kynuramine has been researched along with n-acetyl-n-formyl-5-methoxykynurenamine in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.89) | 18.7374 |
| 1990's | 1 (1.89) | 18.2507 |
| 2000's | 37 (69.81) | 29.6817 |
| 2010's | 12 (22.64) | 24.3611 |
| 2020's | 2 (3.77) | 2.80 |
| Authors | Studies |
|---|---|
| Amato, F; Kelly, RW; Seamark, RF | 1 |
| Balzer, I; Behrmann, G; Fuhrberg, B; Hardeland, R; Meyer, TJ; Poeggeler, B; Reiter, RJ; Uría, H; Wolf, R | 1 |
| Burkhardt, S; Cabrera, J; Hardeland, R; Karbownik, M; Reiter, RJ; Tan, DX | 1 |
| Burkhardt, S; Hardeland, R; Huo, YS; Kohen, R; Manchester, LC; Mayo, JC; Reiter, RJ; Sainz, RM; Shohami, E; Tan, DX | 1 |
| Campa, A; Catalani, LH; Ximenes, VF | 1 |
| Allegra, M; Avellone, G; Ceraulo, L; D'Arpa, D; Livrea, MA; Tesoriere, L | 1 |
| Hardeland, R; Niebergall, R; Poeggeler, B; Zelosko, V | 1 |
| Campa, A; Henrique Catalani, L; Rodrigues, MR; Rodriguez, D; Russo, M | 1 |
| Hardeland, R; Lopez-Burillo, S; Manchester, LC; Mayo, JC; Poeggeler, B; Reiter, RJ; Sainz, RM; Tan, DX | 1 |
| Claudy, D; Claustrat, B; Déchaud, H; Harthé, C; Pévet, P; Vivien-Roels, B | 1 |
| de Almeida, EA; de Medeiros, MH; Di Mascio, P; Klitzke, CF; Martinez, GR | 1 |
| Blashko, EL; Filatova, EV; Orlov, AA; Pozdeyev, NV; Rozov, SV; Volkova, AV; Zhloba, AR | 1 |
| Almeida, EA; Di Mascio, P; Klitzke, CF; Martinez, GR; Medeiros, MH | 1 |
| Campa, A; Carvalho, SR; Catalani, LH; Rodrigues, MR; Silva, SO; Ximenes, VF | 1 |
| Amarante-Mendes, GP; Bueno-da-Silva, AE; Campa, A; Rodrigues, MR; Silva, SO; Ximenes, VF | 1 |
| Behrends, A; Grube, S; Haldar, C; Hardeland, R; Ness, H; Poeggeler, B | 1 |
| Hardeland, R; Leon, J; Mayo, JC; Reiter, RJ; Rodriguez, C; Sainz, RM; Tan, DX | 1 |
| Hardeland, R; Leon, J; Manchester, LC; Mayo, JC; Poeggeler, B; Reiter, RJ; Sainz, RM; Tan, DX | 1 |
| Campa, A; Catalani, LH; Kettle, AJ; Maghzal, GJ; Rodrigues, MR; Silva, SO; Ximenes, VF | 1 |
| Campa, A; Catalani, LH; Livramento, JA; Silva, SO; Ximenes, VF | 1 |
| Almeida, EA; Di Mascio, P; Klitzke, CF; Martinez, GR; Medeiros, MH; Onuki, J; Prado, FM | 1 |
| Campa, A; Carvalho, SR; Okada, SS; Silva, SO; Ximenes, VF | 1 |
| Hardeland, R; Heer, C; Laatsch, H; Than, NN | 1 |
| Acuña-Castroviejo, D; Camacho, E; Carrión, MD; Entrena, A; Escames, G; Espinosa, A; Gallo, MA; León, J; López, LC; Reiter, RJ; Rodríguez, MI; Tan, DX; Tapias, V | 1 |
| Flores, LJ; Manchester, LC; Reiter, RJ; Tan, DX; Terron, MP | 1 |
| Di Mascio, P; Manchester, LC; Martinez, GR; Prado, FM; Reiter, RJ; Tan, DX | 1 |
| Budu, A; Bueno, VB; Catalani, LH; Garcia, CR; Peres, R | 1 |
| Bueno, VB; Catalani, LH; de Oliveira, GH; Fernandes, JR; Machado, RG; Ximenes, VF | 1 |
| Anzai, K; Manda, K; Ueno, M | 2 |
| Catalá, A; Fagali, N | 1 |
| Daya, S; Glass, BD; Maharaj, DS | 1 |
| Hardeland, R; Seever, K | 1 |
