kynurenic acid and niacinamide

kynurenic acid has been researched along with niacinamide in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199022 (64.71)18.7374
1990's4 (11.76)18.2507
2000's1 (2.94)29.6817
2010's5 (14.71)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Bühlen, E; Bühner, R; Byrd, DJ; Kochen, W1
Bender, DA; Njagi, EN2
Brown, RR; Madsen, PO; Price, JM; Wolf, H1
Brown, RR; Hankes, LV; Lippincott, S; Schmaeler, M2
Boucek, RJ; Dietrich, LS; Hlavackova, V1
Bowman, AL; Hogue, DE; Travis, HF; Warner, RG1
Brown, RR; Hankes, LV1
Brown, RR; Leklem, JE; Woodford, J1
Crawford, MA; Hansen, IL; Lopez, A1
Brown, RR; Burney, SW; Friedell, GH; Price, JM1
Hardy, J; Heeley, AF; Heeley, ME; Soothill, JF1
Brown, RR; Price, JM; Yess, N1
Leklem, JE1
Curzon, G; Green, AR1
Berg, CP; Loh, HH1
Allegri, G; Costa, C; Crepaldi, G; De Antoni, A; Muggeo, M1
Houpt, JB; Hunt, M; Ogryzlo, MA1
Brown, RR; Hankes, LV; Jansen, CR; Leklem, J; Mekel, RC1
Masana, Y; Nakagawa, I; Suzuki, T; Takahashi, T1
Perkins, MN; Stone, TW1
Hayakawa, T; Kondo, T; Mushiage, M; Shibata, K; Tsuge, H1
Kondo, T; Miki, A; Shibata, K1
PASQUARIELLO, G1
MAINARDI, L; TENCONI, LT1
Fukuwatari, T; Shibata, K3
Fukuwatari, T; Hiratsuka, C; Saito, K; Sano, M; Sasaki, S; Shibata, K1
Fukuwatari, T; Funakoshi, H; Kadota, E; Kanai, M; Nakamura, T; Sano, M; Shibata, K; Terakata, M1
Shibata, K1
Fathi, M; Hajibeygi, R; Jazi, K; Klegeris, A; McElhinney, A; Sayehmiri, F; Shool, S; Sodeifian, F; Tavasol, A; Tavirani, MR; Vakili, K; Yaghoobpoor, S1
Axelsson, J; Balter, LJ; Erhardt, S; Lasselin, J; Lekander, M; Li, X; Olsson, MJ; Schwieler, L1

Reviews

4 review(s) available for kynurenic acid and niacinamide

ArticleYear
Testing the functional capacity of the tryptophan-niacin pathway in man by analysis of urinary metabolites.
    Advances in metabolic disorders, 1965, Volume: 2

    Topics: Adult; Amides; Amines; Chromatography, Ion Exchange; Equipment and Supplies; Female; Hormones; Humans; Indican; Ion Exchange Resins; Kynurenic Acid; Male; Metabolism, Inborn Errors; Methods; Niacinamide; Nicotinic Acids; Phenols; Pregnancy; Pyridoxine; Spectrophotometry; Tryptophan; Vitamins; Xanthurenates

1965
Quantitative aspects of tryptophan metabolism in humans and other species: a review.
    The American journal of clinical nutrition, 1971, Volume: 24, Issue:6

    Topics: Age Factors; Amides; Animals; Carbon Isotopes; Cats; Dogs; Female; Glucuronates; Glycine; Hippurates; Humans; Hydroxyindoleacetic Acid; Indican; Kynurenic Acid; Kynurenine; Lysine; Male; Mice; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Pyridones; Pyridoxine; Rats; Serotonin; Sex Factors; Species Specificity; Swine; Time Factors; Tryptophan; Xanthurenates

1971
Organ Co-Relationship in Tryptophan Metabolism and Factors That Govern the Biosynthesis of Nicotinamide from Tryptophan.
    Journal of nutritional science and vitaminology, 2018, Volume: 64, Issue:2

    Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Diet; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Liver; Niacinamide; Nutritional Status; Pentosyltransferases; Quinolinic Acid; Tryptophan; Vitamin B Deficiency; Xanthurenates

2018
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; NAD; Niacinamide; Parkinson Disease; Tryptophan

2022

Trials

3 trial(s) available for kynurenic acid and niacinamide

ArticleYear
Studies on tryptophan metabolism in male subjects treated with female sex hormones.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 31, Issue:4

    Topics: Aminohippuric Acids; Chlorotrianisene; Chromatography, Ion Exchange; Clinical Trials as Topic; Diethylstilbestrol; Glucuronates; Humans; Indican; Isonicotinic Acids; Kynurenic Acid; Kynurenine; Male; Mestranol; Niacinamide; Norethindrone; Norethynodrel; ortho-Aminobenzoates; Progestins; Prostatic Diseases; Prostatic Hyperplasia; Prostatitis; Pyridones; Pyridoxine; Spectrophotometry; Tryptophan; Tryptophan Oxygenase; Xanthurenates

1970
Supplementing healthy women with up to 5.0 g/d of L-tryptophan has no adverse effects.
    The Journal of nutrition, 2013, Volume: 143, Issue:6

    Topics: Adolescent; Adult; Biomarkers; Body Mass Index; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Humans; Kynurenic Acid; Kynurenine; Niacinamide; ortho-Aminobenzoates; Placebos; Tryptophan; Young Adult

2013
Lipopolysaccharide-induced changes in the kynurenine pathway and symptoms of sickness behavior in humans.
    Psychoneuroendocrinology, 2023, Volume: 153

    Topics: Adult; Female; Humans; Illness Behavior; Kynurenic Acid; Kynurenine; Lipopolysaccharides; Niacinamide; Young Adult

2023

Other Studies

27 other study(ies) available for kynurenic acid and niacinamide

ArticleYear
[Studies on tryptophan metabolism in untreated phenylketonuric patients].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1975, Volume: 13, Issue:1

    Topics: Acetophenones; Adolescent; Adult; Biotransformation; Child; Child, Preschool; Chromatography, Ion Exchange; Chromatography, Thin Layer; Female; Humans; Kynurenic Acid; Kynurenine; Male; Mass Spectrometry; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Phenylalanine; Phenylketonurias; Quinolines; Tryptophan; Xanthurenates

1975
Tryptophan metabolism in mice infected with Schistosoma mansoni.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Cells, Cultured; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Niacinamide; Schistosomiasis mansoni; Serotonin; Tryptophan; Xanthurenates

1991
Schistosoma mansoni: effects on tryptophan metabolism in mice.
    Experimental parasitology, 1990, Volume: 70, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Niacinamide; Oxidation-Reduction; Pyridoxine; Schistosomiasis mansoni; Tryptophan

1990
Effects of L-tryptophan load on the metabolism of tryptophan-2-C14 in man.
    The Journal of laboratory and clinical medicine, 1967, Volume: 69, Issue:2

    Topics: Aged; Aminohippuric Acids; Carbon Dioxide; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Niacinamide; Pyridines; Pyridones; Tryptophan; Tryptophan Oxygenase; Xanthurenates

1967
Tryptophan metabolism during the mid-period of embryonic development (chick).
    Biochimica et biophysica acta, 1967, Aug-29, Volume: 141, Issue:3

    Topics: Animals; Body Fluids; Chick Embryo; Chromatography, Gas; Chromatography, Paper; Hydrolases; Kynurenic Acid; Liver; Niacinamide; Nicotinic Acids; Pyridines; Tryptophan; Xanthurenates

1967
Vitamin B6 requirement of the mink.
    The Journal of nutrition, 1968, Volume: 95, Issue:4

    Topics: Animal Nutritional Physiological Phenomena; Animals; Diet; Female; Growth; Kynurenic Acid; Male; Mink; Niacinamide; Pyridoxine; Time Factors; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates

1968
Metabolism of D- and L-kynurenine-keto-14C in rats and the effects of unlabeled enantiomers.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 129, Issue:1

