Compounds > kynurenic acid

kynurenic acid and anthranilic acid

kynurenic acid has been researched along with anthranilic acid in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199020 (32.79)18.7374
1990's5 (8.20)18.2507
2000's10 (16.39)29.6817
2010's20 (32.79)24.3611
2020's6 (9.84)2.80

Authors

AuthorsStudies
Fukui, S; Rapoport, SI; Schwarcz, R; Smith, QR; Takada, Y1
Abdel-Hamied, HA; Abdel-Tawab, GA; Aboul-Azm, T; Ebied, SA; el-Kholy, ZA; el-Sharaky, AS; el-Toukhy, MA1
Boni, RL; Markey, SP; Naritsin, DB1
Carlà, V; Carpenedo, R; Chiarugi, A; Lombardi, G; Mattoli, L; Moroni, F; Pellicciari, R; Russi, P1
Guzeva, VI; Melnikova, NV; Mikhailov, IB1
Goodman, CB; Heyliger, SO; Ngong, JM; Soliman, KF1
Baraldi, M; Cannazza, G; Chiarugi, A; Parenti, C; Zanoli, P1
Buczko, W; Mysliwiec, P; Pawlak, D; Tankiewicz, A1
Buczko, W; Malyszko, J; Mysliwiec, M; Pawlak, D; Pawlak, K1
HELLSTROM, B; VASSELLA, F; WENGLE, B1
BEHRMAN, EJ; STELLA, EJ1
ALLEGRI, G; BENASSI, CA; PERISSINOTTO, B2
ALLEGRI, G; BENASSI, CA; BENASSI, P; RABASSINI, A1
CREPALDI, G; PARPAJOLA, A1
MIYATAKE, M; SHIBA, S; TERAWAKI, A1
MENCZYK, Z1
BROWN, RR; HANKES, LV; LIPPINCOTT, S; SCHMAELER, M1
BROWN, RR; FLINN, JH; PRICE, JM; YESS, N1
CLAMP, JR; KOMROWER, GM; WESTALL, RG; WILSON, V1
BROWN, RR; BRYAN, GT; PRICE, JM2
BROWN, RR; BRYAN, GT; MORRIS, CR; PRICE, JM1
HATANAKA, M; HAYAISHI, O; KUNO, S; KURIHARA, N; NAKAJIMA, M; TANIUCHI, H1
ABUL-FADL, MA; KHALAFALLAH, AS1
PINALS, RS1
ALLERT, U; MELCHING, HJ; STREFFER, C1
CAREDDU, P; MAINARDI, L; TENCONI, LT1
Fukuoka, S; Fukuwatari, T; Ohsaki, S; Sasaki, R; Shibata, K; Suzuki, Y1
Darlington, LG; Forrest, CM; Mackay, GM; Oxford, L; Stone, TW; Stoy, N1
da Costa Ferreira, G; de Souza Wyse, AT; Dutra-Filho, CS; Duval Wannmacher, CM; Latini, A; Schuck, PF; Tonin, A; Viegas, CM; Wajner, M1
Buczko, P; Dziemiańczyk, D; Grabowska, SZ; Pawlak, D; Szarmach, IJ; Tankiewicz, A1
Fukuwatari, T; Shibata, K3
Fukuwatari, T; Okuno, A; Shibata, K1
Kowalewska, A; Mysliwiec, M; Pawlak, D; Pawlak, K1
Molina-Carballo, A; Muñoz-Hoyos, A; Romero, J; Uberos, J1
Bien, B; Gulaj, E; Pawlak, D; Pawlak, K1
Du Preez, JL; Harvey, BH; Möller, M1
Eussen, SJ; Midttun, Ø; Nygård, O; Tell, GS; Theofylaktopoulou, D; Ueland, PM; Ulvik, A; Vollset, SE1
Fukuwatari, T; Hiratsuka, C; Saito, K; Sano, M; Sasaki, S; Shibata, K1
