kynurenic acid has been researched along with 2-amino-5-phosphonovalerate in 257 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (15.18) | 18.7374 |
| 1990's | 167 (64.98) | 18.2507 |
| 2000's | 42 (16.34) | 29.6817 |
| 2010's | 9 (3.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Copenhagen, DR; Dixon, DB | 1 |
| Becker, DP; Hovda, DA; Katayama, Y; Kawamata, T; Yoshino, A | 1 |
| Aceves, J; Arias-Montaño, JA; Martínez-Fong, D | 1 |
| Berger, TW; Thiels, E; Weisz, DJ | 1 |
| Arellano, RO; Conde-Guerri, B; Matute, C; Miledi, R | 1 |
| DiMicco, JA; Soltis, RP | 2 |
| Bear, MF; Connors, BW; Press, WA | 1 |
| Dawes, E; Hankins, M; Ikeda, H | 1 |
| Di Loreto, S; Florio, T; Scarnati, E | 1 |
| Lipton, SA; Zhang, D | 1 |
| Ishii, T; Masu, M; Moriyoshi, K; Nakanishi, S; Sugihara, H | 1 |
| Lu, CL; Shaikh, MB; Siegel, A | 1 |
| Currie, SN; Stein, PS | 1 |
| Pinnock, RD | 1 |
| Kita, H; Nakanishi, H; Yamamoto, K | 1 |
| Uchida, K | 1 |
| Peeters, BW; Vanderheyden, PM | 1 |
| Dubner, R; Hylden, JL; Ren, K; Ruda, MA; Williams, GM | 1 |
| Kaba, H; Keverne, EB | 1 |
| Deschênes, M; Pinault, D | 1 |
| Aceves, J; Góngora-Alfaro, JL; Hernández, S; Martínez-Fong, D; Rosales, MG | 1 |
| Ivanova, SF; Sanzharovskiĭ, AV; Storozhuk, VM | 1 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Mody, I; Staley, KJ | 1 |
| Gottesman, J; Miller, RF | 1 |
| Chernevskaya, NI; Krishtal, OA; Obukhov, AG | 1 |
| Armstrong, DM; Costa, E; Mereu, G; Vicini, S | 1 |
| Kihara, M; Kubo, T; Misu, Y | 1 |
| Dudek, FE; Wuarin, JP | 1 |
| Baron, BM; Chi, EM; Harrison, BL; Kehne, JH; McCloskey, TC; Palfreyman, MG; Whitten, JP | 1 |
| Davidoff, RA; Hackman, JC | 1 |
| Sewell, WF; Starr, PA | 1 |
| Bandopadhyay, R; de Belleroche, J | 1 |
| Clark, AJ; Hastings, MH; Latimer, M; Stone, TW; Winn, P | 1 |
| Canton, H; Colpaert, F; Lehmann, J | 1 |
| Bekkers, JM; Stevens, CF | 1 |
| Eysel, UT; FitzGibbon, T; Funke, K | 1 |
| Chandler, SH; Katakura, N | 2 |
| Larson-Prior, LJ; Slater, NT; Ulinski, PS | 1 |
| Akoev, GN; Andrianov, GN; Bromm, B; Szabo, T | 1 |
| Collins, GG | 1 |
| Choi, DW; Goldberg, MP; Kaku, DA | 1 |
| Delrée, P; Lefebvre, PP; Leprince, P; Moonen, G; Rigo, JM; Rogister, B; Weber, T | 1 |
| Hicks, TP; Kaneko, T; Metherate, R; Oka, JI; Stark, CA | 1 |
| Ogawa, T; Takahashi, Y | 1 |
| Cherubini, E; Kilić, G; Moran, O | 1 |
| Glantz, RM; Pfeiffer-Linn, C | 1 |
| Paton, JF; Rogers, WT; Schwaber, JS | 1 |
| Cerne, R; Gerber, G; Randić, M | 1 |
| Frusciante, MJ; Javitt, DC; Nussenzveig, IZ; Sircar, R; Wong, ML; Zukin, SR | 1 |
| Sarafian, T; Torres, M; Verity, MA | 1 |
| Bruce, EN; Jung, R; Katona, PG | 1 |
| Christenson, J; Grillner, S | 1 |
| Chalmers, J; Drolet, G; Mills, E; Minson, J | 1 |
| Benveniste, M; Mayer, ML | 1 |
| Ikonomidou, C; Sieklucka, M; Turski, WA; Urbańska, E | 1 |
| Lipton, P; Lobner, D | 1 |
| Insel, TR; Skolnick, P; Trullas, R; Winslow, JT | 1 |
| Benveniste, M; Mayer, ML; Mienville, JM; Sernagor, E | 1 |
| Okamoto, K; Sakai, Y; Sekiguchi, M | 1 |
| Bradley, PM; Burns, BD; Chinnery, PF; Webb, AC | 1 |
| Miyamoto, T; Okada, Y; Sakurai, T | 1 |
| Baimbridge, KG; Kessler, M; Lynch, G; Oliver, MW; Shacklock, JA | 1 |
| Ashbeck, GA; Tauck, DL | 1 |
| Raigorodsky, G; Urca, G | 1 |
| Feldman, JL; Liu, G; Smith, JC | 1 |
| Buchwald, NA; Cepeda, C; Dudek, FE; Kim, YI; Peacock, WJ; Tasker, JG; Walsh, JP; Wuarin, JP | 1 |
| Horne, AL; Kemp, JA; Woodruff, GN | 1 |
| Dingledine, R; McNamara, D | 1 |
| Boeijinga, PH; Lopes da Silva, FH; Pennartz, CM | 1 |
| Doi, K; Matsunaga, T; Tsumoto, T | 1 |
| Burgoyne, RD; Cambray-Deakin, MA | 1 |
| Chiamulera, C; Costa, S; Reggiani, A | 1 |
| Daló, NL; Piña, JC | 1 |
| Dow, KE; Riopelle, RJ | 1 |
| Dudek, FE; Gribkoff, VK | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Vega, JL | 1 |
| Chandler, SH | 1 |
| Krebs, JC; Trifunovic, R; Wirtshafter, D | 1 |
| Costa, E; Danysz, W; Fadda, E; Wroblewski, JT | 1 |
| Alesiani, M; Cherici, G; Galli, A; Mori, F; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Evans, RH; Long, SK | 1 |
| Davidoff, RA; Hackman, JC; Zhang, DX | 1 |
| Gerber, G; Randić, M | 1 |
| MacDonald, JF; Schneiderman, JH | 1 |
| Laguzzi, R; Le Galloudec, E; Merahi, N | 1 |
| Blessing, WW | 1 |
| Kimura, F; Nishigori, A; Shirokawa, T; Tsumoto, T | 1 |
| Collins, JF; Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Turski, WA | 1 |
| Jahr, CE; Yoshioka, K | 1 |
| Curry, K; Magnuson, DS; McLennan, H; Peet, MJ | 2 |
| Hamberger, A; Jacobson, I | 1 |
| Davies, J; Miller, AJ; Sheardown, MJ | 1 |
| Freeman, JA; Langdon, RB | 1 |
| Brodin, L; Buchanan, JT; Dale, N; Grillner, S | 1 |
| Burgoyne, RD; Cambray-Deakin, MA; Pearce, IA | 1 |
| Barry, MJ; O'Donovan, MJ | 1 |
| Stone, TW | 1 |
| Hagiwara, S; Hirano, T | 1 |
| Salt, TE | 1 |
| Roberts, A; Sillar, KT | 1 |
| Burton, NR; Smith, DA; Stone, TW | 1 |
| Chang, HS; Kano, M; Kato, M | 1 |
| Mayer, ML; Vyklický, L; Westbrook, GL | 1 |
| Trifunovic, R; Wirtshafter, D | 1 |
| Burton, NR; Smith, DA; Stone, TW; Williams, TL | 2 |
| Felder, RB; Miller, BD | 1 |
| Cherubini, E; North, RA; Williams, JT | 1 |
| Chalmers, JP; Mills, EH; Minson, JB; Pilowsky, PM | 1 |
| Choi, DW; Kim, JP | 1 |
| Herrling, PL | 1 |
| Cherubini, E; Herrling, PL; Lanfumey, L; Stanzione, P | 1 |
| Perkins, MN; Stone, TW | 1 |
| Payne, RS; Rigor, BM; Schurr, A | 1 |
| Song, XJ; Zhao, ZQ | 2 |
| Laurie, DJ; Seeburg, PH | 1 |
| Dowling, JE; Grant, GB | 1 |
| Han, D; Ogita, K; Yoneda, Y | 2 |
| Abe, K; Ikegaya, Y; Saito, H | 1 |
| Hatton, GI; Smithson, KG; Yang, QZ | 1 |
| Eki, T; Karp, SJ; Masu, M; Nakanishi, S; Ozawa, K | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Brownstone, RM; Geiger, JD; Knudsen, BE; Magnuson, DS; Nath, A | 1 |
| Mennini, T; Miari, A; Presti, ML; Rizzi, M; Samanin, R; Vezzani, A | 1 |
| Hu, WH; Jen, MF; Li, FC; Sun, XJ | 1 |
| Bading, H; Dudek, H; Greenberg, ME; Lipton, SA; Segal, MM; Sucher, NJ | 1 |
| Ammendola, D; De Sarro, A; De Sarro, G; Nava, F | 1 |
| Chase, MH; López-Rodríguez, F; Morales, FR; Soja, PJ | 1 |
| Croucher, MJ; Patel, DR; Sturt, NJ | 1 |
| Nowak, G; Ordway, GA; Paul, IA | 1 |
| Flores, A; Soto, E; Vega, R | 1 |
| Hirota, A; Kamino, K; Momose-Sato, Y; Sakai, T; Sato, K | 2 |
| Connor, JA; Landis, DM; Mahanty, NK; Pozzo Miller, LD | 1 |
| Jessa, M; Nazar, M; Palejko, W; Plaznik, A | 1 |
| Becquet, D; Deprez, P; Fache, MP; Faudon, M; Giraud, P; Héry, F; Héry, M | 1 |
| D'Hooge, R; De Deyn, PP; Pei, YQ | 1 |
| Sugiyama, M; Takahashi, MP; Tsumoto, T | 1 |
| Cauller, LJ; Connors, BW | 1 |
| Layer, RT; Nowak, G; Paul, IA; Skolnick, P | 1 |
| Eróstegui, C; Flores, A; Soto, E; Vega, R | 1 |
| Oblin, A; Schoemaker, H | 1 |
| Hagevik, A; McClellan, AD | 1 |
| Chazot, PL; Cik, M; Stephenson, FA | 1 |
| Morrisett, RA | 1 |
| Krnjević, K; Zhu, PJ | 1 |
| Bowser-Riley, F; Davies, SN; Shuker, MA | 1 |
| Bousquet, P; Feldman, J; Mettauer, B; Monassier, L; Roegel, JC; Tibiriça, E | 1 |
| Herron, CE; Malenka, RC | 1 |
| Gale, K; Halonen, T; Tortorella, A; Zrebeet, H | 1 |
| Onozuka, M; Watanabe, K | 1 |
| Ball, GF; Wieraszko, A | 1 |
| Ebner, TJ; Elias, SA; Yae, H | 1 |
| Boje, KM; Skolnick, P; Wong, G | 1 |
| Lux, HD; Parsons, CG; Zong, X | 1 |
| Layer, RT; Nowak, G; Paul, IA; Skolnick, P; Trullas, R | 1 |
| Abercrombie, ED; Keefe, KA; Zigmond, MJ | 1 |
| Cattabeni, F; De Graan, PN; Di Luca, M; Gispen, WH; Ramakers, GM; Urban, IJ | 1 |
| Abe, K; Saito, H | 1 |
| Féger, J; Mouroux, M | 1 |
| Gdovin, M; Li, A; Nattie, EE | 1 |
| Giberti, A; Mugnaini, M; Ratti, E; van Amsterdam, FT | 1 |
| Buchwald, NA; Cohen, RW; Levine, MS; Radisavljevic, Z; Siviy, SM; Walsh, JP | 1 |
| Baran, H; Du, F; French, ED; McMaster, OG; Schwarcz, R; Wu, HQ | 1 |
| Brainard, MS; Feldman, DE; Knudsen, EI | 1 |
| Akhondzadeh, S; Stone, TW | 1 |
| London, ED; Matsunaga, T; Mukhin, AG | 1 |
| Gebhart, GF; Kolhekar, R | 1 |
| Gribkoff, VK; Molinoff, PB; Zhong, J | 1 |
| Ennis, M; Shipley, MT; Zimmer, LA | 1 |
| Cull-Candy, SG; Feldmeyer, D; Momiyama, A | 1 |
| Couratier, P; Dussartre, C; Hugon, J; Lesort, M; Terro, F | 1 |
| Chen, K; Godfrey, DA; Waller, HJ | 1 |
| Beninger, RJ; Boegman, RJ; Flesher, S; Jhamandas, KH; Pawley, AC | 1 |
| Bonham, AC; Wilson, CG; Zhang, Z | 1 |
| Attwell, D; Sarantis, M; Takahashi, M | 1 |
| Debler, K; Dieringer, N; Straka, H | 1 |
| Gustafsson, B; Pananceau, M | 1 |
| Arnelle, DR; Choi, YB; D'Emilia, DM; Kim, WK; Kumar, S; Lipton, SA; Rayudu, PV; Stamler, JS | 1 |
| Niu, YP; Wigstrom, H; Xiao, MY | 1 |
| Leslie, SW; Randall, PK; Robichon, R | 1 |
| Leibrock, J; Prücher, H; Rautenberg, W | 1 |
| Fukumori, R; Kubo, T; Yamaguchi, H; Yanagihara, Y | 1 |
| Kawabe, A; Maruoka, Y; Nakamura, M; Ohno, Y; Ohtani, K; Sakamoto, H; Tamamura, C; Tanaka, H; Yasuda, H | 1 |
| Fujimoto, I; Fukuda, A; Hida, H; Muramatsu, K; Nishino, H; Okabe, A; Shimano, Y | 1 |
| Camarasa, J; Camins, A; Escubedo, E; Gabriel, C; Pallàs, M; Sureda, FX | 1 |
| Chai, CY; Kuo, JS; Wang, Y; Wu, WC | 1 |
| Furuta, S | 1 |
| Butcher, KS; Cechetto, DF | 1 |
| Boje, KM; Lakhman, SS | 1 |
| Dong, L; Durham, HD; Figlewicz, DA; Minotti, S; Roy, J | 1 |
| Curry, K; Pajouhesh, H | 1 |
| Abdrachmanova, G; Palecek, JI; Vlachová, V; Vyklick, L | 1 |
| Hinoi, E; Ogita, K; St'astny, F; Yoneda, Y | 1 |
| Bear, MF; Huganir, RL; Philpot, BD; Quinlan, EM | 1 |
| Bongianni, F; Deliagina, TG; Grillner, S | 1 |
| Kullmann, DM; Melyan, Z; Min, MY | 1 |
| Foldes, JK; Hauser, KF; Turbek, CS | 1 |
| Andrew, RD; Jarvis, CR; Obeidat, AS | 1 |
