones; Receptors, G-Protein-Coupled; Sciatica; Spinal Cord | 2019 |