Page last updated: 2024-08-21

kynuramine and melatonin

kynuramine has been researched along with melatonin in 72 studies

Research

Studies (72)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.78)	18.7374
1990's	1 (1.39)	18.2507
2000's	47 (65.28)	29.6817
2010's	17 (23.61)	24.3611
2020's	5 (6.94)	2.80

Authors

Authors	Studies
Amato, F; Kelly, RW; Seamark, RF	1
Goodwin, FK; Hirata, F; Marangos, PJ; Patel, J; Paul, SM; Skolnick, P; Sondhein, D	1
Balzer, I; Behrmann, G; Fuhrberg, B; Hardeland, R; Meyer, TJ; Poeggeler, B; Reiter, RJ; Uría, H; Wolf, R	1
Limson, J; Manchester, LC; Plummer, BF; Qi, W; Reiter, RJ; Tan, DX; Weintraub, ST	1
Burkhardt, S; Cabrera, J; Hardeland, R; Karbownik, M; Reiter, RJ; Tan, DX	1
Burkhardt, S; Hardeland, R; Huo, YS; Kohen, R; Manchester, LC; Mayo, JC; Reiter, RJ; Sainz, RM; Shohami, E; Tan, DX	1
Campa, A; Catalani, LH; Ximenes, VF	1
Allegra, M; Avellone, G; Ceraulo, L; D'Arpa, D; Livrea, MA; Tesoriere, L	1
Hardeland, R; Niebergall, R; Poeggeler, B; Zelosko, V	1
Campa, A; Henrique Catalani, L; Rodrigues, MR; Rodriguez, D; Russo, M	1
Hardeland, R; Lopez-Burillo, S; Manchester, LC; Mayo, JC; Poeggeler, B; Reiter, RJ; Sainz, RM; Tan, DX	1
Claudy, D; Claustrat, B; Déchaud, H; Harthé, C; Pévet, P; Vivien-Roels, B	1
de Almeida, EA; de Medeiros, MH; Di Mascio, P; Klitzke, CF; Martinez, GR	1
Blashko, EL; Filatova, EV; Orlov, AA; Pozdeyev, NV; Rozov, SV; Volkova, AV; Zhloba, AR	1
Antolín, I; Hardeland, R; Mayo, JC; Poeggeler, B; Reiter, RJ; Ressmeyer, AR; Sáinz, RM; Tan, DX; Zelosko, V; Zsizsik, BK	1
Almeida, EA; Di Mascio, P; Klitzke, CF; Martinez, GR; Medeiros, MH	1
Coto-Montes, A; Hardeland, R; Poeggeler, B	1
Campa, A; Carvalho, SR; Catalani, LH; Rodrigues, MR; Silva, SO; Ximenes, VF	1
Amarante-Mendes, GP; Bueno-da-Silva, AE; Campa, A; Rodrigues, MR; Silva, SO; Ximenes, VF	1
Behrends, A; Grube, S; Haldar, C; Hardeland, R; Ness, H; Poeggeler, B	1
Almeida, EA; Di Mascio, P; Medeiros, MH; Onuki, J	1
Hardeland, R; Leon, J; Mayo, JC; Reiter, RJ; Rodriguez, C; Sainz, RM; Tan, DX	1
Hardeland, R; Leon, J; Manchester, LC; Mayo, JC; Poeggeler, B; Reiter, RJ; Sainz, RM; Tan, DX	1
Campa, A; Catalani, LH; Kettle, AJ; Maghzal, GJ; Rodrigues, MR; Silva, SO; Ximenes, VF	1
Fotso, S; Guenther, AL; Hardeland, R; Laatsch, H; Ness, H; Poeggeler, B; Ressmeyer, AR; Schmidt, SI	1
Campa, A; Catalani, LH; Livramento, JA; Silva, SO; Ximenes, VF	1
Almeida, EA; Di Mascio, P; Klitzke, CF; Martinez, GR; Medeiros, MH; Onuki, J; Prado, FM	1