| Ceresoli-Borroni, G; Guidetti, P; Hodgkins, PS; Poeggeler, B; Rassoulpour, A; Schwarcz, R; Wu, HQ | 1 |
| Frankiewicz, T; Parsons, CG; Pilc, A | 1 |
| Hamba, M; Onodera, K; Takahashi, T | 1 |
| Bunney, BS; Shi, WX; Zhang, XX | 1 |
| Gemignani, A; Paudice, P; Pittaluga, A; Raiteri, M | 1 |
| Chu, ZG; Hablitz, JJ; Zhou, FM | 1 |
| Aston-Jones, G; Ivanov, A | 1 |
| Feroah, TR; Forster, HV; Geiger, L; Hodges, M; Martino, P; Pan, LG; Serra, A; Wenninger, JM | 1 |
| Barnabi, F; Cechetto, DF | 1 |
| Begon, S; Dubray, C; Eschalier, A; Mazur, A; Pickering, G; Rayssiguier, Y | 1 |
| Gong, QL; Li, P; Peng, YJ; Wang, N | 1 |
| Goldstein-Daruech, N; Inderkum, A; Pedemonte, M; Velluti, RA | 1 |
| Feroah, TR; Forster, HV; Fuentes, CG; Hodges, M; Martino, P; Pan, L; Rice, T; Wenninger, J | 1 |
| Bakalkin, G; Esashi, A; Kisara, K; Nakagawasai, O; Niijima, F; Sakurada, C; Sakurada, T; Tadano, T; Tan-No, K; Terenius, L | 1 |
| Wu, E | 1 |
| Fogel, R; Zhang, X | 1 |
| Chai, CY; Hong, LZ | 1 |
| Geiger, JD; Hochman, S; Moore, A; Nath, A; Song, L | 1 |
| Ogonowski, AA; Smith, JB | 1 |
| Chen, QH; Haywood, JR; Toney, GM | 1 |
| Albarello, L; Capella, C; Chiaravalli, AM; Dominioni, L; Frigo, G; Giaroni, C; Lecchini, S; Zanetti, E | 1 |
| Inoue, M; Kawamura, Y; Kudo, Y; Manita, S; Miyakawa, H; Nakamura, T | 1 |
| Behr, J; Manahan-Vaughan, D; Solger, J; Wozny, C | 1 |
| Bergeron, R; Krasteniakov, NV; Martina, M | 1 |
| Grundke-Iqbal, I; Haque, N; Iqbal, K; Li, L; Sengupta, A | 1 |
| Buckwalter, JB; Clifford, PS; Mueller, PJ | 1 |
| Concas, A; Marino, G; Minei, R; Pierobon, P; Porcu, P; Sogliano, C; Tino, A; Tortiglione, C | 1 |
| Bongianni, F; Mutolo, D; Nardone, F; Pantaleo, T | 1 |
| Barger, SW; Jiang, S; Sims, TJ; Wu, SZ | 1 |
| Deuchars, J; Deuchars, SA; Milligan, CJ; Stornetta, RL | 1 |
| Qiao, H; Wen, L; Yang, S; Zhang, Y; Zhou, W | 1 |
| Lee, SW; Stanley, BG | 1 |
| Zhou, W; Zhu, H | 1 |
| Chen, HK; Su, CK | 1 |
| Carley, DW; Radulovacki, M; Saponjic, J; Stoiljkovic, M | 1 |
| Li, DP; Pan, HL | 1 |
| Esashi, A; Furuta, S; Nakagawasai, O; Niijima, F; Sato, T; Satoh, S; Tadano, T; Tan-No, K; Yasuhara, H | 1 |
| Sartor, DM; Verberne, AJ | 1 |
| Fukushima, M; Kano, T; Katayama, Y; Koshinaga, M; Suma, T | 1 |
| Jean, A; Lebrun, B; Roux, J; Trouslard, J; Wanaverbecq, N | 1 |
| Eguchi, K; Kanda, T; Takahashi, T; Yamashita, T | 1 |
| Chari, M; Cheung, GW; Kokorovic, A; Lai, TY; Lam, CK; Lam, TK; Su, BB; Wang, PY; Yang, CS | 1 |
| Bao, J; Huang, CH; Sakaba, T | 1 |
| Borroni, P; Crema, F; Frigo, G; Giaroni, C; Giuliani, D; Lecchini, S; Marchet, S; Moro, E; Oldrini, R; Trinchera, M; Zanetti, E | 1 |
| Brüning, CA; Nogueira, CW; Prigol, M; Zeni, G | 1 |
| Carter, JR; Chapp, AD; Chen, QH; Gui, L; Huber, MJ; Larson, RA; Liu, J; Zhu, J | 1 |
| Dubach, MF; Dybdal, D; Forcelli, PA; Gale, K; Malkova, L; Wellman, LL | 1 |
| Aguilera, P; Montes de Oca Balderas, P | 1 |
| Acton, D; Miles, GB | 1 |
| Destreel, G; Engel, D; Seutin, V | 1 |
257 other study(ies) available for kynurenic acid and 2-amino-5-phosphonovalerate
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Suppression of a calcium current by CNQX and kynurenate.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Calcium Channel Blockers; Cells, Cultured; Electrophysiology; Excitatory Amino Acid Antagonists; Ibotenic Acid; Ictaluridae; Kynurenic Acid; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina | 1992 |
Administration of excitatory amino acid antagonists via microdialysis attenuates the increase in glucose utilization seen following concussive brain injury.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Brain Concussion; Dialysis; Energy Metabolism; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Ions; Kynurenic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Glutamate stimulation of tyrosine hydroxylase is mediated by NMDA receptors in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atropine; Corpus Striatum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Kynurenic Acid; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tyrosine 3-Monooxygenase | 1992 |
In vivo modulation of N-methyl-D-aspartate receptor-dependent long-term potentiation by the glycine modulatory site.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; Kynurenic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Synapses | 1992 |
mRNA coding for neurotransmitter receptors in a human astrocytoma.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aged; Animals; Astrocytoma; Brain Neoplasms; Calcium Channels; Cell Line; Culture Techniques; Female; Glutamates; Humans; Kainic Acid; Kynurenic Acid; Male; Membrane Potentials; Oocytes; Pirenzepine; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus | 1992 |
Hypothalamic excitatory amino acid receptors mediate stress-induced tachycardia in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Heart Rate; Hypothalamus, Middle; Kynurenic Acid; Male; Microinjections; Motor Activity; Neurotoxins; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Stress, Physiological | 1992 |
Long-term potentiation in slices of kitten visual cortex and the effects of NMDA receptor blockade.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bicuculline; Cats; Electric Stimulation; Evoked Potentials; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Regression Analysis; Visual Cortex | 1992 |
Spontaneous firing level distinguishes the effects of NMDA and non-NMDA receptor antagonists on the ganglion cells in the cat retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cats; Dizocilpine Maleate; Evoked Potentials, Visual; Ganglia; Iontophoresis; Kynurenic Acid; Piperazines; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Retina | 1992 |
Evidence that non-NMDA receptors are involved in the excitatory pathway from the pedunculopontine region to nigrostriatal dopaminergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Evoked Potentials; Glutamine; Iontophoresis; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Pons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses | 1992 |
L-homocysteic acid selectively activates N-methyl-D-aspartate receptors of rat retinal ganglion cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Glycine; Homocysteine; Kynurenic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Stimulation, Chemical | 1992 |
Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; Chromosome Deletion; Cloning, Molecular; Dizocilpine Maleate; DNA; Gene Library; Kynurenic Acid; Molecular Sequence Data; N-Methylaspartate; Oocytes; Piperazines; Prosencephalon; Rats; Receptors, N-Methyl-D-Aspartate; Restriction Mapping; RNA Splicing; RNA, Messenger; Xenopus | 1992 |
Role of NMDA receptors in hypothalamic facilitation of feline defensive rage elicited from the midbrain periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Atropine; Cats; Female; Hypothalamus, Middle; Immunohistochemistry; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Neurotransmitter Agents; Periaqueductal Gray; Quinoxalines; Rage; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1992 |
Glutamate antagonists applied to midbody spinal cord segments reduce the excitability of the fictive rostral scratch reflex in the turtle.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord; Thorax; Turtles | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Lateral hypothalamus and local stimulation induced postsynaptic responses in zona incerta neurons in an in vitro slice preparation of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Evoked Potentials; Hypothalamic Area, Lateral; In Vitro Techniques; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurons; Periaqueductal Gray; Piperazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses | 1992 |
Excitatory amino acid receptors appear to mediate paroxysmal depolarizing shifts in rat neocortical neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Frontal Lobe; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; Motor Cortex; Neurons; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1992 |
In vitro and in vivo characterization of the NMDA receptor-linked strychnine-insensitive glycine site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Strychnine | 1992 |
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
Analysis of synaptic events in the mouse accessory olfactory bulb with current source-density techniques.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Electric Stimulation; Evoked Potentials; Female; Kynurenic Acid; Mice; Mice, Inbred BALB C; Nasal Septum; Olfactory Bulb; Receptors, Amino Acid; Synapses; Synaptic Transmission | 1992 |
Control of 40-Hz firing of reticular thalamic cells by neurotransmitters.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Bicuculline; Electric Conductivity; Female; gamma-Aminobutyric Acid; Ketanserin; Kynurenic Acid; Male; Neurons; Neurotransmitter Agents; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reticular Formation; Scopolamine; Thalamic Nuclei | 1992 |
NMDA receptor mediates dopamine release in the striatum of unanesthetized rats as measured by brain microdialysis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atropine; Brain Chemistry; Corpus Striatum; Dialysis; Dopamine; Glycine; Kynurenic Acid; Magnesium; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1992 |
[Role of glutamate intracortical connections in conditioned reflex activity].
