Page last updated: 2024-08-21

kynuramine and n-acetyl-5-methoxy kynurenamine

kynuramine has been researched along with n-acetyl-5-methoxy kynurenamine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.41)18.7374
1990's0 (0.00)18.2507
2000's17 (62.96)29.6817
2010's6 (22.22)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Amato, F; Kelly, RW; Seamark, RF1
Goodwin, FK; Hirata, F; Marangos, PJ; Patel, J; Paul, SM; Skolnick, P; Sondhein, D1
Claudy, D; Claustrat, B; Déchaud, H; Harthé, C; Pévet, P; Vivien-Roels, B1
Antolín, I; Hardeland, R; Mayo, JC; Poeggeler, B; Reiter, RJ; Ressmeyer, AR; Sáinz, RM; Tan, DX; Zelosko, V; Zsizsik, BK1
Campa, A; Carvalho, SR; Catalani, LH; Rodrigues, MR; Silva, SO; Ximenes, VF1
Fotso, S; Guenther, AL; Hardeland, R; Laatsch, H; Ness, H; Poeggeler, B; Ressmeyer, AR; Schmidt, SI1
Almeida, EA; Di Mascio, P; Klitzke, CF; Martinez, GR; Medeiros, MH; Onuki, J; Prado, FM1
Acuña-Castroviejo, D; Camacho, ME; Carrión, MD; Entrena, A; Escames, G; Espinosa, A; Gallo, MA; León, J; López-Cara, LC; Tapias, V; Velasco, G; Vivó, A1
Hardeland, R; Heer, C; Laatsch, H; Than, NN1
Acuña-Castroviejo, D; Camacho, E; Carrión, MD; Entrena, A; Escames, G; Espinosa, A; Gallo, MA; León, J; López, LC; Reiter, RJ; Rodríguez, MI; Tan, DX; Tapias, V1
Backhaus, C; Fadavi, A; Hardeland, R; Hess, M1
Backhaus, C; Fadavi, A; Hardeland, R1
Hardeland, R; Seever, K1
Hardeland, R; Heer, C; Laatsch, H; Nowak, A; Rahman, H; Schueth, A1
Hardeland, R; Schaefer, M1
Berger, S; Bouchet, JP; Boutin, JA; Delagrange, P; Ferry, G; Hennig, P; Marcheteau, E; Moulharat, N1
Bonnefont-Rousselot, D; Collin, F; Gardès-Albert, M; Jore, D; Marchetti, C; Yous, S1
Acuña-Castroviejo, D; Camacho, E; Carrión, MD; Entrena, A; Escames, G; Espinosa, A; Gallo, MA; López, A; López, LC; Tapias, V1
Hardeland, R; Reiter, RJ; Tan, DX1
Aeckerle, N; Hardeland, R; Kuesel, JT; Pfoertner, H1
Gonzalez, FJ; Idle, JR; Li, F; Ma, X; Niu, S; Tan, DX; Zhang, L1
Galano, A; Reiter, RJ; Tan, DX1
Hevia, D; Mayo, JC; Rodriguez-Garcia, A; Sainz, RM; Tan, DX1
Kim, TK; Li, W; Lin, Z; Reiter, RJ; Slominski, AT1
Cordaro, M; Cuzzocrea, S; Esposito, E; Paterniti, I1
Chiba, A; Hattori, A; Iwashita, H; Maruyama, Y; Matsumoto, Y; Watanabe, K1
Hardeland, R1

Reviews

5 review(s) available for kynuramine and n-acetyl-5-methoxy kynurenamine

ArticleYear
Measurement of melatonin and its metabolites: importance for the evaluation of their biological roles.
    Endocrine, 2005, Volume: 27, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Humans; Kynuramine; Mass Spectrometry; Melatonin; Reference Standards

2005
Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines.
    Journal of pineal research, 2009, Volume: 47, Issue:2

    Topics: Animals; Biogenic Amines; Humans; Indoles; Kynuramine; Melatonin; Models, Molecular

2009
On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK.
    Journal of pineal research, 2013, Volume: 54, Issue:3

    Topics: Free Radical Scavengers; Kinetics; Kynuramine; Melatonin; Models, Molecular; Thermodynamics

2013
The antioxidative property of melatonin against brain ischemia.
    Expert review of neurotherapeutics, 2016, Volume: 16, Issue:7

    Topics: Antioxidants; Brain Ischemia; Free Radicals; Humans; Kynuramine; Melatonin

2016
Melatonin, Its Metabolites and Their Interference with Reactive Nitrogen Compounds.
    Molecules (Basel, Switzerland), 2021, Jul-05, Volume: 26, Issue:13