| Cabello, C; de Menezes, ML; Fernandes, JR; Rodrigues, AP; Ximenes, VF | 1 |
| Ximenes, VF | 1 |
| Antonova, M; Korik, E; Semak, I; Slominski, A; Wortsman, J | 1 |
| Berger, S; Bouchet, JP; Boutin, JA; Delagrange, P; Ferry, G; Hennig, P; Marcheteau, E; Moulharat, N | 1 |
| Bonnefont-Rousselot, D; Collin, F; Gardès-Albert, M; Jore, D; Marchetti, C; Yous, S | 1 |
| Hardeland, R; Reiter, RJ; Tan, DX | 1 |
| Caldas, SS; Cruz, BP; Geihs, MA; Maciel, FE; Monserrat, JM; Nery, LE; Primel, EG; Vargas, MA | 1 |
| Carvalho, DA; Fernandes, JR; Padovan, CZ; Ximenes, VF | 1 |
| Gonzalez, FJ; Idle, JR; Li, F; Ma, X; Niu, S; Tan, DX; Zhang, L | 1 |
| Arendash, GW; Bradshaw, PC; Buzzeo, R; Cao, C; Copes, N; Dragicevic, N; Jin, J; Mamcarz, M; O'Neal-Moffitt, G; Olcese, JM; Tan, J | 1 |
| Galano, A; Reiter, RJ; Tan, DX | 1 |
| Fischer, TW; Janjetovic, Z; Kim, TK; Kleszczynski, K; Li, W; Lin, Z; Reiter, RJ; Slominski, AT; Sweatman, T | 1 |
| Kim, TK; Li, W; Lin, Z; Slominski, AT; Tidwell, WJ | 1 |
| Bonior, J; Czech, U; Goralska, M; Jaworek, J; Kot, M; Pierzchalski, P; Reiter, RJ; Szklarczyk, J; Tomaszewska, R | 1 |
| Dong, X; Meng, P; Qin, W; Tan, G; Wang, H; Wu, H; Yuan, J | 1 |
| Gozdowska, M; Kalamarz-Kubiak, H; Kulczykowska, E; Sokołowska, E | 1 |
| Bordin-Junior, NA; de Almeida, EA; de Campos Zuccari, DAP; de Castro, TB | 1 |
| Bonior, J; Góralska, M; Jastrzębska, M; Jaworek, J; Leja-Szpak, A; Link-Lenczowski, P; Nawrot-Porąbka, K; Pierzchalski, P | 1 |
| Chen, N; Deng, Y; Gong, C; Li, L; Liu, X; Rong, K; Yang, R; Zhao, G; Zheng, H | 1 |
| Chiba, A; Hattori, A; Iwashita, H; Maruyama, Y; Matsumoto, Y; Watanabe, K | 1 |
5 review(s) available for kynuramine and n-acetyl-n-formyl-5-methoxykynurenamine
| Article | Year |
|---|---|
Measurement of melatonin and its metabolites: importance for the evaluation of their biological roles.
Topics: Animals; Chromatography, High Pressure Liquid; Humans; Kynuramine; Mass Spectrometry; Melatonin; Reference Standards | 2005 |
One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species?
Topics: Animals; Biological Availability; Humans; Kynuramine; Melatonin | 2007 |
Melatonin: new places in therapy.
Topics: Animals; Antioxidants; Circadian Rhythm; Humans; Kynuramine; Melatonin; Neuroprotective Agents; Pineal Gland; Reactive Oxygen Species | 2007 |
Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines.
Topics: Animals; Biogenic Amines; Humans; Indoles; Kynuramine; Melatonin; Models, Molecular | 2009 |
On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK.
Topics: Free Radical Scavengers; Kinetics; Kynuramine; Melatonin; Models, Molecular; Thermodynamics | 2013 |
48 other study(ies) available for kynuramine and n-acetyl-n-formyl-5-methoxykynurenamine
| Article | Year |
|---|---|
N-acetyl-5-methoxy kynurenamine, a brain metabolite of melatonin, is a potent inhibitor of prostaglandin biosynthesis.