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Cerebral Cortex; Conditioning, Classical; Evoked Potentials, Somatosensory; Glutamates; Glutamic Acid; Iontophoresis; Ketamine; Kynurenic Acid; Membrane Potentials; Neurons; Receptors, N-Methyl-D-Aspartate | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Shunting of excitatory input to dentate gyrus granule cells by a depolarizing GABAA receptor-mediated postsynaptic conductance.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Chlorides; Electrodes; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Interneurons; Ion Channels; Kynurenic Acid; Male; Membrane Potentials; Neural Conduction; Neuromuscular Junction; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1992 |
Pharmacological properties of N-methyl-D-aspartate receptors on ganglion cells of an amphibian retina.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Electrodes; In Vitro Techniques; Ion Channels; Kynurenic Acid; Magnesium; Perfusion; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Tetrodotoxin; Zinc | 1992 |
NMDA receptor agonists selectively block N-type calcium channels in hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Aspartic Acid; Calcium; Calcium Channels; Glutamates; Hippocampus; Kynurenic Acid; Mollusk Venoms; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1991 |
Glutamate receptor subtypes mediate excitatory synaptic currents of dopamine neurons in midbrain slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dopamine; Evoked Potentials; Glutamates; In Vitro Techniques; Kynurenic Acid; Mecamylamine; Mesencephalon; Neurons; Picrotoxin; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
Ipsilateral but not contralateral blockade of excitatory amino acid receptors in the caudal ventrolateral medulla inhibits aortic baroreceptor reflex in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aorta; Blood Pressure; Dizocilpine Maleate; Electric Stimulation; Glutamates; Glutamic Acid; Heart Rate; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Muscimol; N-Methylaspartate; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Reflex; Synaptic Transmission | 1991 |
Excitatory amino acid antagonists inhibit synaptic responses in the guinea pig hypothalamic paraventricular nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Kynurenic Acid; Male; Paraventricular Hypothalamic Nucleus; Quinoxalines; Synapses | 1991 |
NMDA receptor complex antagonists have potential anxiolytic effects as measured with separation-induced ultrasonic vocalizations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety, Separation; Behavior, Animal; Buspirone; Diazepam; Dioxins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Indoles; Kynurenic Acid; Maternal Deprivation; Mephenesin; Piperidines; Quinolizines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Antagonists; Spiro Compounds; Valine; Vocalization, Animal | 1991 |
Dorsal root potentials in the isolated frog spinal cord: amino acid neurotransmitters and magnesium ions.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kynurenic Acid; Magnesium; Neurons, Afferent; Picrotoxin; Potassium; Potassium Channels; Quinoxalines; Rana pipiens; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Nerve Roots; Synaptic Transmission | 1991 |
Neurotransmitter release from hair cells and its blockade by glutamate-receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Animals; Cobalt; Dipeptides; Electrophysiology; Glutamates; Goldfish; Hair Cells, Auditory; Kynurenic Acid; Neurotransmitter Agents; Poisson Distribution; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
Regulation of CCK release in cerebral cortex by N-methyl-D-aspartate receptors: sensitivity to APV, MK-801, kynurenate, magnesium and zinc ions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Dizocilpine Maleate; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Potassium; Quisqualic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Sincalide; Zinc | 1991 |
A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effects on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Diseases; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats | 1991 |
Glutamate and glycine co-activate while polyamines merely modulate the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Biguanides; Binding, Competitive; Biogenic Polyamines; Biotransformation; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1991 |
Interaction of hypothalamic GABAA and excitatory amino acid receptors controlling heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kynurenic Acid; Male; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1991 |
Excitatory and inhibitory autaptic currents in isolated hippocampal neurons maintained in cell culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium Chloride; Cells, Cultured; Electric Conductivity; Electric Stimulation; Electrophysiology; Glycine; Hippocampus; Kynurenic Acid; Magnesium Chloride; Membrane Potentials; Neuroglia; Neurons; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Strychnine | 1991 |
Retinogeniculate transmission by NMDA and non-NMDA receptors in the cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Geniculate Bodies; Glutamates; Glutamic Acid; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Photic Stimulation; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Synaptic Transmission | 1991 |
Iontophoretic analysis of the pharmacologic mechanisms responsible for initiation and modulation of trigeminal motoneuronal discharge evoked by intra-oral afferent stimulation.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Clonidine; Dental Pulp; Evoked Potentials; Guinea Pigs; Kynurenic Acid; Male; Motor Neurons; Mouth Mucosa; Neck Muscles; Nerve Fibers; Norepinephrine; Phenylephrine; Prazosin; Synapses; Synaptic Transmission; Tongue; Trigeminal Nerve; Yohimbine | 1991 |
Excitatory amino acid receptor-mediated transmission in geniculocortical and intracortical pathways within visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cerebral Cortex; Electric Stimulation; Geniculate Bodies; Kynurenic Acid; Neural Pathways; Neurons; Quinoxalines; Receptors, Amino Acid; Receptors, Cell Surface; Synaptic Transmission; Turtles; Visual Cortex | 1991 |
Effects of excitatory amino acid antagonists on synaptic transmission in the ampullae of Lorenzini of the skate Raja clavata.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Aminobutyrates; Animals; Dipeptides; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Kynurenic Acid; Pipecolic Acids; Psychotropic Drugs; Receptors, N-Methyl-D-Aspartate; Skates, Fish; Synapses; Synaptic Transmission | 1991 |
Pharmacological evidence that NMDA receptors contribute to mono- and di-synaptic potentials in slices of mouse olfactory cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; Mice; N-Methylaspartate; Olfactory Bulb; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Synapses | 1991 |
Antagonism of non-NMDA receptors augments the neuroprotective effect of NMDA receptor blockade in cortical cultures subjected to prolonged deprivation of oxygen and glucose.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Culture Media; Dizocilpine Maleate; Fetus; Glucose; Kynurenic Acid; Mice; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Kainate and NMDA toxicity for cultured developing and adult rat spiral ganglion neurons: further evidence for a glutamatergic excitatory neurotransmission at the inner hair cell synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cochlea; Ganglia; Glutamates; Glutamic Acid; Hair Cells, Auditory, Inner; Immunohistochemistry; In Vitro Techniques; Indicators and Reagents; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Neurons, Afferent; Organ of Corti; Quisqualic Acid; Rats; Rats, Inbred Strains; Synaptic Transmission | 1991 |
Amino acids as transmitters of synaptic excitation in neocortical sensory processes.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Calcium; Cats; Cerebral Cortex; Chromatography, High Pressure Liquid; Electric Stimulation; Electrodes; Female; Iontophoresis; Kynurenic Acid; Magnesium; Male; Neural Pathways; Neurons, Afferent; Neurotransmitter Agents; Quinoxalines; Somatosensory Cortex; Synapses; Thalamus | 1991 |
Composition of the excitatory postsynaptic potentials recorded from rat visual cortical neurons in layer. II/III: An in vitro electrophysiological and pharmacological studies.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Kynurenic Acid; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Visual Cortex | 1991 |
N-methyl-D-aspartate receptor-mediated spontaneous activity in cerebellar granule cells in culture.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium Channels; Cells, Cultured; Cerebellum; Cobalt; Dizocilpine Maleate; Glutamates; Glutamic Acid; Kynurenic Acid; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1991 |
An arthropod NMDA receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Astacoidea; Cesium; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Immunoenzyme Techniques; Interneurons; Kynurenic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Vision, Ocular | 1991 |
The ventrolateral medulla as a source of synaptic drive to rhythmically firing neurons in the cardiovascular nucleus tractus solitarius of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Stem; Cardiovascular System; Electric Stimulation; Evoked Potentials; Functional Laterality; In Vitro Techniques; Kynurenic Acid; Medulla Oblongata; Membrane Potentials; Neurons; Rats; Rats, Inbred Strains; Synapses | 1991 |
Participation of excitatory amino acid receptors in the slow excitatory synaptic transmission in rat spinal dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Neurotransmitter Agents; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Polyamine effects upon N-methyl-D-aspartate receptor functioning: differential alteration by glutamate and glycine site antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Kinetics; Kynurenic Acid; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermidine | 1991 |
Paradoxical potentiation by low extracellular Ca2+ of acute chemical anoxic neuronal injury in cerebellar granule cell culture.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebellum; Choline; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Glutamates; Glutamic Acid; Glutathione; Iodoacetates; Iodoacetic Acid; Kynurenic Acid; Meglumine; Nerve Tissue Proteins; Neurons; Neurotoxins; Potassium; Potassium Cyanide; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium; Stimulation, Chemical | 1991 |
Cardiorespiratory responses to glutamatergic antagonists in the caudal ventrolateral medulla of rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Hemodynamics; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Neurons; Pressoreceptors; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Respiration | 1991 |
Primary afferents evoke excitatory amino acid receptor-mediated EPSPs that are modulated by presynaptic GABAB receptors in lamprey.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Ibotenic Acid; Interneurons; Kynurenic Acid; Lampreys; Mechanoreceptors; N-Methylaspartate; Quinoxalines; Receptors, GABA-A; Receptors, Neurotransmitter; Skin; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Effect of intrathecal amino acid receptor antagonists on basal blood pressure and pressor responses to brainstem stimulation in normotensive and hypertensive rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Blood Pressure; Brain Stem; Cerebrovascular Disorders; Electric Stimulation; Heart Rate; Hypertension; Kynurenic Acid; Methysergide; Neural Pathways; Neurotransmitter Agents; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord | 1990 |
Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding Sites; Biophysical Phenomena; Biophysics; Cells, Cultured; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ion Channels; Kinetics; Kynurenic Acid; Models, Neurological; Piperazines; Receptors, N-Methyl-D-Aspartate | 1991 |
Aminooxyacetic acid produces excitotoxic lesions in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminooxyacetic Acid; Animals; Behavior, Animal; Catalepsy; Caudate Nucleus; Corpus Striatum; Female; Glutamate Decarboxylase; Kynurenic Acid; Male; Microinjections; Microscopy, Electron; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Sigma-ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cyclazocine; Dizocilpine Maleate; Glutamates; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Ketamine; Kynurenic Acid; Male; Models, Neurological; Phencyclidine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, sigma | 1990 |
Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Female; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Social Isolation; Vocalization, Animal | 1990 |
An iontophoretic analysis of the pharmacologic mechanisms responsible for trigeminal motoneuronal discharge during masticatory-like activity in the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Guinea Pigs; Iontophoresis; Jaw; Kynurenic Acid; Male; Mastication; Motor Neurons; Movement; Neck Muscles; Norepinephrine; Serotonin; Synapses; Synaptic Transmission; Trigeminal Nerve | 1990 |
Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Aspartic Acid; Cells, Cultured; Glycine; Hippocampus; Kynurenic Acid; Mice; N-Methylaspartate; Neurons; Osmolar Concentration; Piperazines | 1990 |
Glycine-insensitive NMDA-sensitive receptor expressed in Xenopus oocytes by guinea pig cerebellar mRNA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cerebellum; Electric Conductivity; Female; Glycine; Guinea Pigs; Kynurenic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Phencyclidine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1990 |
Local circuitry in the IMHV of the domestic chick (Gallus domesticus).