    Topics: Animals; Antioxidants; Free Radical Scavengers; Humans; Kynuramine; Melatonin; Nitrogen Compounds; Oxidation-Reduction; Reactive Nitrogen Species

2021

Other Studies

22 other study(ies) available for kynuramine and n-acetyl-5-methoxy kynurenamine

ArticleYear
N-acetyl-5-methoxy kynurenamine, a brain metabolite of melatonin, is a potent inhibitor of prostaglandin biosynthesis.
    Biochemical and biophysical research communications, 1984, May-31, Volume: 121, Issue:1

    Topics: Animals; Aspirin; Brain; Cattle; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; In Vitro Techniques; Kynuramine; Male; Melatonin; Microsomes; Propiophenones; Seminal Vesicles; Sheep

1984
Inhibition of diazepam binding by tryptophan derivatives including melatonin and its brain metabolite N-acetyl-5-methoxy kynurenamine.
    Life sciences, 1981, Jul-20, Volume: 29, Issue:3

    Topics: Animals; Binding, Competitive; Brain; Diazepam; In Vitro Techniques; Inosine; Kinetics; Kynuramine; Melatonin; Propiophenones; Rats; Synaptosomes; Tryptophan

1981
Radioimmunoassay of N-acetyl-N-formyl-5-methoxykynuramine (AFMK): a melatonin oxidative metabolite.
    Life sciences, 2003, Aug-08, Volume: 73, Issue:12

    Topics: Animals; Diatomaceous Earth; Humans; Kynuramine; Male; Melatonin; Octanols; Oxidation-Reduction; Rabbits; Radioimmunoassay; Rats; Rats, Wistar

2003
Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction.
    Redox report : communications in free radical research, 2003, Volume: 8, Issue:4

    Topics: Animals; Antioxidants; Dinoflagellida; Free Radical Scavengers; Free Radicals; Hemin; Hydrogen Peroxide; Kynuramine; Luminescence; Melatonin; Molecular Structure; Oxidants; Oxidation-Reduction; Oxidative Stress

2003
Oxidation of melatonin and its catabolites, N1-acetyl-N2 -formyl-5-methoxykynuramine and N1-acetyl-5-methoxykynuramine, by activated leukocytes.
    Journal of pineal research, 2004, Volume: 37, Issue:3

    Topics: Catalase; Cells, Cultured; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Kinetics; Kynuramine; Leukocytes; Lipopolysaccharides; Melatonin; Neutrophil Activation; Oxidation-Reduction; Peroxidase; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Tetradecanoylphorbol Acetate

2004
Reactions of the melatonin metabolite AMK (N1-acetyl-5-methoxykynuramine) with reactive nitrogen species: formation of novel compounds, 3-acetamidomethyl-6-methoxycinnolinone and 3-nitro-AMK.
    Journal of pineal research, 2005, Volume: 39, Issue:3

    Topics: Acetamides; Kinetics; Kynuramine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Melatonin; Nitro Compounds; Pyridazines; Reactive Nitrogen Species

2005
Kynurenamines as neural nitric oxide synthase inhibitors.
    Journal of medicinal chemistry, 2005, Dec-29, Volume: 48, Issue:26

    Topics: Animals; Corpus Striatum; Enzyme Inhibitors; Kynuramine; Kynurenine 3-Monooxygenase; Molecular Conformation; Nitric Oxide Synthase Type I; Rats

2005
Reactions of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK) with the ABTS cation radical: identification of new oxidation products.
    Redox report : communications in free radical research, 2006, Volume: 11, Issue:1

    Topics: Antioxidants; Benzothiazoles; Cations; Dimerization; Free Radical Scavengers; Free Radicals; Kynuramine; Magnetic Resonance Spectroscopy; Melatonin; Molecular Structure; Nitro Compounds; Oxidation-Reduction; Reactive Nitrogen Species; Sulfonic Acids

2006
Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin.
    Journal of neurochemistry, 2006, Volume: 98, Issue:6

    Topics: Animals; Brain; Carbolines; Corpus Striatum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Harmine; In Vitro Techniques; Kinetics; Kynuramine; Male; Melatonin; Nitric Oxide Synthase Type I; Rats; Rats, Wistar

2006
N(1)-acetyl-5-methoxykynuramine contrasts with other tryptophan metabolites by a peculiar type of NO scavenging: cyclization to a cinnolinone prevents formation of unstable nitrosamines.
    Journal of pineal research, 2007, Volume: 43, Issue:1

    Topics: Acetamides; Free Radical Scavengers; Kynuramine; Nitric Oxide; Nitrosamines; Pyridazines; Tryptophan