Topics: Animals; Aspirin; Brain; Cattle; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; In Vitro Techniques; Kynuramine; Male; Melatonin; Microsomes; Propiophenones; Seminal Vesicles; Sheep | 1984 |
On the primary functions of melatonin in evolution: mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals.
Topics: 5-Methoxytryptamine; Animals; Biological Evolution; Dinoflagellida; Free Radical Scavengers; Hydrogen-Ion Concentration; Kynuramine; Light; Melatonin; Monoamine Oxidase; Oxidants, Photochemical; Photoperiod; Signal Transduction | 1995 |
DNA oxidatively damaged by chromium(III) and H(2)O(2) is protected by the antioxidants melatonin, N(1)-acetyl-N(2)-formyl-5-methoxykynuramine, resveratrol and uric acid.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Chromatography, High Pressure Liquid; Chromium Compounds; Deoxyguanosine; DNA Damage; Hydrogen Peroxide; Kynuramine; Melatonin; Molecular Structure; Resveratrol; Stilbenes; Uric Acid | 2001 |
N1-acetyl-N2-formyl-5-methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amyloid beta-Peptides; Animals; Antioxidants; Cell Death; Cells, Cultured; Chelating Agents; Deoxyguanosine; Ferrous Compounds; Free Radicals; Glutamic Acid; Hydrogen Peroxide; Kynuramine; Lipid Peroxidation; Liver; Melatonin; Metals, Heavy; Models, Biological; Neurons; Peptide Fragments; Rats | 2001 |
Oxidation of melatonin and tryptophan by an HRP cycle involving compound III.
Topics: Chromatography, High Pressure Liquid; Horseradish Peroxidase; Hydrogen Peroxide; Kynuramine; Melatonin; Oxidation-Reduction; Tryptophan | 2001 |
Oxidation of melatonin by oxoferryl hemoglobin: a mechanistic study.
Topics: Animals; Cattle; Chlorine; Gas Chromatography-Mass Spectrometry; Hemoglobins; Hydrogen Peroxide; Kinetics; Kynuramine; Magnetic Resonance Spectroscopy; Melatonin; Methemoglobin; Oxidation-Reduction; Oxides; Spectrophotometry, Ultraviolet; Time Factors | 2001 |
Oxidation of melatonin by carbonate radicals and chemiluminescence emitted during pyrrole ring cleavage.
Topics: Carbonates; Kynuramine; Luminescent Measurements; Melatonin; Oxidation-Reduction; Pyrroles | 2003 |
Interferon-gamma independent oxidation of melatonin by macrophages.
Topics: Animals; Azides; Hydrogen Peroxide; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynuramine; Macrophages; Melatonin; Mice; Mice, Knockout; Oxidation-Reduction; Peroxidase; Tetradecanoylphorbol Acetate; Tryptophan; Tryptophan Oxygenase | 2003 |
Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical.
Topics: Antioxidants; Ascorbic Acid; Benzothiazoles; Cations; Chromans; Chromatography, High Pressure Liquid; Electrochemistry; Free Radical Scavengers; Free Radicals; Glutathione; Hydrogen-Ion Concentration; Kynuramine; Mechanics; Melatonin; NAD; NADP; Sulfonic Acids | 2003 |
Radioimmunoassay of N-acetyl-N-formyl-5-methoxykynuramine (AFMK): a melatonin oxidative metabolite.
Topics: Animals; Diatomaceous Earth; Humans; Kynuramine; Male; Melatonin; Octanols; Oxidation-Reduction; Rabbits; Radioimmunoassay; Rats; Rats, Wistar | 2003 |
Oxidation of melatonin by singlet molecular oxygen (O2(1deltag)) produces N1-acetyl-N2-formyl-5-methoxykynurenine.
Topics: Chromatography, High Pressure Liquid; Kinetics; Kynuramine; Mass Spectrometry; Melatonin; Oxidation-Reduction; Singlet Oxygen | 2003 |
N1-acetyl-N2-formyl-5-methoxykynuramine is a product of melatonin oxidation in rats.
Topics: Animals; Kynuramine; Melatonin; Oxidation-Reduction; Rats; Retina | 2003 |
Synthesis of internal labeled standards of melatonin and its metabolite N1-acetyl-N2-formyl-5-methoxykynuramine for their quantification using an on-line liquid chromatography-electrospray tandem mass spectrometry system.