Gregory, JF; Nijhout, HF; Reed, MC; Rios-Avila, L; Sitren, HS1
Beconi, M; Bonelli, F; Caretti, F; Chan, K; Dominguez, C; Herbst, T; Lyons, K; Monteagudo, E; Munoz-Sanjuan, I; Orsale, MV; Orsatti, L; Speziale, R; Toledo-Sherman, L; Veneziano, M; Zini, M1
Brody, LC; Brosnan, JT; Brosnan, ME; Deac, OM; Fan, R; Gibney, ER; Laird, E; Midttun, Ø; Mills, JL; Molloy, AM; Shane, B; Ueland, PM; Wang, Y1
Dierkes, J; Drevon, CA; Gudbrandsen, OA; Karlsson, T; Midttun, Ø; Nygård, O; Pedersen, ER; Strand, E; Ueland, PM; Øyen, J1
Dabrowska, M; Jasiewicz, M; Kaminski, KA; Kazimierczyk, R; Knapp, M; Moniuszko, M; Musial, WJ; Pawlak, D; Rusak, M1
Capi, M; Curto, M; Fazio, F; Giamberardino, MA; Lionetto, L; Martelletti, P; Negro, A; Nicoletti, F; Perugino, F; Simmaco, M1
Capi, M; Curto, M; Fazio, F; Giamberardino, MA; Lionetto, L; Martelletti, P; Negro, A; Nicoletti, F; Simmaco, M1
Allorge, D; Bortolotti, P; Dessein, R; Faure, E; Faure, K; Grandjean, T; Guery, BP; Hennart, B; Jausions, G; Kipnis, E; Le Gouellec, A; Thepaut, M; Thieffry, C; Toussaint, B1
Cobb, SR; Dalton, RN; Darlington, LG; Forrest, CM; Kennedy, PG; Rodgers, J; Stone, TW; Turner, C1
Bengesser, SA; Birner, A; Dalkner, N; Fellendorf, FT; Fuchs, D; Hamm, C; Herzog-Eberhard, S; Kapfhammer, HP; Maget, A; Mangge, H; Moll, N; Pilz, R; Platzer, M; Queissner, R; Rauch, P; Reininghaus, B; Reininghaus, EZ; Schütze, G; Schwarz, M; Zelzer, S1
Inglot, M; Laskus, T; Malyszczak, K; Pawlak, D; Pawlowski, T; Radkowski, M; Zalewska, M1
Badawy, AA1
Baldessarini, RJ; Comparelli, A; Corigliano, V; Curto, M; Fazio, F; Ferracuti, S; Lionetto, L; Nicoletti, F; Simmaco, M1
Allers, KA; Harkin, A; McLoughlin, DM; Ryan, KM1
Bugajska, J; Inglot, M; Janocha-Litwin, J; Malyszczak, K; Marciniak, D; Pawlak, D; Pawlowski, T; Zalewska, M1
Di Pasquale, P; Dischinger, K; Dreger, P; Luft, T; Monteagudo, E; Müller-Tidow, C; Orsatti, L; Radujkovic, A; Speziale, R; Stiehl, T1
Bernstein, HG; Dobrowolny, H; Fuchs, D; Guest, PC; Oxenkrug, G; Roeser, J; Steiner, J; Summergrad, P1
Fathi, M; Hajibeygi, R; Jazi, K; Klegeris, A; McElhinney, A; Sayehmiri, F; Shool, S; Sodeifian, F; Tavasol, A; Tavirani, MR; Vakili, K; Yaghoobpoor, S1
Bakker, L; Choe, K; J P M Eussen, S; Kenis, G; Köhler, S; Ramakers, IHGB; Rutten, BPF; Staals, J; Ueland, PM; Ulvik, A; van den Hove, DLA; van Oostenbrugge, RJ; Verhey, FRJ1

