kynurenic acid and 4-chlorokynurenine

kynurenic acid has been researched along with 4-chlorokynurenine in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (16.67)	18.2507
2000's	3 (50.00)	29.6817
2010's	2 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hokari, M; Schwarcz, R; Smith, QR; Wu, HQ	1
Lee, SC; Schwarcz, R; Wu, HQ	1
Guidetti, P; Schwarcz, R; Wu, HQ	1
Lee, SC; Schwarcz, R	1
Tan, L; Yu, JT	1
Schwarcz, R; Snodgrass, HR; Yaksh, TL	1

Reviews

1 review(s) available for kynurenic acid and 4-chlorokynurenine

Article	Year
The kynurenine pathway in neurodegenerative diseases: mechanistic and therapeutic considerations. Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2 Topics: Aging; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Enzyme Inhibitors; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Microglia; Molecular Targeted Therapy; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Quinolinic Acid; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Tryptophan	2012

Article

Year

The kynurenine pathway in neurodegenerative diseases: mechanistic and therapeutic considerations.

Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2

Topics: Aging; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Enzyme Inhibitors; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Microglia; Molecular Targeted Therapy; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Quinolinic Acid; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Tryptophan

2012

Other Studies

5 other study(ies) available for kynurenic acid and 4-chlorokynurenine

Article	Year
Facilitated brain uptake of 4-chlorokynurenine and conversion to 7-chlorokynurenic acid. Neuroreport, 1996, Dec-20, Volume: 8, Issue:1 Topics: Amino Acids; Animals; Biotransformation; Brain; Excitatory Amino Acid Antagonists; Kynurenic Acid; Kynurenine; Male; Perfusion; Prodrugs; Rats; Rats, Sprague-Dawley	1996
Systemic administration of 4-chlorokynurenine prevents quinolinate neurotoxicity in the rat hippocampus. European journal of pharmacology, 2000, Mar-03, Volume: 390, Issue:3 Topics: Animals; Brain Diseases; Dialysis Solutions; Hippocampus; Injections, Intraperitoneal; Kynurenic Acid; Kynurenine; Male; Microdialysis; Neuroprotective Agents; Prodrugs; Quinolinic Acid; Rats; Rats, Sprague-Dawley	2000
In situ produced 7-chlorokynurenate provides protection against quinolinate- and malonate-induced neurotoxicity in the rat striatum. Experimental neurology, 2000, Volume: 163, Issue:1 Topics: 3-Hydroxyanthranilic Acid; Animals; Biotransformation; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Infusions, Parenteral; Kynurenic Acid; Kynurenine; Male; Malonates; Neurons; Neuroprotective Agents; Prodrugs; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glycine	2000
Excitotoxic injury stimulates pro-drug-induced 7-chlorokynurenate formation in the rat striatum in vivo. Neuroscience letters, 2001, May-25, Volume: 304, Issue:3 Topics: Animals; Corpus Striatum; Injections, Intraperitoneal; Kynurenic Acid; Kynurenine; Male; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Osmolar Concentration; Prodrugs; Quinolinic Acid; Rats; Rats, Sprague-Dawley	2001
Characterization of the Effects of L-4-Chlorokynurenine on Nociception in Rodents. The journal of pain, 2017, Volume: 18, Issue:10 Topics: Amines; Analgesics; Animals; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Kynurenic Acid; Kynurenine; Male; Prodrugs; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord	2017