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Brain; Calcium; Chickens; Corpus Striatum; Electric Stimulation; Kynurenic Acid; Magnesium; Models, Neurological; Neurons; Synapses | 1990 |
Masking effect of NMDA receptor antagonists on the formation of long-term potentiation (LTP) in superior colliculus slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Denervation; Dibenzocycloheptenes; Dipeptides; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Magnesium; Mice; Nerve Degeneration; Optic Nerve; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Visual Cortex | 1990 |
The glycine site modulates NMDA-mediated changes of intracellular free calcium in cultures of hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cells, Cultured; Embryo, Mammalian; Glycine; Hippocampus; Ketamine; Kinetics; Kynurenic Acid; Macromolecular Substances; N-Methylaspartate; Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Glycine synergistically potentiates the enhancement of LTP induced by a sulfhydryl reducing agent.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dithiothreitol; Drug Synergism; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1990 |
Spinal antinociceptive effects of excitatory amino acid antagonists: quisqualate modulates the action of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesics; Animals; Aspartic Acid; Dipeptides; Electric Stimulation; Glutamine; Kynurenic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Vocalization, Animal | 1990 |
Excitatory amino acid-mediated transmission of inspiratory drive to phrenic motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Brain Stem; In Vitro Techniques; Inhalation; Kynurenic Acid; Motor Neurons; Phrenic Nerve; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1990 |
Synaptic transmission in human neocortex removed for treatment of intractable epilepsy in children.
Topics: 2-Amino-5-phosphonovalerate; Adolescent; Bicuculline; Child; Child, Preschool; Epilepsy; Female; GABA Antagonists; Humans; Infant; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Psychosurgery; Pyramidal Tracts; Spasms, Infantile; Synapses; Synaptic Transmission | 1990 |
Synaptic potentials mediated by excitatory amino acid receptors in the nucleus accumbens of the rat, in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Sulpiride; Synapses | 1990 |
Dual effect of glycine on NMDA-induced neurotoxicity in rat cortical cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebral Cortex; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Kynurenic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Degeneration; Neurons; Oocytes; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Taurine; Xenopus | 1990 |
Locally evoked potentials in slices of the rat nucleus accumbens: NMDA and non-NMDA receptor mediated components and modulation by GABA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Axons; Dipeptides; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Kynurenic Acid; Male; Neurons; Neurotoxins; Nucleus Accumbens; Pentobarbital; Picrotoxin; Pyridostigmine Bromide; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin; Time Factors; Tubocurarine | 1990 |
Actions of excitatory amino acid antagonists on synaptic inputs to the rat medial vestibular nucleus: an electrophysiological study in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain Stem; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; In Vitro Techniques; Kynurenic Acid; Male; Neural Pathways; Neurons, Afferent; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Valine; Vestibular Nuclei | 1990 |
Regulation of neurite outgrowth from cerebellar granule cells in culture: NMDA receptors and protein kinase C.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Cerebellum; Cytosol; Kynurenic Acid; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems | 1990 |
Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Injections, Intraventricular; Kynurenic Acid; Learning; Male; Mice; N-Methylaspartate; Piperazines; Receptors, Glycine; Receptors, Neurotransmitter; Seizures; Strychnine | 1990 |
Kynurenate and 2-amino-5-phosphonovalerate alter the spinal seizures evoked by sudden cooling of toad isolated cords.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bufo marinus; Cold Temperature; Kynurenic Acid; Muscle Contraction; Seizures; Spinal Cord | 1990 |
Ethanol inhibits NMDA-stimulated neurite growth by sensory neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Chick Embryo; Ethanol; Ganglia, Spinal; Glycine; Kynurenic Acid; Magnesium; N-Methylaspartate; Neurites; Neurons, Afferent | 1990 |
Effects of excitatory amino acid antagonists on synaptic responses of supraoptic neurons in slices of rat hypothalamus.
Topics: Animals; Bicuculline; Dipeptides; Female; In Vitro Techniques; Kynurenic Acid; Male; Membrane Potentials; Neurons; Rats; Supraoptic Nucleus; Synapses; Valine | 1990 |
Excitatory transmitters, ventral root potentials and [K+]o in the isolated frog leg-spinal cord preparation.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; In Vitro Techniques; Kynurenic Acid; Pain; Physical Stimulation; Potassium; Rana pipiens; Spinal Nerve Roots; Substance P; Valine | 1988 |
Evidence for excitatory amino acid transmission between mesencephalic nucleus of V afferents and jaw-closer motoneurons in the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Guinea Pigs; Kynurenic Acid; Male; Masseter Muscle; Mesencephalon; Motor Neurons; N-Methylaspartate; Neurotransmitter Agents; Synapses; Synaptic Transmission; Trigeminal Nuclei; Valine | 1989 |
Behavioral and biochemical evidence for a functional role of excitatory amino acids in the median raphe nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Dopamine; Dose-Response Relationship, Drug; Kynurenic Acid; Male; Motor Activity; Raphe Nuclei; Rats; Rats, Inbred Strains; Valine | 1989 |
Kynurenate and 2-amino-5-phosphonovalerate interact with multiple binding sites of the N-methyl-D-aspartate-sensitive glutamate receptor domain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding Sites; Binding, Competitive; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Kynurenic Acid; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine; Subcellular Fractions; Valine | 1989 |
Glycine and kynurenate modulate the glutamate receptors in the myenteric plexus and in cortical membranes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Cerebral Cortex; Glycine; Guinea Pigs; In Vitro Techniques; Kynurenic Acid; Myenteric Plexus; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Primary afferent depolarization in the rat spinal cord is mediated by pathways utilising NMDA and non-NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Ganglia, Spinal; In Vitro Techniques; Kynurenic Acid; Neurons, Afferent; Quinoxalines; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
NMDA antagonists and potentiation of NMDA-induced motoneuron depolarizations in the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Evoked Potentials; Ketamine; Kynurenic Acid; Magnesium; Motor Neurons; N-Methylaspartate; Potassium; Rana pipiens; Spinal Cord; Valine | 1989 |
Excitatory amino acid-mediated components of synaptically evoked input from dorsal roots to deep dorsal horn neurons in the rat spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; In Vitro Techniques; Kynurenic Acid; Magnesium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Nerve Roots | 1989 |
Excitatory amino acid blockers differentially affect bursting of in vitro hippocampal neurons in two pharmacological models of epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Ketamine; Kynurenic Acid; Phencyclidine; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Cardiovascular changes induced by the local application of glutamate-related drugs in the rat nucleus tractus solitarii.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Glutamates; Glutamic Acid; Heart Rate; Kynurenic Acid; Male; Medulla Oblongata; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Baroreceptor-vasomotor reflex after N-methyl-D-aspartate receptor blockade in rabbit caudal ventrolateral medulla.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aorta; Blood Pressure; Electric Stimulation; Kidney; Kynurenic Acid; Medulla Oblongata; Pressoreceptors; Rabbits; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Sympathetic Nervous System | 1989 |
Actions of excitatory amino acid antagonists on synaptic potentials of layer II/III neurons of the cat's visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Evoked Potentials, Visual; In Vitro Techniques; Kynurenic Acid; Reaction Time; Receptors, Amino Acid; Receptors, Cell Surface; Visual Cortex | 1989 |
Muscle relaxant action of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Female; Glutamates; Kynurenic Acid; Male; Muscle Relaxants, Central; Muscle Spasticity; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1985 |
Ia afferent excitation of motoneurones in the in vitro new-born rat spinal cord is selectively antagonized by kynurenate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Animals, Newborn; Carbachol; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Male; Motor Neurons; Muscle Spindles; Neurons, Afferent; Rats; Spinal Cord; Spinal Nerve Roots; Strychnine; Synapses; Valine | 1986 |
Ca2+-dependent depolarization and burst firing of rat CA1 pyramidal neurones induced by N-methyl-D-aspartic acid and quinolinic acid: antagonism by 2-amino-5-phosphonovaleric and kynurenic acids.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Calcium; Convulsants; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Valine | 1986 |
Effects of kynurenic acid on evoked extracellular field potentials in the rat olfactory bulb in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Kynurenic Acid; Male; Olfactory Bulb; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Valine | 1986 |
Amino acid receptor mediated excitatory synaptic transmission in the cat red nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Cats; Dipeptides; Female; Glutamates; Glutamine; Kynurenic Acid; Male; Neurons; Piperazines; Receptors, Amino Acid; Receptors, Cell Surface; Red Nucleus; Synapses; Synaptic Transmission; Time Factors; Valine | 1986 |
Antagonists of glutaminergic neurotransmission block retinotectal transmission in goldfish.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cyprinidae; Dipeptides; Excitatory Amino Acid Antagonists; Glutamic Acid; Goldfish; In Vitro Techniques; Kynurenic Acid; Pipecolic Acids; Retina; Superior Colliculi; Synaptic Transmission; Time Factors; Valine | 1986 |