2007
Reactions of the NO redox forms NO+, *NO and HNO (protonated NO-) with the melatonin metabolite N1-acetyl-5-methoxykynuramine.
    Journal of pineal research, 2007, Volume: 43, Issue:4

    Topics: Hydrogen-Ion Concentration; Kinetics; Kynuramine; Melatonin; Nitric Oxide Donors; Nitrites; Nitro Compounds; Nitrogen Oxides; Oxidation-Reduction; Reactive Nitrogen Species

2007
Novel pathway for N1-acetyl-5-methoxykynuramine: UVB-induced liberation of carbon monoxide from precursor N1-acetyl-N2-formyl-5-methoxykynuramine.
    Journal of pineal research, 2008, Volume: 44, Issue:4

    Topics: Carbon Monoxide; Hydroxyl Radical; Kynuramine; Melatonin; Photochemistry; Ultraviolet Rays

2008
Reactions of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK) with the tyrosine side-chain fragment, 4-ethylphenol.
    Redox report : communications in free radical research, 2008, Volume: 13, Issue:3

    Topics: Antioxidants; Cations; Electrons; Free Radical Scavengers; Free Radicals; Kinetics; Kynuramine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Melatonin; Models, Chemical; Molecular Structure; Oxidation-Reduction; Phenols; Tyrosine

2008
The melatonin metabolite N-acetyl-5-methoxykynuramine is a potent singlet oxygen scavenger.
    Journal of pineal research, 2009, Volume: 46, Issue:1

    Topics: Binding, Competitive; Free Radical Scavengers; Histidine; Kynuramine; Melatonin; Piperazines; Singlet Oxygen; Spectrum Analysis

2009
MT3/QR2 melatonin binding site does not use melatonin as a substrate or a co-substrate.
    Journal of pineal research, 2008, Volume: 45, Issue:4

    Topics: Binding Sites; Humans; Kynuramine; Melatonin; Nuclear Magnetic Resonance, Biomolecular; Oxidative Stress; Quinone Reductases; Reactive Oxygen Species; Receptors, Melatonin

2008
Online H/D exchange liquid chromatography as a support for the mass spectrometric identification of the oxidation products of melatonin.
    Journal of mass spectrometry : JMS, 2009, Volume: 44, Issue:3

    Topics: Chromatography, High Pressure Liquid; Deuterium Exchange Measurement; Kynuramine; Mass Spectrometry; Melatonin; Models, Molecular; Oxidation-Reduction; Reactive Oxygen Species

2009
Melatonin and its brain metabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice.
    Journal of neuroscience research, 2009, Volume: 87, Issue:13

    Topics: Animals; Calcium; Corpus Striatum; Cytosol; Electron Transport Complex I; Enzyme Induction; Kynuramine; Male; Melatonin; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; MPTP Poisoning; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Parkinsonian Disorders; Substantia Nigra

2009
Reactions of the melatonin metabolite N(1)-acetyl-5-methoxykynuramine with carbamoyl phosphate and related compounds.
    Journal of pineal research, 2010, Volume: 48, Issue:1

    Topics: Carbamyl Phosphate; Copper; Hydrogen Peroxide; Kynuramine; Molecular Structure

2010
Analysis of N1-acetyl-N2-formyl-5-methoxykynuramine/N1-acetyl-5-methoxy-kynuramine formation from melatonin in mice.
    Journal of pineal research, 2010, Volume: 49, Issue:2

    Topics: Acetaminophen; Animals; Antioxidants; Female; Humans; Kynuramine; Male; Melatonin; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Oxidative Stress; Principal Component Analysis

2010
Melatonin enhances photo-oxidation of 2',7'-dichlorodihydrofluorescein by an antioxidant reaction that renders N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK).
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Antioxidants; Cell Line; Cell-Free System; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen Peroxide; Kynuramine; Light; Melatonin; Oxidants; Oxidation-Reduction; Oxidative Stress

2014
N1-Acetyl-5-Methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects.
    Endocrinology, 2015, Volume: 156, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Black or African American; Cell Line; Cell Line, Tumor; Cell Proliferation; Epidermis; Female; Humans; In Vitro Techniques; Keratinocytes; Kynuramine; Male; Melanocytes; Melanoma; Melatonin; Middle Aged; Skin Neoplasms; White People

2015
The melatonin metabolite N1-acetyl-5-methoxykynuramine facilitates long-term object memory in young and aging mice.
    Journal of pineal research, 2021, Volume: 70, Issue:1

    Topics: Age Factors; Animals; Behavior, Animal; Biotransformation; Hippocampus; Kynuramine; Male; Melatonin; Memory, Long-Term; Mice, Inbred ICR; Open Field Test; Temporal Lobe; Time Factors

2021