Reviews

1 review(s) available for kynurenic acid and anthranilic acid

ArticleYear
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; NAD; Niacinamide; Parkinson Disease; Tryptophan

2022

Trials

1 trial(s) available for kynurenic acid and anthranilic acid

ArticleYear
Supplementing healthy women with up to 5.0 g/d of L-tryptophan has no adverse effects.
    The Journal of nutrition, 2013, Volume: 143, Issue:6

    Topics: Adolescent; Adult; Biomarkers; Body Mass Index; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Humans; Kynurenic Acid; Kynurenine; Niacinamide; ortho-Aminobenzoates; Placebos; Tryptophan; Young Adult

2013

Other Studies

59 other study(ies) available for kynurenic acid and anthranilic acid

ArticleYear
Blood-brain barrier transport of kynurenines: implications for brain synthesis and metabolism.
    Journal of neurochemistry, 1991, Volume: 56, Issue:6

    Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains

1991
The correlation between certain tryptophan metabolites and the N-nitrosamine content in the urine of bilharzial bladder cancer patients.
    The Journal of urology, 1986, Volume: 135, Issue:4

    Topics: 3-Hydroxyanthranilic Acid; Adult; Aminohippuric Acids; Colorimetry; Humans; Indican; Kynurenic Acid; Kynurenine; Male; Middle Aged; Nitrosamines; ortho-Aminobenzoates; Schistosomiasis haematobia; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates

1986
Pentafluorobenzylation method for quantification of acidic tryptophan metabolites using electron capture negative ion mass spectrometry.
    Analytical chemistry, 1995, Mar-01, Volume: 67, Issue:5

    Topics: Fluorobenzenes; Kynurenic Acid; Kynurenine; Mass Spectrometry; Molecular Structure; ortho-Aminobenzoates; Picolinic Acids; Quaternary Ammonium Compounds; Quinolinic Acid; Tryptophan; Xanthurenates

1995
Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities.
    Neuroscience, 1994, Volume: 61, Issue:2

    Topics: Alanine; Animals; Anticonvulsants; Brain Chemistry; Electroshock; Excitatory Amino Acid Antagonists; Hydrolases; Hypnotics and Sedatives; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; Motor Activity; Neuroglia; Niacin; ortho-Aminobenzoates; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate

1994
The kynurenines and the seizures.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Animals; Cerebral Ventricles; Electroencephalography; Hippocampus; Kynurenic Acid; Kynurenine; Microinjections; Neurons; ortho-Aminobenzoates; Penicillin G; Quinolinic Acid; Rats; Seizures

1996
The analgesic effects of tryptophan and its metabolites in the rat.
    Pharmacological research, 1998, Volume: 38, Issue:4

    Topics: Analgesics; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hypolipidemic Agents; Iron Chelating Agents; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Pain; Picolinic Acids; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex; Tryptophan; Xanthurenates

1998
Changes in kynurenic, anthranilic, and quinolinic acid concentrations in rat brain tissue during development.
    Neurochemical research, 2001, Volume: 26, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Brain; Embryo, Mammalian; Female; Kynurenic Acid; Male; ortho-Aminobenzoates; Osmolar Concentration; Quinolinic Acid; Rats; Rats, Sprague-Dawley

2001
Tryptophan metabolism via the kynurenine pathway in experimental chronic renal failure.
    Nephron, 2002, Volume: 90, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Creatinine; Kidney; Kidney Failure, Chronic; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Quinolinic Acid; Rats; Rats, Wistar; Time Factors; Tryptophan; Urea; Xanthurenates

2002
Accumulation of toxic products degradation of kynurenine in hemodialyzed patients.
    International urology and nephrology, 2001, Volume: 33, Issue:2

    Topics: Female; Humans; Kidney; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Quinolinic Acid; Renal Dialysis; Tryptophan; Uremia; Xanthurenates

2001
Urinary excretion of tryptophan metabolites in the healthy infant.
    Pediatrics, 1962, Volume: 30

    Topics: Chromatography; Humans; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Tryptophan; Urine

1962
ENRICHMENT PROCEDURES FOR THE ISOLATION OF TRYPTOPHAN-OXIDIZING ORGANISMS.
    Journal of bacteriology, 1963, Volume: 85

    Topics: Culture Media; Kynurenic Acid; ortho-Aminobenzoates; Oxidation-Reduction; Pseudomonas; Tryptophan

1963
THE METABOLISM OF TRYPTOPHAN IN PATIENTS WITH BLADDER CANCER AND OTHER UROLOGICAL DISEASES.
    Clinica chimica acta; international journal of clinical chemistry, 1963, Volume: 8