Reticulospinal neurones activate excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Kynurenic Acid; Lampreys; Membrane Potentials; Motor Neurons; Pipecolic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Reticular Formation; Spinal Cord; Valine | 1987 |
Glutamate acting on NMDA receptors stimulates neurite outgrowth from cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Cerebellum; Glutamates; Kynurenic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
The effects of excitatory amino acids and their antagonists on the generation of motor activity in the isolated chick spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Chick Embryo; Convulsants; Dipeptides; In Vitro Techniques; Kynurenic Acid; Motor Activity; Motor Neurons; N-Methylaspartate; Spinal Cord; Valine | 1987 |
Comparison of kynurenic acid and 2-APV suppression of epileptiform activity in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Electrophysiology; Epilepsy; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Osmolar Concentration; Rats; Valine | 1988 |
Synaptic transmission between rat cerebellar granule and Purkinje cells in dissociated cell culture: effects of excitatory-amino acid transmitter antagonists.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Aspartic Acid; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Purkinje Cells; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Tetrodotoxin; Valine | 1988 |
Excitatory amino acid receptors and synaptic transmission in the rat ventrobasal thalamus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Female; Glutamates; Glutamine; Hair; Kynurenic Acid; Male; Neurons; Neurons, Afferent; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Synapses; Synaptic Transmission; Thalamus; Valine; Vibrissae | 1987 |
Unmyelinated cutaneous afferent neurons activate two types of excitatory amino acid receptor in the spinal cord of Xenopus laevis embryos.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Kynurenic Acid; Magnesium; Neurons, Afferent; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Skin; Spinal Cord; Valine; Xenopus laevis | 1988 |
A quantitative pharmacological analysis of some excitatory amino acid receptors in the mouse neocortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Male; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1988 |
The glutamate receptor subtype mediating parallel fibre-Purkinje cell transmission in rabbit cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellar Cortex; Dipeptides; Glutamates; Kynurenic Acid; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rabbits; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1988 |
Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Cations, Divalent; Cells, Cultured; Glycine; Hippocampus; Ketamine; Kynurenic Acid; Magnesium; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Zinc | 1988 |
Stimulation of ingestive behaviors following injections of excitatory amino acid antagonists into the median raphe nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Catheterization; Drinking; Eating; Injections; Kynurenic Acid; Male; Raphe Nuclei; Rats; Rats, Inbred Strains; Valine | 1988 |
Kynurenic acid and AP5 distinguish between NMDA receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Ibotenic Acid; Kynurenic Acid; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Amino acid pharmacology in neocortical slices: evidence for bimolecular actions from an extension of the Hill and Gaddum-Schild equations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kynurenic Acid; Mathematics; Mice; N-Methylaspartate; Pyridines; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Excitatory amino acid receptors intrinsic to synaptic transmission in nucleus tractus solitarii.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Functional Laterality; Glutamates; In Vitro Techniques; Kynurenic Acid; Male; Medulla Oblongata; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Reference Values; Synapses; Synaptic Transmission; Valine | 1988 |
Structural requirements for activation of excitatory amino acid receptors in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; In Vitro Techniques; Kynurenic Acid; Male; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Valine | 1988 |
Synaptic potentials in rat locus coeruleus neurones.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kynurenic Acid; Locus Coeruleus; Neuromuscular Depolarizing Agents; Neurons; Rats; Synapses; Time Factors; Valine | 1988 |
N-methyl-D-aspartate receptors in the spinal cord mediate pressor responses to stimulation of the rostral ventrolateral medulla in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Dipeptides; Electric Stimulation; Glutamates; Heart Rate; Injections, Spinal; Kynurenic Acid; Male; Medulla Oblongata; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Quinolinate neurotoxicity in cortical cell culture.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Kynurenic Acid; L-Lactate Dehydrogenase; Mice; Neuroglia; Pyridines; Quinolinic Acid; Quinolinic Acids | 1987 |
Pharmacology of the corticocaudate excitatory postsynaptic potential in the cat: evidence for its mediation by quisqualate- or kainate-receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cats; Caudate Nucleus; Cerebral Cortex; Evoked Potentials; Female; Kynurenic Acid; Male; Neural Pathways; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, Neurotransmitter; Synaptic Transmission | 1985 |
Excitatory amino acids in synaptic excitation of rat striatal neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Glutamates; Glutamine; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Synapses | 1988 |
In vivo release of [3H]-purines by quinolinic acid and related compounds.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Kynurenic Acid; Male; N-Methylaspartate; Purines; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Tritium | 1983 |
Protection by MK-801 against hypoxia-, excitotoxin-, and depolarization-induced neuronal damage in vitro.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anti-Anxiety Agents; Benzodiazepines; Diltiazem; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Neurons; Nifedipine; Pipecolic Acids; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1995 |
Interaction between substance P and excitatory amino acid receptors in modulation of nociceptive responses of cat spinal dorsal horn neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Electric Stimulation; Homocysteine; Ketamine; Kynurenic Acid; Muscles; Neurokinin-1 Receptor Antagonists; Neurons; Nociceptors; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P; Sural Nerve | 1994 |
Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Cloning, Molecular; Dizocilpine Maleate; DNA; Glutamic Acid; Ion Channels; Kinetics; Kynurenic Acid; Ligands; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins | 1994 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Potentiation by calcium ions of [3H]MK-801 binding to an ion channel associated with the N-methyl-D-aspartate receptor complex in rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Dizocilpine Maleate; Ion Channels; Kynurenic Acid; Male; Phospholipases; Phospholipases A; Protein Binding; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1995 |
Amygdala N-methyl-D-aspartate receptors participate in the induction of long-term potentiation in the dentate gyrus in vivo.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Kynurenic Acid; Long-Term Potentiation; Male; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
NMDA and non-NMDA receptors on rat supraoptic nucleus neurons activated monosynaptically by olfactory afferents.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Female; Kynurenic Acid; Male; Neurons; Neurons, Afferent; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus; Synapses | 1995 |
Molecular cloning and chromosomal localization of the key subunit of the human N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; Brain; Chromosome Mapping; Chromosomes, Human, Pair 9; Cricetinae; Dizocilpine Maleate; DNA; Humans; Hybrid Cells; Karyotyping; Kynurenic Acid; Macromolecular Substances; Magnesium; Molecular Sequence Data; N-Methylaspartate; Oocytes; Poly A; Receptors, N-Methyl-D-Aspartate; RNA; RNA, Messenger; Temporal Lobe; Xenopus; Zinc | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.
Topics: 2-Amino-5-phosphonovalerate; AIDS Dementia Complex; Animals; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Electrophysiology; Fetus; Gene Products, tat; Hippocampus; HIV-1; Humans; Kynurenic Acid; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; tat Gene Products, Human Immunodeficiency Virus; Tetrodotoxin | 1995 |
Adaptive changes in the NMDA receptor complex in rat hippocampus after chronic treatment with CGP 39551.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Kynurenic Acid; Male; Norepinephrine; Phencyclidine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
[Intrathecal co-administration of kappa opioid receptor agonists and NMDA receptor antagonists induces synergistic analgesia in rats].
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Drug Synergism; Dynorphins; Injections, Spinal; Kynurenic Acid; Pain Threshold; Peptide Fragments; Pyrrolidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa | 1994 |
N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blotting, Northern; Calcium; Cells, Cultured; Electrophysiology; Gene Expression Regulation; Genes, fos; Genes, jun; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Hippocampus; Immunohistochemistry; Kainic Acid; Kynurenic Acid; Neurons; Nifedipine; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1995 |
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acids; Glutamine; Imipenem; Kynurenic Acid; Mice; Mice, Inbred DBA; Muscimol; Piperazines; Piperidines; Quinoxalines; Seizures | 1995 |
Effects of excitatory amino acid antagonists on the phasic depolarizing events that occur in lumbar motoneurons during REM periods of active sleep.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Electrooculography; Evoked Potentials; Excitatory Amino Acid Antagonists; Kynurenic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Sciatic Nerve; Sleep, REM; Spinal Cord; Synaptic Transmission | 1995 |
Modulation of D-[2,3 3H]aspartate release from rat forebrain slices by non-NMDA receptor agonists and antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Kynurenic Acid; Male; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Tritium | 1995 |
Alterations in the N-methyl-D-aspartate (NMDA) receptor complex in the frontal cortex of suicide victims.