    Topics: Animals; Autoradiography; Carbon Dioxide; Carbon Isotopes; Chromatography, Paper; Injections, Intraperitoneal; Kynurenic Acid; Kynurenine; Methods; Niacinamide; Nicotinic Acids; Pyridines; Rats; Stereoisomerism; Xanthurenates

1968
Comparative tryptophan metabolism in cats and rats: differences in adaptation of tryptophan oxygenase and in vivo metabolism of tryptophan, kynurenine and hydroxykynurenine.
    Comparative biochemistry and physiology, 1969, Oct-01, Volume: 31, Issue:1

    Topics: Amino Acids; Aminohippuric Acids; Animals; Cats; Enzyme Induction; Glucuronates; Hydrocortisone; Indican; Kynurenic Acid; Kynurenine; Male; Niacinamide; ortho-Aminobenzoates; Phenylbutyrates; Rats; Species Specificity; Sulfates; Tryptophan; Tryptophan Oxygenase; Urinary Bladder Neoplasms; Xanthurenates

1969
The excretion of 3-hydroxyanthranilic and quinolinic acid in Uganda Africans.
    British journal of cancer, 1969, Volume: 23, Issue:3

    Topics: Adult; Analysis of Variance; Creatinine; Diet; Edible Grain; Female; Fruit; Humans; Kynurenic Acid; Male; Manihot; Niacinamide; ortho-Aminobenzoates; Plants, Edible; Pyridines; Tryptophan; Uganda; Urinary Bladder Neoplasms; Xanthurenates

1969
Lack of effect of smoking on the excretion of tryptophan metabolites by man.
    Cancer research, 1970, Volume: 30, Issue:3

    Topics: Adult; Aminohippuric Acids; Female; Glucuronates; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Niacinamide; Pyridinium Compounds; Smoking; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates

1970
A disorder of tryptophan metabolism in chronic granulomatous disease.
    Archives of disease in childhood, 1970, Volume: 45, Issue:242

    Topics: Child; Child, Preschool; Chromatography, Paper; Chronic Disease; Granuloma; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infections; Kynurenic Acid; Kynurenine; Lymphadenitis; Male; Niacinamide; Pyridoxine; Tryptophan; Xanthurenates

1970
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates

1970
Conversion of D-tryptophan to nicotinic acid in the rat.
    The Journal of nutrition, 1971, Volume: 101, Issue:12

    Topics: Animals; Deficiency Diseases; Indoles; Kidney; Kynurenic Acid; Kynurenine; Liver; Male; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyruvates; Rats; Stereoisomerism; Sulfuric Acids; Tryptophan; Xanthurenates

1971
The influence of simultaneous administration of vitamin B 6 and nicotinamide on tryptophan metabolism in Hodgkin's disease.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 40, Issue:1

    Topics: Acylation; Administration, Oral; Aminohippuric Acids; Hodgkin Disease; Humans; Hydroxylation; Infusions, Parenteral; Kynurenic Acid; Kynurenine; Methyl Ethers; Niacinamide; ortho-Aminobenzoates; Pyridoxine; Tryptophan; Xanthurenates

1972
Tryptophan metabolism in man (with special reference to rheumatoid arthritis and scleroderma).
    Seminars in arthritis and rheumatism, 1973, Volume: 2, Issue:4

    Topics: Arthritis, Rheumatoid; Aspirin; Cystinuria; Drug Synergism; Edetic Acid; Humans; Kynurenic Acid; Kynurenine; Methods; Niacinamide; Penicillamine; Pyridoxine; Scleroderma, Systemic; Tryptophan; Xanthurenates

1973
Abnormal tryptophan metabolism in patients with scurvy-type skin.
    Biochemical medicine, 1973, Volume: 7, Issue:1

    Topics: Acetates; Adult; Aminohippuric Acids; Black or African American; Black People; Ethnicity; Glucuronates; Hemosiderosis; Humans; Indoles; Kynurenic Acid; Kynurenine; Male; NAD; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Scurvy; South Africa; Sulfuric Acids; Tryptophan; Xanthurenates