    Topics: Geriatrics; Humans; Kidney Neoplasms; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Prostatic Neoplasms; Proteins; Tryptophan; Urinary Bladder Diseases; Urinary Bladder Neoplasms; Urine

1963
TRYPTOPHAN METABOLISM IN SPECIAL PAIRS OF TWINS.
    Clinica chimica acta; international journal of clinical chemistry, 1964, Volume: 9

    Topics: Chromatography; Diseases in Twins; Genetics, Medical; Kynurenic Acid; Kynurenine; Metabolic Diseases; ortho-Aminobenzoates; Proteins; Schizophrenia; Spectrophotometry; Tryptophan; Urine; Xanthurenates

1964
EXCRETION OF TRYPTOPHAN METABOLITES IN DIFFERENT FORMS OF HAEMOBLASTOSIS.
    Clinica chimica acta; international journal of clinical chemistry, 1964, Volume: 9

    Topics: Cortisone; Cyclophosphamide; Genetic Diseases, X-Linked; Hodgkin Disease; Humans; Kynurenic Acid; Kynurenine; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphatic Diseases; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Multiple Myeloma; ortho-Aminobenzoates; Phenylbutazone; Polycythemia Vera; Proteins; Pyridoxal Phosphate; Pyridoxine; Sarcoma; Severe Combined Immunodeficiency; Tryptophan; Urine; Xanthurenates

1964
STUDIES ON THE TRYPTOPHAN METABOLISM IN TUMOR-BEARING ANIMALS.
    Gan, 1964, Volume: 55

    Topics: Animals; Kynurenic Acid; Kynurenine; Liver; Neoplasms; Neoplasms, Experimental; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Proteins; Rats; Research; Sarcoma; Tryptophan; Urine; Xanthurenates

1964
A METHOD FOR THE DETERMINATION OF EIGHT TRYPTOPHAN METABOLITES IN BIOLOGICAL FLUIDS.
    Canadian journal of medical technology, 1964, Volume: 26

    Topics: Blood Proteins; Cerebrospinal Fluid Proteins; Chromatography; Humans; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Spectrophotometry; Tryptophan; Urine; Xanthurenates

1964
METABOLISM OF 3-HYDROXYANTHRANILIC ACID-CARBOXYL-C14 IN THE HUMAN.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: 3-Hydroxyanthranilic Acid; Achondroplasia; Blood; Carbon Isotopes; Chromatography; Hippurates; Humans; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Rats; Research; Tryptophan; Urine; Xanthurenates

1964
URINARY EXCRETION OF TRYPTOPHAN METABOLITES IN PATIENTS WITH RENAL PELVIS AND PARENCHYMA TUMOURS.
    Urologia internationalis, 1964, Volume: 17

    Topics: Chromatography; Humans; Kidney Neoplasms; Kidney Pelvis; Kynurenic Acid; Kynurenine; Neoplasms; ortho-Aminobenzoates; Spectrophotometry; Tryptophan; Urine; Xanthurenates

1964
EXCRETION OF TRYPTOPHAN METABOLITES BY PATIENTS WITH RHEUMATOID ARTHRITIS.
    Arthritis and rheumatism, 1964, Volume: 7

    Topics: Arthritis; Arthritis, Rheumatoid; Biomedical Research; Chromatography; Gout; Hippurates; Indoles; Kynurenic Acid; Kynurenine; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Proteins; Psoriasis; Pyridines; Pyridoxine; Spondylitis; Tryptophan; Urine; Xanthurenates

1964
HYDROXYKYNURENINURIA: A CASE OF ABNORMAL TRYPTOPHAN METABOLISM PROBABLY DUE TO A DEFICIENCY OF KYNURENINASE.
    Archives of disease in childhood, 1964, Volume: 39

    Topics: Amino Acid Metabolism, Inborn Errors; Child; Chromatography; Electrophoresis; Humans; Hydrolases; Kynurenic Acid; Kynurenine; Metabolic Diseases; Niacin; ortho-Aminobenzoates; Proteins; Pyridoxine; Spectrophotometry; Tryptophan; Urine; Xanthurenates

1964
INCIDENCE OF MOUSE BLADDER TUMORS FOLLOWING IMPLANTATION OF PARAFFIN PELLETS CONTAINING CERTAIN TRYPTOPHAN METABOLITES.
    Cancer research, 1964, Volume: 24