Topics: 2-Amino-5-phosphonovalerate; Adult; Dizocilpine Maleate; Female; Frontal Lobe; Humans; In Vitro Techniques; Kynurenic Acid; Male; Middle Aged; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Suicide | 1995 |
NMDA-mediated potentiation of the afferent synapse in the inner ear.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Amplifiers, Electronic; Animals; Dizocilpine Maleate; Electrophysiology; Glycine; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons, Afferent; Physical Stimulation; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Synapses; Vestibule, Labyrinth | 1994 |
Responses to glossopharyngeal stimulus in the early embryonic chick brainstem: spatiotemporal patterns in three dimensions from repeated multiple-site optical recording of electrical activity.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Brain Mapping; Brain Stem; Cations; Chick Embryo; Coloring Agents; Electric Stimulation; Electrochemistry; Glossopharyngeal Nerve; Image Processing, Computer-Assisted; Kynurenic Acid; Microscopy; Motor Neurons; Neurons, Afferent; Photometry; Rhodanine; Solitary Nucleus; Specimen Handling; Thiazolidines; Vagus Nerve; Videotape Recording | 1995 |
Spontaneous pyramidal cell death in organotypic slice cultures from rat hippocampus is prevented by glutamate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Death; Culture Techniques; Excitatory Amino Acid Antagonists; Hippocampus; Kynurenic Acid; Magnesium; Nerve Degeneration; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 1994 |
Effects of antagonists at the NMDA receptor complex in two models of anxiety.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Behavior, Animal; Conflict, Psychological; Diazepam; Dizocilpine Maleate; Drinking; Electroshock; Exploratory Behavior; Injections, Intraventricular; Kynurenic Acid; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1994 |
N-methyl-D-aspartic acid/glycine interactions on the control of 5-hydroxytryptamine release in raphe primary cultures.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Gestational Age; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Pregnancy; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Serotonin; Strychnine; Valine | 1993 |
N-methyl-D-aspartate receptors contribute to guanidinosuccinate-induced convulsions in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Drug Interactions; Female; Glutamates; Glutamic Acid; Guanidines; Kainic Acid; Ketamine; Kynurenic Acid; Male; Mice; Receptors, N-Methyl-D-Aspartate; Seizures; Succinates | 1993 |
Contribution of NMDA receptors to tetanus-induced increase in postsynaptic Ca2+ in visual cortex of young rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channel Blockers; Electric Stimulation; Evoked Potentials; Female; Fluorescent Dyes; Heterocyclic Compounds, 3-Ring; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Male; Microscopy, Fluorescence; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spectrometry, Fluorescence; Synapses; Visual Cortex | 1993 |
Synaptic physiology of horizontal afferents to layer I in slices of rat SI neocortex.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Kynurenic Acid; Male; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Synapses; Synaptic Transmission | 1994 |
Adaptation of the NMDA receptor in rat cortex following chronic electroconvulsive shock or imipramine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Electroshock; Glycine; Imipramine; In Vitro Techniques; Kynurenic Acid; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Evidence for NMDA receptor in the afferent synaptic transmission of the vestibular system.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Animals; Glycine; Hair Cells, Auditory; In Vitro Techniques; Kynurenic Acid; Magnesium; N-Methylaspartate; Nerve Fibers; Neurons, Afferent; Receptors, N-Methyl-D-Aspartate; Semicircular Canals; Synapses; Synaptic Transmission; Vestibule, Labyrinth | 1994 |
Complex allosteric modulation of the binding of the NMDA receptor antagonist [3H]CGP39653.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Biguanides; Binding Sites; Glycine; In Vitro Techniques; Kynurenic Acid; Male; Piperidines; Prosencephalon; Putrescine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 1994 |
Role of excitatory amino acids in brainstem activation of spinal locomotor networks in larval lamprey.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Stem; Kynurenic Acid; Lampreys; Larva; Locomotion; Nerve Net; Quinoxalines; Receptors, Amino Acid; Spinal Cord; Stimulation, Chemical | 1994 |
Expression of NMDAR1-1a (N598Q)/NMDAR2A receptors results in decreased cell mortality.
Topics: 2-Amino-5-phosphonovalerate; Calcium; Cell Death; Cell Line; Humans; Kynurenic Acid; Mutation; Receptors, N-Methyl-D-Aspartate; Transfection | 1994 |
Potentiation of N-methyl-D-aspartate receptor-dependent afterdischarges in rat dentate gyrus following in vitro ethanol withdrawal.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Ethanol; Hippocampus; Kynurenic Acid; Magnesium; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 1994 |
Anoxia selectively depresses excitatory synaptic transmission in hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Evoked Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1994 |
Possible NMDA antagonist properties of drugs that affect high pressure neurological syndrome.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Alkaloids; Animals; Benzimidazoles; High Pressure Neurological Syndrome; Hippocampus; Indole Alkaloids; Kynurenic Acid; Mephenesin; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1994 |
Prevention by NMDA receptor antagonists of the centrally-evoked increases of cardiac inotropic responses in rabbits.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Electric Stimulation; Glutamates; Glutamic Acid; Ketamine; Kynurenic Acid; Male; Myocardial Contraction; Paraventricular Hypothalamic Nucleus; Rabbits; Receptors, N-Methyl-D-Aspartate | 1994 |
Preferential induction by stress of the N-methyl-D-aspartate recognition domain in discrete structures of rat brain.
Topics: 2-Amino-5-phosphonovalerate; Adrenal Cortex Hormones; Animals; Autoradiography; Behavior, Animal; Brain Chemistry; Cerebellum; Corpus Striatum; Cycloheximide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glycine; Hypothalamus; Kynurenic Acid; Male; N-Methylaspartate; Rats; Rats, Wistar; Stress, Physiological; Tritium | 1994 |
Activity-dependent enhancement of synaptic transmission in hippocampal slices treated with the phosphatase inhibitor calyculin A.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Evoked Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; Marine Toxins; Neurons, Afferent; Oxazoles; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1994 |
Posterior piriform and perirhinal cortex relay seizures evoked from the area tempestas: role of excitatory and inhibitory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Entorhinal Cortex; Excitatory Amino Acid Antagonists; GABA Agonists; Kynurenic Acid; Male; Microinjections; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, Glutamate; Seizures | 1994 |
Glutamate elicits an outward K+ current which is normally suppressed by a Ca2+/calmodulin-dependent protein kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alkaloids; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cholera Toxin; Dose-Response Relationship, Drug; Ganglia, Invertebrate; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kynurenic Acid; Membrane Potentials; Neurons; Pertussis Toxin; Piperazines; Potassium Channels; Protein Kinase Inhibitors; Snails; Staurosporine; Sulfonamides; Time Factors; Virulence Factors, Bordetella | 1994 |
Long-term potentiation in the avian hippocampus does not require activation of the N-methyl-D-aspartate (NMDA) receptor.
Topics: 2-Amino-5-phosphonovalerate; Animals; Columbidae; Dizocilpine Maleate; Evoked Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Optical imaging of parallel fiber activation in the rat cerebellar cortex: spatial effects of excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cerebellar Cortex; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Differential effects of NMDA and non-NMDA receptor antagonists on spinal cutaneous vs muscular nociception in the cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Iontophoresis; Ketamine; Kynurenic Acid; Muscles; Nerve Fibers; Nociceptors; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Skin Physiological Phenomena; Spinal Cord; Synaptic Transmission | 1993 |
Desensitization of the NMDA receptor complex by glycinergic ligands in cerebellar granule cell cultures.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Analysis of Variance; Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; Molecular Sequence Data; Neurons; Neurotoxins; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Strychnine; Time Factors | 1993 |
Whole cell and single channel analysis of the kinetics of glycine-sensitive N-methyl-D-aspartate receptor desensitization.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Female; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1993 |
Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Brain; Dizocilpine Maleate; Drug Administration Schedule; Glycine; Imipramine; In Vitro Techniques; Kynurenic Acid; Male; Mice; Receptors, N-Methyl-D-Aspartate | 1993 |
In vivo regulation of extracellular dopamine in the neostriatum: influence of impulse activity and local excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Corpus Striatum; Dialysis; Dopamine; Exocytosis; Extracellular Space; Kainic Acid; Kynurenic Acid; Microchemistry; Models, Neurological; N-Methylaspartate; Nerve Endings; Neurotoxins; Prosencephalon; Quinoxalines; Rats; Substantia Nigra; Tetrodotoxin | 1993 |
The impaired long-term potentiation in the CA1 field of the hippocampus of cognitive deficient microencephalic rats is restored by D-serine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cognition Disorders; Electric Stimulation; Electrophysiology; Hippocampus; In Vitro Techniques; Kynurenic Acid; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission; Time Factors | 1993 |
Pharmacological isolation and characterization of NMDA receptor-mediated synaptic potential in the dentate gyrus of rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Evidence that the parafascicular projection to the subthalamic nucleus is glutamatergic.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Electric Stimulation; Glutamates; Histocytochemistry; Kynurenic Acid; Male; Neural Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Thalamic Nuclei | 1993 |
Retrotrapezoid nucleus glutamate receptors: control of CO2-sensitive phrenic and sympathetic output.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Carbon Dioxide; Cats; Decerebrate State; Electrophysiology; Female; Kynurenic Acid; Male; Medulla Oblongata; Phrenic Nerve; Quinoxalines; Receptors, Glutamate; Respiration; Sympathetic Nervous System | 1993 |
Allosteric modulation of [3H]CGP 39653 binding by glycine in rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; Glycine; Kinetics; Kynurenic Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Tritium | 1993 |
Evidence for enhanced synaptic excitation in transplanted neostriatal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Fetal Tissue Transplantation; Glutamates; Glutamic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses; Synaptic Transmission | 1993 |
gamma-Acetylenic GABA produces axon-sparing neurodegeneration after focal injection into the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminobutyrate Transaminase; Alkynes; Amino Acids; Aminocaproates; Animals; Anticonvulsants; Axons; Choline O-Acetyltransferase; Dizocilpine Maleate; Hippocampus; In Vitro Techniques; Kynurenic Acid; Lyases; Male; Nerve Degeneration; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Transaminases | 1993 |
Newly learned auditory responses mediated by NMDA receptors in the owl inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Auditory Perception; Birds; Diazepam; Excitatory Amino Acid Antagonists; Inferior Colliculi; Ketamine; Kynurenic Acid; Learning; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Sound Localization; Synaptic Transmission; Visual Perception | 1996 |
Glutamate-independent long term depression in rat hippocampus by activation GABAA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Alanine; Animals; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Kynurenic Acid; Male; Muscimol; Neuronal Plasticity; Neurotoxins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A | 1996 |
Regionally distinct stoichiometry for N-methyl-D-aspartate receptor domains in brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Chemistry; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kinetics; Kynurenic Acid; Male; Nerve Tissue Proteins; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1996 |
Modulation of spinal visceral nociceptive transmission by NMDA receptor activation in the rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Afferent Pathways; Animals; Colon; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Nociceptors; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rectum; Serine; Skin; Spinal Cord; Synaptic Transmission | 1996 |
Use of subunit-specific antisense oligodeoxynucleotides to define developmental changes in the properties of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Base Sequence; Cerebral Cortex; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation, Developmental; Glycine; Kynurenic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oligonucleotides, Antisense; Oocytes; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Xenopus laevis | 1996 |
Olfactory nerve stimulation activates rat mitral cells via NMDA and non-NMDA receptors in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Olfactory Nerve; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate | 1996 |
Identification of a native low-conductance NMDA channel with reduced sensitivity to Mg2+ in rat central neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellar Nuclei; Electric Conductivity; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Ion Channel Gating; Kynurenic Acid; Magnesium; Membrane Potentials; Neurons; Organ Specificity; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spinal Cord; Transcription, Genetic | 1996 |
NMDA antagonist blockade of AT8 tau immunoreactive changes in neuronal cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Fetus; Fluorescent Antibody Technique; Kynurenic Acid; Microscopy, Confocal; Neurons; Piperidines; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; tau Proteins | 1996 |
Effects of parallel fiber stimulation on neurons of rat dorsal cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Stem; Cochlea; Cochlear Nucleus; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Kynurenic Acid; Male; Nerve Fibers; Quinoxalines; Rats; Rats, Sprague-Dawley | 1996 |
Differential action of NMDA antagonists on cholinergic neurotoxicity produced by N-methyl-D-aspartate and quinolinic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Choline O-Acetyltransferase; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Non-NMDA receptors transmit cardiopulmonary C fibre input in nucleus tractus solitarii in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Biguanides; Brain Mapping; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Kynurenic Acid; Lung; Male; N-Methylaspartate; Nerve Fibers; Neurons; Pressoreceptors; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Solitary Nucleus; Vagus Nerve | 1996 |
Postsynaptic glutamate uptake in rat cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ion Channel Gating; Kynurenic Acid; Membrane Potentials; Monosaccharide Transport Proteins; Neuroprotective Agents; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin | 1996 |
Size-related properties of vestibular afferent fibers in the frog: differential synaptic activation of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Afferent Pathways; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Isotonic Solutions; Kynurenic Acid; Nerve Fibers; Rana temporaria; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Ringer's Solution; Synapses; Vestibular Nuclei | 1996 |
NMDA receptor dependence of the input specific NMDA receptor-independent LTP in the hippocampal CA1 region.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium Channel Blockers; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Male; Nifedipine; Receptors, N-Methyl-D-Aspartate | 1997 |
Optical monitoring of glutaminergic excitatory postsynaptic potentials from the early developing embryonic chick brain stem.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Brain Stem; Chick Embryo; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction; Synapses; Time Factors; Vagus Nerve | 1993 |
Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Animals; Cells, Cultured; Cerebral Cortex; Child; Dizocilpine Maleate; Embryo, Mammalian; Evoked Potentials; Glycine; Homocysteine; Humans; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Comparing long-term depression with pharmacologically induced synaptic attenuations in young rat hippocampi.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Kynurenic Acid; Male; Neuronal Plasticity; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Synapses | 1997 |
A partial agonist model used in the allosteric modulation of the NMDA receptor.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Cerebellum; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Models, Biological; Protein Binding; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
EMD 95885, a new eliprodil analogue with higher affinity for the N-methyl-D-aspartate (NMDA) receptor.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
Excitatory amino acid receptors in the paraventricular hypothalamic nucleus mediate pressor response induced by carotid body chemoreceptor stimulation in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Carotid Body; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, Glutamate | 1997 |
Selective depression of the spinal polysynaptic reflex by the NMDA receptor antagonists in an isolated spinal cord in vitro.