1973
Effect in man of the addition of tryptophan oniacin to the diet on the excretion of their metabolites.
    The Journal of nutrition, 1969, Volume: 99, Issue:3

    Topics: Creatinine; Diet; Female; Humans; Kynurenic Acid; NAD; NADP; Niacinamide; Nicotinic Acids; Nitrogen; Pyridones; Tryptophan; Urea; Xanthurenates

1969
An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid.
    Brain research, 1982, Sep-09, Volume: 247, Issue:1

    Topics: Acetylcholine; Animals; Aspartic Acid; Cerebral Cortex; Convulsants; Drug Interactions; Kynurenic Acid; Kynurenine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Niacinamide; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats

1982
Effects of vitamin B6 deficiency on the conversion ratio of tryptophan to niacin.
    Bioscience, biotechnology, and biochemistry, 1995, Volume: 59, Issue:11

    Topics: Animals; Diet; Feeding Behavior; Kynurenic Acid; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Vitamin B 6 Deficiency; Weight Gain; Xanthurenates

1995
Increased conversion ratio of tryptophan to niacin in severe food restriction.
    Bioscience, biotechnology, and biochemistry, 1998, Volume: 62, Issue:3

    Topics: Animals; Food Deprivation; Kynurenic Acid; Male; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Xanthurenates

1998
METABOLISM OF 3-HYDROXYANTHRANILIC ACID-CARBOXYL-C14 IN THE HUMAN.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: 3-Hydroxyanthranilic Acid; Achondroplasia; Blood; Carbon Isotopes; Chromatography; Hippurates; Humans; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Rats; Research; Tryptophan; Urine; Xanthurenates

1964
[RESEARCH ON THE TRYPTOPHAN--NICOTINIC ACID PATHWAY IN DIABETES MELLITUS].
    Acta vitaminologica, 1964, Volume: 18

    Topics: Diabetes Mellitus; Geriatrics; Hippurates; Insulin; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Niacinamide; Nicotinic Acids; Research; Tryptophan; Urine

1964
[CONTRIBUTION TO THE STUDY OF METABOLITES OF THE TRYPTOPHAN TO NICOTINIC ACID PATHWAY IN RELATION TO SEX].
    Acta vitaminologica, 1964, Volume: 18

    Topics: Humans; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Niacinamide; Nicotinic Acids; Research; Sex; Tryptophan; Urine; Xanthurenates

1964
Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2007, Volume: 77, Issue:4

    Topics: 3-Hydroxyanthranilic Acid; Adult; Chromatography, High Pressure Liquid; Feedback, Physiological; Female; Humans; Kynurenic Acid; Niacinamide; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan; Xanthurenates

2007
The metabolites in the tryptophan degradation pathway might be useful to determine the tolerable upper intake level of tryptophan intake in rats.
    The Journal of nutrition, 2012, Volume: 142, Issue:12

    Topics: Adult; Animals; Female; Humans; Kynurenic Acid; Male; Niacinamide; No-Observed-Adverse-Effect Level; Nutritional Requirements; ortho-Aminobenzoates; Rats; Rats, Wistar; Tryptophan; Vitamins

2012
The niacin required for optimum growth can be synthesized from L-tryptophan in growing mice lacking tryptophan-2,3-dioxygenase.
    The Journal of nutrition, 2013, Volume: 143, Issue:7

    Topics: 3-Hydroxyanthranilic Acid; Animals; Body Weight; Diet; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Niacin; Niacinamide; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase; Xanthurenates

2013
Large amounts of picolinic acid are lethal but small amounts increase the conversion of tryptophan-nicotinamide in rats.
    Journal of nutritional science and vitaminology, 2014, Volume: 60, Issue:5

    Topics: Animals; Body Weight; Carboxy-Lyases; Dose-Response Relationship, Drug; Iron Chelating Agents; Kynurenic Acid; Liver; Male; Niacinamide; ortho-Aminobenzoates; Pentosyltransferases; Picolinic Acids; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Xanthurenates

2014