    Topics: Animals; Carcinogens; Chromatography; Incidence; Kynurenic Acid; Mice; Neoplasms; Neoplasms, Experimental; ortho-Aminobenzoates; Paraffin; Quinolines; Research; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates

1964
IN VIVO ELUTION OF TRYPTOPHAN METABOLITES AND OTHER AROMATIC NITROGEN COMPOUNDS FROM CHOLESTEROL PELLETS IMPLANTED INTO MOUSE BLADDERS.
    Cancer research, 1964, Volume: 24

    Topics: Amines; Animals; Carcinogens; Cholesterol; Fluorenes; Hydroxylamines; Kynurenic Acid; Kynurenine; Metabolism; Mice; Naphthalenes; Nitrogen; Nitrogen Compounds; ortho-Aminobenzoates; Pharmacology; Quinolines; Research; Stearic Acids; Tryptophan; Urinary Bladder; Urinary Bladder Neoplasms; Xanthurenates

1964
MOUSE BLADDER CARCINOGENICITY OF CERTAIN TRYPTOPHAN METABOLITES AND OTHER AROMATIC NITROGEN COMPOUNDS SUSPENDED IN CHOLESTEROL.
    Cancer research, 1964, Volume: 24

    Topics: Amines; Animals; Carcinogens; Cholesterol; Fluorenes; Hydroxylamines; Kynurenic Acid; Kynurenine; Metabolism; Mice; Naphthalenes; Neoplasms; Neoplasms, Experimental; Nitrogen; Nitrogen Compounds; ortho-Aminobenzoates; Pharmacology; Quinolines; Research; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates

1964
ENZYMATIC FORMATION OF CATECHOL FROM ANTHRANILIC ACID.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Benzene; Benzoates; Carbon Isotopes; Catechols; Glycols; Kynurenic Acid; Levulinic Acids; Metabolism; Mixed Function Oxygenases; NAD; NADP; ortho-Aminobenzoates; Oxidoreductases; Pseudomonas; Research; Salicylic Acid; Tryptophan

1964
STUDIES ON THE URINARY EXCRETION OF CERTAIN TRYPTOPHAN METABOLITES BEFORE AND AFTER TRYPTOPHAN LOADING DOSE IN BILHARZIASIS, BILHARZIAL BLADDER CANCER AND CERTAIN OTHER TYPES OF MALIGNANCIES IN EGYPT.
    British journal of cancer, 1964, Volume: 13

    Topics: Amino Acids; Egypt; Epidemiology; Fluids and Secretions; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Neoplasms; ortho-Aminobenzoates; Schistosomiasis; Tryptophan; Urinary Bladder Neoplasms; Urine; Xanthurenates

1964
TRYPTOPHAN METABOLISM IN RHEUMATIC DISEASE.
    Arthritis and rheumatism, 1964, Volume: 7

    Topics: Amino Acids; Arthritis; Arthritis, Rheumatoid; Chromatography; Humans; Kynurenic Acid; Kynurenine; Lupus Erythematosus, Systemic; ortho-Aminobenzoates; Rheumatic Diseases; Scleroderma, Systemic; Tryptophan; Urine; Xanthurenates

1964
[TUDIES ON BIOLOGICAL RADIATION PROTECTION. 53. THE EFFECT OF HISTAMINE ON RADIATION-INDUCED CHANGES IN AMINO ACID METABOLISM].
    Strahlentherapie, 1964, Volume: 124

    Topics: Amino Acids; Histamine; Kynurenic Acid; Kynurenine; Mice; ortho-Aminobenzoates; Pharmacology; Radiation Protection; Research; Urine

1964
[RESEARCH ON ELIMINATION OF METABOLITES OF THE TRYPTOPHAN TO NICOTINIC ACID PATHWAY IN INFANTS].
    Acta vitaminologica, 1964, Volume: 18

    Topics: Chromatography; Diet; Hippurates; Humans; Infant; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Tryptophan; Urine; Vitamins; Xanthurenates