Topics: Animals; Depression, Chemical; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Male; Piperazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Reflex, Monosynaptic; Serine; Spinal Cord; Spinal Nerve Roots; Strychnine; Valine | 1997 |
NMDA receptor-mediated differential laminar susceptibility to the intracellular Ca2+ accumulation induced by oxygen-glucose deprivation in rat neocortical slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Calcium; Cell Hypoxia; Excitatory Amino Acid Antagonists; Fura-2; GABA-A Receptor Antagonists; Glucose; In Vitro Techniques; Kinetics; Kynurenic Acid; Neocortex; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 1998 |
Modulation of neuronal mitochondrial membrane potential by the NMDA receptor: role of arachidonic acid.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Local; Animals; Arachidonic Acid; Biomarkers; Cells, Cultured; Cerebellum; Dibucaine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flow Cytometry; Fluorescent Dyes; Glycine; Intracellular Membranes; Kynurenic Acid; Membrane Potentials; Mitochondria; N-Methylaspartate; Piperidines; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rhodamine 123; Rhodamines; Sulfonamides | 1997 |
Glycine increases arterial pressure and augments NMDA-induced pressor responses in the dorsomedial and ventrolateral medulla of cats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cats; Dorsomedial Hypothalamic Nucleus; Drug Synergism; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Glycine; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Ventromedial Hypothalamic Nucleus | 1997 |
[Induction of rhythmical activity in digastric muscles in an in vitro brainstem preparation from adult mice].
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Stem; Electromyography; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Mastication; Mice; Mice, Inbred C57BL; Pyramidal Tracts | 1998 |
Receptors in lateral hypothalamic area involved in insular cortex sympathetic responses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Blood Pressure; Cerebral Cortex; Efferent Pathways; Electric Stimulation; Functional Laterality; Heart Rate; Hypothalamic Area, Lateral; Kidney; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Models, Neurological; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sympathetic Nervous System; Synapses | 1998 |
Chronic dosing with 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, modulates NMDA inhibition of muscarinic-coupled PI hydrolysis in rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Cerebral Cortex; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; In Vitro Techniques; Inositol; Kynurenic Acid; Male; Muscarinic Agonists; N-Methylaspartate; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calbindin 1; Calbindins; Calcium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Cyclic N-Oxides; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Ganglia, Spinal; Glutamic Acid; Glutathione; Kynurenic Acid; Mice; Motor Neurons; Mutagenesis; Nerve Tissue Proteins; Neurotoxins; Nitrogen Oxides; Oxidative Stress; Receptors, AMPA; S100 Calcium Binding Protein G; Spider Venoms; Spinal Cord; Superoxide Dismutase; Synapses | 1998 |
Pharmacological profile of the isomers of the GluR-specific agonist ATPA.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoxazoles; Kynurenic Acid; Propionates; Quinoxalines; Rats; Receptors, Glutamate; Stereoisomerism | 1998 |
Properties of NMDA receptors in rat spinal cord motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Ion Channel Gating; Kainic Acid; Kynurenic Acid; Magnesium; Male; Motor Neurons; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Ferrous iron modulates quinolinate-mediated [3H]MK-801 binding to rat brain synaptic membranes in the presence of glycine and spermidine.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Binding Sites; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ferrous Compounds; Glutamic Acid; Glycine; Inhibitory Concentration 50; Kynurenic Acid; Male; Quinolinic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Synaptic Membranes | 1999 |
Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Animals, Suckling; Bicuculline; Cycloheximide; Darkness; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation, Developmental; Glycine; Kynurenic Acid; Light; Male; Models, Neurological; Nerve Tissue Proteins; Neuronal Plasticity; Optic Nerve; Photic Stimulation; Piperidines; Protein Synthesis Inhibitors; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sensory Deprivation; Synapses; Vision, Ocular; Visual Cortex; Zinc | 1999 |
Role of glutamate receptor subtypes in the lamprey respiratory network.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Kynurenic Acid; Lampreys; Neurons; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Respiration | 1999 |
Synaptically released glutamate reduces gamma-aminobutyric acid (GABA)ergic inhibition in the hippocampus via kainate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Hippocampus; Kynurenic Acid; Receptors, AMPA; Receptors, Kainic Acid; Seizures | 1999 |
Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons.
Topics: Analgesics, Opioid; Animals; Calcium; Cell Survival; Dizocilpine Maleate; Dynorphins; Embryo, Mammalian; Kynurenic Acid; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Neurotoxins; Peptide Fragments; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine | 1999 |
Glutamate does not mediate acute neuronal damage after spreading depression induced by O2/glucose deprivation in the hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Ischemia; Cortical Spreading Depression; Evoked Potentials; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Neurotoxins; Oxygen; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Temperature | 2000 |
Modulation and function of kynurenic acid in the immature rat brain.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; Animals; Brain; Dextroamphetamine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glucose; Kynurenic Acid; Kynurenine 3-Monooxygenase; Male; Microdialysis; Mixed Function Oxygenases; N-Methylaspartate; Neurons; Pyruvates; Rats; Rats, Sprague-Dawley | 1999 |
Differential effects of NMDA-receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Hypoxia; Cells, Cultured; Excitatory Amino Acid Antagonists; Glucose; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Long-term potentiation of primary afferent neurotransmission at trigeminal synapses of juvenile rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Chelating Agents; Egtazic Acid; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Neurons, Afferent; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Trigeminal Nuclei | 2000 |
Enhancement of NMDA-induced current by the putative NR2B selective antagonist ifenprodil.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 2000 |
The HIV-1 coat protein gp120 and some of its fragments potently activate native cerebral NMDA receptors mediating neuropeptide release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Cholecystokinin; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; HIV Envelope Protein gp120; HIV-1; Indoles; Kynurenic Acid; Male; Maleimides; Neurons; Nitroarginine; Peptide Fragments; Pipecolic Acids; Piperazines; Piperidines; Potassium; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Somatostatin; Synaptic Transmission; Synaptosomes; Zinc | 2000 |
Nicotinic acetylcholine receptor-mediated synaptic potentials in rat neocortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholinesterase; Animals; Bicuculline; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Kynurenic Acid; Mecamylamine; Neocortex; Neostigmine; Nicotinic Antagonists; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Transmission | 2000 |
Local opiate withdrawal in locus coeruleus neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Barium; Bicuculline; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Kynurenic Acid; Locus Coeruleus; Male; Membrane Potentials; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Neurons; Ouabain; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tetrodotoxin; Thionucleotides | 2001 |
Multiple rostral medullary nuclei can influence breathing in awake goats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Carbon Dioxide; Electromyography; Excitatory Amino Acid Antagonists; Female; Goats; Heart Rate; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Neurons; Orchiectomy; Oxygen Consumption; Quinoxalines; Respiratory Mechanics; Respiratory Muscles; Tidal Volume; Vestibular Nuclei | 2001 |
Neurotransmitters in the thalamus relaying visceral input to the insular cortex in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Antagonists; Animals; Atropine; Cerebral Cortex; Cobalt; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamates; Kynurenic Acid; Male; Muscarinic Antagonists; Neurons; Neurotransmitter Agents; Phentolamine; Picrotoxin; Quinoxalines; Rats; Rats, Wistar; Thalamus; Vagus Nerve; Viscera | 2001 |
Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats.
Topics: 2-Amino-5-phosphonovalerate; Alkaloids; Analgesics; Animals; Benzophenanthridines; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Injections, Spinal; Kynurenic Acid; Magnesium Sulfate; Male; Neurons; Nitric Oxide Synthase; Pain Measurement; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spine | 2001 |
Caudal ventrolateral medulla mediates the depressor response elicited by the greater splanchnic nerve afferent stimulation in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Electric Stimulation; Excitatory Amino Acid Antagonists; Heart Rate; Kynurenic Acid; Lidocaine; Male; Medulla Oblongata; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Splanchnic Nerves | 2002 |
Effects of excitatory amino acid antagonists on the activity of inferior colliculus neurons during sleep and wakefulness.
Topics: 2-Amino-5-phosphonovalerate; Animals; Auditory Cortex; Auditory Pathways; Electric Stimulation; Evoked Potentials, Auditory; Excitatory Amino Acid Antagonists; Guinea Pigs; Inferior Colliculi; Iontophoresis; Kynurenic Acid; Sleep; Wakefulness | 2002 |
Contributions from rostral medullary nuclei to coordination of swallowing and breathing in awake goats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Consciousness; Deglutition; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Goats; Kynurenic Acid; Medulla Oblongata; Microinjections; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Respiratory Mechanics | 2002 |
Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Behavior, Animal; Dizocilpine Maleate; Dynorphins; Endorphins; Enkephalins; Excitatory Amino Acid Antagonists; Injections, Spinal; Kynurenic Acid; Male; Mice; Morphine; Neurokinin A; Nociceptors; Peptide Fragments; Piperidines; Protein Precursors; Receptors, N-Methyl-D-Aspartate; Receptors, Tachykinin; Substance P | 2002 |
Evidence against the presence of NMDA receptors at a central glutamatergic synapse in leeches.
