Compounds > kynurenic acid

kynurenic acid and pf-04859989

kynurenic acid has been researched along with pf-04859989 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Gritton, H; Johnson, DE; Koshy Cherian, A; Kozak, R; Sarter, M; Young, D1
Abbott, AL; Campbell, BM; Castner, SA; Chapin, DS; Dounay, A; Fonseca, K; Guanowsky, V; Hajos, M; Hoffmann, WE; Horner, W; Kiss, T; Kozak, R; McGinnis, D; Roberts, BM; Seymour, PA; Strick, CA; Williams, GV; Young, DA1
Campbell, BM; Chang, C; Dounay, A; Fonseca, KR; Gernhardt, SS; Horner, W; Li, C; Liras, J; Maurer, TS; Rong, H; Salafia, MA; Sawant-Basak, A; Strick, CA; Tuttle, JB; Verhoest, P; Welch, KA; Zawadzke, LE1
Bucci, DJ; Fukuwatari, T; Klausing, AD; Schwarcz, R1
Ardalan, N; Farshadfar, C; Hosseininezhadian Koushki, E; Noorbakhsh, A1

Other Studies

5 other study(ies) available for kynurenic acid and pf-04859989

ArticleYear
A systemically-available kynurenine aminotransferase II (KAT II) inhibitor restores nicotine-evoked glutamatergic activity in the cortex of rats.
    Neuropharmacology, 2014, Volume: 82

    Topics: Animals; Central Nervous System Agents; Enzyme Inhibitors; Glutamic Acid; Kynurenic Acid; Kynurenine; Male; Membrane Potentials; Microdialysis; Microelectrodes; Nicotine; Nicotinic Agonists; Potassium Chloride; Prefrontal Cortex; Pyrazoles; Rats, Sprague-Dawley; Rats, Wistar; Transaminases

2014
Reduction of brain kynurenic acid improves cognitive function.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Aug-06, Volume: 34, Issue:32

    Topics: Animals; Attention; Brain; Cognition; Enzyme Inhibitors; Evoked Potentials, Auditory; Female; Hippocampus; Humans; Kynurenic Acid; Macaca mulatta; Male; Maze Learning; Memory, Short-Term; Neurons; Pyrazoles; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Schizophrenia; Wakefulness

2014
Quantitative Translational Analysis of Brain Kynurenic Acid Modulation via Irreversible Kynurenine Aminotransferase II Inhibition.
    Molecular pharmacology, 2018, Volume: 94, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Female; Half-Life; Humans; Kynurenic Acid; Macaca fascicularis; Male; Pyrazoles; Rats; Tandem Mass Spectrometry; Transaminases

2018
Stress-induced impairment in fear discrimination is causally related to increased kynurenic acid formation in the prefrontal cortex.
    Psychopharmacology, 2020, Volume: 237, Issue:7

    Topics: Animals; Brain; Cognition; Discrimination Learning; Fear; Kynurenic Acid; Male; Microdialysis; Prefrontal Cortex; Pyrazoles; Rats; Rats, Sprague-Dawley; Stress, Psychological

2020
Designing a natural inhibitor against human kynurenine aminotransferase type II and a comparison with PF-04859989: a computational effort against schizophrenia.
    Journal of biomolecular structure & dynamics, 2022, Volume: 40, Issue:15

    Topics: Enzyme Inhibitors; Humans; Kynurenic Acid; Pyrazoles; Schizophrenia; Transaminases

2022