1964
The effects of phthalate esters on the tryptophan-niacin metabolism.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: 3-Hydroxyanthranilic Acid; Animals; Dibutyl Phthalate; Diethylhexyl Phthalate; Kynurenic Acid; Liver; Male; NAD; Niacin; ortho-Aminobenzoates; Phthalic Acids; Plasticizers; Rats; Rats, Wistar; Tryptophan; Xanthurenates

2003
Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:11

    Topics: 3-Hydroxyanthranilic Acid; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethacin; Kynurenic Acid; Kynurenine; Lipid Peroxidation; Male; Middle Aged; Molecular Structure; Neopterin; ortho-Aminobenzoates; Osteoporosis; Sodium Salicylate; Tryptophan

2006
Kynurenines impair energy metabolism in rat cerebral cortex.
    Cellular and molecular neurobiology, 2007, Volume: 27, Issue:1

    Topics: 3-Hydroxyanthranilic Acid; Animals; Carbon Dioxide; Cerebral Cortex; Electron Transport; Energy Metabolism; Glucose; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Rats; Rats, Wistar

2007
Tryptophan and its metabolites in patients with oral squamous cell carcinoma: preliminary study.
    Advances in medical sciences, 2006, Volume: 51 Suppl 1

    Topics: Aged, 80 and over; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Female; Humans; Kynurenic Acid; Male; Middle Aged; Mouth Neoplasms; ortho-Aminobenzoates; Saliva; Tryptophan

2006
Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2007, Volume: 77, Issue:4

    Topics: 3-Hydroxyanthranilic Acid; Adult; Chromatography, High Pressure Liquid; Feedback, Physiological; Female; Humans; Kynurenic Acid; Niacinamide; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan; Xanthurenates

2007
Urinary excretory ratio of anthranilic acid/kynurenic acid as an index of the tolerable amount of tryptophan.
    Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:7

    Topics: Animals; Dietary Supplements; Dose-Response Relationship, Drug; Kynurenic Acid; Male; ortho-Aminobenzoates; Rats; Rats, Wistar; Tryptophan

2008
Kynurenine and its metabolites--kynurenic acid and anthranilic acid are associated with soluble endothelial adhesion molecules and oxidative status in patients with chronic kidney disease.
    The American journal of the medical sciences, 2009, Volume: 338, Issue:4

    Topics: Adult; Aged; Case-Control Studies; Female; Humans; Intercellular Adhesion Molecule-1; Kidney Failure, Chronic; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Oxidative Stress; Vascular Cell Adhesion Molecule-1

2009
Melatonin and elimination of kynurenines in children with Down's syndrome.
    Journal of pediatric endocrinology & metabolism : JPEM, 2010, Volume: 23, Issue:3

    Topics: Child; Child, Preschool; Circadian Rhythm; Down Syndrome; Female; Humans; Kynurenic Acid; Kynurenine; Male; Melatonin; ortho-Aminobenzoates; Oxidative Stress; Serotonin; Tryptophan

2010
Kynurenine and its metabolites in Alzheimer's disease patients.
    Advances in medical sciences, 2010, Volume: 55, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Female; Humans; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan

2010
Development and validation of a single analytical method for the determination of tryptophan, and its kynurenine metabolites in rat plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Jun-01, Volume: 898

    Topics: 3-Hydroxyanthranilic Acid; Animals; Charcoal; Chromatography, High Pressure Liquid; Depression; Kynurenic Acid; Kynurenine; Linear Models; Male; ortho-Aminobenzoates; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Schizophrenia; Social Isolation; Solid Phase Extraction; Tandem Mass Spectrometry; Tryptophan

2012
The metabolites in the tryptophan degradation pathway might be useful to determine the tolerable upper intake level of tryptophan intake in rats.
    The Journal of nutrition, 2012, Volume: 142, Issue:12

    Topics: Adult; Animals; Female; Humans; Kynurenic Acid; Male; Niacinamide; No-Observed-Adverse-Effect Level; Nutritional Requirements; ortho-Aminobenzoates; Rats; Rats, Wistar; Tryptophan; Vitamins

2012
A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study.
    Clinical and experimental immunology, 2013, Volume: 173, Issue:1

    Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Body Mass Index; Creatinine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Middle Aged; Motor Activity; Neopterin; Norway; ortho-Aminobenzoates; Reference Values; Smoking; Tryptophan; Xanthurenates

2013
A mathematical model of tryptophan metabolism via the kynurenine pathway provides insights into the effects of vitamin B-6 deficiency, tryptophan loading, and induction of tryptophan 2,3-dioxygenase on tryptophan metabolites.
    The Journal of nutrition, 2013, Volume: 143, Issue:9

    Topics: Animals; Brain; Contraceptives, Oral; Female; Humans; Hydrolases; Intestines; Kynurenic Acid; Kynurenine; Liver; Mice; Models, Theoretical; Muscles; ortho-Aminobenzoates; Rats; Transaminases; Tryptophan; Tryptophan Oxygenase; Vitamin B 6 Deficiency

2013
A single-run liquid chromatography mass spectrometry method to quantify neuroactive kynurenine pathway metabolites in rat plasma.
    Journal of pharmaceutical and biomedical analysis, 2015, Mar-25, Volume: 107

    Topics: Animals; Blood-Brain Barrier; Chromatography, High Pressure Liquid; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Plasma; Rats; Tryptophan

2015
Large amounts of picolinic acid are lethal but small amounts increase the conversion of tryptophan-nicotinamide in rats.
    Journal of nutritional science and vitaminology, 2014, Volume: 60, Issue:5

    Topics: Animals; Body Weight; Carboxy-Lyases; Dose-Response Relationship, Drug; Iron Chelating Agents; Kynurenic Acid; Liver; Male; Niacinamide; ortho-Aminobenzoates; Pentosyltransferases; Picolinic Acids; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Xanthurenates

2014
Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults.
    The Journal of nutrition, 2015, Volume: 145, Issue:4

    Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Arginine; Biomarkers; Dietary Supplements; Female; Healthy Volunteers; Humans; Kynurenic Acid; Kynurenine; Life Style; Male; Methionine; ortho-Aminobenzoates; Pyridoxal Phosphate; Sex Factors; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Xanthurenates; Young Adult

2015
Associations between intake of fish and n-3 long-chain polyunsaturated fatty acids and plasma metabolites related to the kynurenine pathway in patients with coronary artery disease.
    European journal of nutrition, 2017, Volume: 56, Issue:1

    Topics: 3-Hydroxyanthranilic Acid; Aged; Animals; Biomarkers; Body Mass Index; Cholesterol; Coronary Artery Disease; Cross-Sectional Studies; Energy Intake; Fatty Acids, Omega-3; Female; Fishes; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Neopterin; Norway; Nutrition Assessment; ortho-Aminobenzoates; Seafood; Triglycerides; Tryptophan; Xanthurenates

2017
Activity of the kynurenine pathway and its interplay with immunity in patients with pulmonary arterial hypertension.
    Heart (British Cardiac Society), 2016, Volume: 102, Issue:3

    Topics: Adult; Aged; Area Under Curve; Case-Control Studies; Disease Progression; Echocardiography, Doppler; Exercise Test; Female; Flow Cytometry; Humans; Hypertension, Pulmonary; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Prospective Studies; ROC Curve; T-Lymphocytes, Regulatory; Th17 Cells; Tryptophan

2016
Altered serum levels of kynurenine metabolites in patients affected by cluster headache.
    The journal of headache and pain, 2015, Volume: 17

    Topics: Adult; Cluster Headache; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan; Xanthurenates

2015
Altered kynurenine pathway metabolites in serum of chronic migraine patients.
    The journal of headache and pain, 2015, Volume: 17

    Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; Middle Aged; Migraine Disorders; ortho-Aminobenzoates; Quinolinic Acid; Tandem Mass Spectrometry; Tryptophan; Xanthurenates

2015
Tryptophan catabolism in Pseudomonas aeruginosa and potential for inter-kingdom relationship.
    BMC microbiology, 2016, 07-08, Volume: 16, Issue:1

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Host-Pathogen Interactions; Immunity, Innate; Kynurenic Acid; Kynurenine; Metabolic Networks and Pathways; Mice; Murinae; ortho-Aminobenzoates; Pseudomonas aeruginosa; Pseudomonas Infections; Transaminases; Tryptophan