Topics: Biochemistry; Calibration; Chromatography, Liquid; Humans; Kynuramine; Melatonin; Spectrometry, Mass, Electrospray Ionization | 2004 |
Oxidation of melatonin and its catabolites, N1-acetyl-N2 -formyl-5-methoxykynuramine and N1-acetyl-5-methoxykynuramine, by activated leukocytes.
Topics: Catalase; Cells, Cultured; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Kinetics; Kynuramine; Leukocytes; Lipopolysaccharides; Melatonin; Neutrophil Activation; Oxidation-Reduction; Peroxidase; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2004 |
Neutrophils as a specific target for melatonin and kynuramines: effects on cytokine release.
Topics: Analysis of Variance; Cells, Cultured; Cytokines; Humans; Kynuramine; Melatonin; Neutrophils; Oxidation-Reduction | 2004 |
Photocatalytic actions of the pesticide metabolite 2-hydroxyquinoxaline: destruction of antioxidant vitamins and biogenic amines - implications of organic redox cycling.
Topics: Amines; Antioxidants; Ascorbic Acid; Catalysis; Catecholamines; Dimerization; Dopamine; Ethanol; Free Radical Scavengers; Kynuramine; Light; Melatonin; Models, Chemical; Oxidants; Oxidation-Reduction; Oxygen; Piperazines; Quinoxalines; Serotonin; Spectrophotometry; Time Factors; Ultraviolet Rays; Vitamin E; Vitamins | 2004 |
Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Indoles; Kynuramine; Lipopolysaccharides; Macrophage Activation; Macrophages; Melatonin; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Superoxides | 2005 |
Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin.
Topics: Animals; Catalase; Cell-Free System; Humans; Hydrogen Peroxide; Kynuramine; Melatonin; NAD; Nicotinamide Mononucleotide; Oxyhemoglobins; PC12 Cells; Rats; Superoxide Dismutase | 2005 |
Superoxide-dependent oxidation of melatonin by myeloperoxidase.
Topics: Animals; Antioxidants; Catalase; Catalysis; Cattle; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dimerization; Dose-Response Relationship, Drug; Free Radicals; Heme; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Kynuramine; Liver; Mass Spectrometry; Melatonin; Models, Chemical; Neutrophils; Oxygen; Ozone; Peroxidase; Protein Binding; Superoxides; Taurine; Time Factors; Xanthine Oxidase | 2005 |
High concentrations of the melatonin metabolite, N1-acetyl-N2-formyl-5-methoxykynuramine, in cerebrospinal fluid of patients with meningitis: a possible immunomodulatory mechanism.
Topics: Adjuvants, Immunologic; Biomarkers; Chromatography, High Pressure Liquid; Humans; Kynuramine; Melatonin; Meningitis | 2005 |
Melatonin and its kynurenin-like oxidation products affect the microbicidal activity of neutrophils.
Topics: Cells, Cultured; Humans; Hypochlorous Acid; Kynuramine; Melatonin; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Phagocytosis; Staphylococcus aureus | 2006 |
Reactions of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK) with the ABTS cation radical: identification of new oxidation products.
Topics: Antioxidants; Benzothiazoles; Cations; Dimerization; Free Radical Scavengers; Free Radicals; Kynuramine; Magnetic Resonance Spectroscopy; Melatonin; Molecular Structure; Nitro Compounds; Oxidation-Reduction; Reactive Nitrogen Species; Sulfonic Acids | 2006 |
Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin.
Topics: Animals; Brain; Carbolines; Corpus Striatum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Harmine; In Vitro Techniques; Kinetics; Kynuramine; Male; Melatonin; Nitric Oxide Synthase Type I; Rats; Rats, Wistar | 2006 |
Novel rhythms of N1-acetyl-N2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation.
Topics: Adaptation, Physiological; Circadian Rhythm; Eichhornia; Kynuramine; Light; Melatonin; Phytotherapy; Plant Physiological Phenomena | 2007 |
N1-acetyl-N2-formyl-5-methoxykynuramine modulates the cell cycle of malaria parasites.
Topics: Animals; Cell Cycle; Erythrocytes; Kynuramine; Melatonin; Mice; Mice, Inbred BALB C; Plasmodium chabaudi; Plasmodium falciparum | 2007 |
The effect of pH on horseradish peroxidase-catalyzed oxidation of melatonin: production of N1-acetyl-N2-5-methoxykynuramine versus radical-mediated degradation.