Topics: 2-Amino-5-phosphonovalerate; Animals; Association Learning; Central Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kynurenic Acid; Leeches; Motor Neurons; N-Methylaspartate; Neurons, Afferent; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex; Synapses; Synaptic Transmission | 2002 |
Involvement of glutamate in gastrointestinal vago-vagal reflexes initiated by gastrointestinal distention in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Digestive System Physiological Phenomena; Duodenum; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Solitary Nucleus; Stomach; Vagus Nerve | 2003 |
Involvement of N-methyl-D-aspartate receptors in post-hypoxic depression of the dorsomedial medulla in cats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Gas Analysis; Blood Pressure; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Heart Rate; Hypoxia; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spinal Nerves | 2003 |
Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Allosteric Regulation; Allosteric Site; Animals; Excitatory Amino Acid Antagonists; Gene Products, tat; Hippocampus; HIV-1; Humans; Ketamine; Kynurenic Acid; Neurons; Patch-Clamp Techniques; Protein Interaction Mapping; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; tat Gene Products, Human Immunodeficiency Virus; Zinc | 2003 |
Behavioral effects of NMDA receptor agonists and antagonists in combination with nitric oxide-related compounds.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Gallic Acid; Guanidines; Indazoles; Injections, Intraperitoneal; Kynurenic Acid; Molsidomine; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2003 |
Sympathoexcitation by PVN-injected bicuculline requires activation of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Blood Pressure; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; Heart Rate; Hypothalamus; Injections; Kidney; Kynurenic Acid; Male; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 2003 |
Evidence for a glutamatergic modulation of the cholinergic function in the human enteric nervous system via NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Aged; Colon, Ascending; Colon, Sigmoid; Enteric Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Immunohistochemistry; In Vitro Techniques; Kynurenic Acid; Male; Muscle, Smooth; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate | 2003 |
Glutamate release increases during mossy-CA3 LTP but not during Schaffer-CA1 LTP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Calcium; Colforsin; Coloring Agents; Cyclopropanes; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Magnesium; Male; Mossy Fibers, Hippocampal; Neuroglia; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Distinct mechanisms of bidirectional activity-dependent synaptic plasticity in superficial and deep layers of rat entorhinal cortex.
Topics: Animals; Calcium Channel Blockers; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Models, Neurological; Neuronal Plasticity; Nifedipine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Valine | 2004 |
Subthreshold contribution of N-methyl-d-aspartate receptors to long-term potentiation induced by low-frequency pairing in rat hippocampal CA1 pyramidal cells.
Topics: Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Kynurenic Acid; Long-Term Potentiation; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2004 |
Memantine inhibits and reverses the Alzheimer type abnormal hyperphosphorylation of tau and associated neurodegeneration.
Topics: 2-Amino-5-phosphonovalerate; Alzheimer Disease; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kynurenic Acid; Memantine; Microtubule-Associated Proteins; Nerve Degeneration; Neurofibrils; Neuroprotective Agents; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; tau Proteins | 2004 |
Tracheal tone and the role of ionotropic glutamate receptors in the nucleus ambiguus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dogs; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kynurenic Acid; Male; Medulla Oblongata; Muscle Tonus; Muscle, Smooth; Receptors, Glutamate; Trachea; Xanthurenates | 2004 |
Putative NMDA receptors in Hydra: a biochemical and functional study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding Sites; Cell Membrane; Concanavalin A; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamic Acid; Glutathione; Glycine; Hydra; Kynurenic Acid; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine | 2004 |
Respiratory responses evoked by blockades of ionotropic glutamate receptors within the Bötzinger complex and the pre-Bötzinger complex of the rabbit.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Blood Pressure; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hypercapnia; Hypoxia; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Neurons; Phrenic Nerve; Rabbits; Respiration; Time Factors; Vagotomy | 2005 |
Schwann cells exhibit excitotoxicity consistent with release of NMDA receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Calcium; Cell Death; Cells, Cultured; Culture Media, Conditioned; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Glutamic Acid; Hippocampus; Kynurenic Acid; Microtubule-Associated Proteins; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schwann Cells; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
GABAergic neurons in the central region of the spinal cord: a novel substrate for sympathetic inhibition.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Autonomic Fibers, Preganglionic; Axonal Transport; Bicuculline; Chlorides; Electric Stimulation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Herpesvirus 1, Suid; Homeostasis; In Situ Hybridization; Interneurons; Isoenzymes; Kynurenic Acid; Male; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; RNA, Messenger; Spinal Cord; Strychnine | 2005 |
D-serine enhances impaired long-term potentiation in CA1 subfield of hippocampal slices from aged senescence-accelerated mouse prone/8.
Topics: Age Factors; Aging; Analysis of Variance; Animals; D-Amino-Acid Oxidase; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Mice; Mice, Neurologic Mutants; Serine; Valine | 2005 |
NMDA receptors mediate feeding elicited by neuropeptide Y in the lateral and perifornical hypothalamus.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Feeding Behavior; Hypothalamus; Kynurenic Acid; Male; Microinjections; Neurons; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Satiety Response; Statistics, Nonparametric; Valine | 2005 |
Excitatory amino acid receptors are involved in morphine-induced synchronous oscillatory discharges in the locus coeruleus of rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Evoked Potentials; Injections, Intraventricular; Kynurenic Acid; Locus Coeruleus; Male; Morphine; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Valine | 2005 |
Endogenous activation of nicotinic receptors underlies sympathetic tone generation in neonatal rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Animals; Animals, Newborn; Autonomic Fibers, Preganglionic; Cholinergic Fibers; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glycine; In Vitro Techniques; Interneurons; Kynurenic Acid; Mecamylamine; Nerve Tissue Proteins; Nicotinic Agonists; Nicotinic Antagonists; Organophosphonates; Phenylalanine; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spinal Cord; Splanchnic Nerves; Sympathetic Fibers, Postganglionic; Synaptic Transmission | 2006 |
Effects of intertrigeminal region NMDA and non-NMDA receptors on respiratory responses in rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Apnea; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Trigeminal Nuclei | 2007 |
Glutamatergic inputs in the hypothalamic paraventricular nucleus maintain sympathetic vasomotor tone in hypertension.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Heart Rate; Hypertension; Kynurenic Acid; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Vasomotor System | 2007 |
Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site.
Topics: 2-Amino-5-phosphonovalerate; Agmatine; Animals; Cycloserine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Injections, Spinal; Ion Channels; Kynurenic Acid; Mice; Morphine; Neurokinin A; Nociceptors; Pain; Peptide Fragments; Piperidines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Tachykinin; Substance P | 2007 |
The role of NMDA and non-NMDA receptors in the NTS in mediating three distinct sympathoinhibitory reflexes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biguanides; Blood Pressure; Cholecystokinin; GABA Agonists; Heart Rate; Kynurenic Acid; Male; Muscimol; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Solitary Nucleus; Synaptic Transmission | 2007 |
Effects of in situ administration of excitatory amino acid antagonists on rapid microglial and astroglial reactions in rat hippocampus following traumatic brain injury.
Topics: Animals; Astrocytes; Brain Injuries; CD11b Antigen; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Ion Channels; Kynurenic Acid; Male; Microglia; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Sodium Channel Blockers; Time Factors; Treatment Outcome; Up-Regulation; Valine | 2008 |
Depolarization-induced release of endocannabinoids by murine dorsal motor nucleus of the vagus nerve neurons differentially regulates inhibitory and excitatory neurotransmission.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arachidonic Acids; Benzoxazines; Brain Stem; Calcium Signaling; Cannabinoid Receptor Modulators; Capsaicin; Efferent Pathways; Endocannabinoids; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Inhibitory Postsynaptic Potentials; Kynurenic Acid; Male; Mice; Mice, Inbred C57BL; Morpholines; Naphthalenes; Neurons; Piperidines; Pyrazoles; Pyridazines; Receptor, Cannabinoid, CB1; Receptors, Presynaptic; Rimonabant; Tetrodotoxin; Vagus Nerve | 2009 |
Vesicular glutamate filling and AMPA receptor occupancy at the calyx of Held synapse of immature rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Benzothiadiazines; Brain Stem; Excitatory Postsynaptic Potentials; Glutamic Acid; Kynurenic Acid; Patch-Clamp Techniques; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Vesicles; Temperature; Tetrodotoxin | 2009 |
Activation of N-methyl-D-aspartate (NMDA) receptors in the dorsal vagal complex lowers glucose production.
Topics: 2-Amino-5-phosphonovalerate; Animals; Gene Knockdown Techniques; Glucose; Glycine; Humans; Kynurenic Acid; Liver; Male; N-Methylaspartate; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vagotomy; Vagus Nerve | 2010 |
Multivesicular release differentiates the reliability of synaptic transmission between the visual cortex and the somatosensory cortex.
Topics: Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Mice; Models, Neurological; Neural Pathways; Neurons; Nonlinear Dynamics; Patch-Clamp Techniques; Potassium Channel Blockers; Probability; Somatosensory Cortex; Synapses; Synaptic Transmission; Synaptic Vesicles; Tetraethylammonium; Valine; Visual Cortex | 2010 |
Protein kinase C modulates NMDA receptors in the myenteric plexus of the guinea pig ileum during in vitro ischemia and reperfusion.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzophenanthridines; Guinea Pigs; Ileum; In Vitro Techniques; Isoquinolines; Kynurenic Acid; Male; Models, Animal; Myenteric Plexus; Phosphorylation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Sulfonamides | 2011 |
The role of the glutathione system in seizures induced by diphenyl diselenide in rat pups.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Benzene Derivatives; Buthionine Sulfoximine; Catalase; Female; Glutathione; Glutathione Peroxidase; Kynurenic Acid; Male; Organoselenium Compounds; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances | 2011 |
Sympathoexcitation and pressor responses induced by ethanol in the central nucleus of amygdala involves activation of NMDA receptors in rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amygdala; Animals; Blood Pressure; Ethanol; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Medulla Oblongata; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Splanchnic Nerves | 2014 |
Blockade of glutamatergic transmission in perirhinal cortex impairs object recognition memory in macaques.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Kynurenic Acid; Macaca; Male; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Temporal Lobe; Time Factors; Visual Perception | 2015 |
A Metabotropic-Like Flux-Independent NMDA Receptor Regulates Ca2+ Exit from Endoplasmic Reticulum and Mitochondrial Membrane Potential in Cultured Astrocytes.
Topics: 2-Amino-5-phosphonovalerate; Aniline Compounds; Animals; Astrocytes; Benzimidazoles; Calcium; Calcium Channel Blockers; Carbocyanines; Cells, Cultured; Dizocilpine Maleate; Endoplasmic Reticulum; Inositol 1,4,5-Trisphosphate Receptors; Ions; Kynurenic Acid; Membrane Potential, Mitochondrial; N-Methylaspartate; Protein Subunits; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Xanthenes | 2015 |
Differential regulation of NMDA receptors by d-serine and glycine in mammalian spinal locomotor networks.
Topics: 2-Amino-5-phosphonovalerate; Animals; Efferent Pathways; Glycine; Interneurons; Kynurenic Acid; Mice; Mice, Inbred C57BL; Motor Activity; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Spinal Nerve Roots; Synapses | 2017 |
Subsaturation of the N-methyl-D-aspartate receptor glycine site allows the regulation of bursting activity in juvenile rat nigral dopamine neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dopaminergic Neurons; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Kynurenic Acid; Pars Compacta; Phosphinic Acids; Propanolamines; Rats; Receptors, N-Methyl-D-Aspartate; Serine | 2019 |