2016
Kynurenine pathway metabolism following prenatal KMO inhibition and in Mecp2
    Neurochemistry international, 2016, Volume: 100

    Topics: Animals; Autism Spectrum Disorder; Brain; Chromatography, Liquid; Female; Kynurenic Acid; Kynurenine; Methyl-CpG-Binding Protein 2; ortho-Aminobenzoates; Pregnancy; Rats, Wistar; Tandem Mass Spectrometry; Tryptophan

2016
Increased breakdown of kynurenine towards its neurotoxic branch in bipolar disorder.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Adult; Bipolar Disorder; Brain; Case-Control Studies; Cognition; Depression; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Middle Aged; Multivariate Analysis; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan

2017
Alterations in the metabolism of tryptophan in patients with chronic hepatitis C six months after pegylated interferon-α 2a treatment.
    Psychoneuroendocrinology, 2018, Volume: 97

    Topics: Adult; Antiviral Agents; Depression; Depressive Disorder; Female; Hepatitis C; Hepatitis C, Chronic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-alpha; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Polyethylene Glycols; Recombinant Proteins; Tryptophan

2018
Hypothesis kynurenic and quinolinic acids: The main players of the kynurenine pathway and opponents in inflammatory disease.
    Medical hypotheses, 2018, Volume: 118

    Topics: Animals; Anti-Inflammatory Agents; Humans; Immunosuppressive Agents; Inflammation; Kynurenic Acid; Kynurenine; Male; Models, Theoretical; ortho-Aminobenzoates; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Wistar; Tryptophan

2018
Serum xanthurenic acid levels: Reduced in subjects at ultra high risk for psychosis.
    Schizophrenia research, 2019, Volume: 208

    Topics: Adolescent; Adult; Disease Progression; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Prodromal Symptoms; Psychotic Disorders; Quinolinic Acid; Risk; Schizophrenia; Tryptophan; Xanthurenates; Young Adult

2019
Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy.
    Brain, behavior, and immunity, 2020, Volume: 83

    Topics: 3-Hydroxyanthranilic Acid; Affect; Case-Control Studies; Electroconvulsive Therapy; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Picolinic Acids; Quinolinic Acid; Tryptophan; Xanthurenates

2020
The role of anthranilic acid in the increase of depressive symptoms and major depressive disorder during treatment for hepatitis C with pegylated interferon-α2a and oral ribavirin.
    Journal of psychiatry & neuroscience : JPN, 2021, 01-18, Volume: 46, Issue:1

    Topics: Adult; Antiviral Agents; Cross-Sectional Studies; Depression; Depressive Disorder, Major; Female; Hepatitis C, Chronic; Humans; Immunologic Factors; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-alpha; Kynurenic Acid; Kynurenine; Longitudinal Studies; Male; Middle Aged; ortho-Aminobenzoates; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Tryptophan

2021
Kynurenine pathway activation and deviation to anthranilic and kynurenic acid in fibrosing chronic graft-versus-host disease.
    Cell reports. Medicine, 2021, 10-19, Volume: 2, Issue:10

    Topics: Adolescent; Adult; Aged; Chemokine CXCL9; Female; Fibrosis; Gene Expression Regulation; Graft vs Host Disease; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interleukin-18; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Leukemia; Lymphoma; Male; Metabolic Networks and Pathways; Middle Aged; ortho-Aminobenzoates; Retrospective Studies; Riboflavin; Severity of Illness Index; Signal Transduction; Stem Cell Transplantation; Transplantation, Homologous; Tryptophan; Vitamin B 6

2021
Gender-specific elevation of plasma anthranilic acid in schizophrenia: Protection against glutamatergic hypofunction?
    Schizophrenia research, 2022, Volume: 243

    Topics: Humans; Kynurenic Acid; ortho-Aminobenzoates; Schizophrenia

2022
The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study.
    Journal of the neurological sciences, 2023, Nov-15, Volume: 454

    Topics: Biomarkers; Cognition; Female; Humans; Kynurenic Acid; Kynurenine; Male; Prospective Studies; Stroke

2023