Topics: Horseradish Peroxidase; Hydrogen-Ion Concentration; Kynuramine; Melatonin; Oxidation-Reduction | 2007 |
AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Cerebral Cortex; Comet Assay; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Kynuramine; Lipid Peroxidation; Male; Melatonin; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; X-Rays | 2007 |
The effect of melatonin and structural analogues on the lipid peroxidation of triglycerides enriched in omega-3 polyunsaturated fatty acids.
Topics: 5-Methoxytryptamine; Benzene Derivatives; Biphenyl Compounds; Butylated Hydroxytoluene; Cell-Free System; Docosahexaenoic Acids; Fatty Acids, Omega-3; Free Radical Scavengers; Kynuramine; Lipid Peroxidation; Lipids; Luminescent Measurements; Melatonin; Oxidation-Reduction; Picrates; Reactive Oxygen Species; Serotonin; Thiobarbituric Acid Reactive Substances; Triglycerides; Tryptophan | 2007 |
Novel pathway for N1-acetyl-5-methoxykynuramine: UVB-induced liberation of carbon monoxide from precursor N1-acetyl-N2-formyl-5-methoxykynuramine.
Topics: Carbon Monoxide; Hydroxyl Radical; Kynuramine; Melatonin; Photochemistry; Ultraviolet Rays | 2008 |
The co-catalytic effect of chlorpromazine on peroxidase-mediated oxidation of melatonin: enhanced production of N1-acetyl-N2-formyl-5-methoxykynuramine.
Topics: Animals; Antioxidants; Antipsychotic Agents; Chlorpromazine; Humans; Kynuramine; Melatonin; Oxidants; Oxidation-Reduction; Peroxidase; Rats; Spectrophotometry, Ultraviolet | 2008 |
Optimized synthesis of the melatonin metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK).
Topics: Chlorpromazine; Chromatography, High Pressure Liquid; Horseradish Peroxidase; Hydrogen-Ion Concentration; Kynuramine; Melatonin; Osmolar Concentration; Oxidation-Reduction; Oxygen | 2008 |
Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: ameliorative potential of the melatonin metabolite, AFMK.
Topics: Analysis of Variance; Animals; Antioxidants; Brain; Cell Proliferation; Cosmic Radiation; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Immunohistochemistry; Ki-67 Antigen; Kynuramine; Lipid Peroxidation; Melatonin; Memory; Mice; Microtubule-Associated Proteins; Motor Activity; Neurogenesis; Neuropeptides; Neuroprotective Agents; Neuropsychological Tests; Oxidative Stress; Protein Carbonylation | 2008 |
Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes.
Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Kinetics; Kynuramine; Liver; Male; Melatonin; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Wistar; Serotonin; Spectrometry, Mass, Electrospray Ionization | 2008 |
MT3/QR2 melatonin binding site does not use melatonin as a substrate or a co-substrate.
Topics: Binding Sites; Humans; Kynuramine; Melatonin; Nuclear Magnetic Resonance, Biomolecular; Oxidative Stress; Quinone Reductases; Reactive Oxygen Species; Receptors, Melatonin | 2008 |
Online H/D exchange liquid chromatography as a support for the mass spectrometric identification of the oxidation products of melatonin.
Topics: Chromatography, High Pressure Liquid; Deuterium Exchange Measurement; Kynuramine; Mass Spectrometry; Melatonin; Models, Molecular; Oxidation-Reduction; Reactive Oxygen Species | 2009 |
Effect of melatonin in the antioxidant defense system in the locomotor muscles of the estuarine crab Neohelice granulata (Decapoda, Brachyura).
Topics: Animals; Antioxidants; Brachyura; Catalase; Ganglia, Invertebrate; Glutamate-Cysteine Ligase; Glutathione; Kynuramine; Lipid Peroxidation; Melatonin; Muscles; Oxidative Stress; Oxygen Consumption; Reactive Oxygen Species | 2010 |
Oxidation of melatonin by taurine chloramine.
Topics: Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hypochlorous Acid; Iodides; Kinetics; Kynuramine; Melatonin; Oxidation-Reduction; Taurine | 2010 |
Analysis of N1-acetyl-N2-formyl-5-methoxykynuramine/N1-acetyl-5-methoxy-kynuramine formation from melatonin in mice.
Topics: Acetaminophen; Animals; Antioxidants; Female; Humans; Kynuramine; Male; Melatonin; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Oxidative Stress; Principal Component Analysis | 2010 |
Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling.
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain; Cell Fractionation; Cell Line, Tumor; Indoles; Kynuramine; Melatonin; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Neuroblastoma; Propionates; Reactive Oxygen Species; Receptors, Melatonin; Statistics, Nonparametric | 2011 |
Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.
Topics: 5-Methoxytryptamine; Animals; Cell Differentiation; Cell Line; Cell Line, Tumor; Cells, Cultured; Chromatography, High Pressure Liquid; Epidermal Cells; Epidermis; Female; Fibroblasts; Humans; Keratin-10; Keratin-14; Keratinocytes; Kinetics; Kynuramine; Melanocytes; Melanoma; Melatonin; Metabolic Networks and Pathways; Serotonin; Skin; Spectrometry, Mass, Electrospray Ionization; Swine | 2013 |
Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.
Topics: 5-Methoxytryptamine; Adult; Age Factors; Aged; Aged, 80 and over; Black or African American; Cell Proliferation; Cells, Cultured; Epidermis; Female; Humans; In Vitro Techniques; Kynuramine; Male; Melanocytes; Melanoma; Melatonin; Middle Aged; Protein-Tyrosine Kinases; Sex Factors; Skin Neoplasms; White People | 2015 |
Melatonin metabolite, N(1)-acetyl-N(1)-formyl-5-methoxykynuramine (AFMK), attenuates acute pancreatitis in the rat: in vivo and in vitro studies.
Topics: Acute Disease; Aldehydes; Amylases; Animals; Anti-Inflammatory Agents; Antioxidants; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Glutathione Peroxidase; Kynuramine; Male; Malondialdehyde; Melatonin; Pancreas; Pancreatitis; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; Tumor Necrosis Factor-alpha | 2016 |
Three serum metabolite signatures for diagnosing low-grade and high-grade bladder cancer.
Topics: Biomarkers, Tumor; Case-Control Studies; Demography; Female; Humans; Inosine; Kynuramine; Male; Metabolic Networks and Pathways; Metabolomics; Multivariate Analysis; Neoplasm Grading; Principal Component Analysis; Reproducibility of Results; ROC Curve; Sphingosine; Urinary Bladder Neoplasms | 2017 |
Cortisol and melatonin in the cutaneous stress response system of fish.
Topics: Animals; Chromatography, High Pressure Liquid; Culture Media; Enzyme-Linked Immunosorbent Assay; Female; Flounder; Glucocorticoids; Hydrocortisone; Kynuramine; Male; Melanosomes; Melatonin; Skin Physiological Phenomena; Spectrometry, Fluorescence; Stress, Physiological | 2018 |
Evaluation of melatonin and AFMK levels in women with breast cancer.
Topics: Biomarkers; Breast Neoplasms; Circadian Rhythm; Female; Humans; Kynuramine; Lymphatic Metastasis; Melatonin; Middle Aged; Prognosis | 2018 |
Melatonin and its metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (afmk) enhance chemosensitivity to gemcitabine in pancreatic carcinoma cells (PANC-1).
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Gemcitabine; Humans; Kynuramine; Melatonin; Pancreatic Neoplasms | 2018 |
Melatonin and its metabolite N(1)-acetyl-N(1)-formyl-5-methoxykynuramine improve learning and memory impairment related to Alzheimer's disease in rats.
Topics: Alzheimer Disease; Animals; Antioxidants; Behavior, Animal; Brain; Glutathione Peroxidase; Kynuramine; Male; Malondialdehyde; Maze Learning; Melatonin; Neurofilament Proteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Spatial Memory; Streptozocin; Superoxide Dismutase; tau Proteins | 2020 |
The melatonin metabolite N1-acetyl-5-methoxykynuramine facilitates long-term object memory in young and aging mice.
Topics: Age Factors; Animals; Behavior, Animal; Biotransformation; Hippocampus; Kynuramine; Male; Melatonin; Memory, Long-Term; Mice, Inbred ICR; Open Field Test; Temporal Lobe; Time Factors | 2021 |