Campa, A; Carvalho, SR; Okada, SS; Silva, SO; Ximenes, VF	1
Hardeland, R; Heer, C; Laatsch, H; Than, NN	1
Acuña-Castroviejo, D; Camacho, E; Carrión, MD; Entrena, A; Escames, G; Espinosa, A; Gallo, MA; León, J; López, LC; Reiter, RJ; Rodríguez, MI; Tan, DX; Tapias, V	1
Flores, LJ; Manchester, LC; Reiter, RJ; Tan, DX; Terron, MP	1
Di Mascio, P; Manchester, LC; Martinez, GR; Prado, FM; Reiter, RJ; Tan, DX	1
Budu, A; Bueno, VB; Catalani, LH; Garcia, CR; Peres, R	1
Bueno, VB; Catalani, LH; de Oliveira, GH; Fernandes, JR; Machado, RG; Ximenes, VF	1
Anzai, K; Manda, K; Ueno, M	2
Catalá, A; Fagali, N	1
Daya, S; Glass, BD; Maharaj, DS	1
Backhaus, C; Fadavi, A; Hardeland, R	1
Hardeland, R; Seever, K	1
Cabello, C; de Menezes, ML; Fernandes, JR; Rodrigues, AP; Ximenes, VF	1
Ducrocq, C; Peyrot, F	1
Ximenes, VF	1
Hardeland, R; Heer, C; Laatsch, H; Nowak, A; Rahman, H; Schueth, A	1
Hardeland, R; Schaefer, M	1
Antonova, M; Korik, E; Semak, I; Slominski, A; Wortsman, J	1
Berger, S; Bouchet, JP; Boutin, JA; Delagrange, P; Ferry, G; Hennig, P; Marcheteau, E; Moulharat, N	1
Bonnefont-Rousselot, D; Collin, F; Gardès-Albert, M; Jore, D; Marchetti, C; Yous, S	1
Acuña-Castroviejo, D; Camacho, E; Carrión, MD; Entrena, A; Escames, G; Espinosa, A; Gallo, MA; López, A; López, LC; Tapias, V	1
Hardeland, R; Reiter, RJ; Tan, DX	1
Caldas, SS; Cruz, BP; Geihs, MA; Maciel, FE; Monserrat, JM; Nery, LE; Primel, EG; Vargas, MA	1
Carvalho, DA; Fernandes, JR; Padovan, CZ; Ximenes, VF	1
Gonzalez, FJ; Idle, JR; Li, F; Ma, X; Niu, S; Tan, DX; Zhang, L	1
Arendash, GW; Bradshaw, PC; Buzzeo, R; Cao, C; Copes, N; Dragicevic, N; Jin, J; Mamcarz, M; O'Neal-Moffitt, G; Olcese, JM; Tan, J	1
Galano, A; Reiter, RJ; Tan, DX	1
Fischer, TW; Janjetovic, Z; Kim, TK; Kleszczynski, K; Li, W; Lin, Z; Reiter, RJ; Slominski, AT; Sweatman, T	1
Li, C; Li, F; Li, G; Ma, X; Tan, DX	1
Hanna, S; Janjetovic, Z; Jarrett, SG; Kim, TK; Nahmias, ZP; Reiter, RJ; Slominski, AT	1
Kim, TK; Li, W; Lin, Z; Slominski, AT; Tidwell, WJ	1
Hevia, D; Mayo, JC; Rodriguez-Garcia, A; Sainz, RM; Tan, DX	1
Kim, TK; Li, W; Lin, Z; Reiter, RJ; Slominski, AT	1
Bonior, J; Goralska, M; Jastrzebska, M; Jaworek, J; Leja-Szpak, A; Link-Lenczowski, P; Nawrot-Porabka, K; Pierzchalski, P	2
Cordaro, M; Cuzzocrea, S; Esposito, E; Paterniti, I	1
Bonior, J; Czech, U; Goralska, M; Jaworek, J; Kot, M; Pierzchalski, P; Reiter, RJ; Szklarczyk, J; Tomaszewska, R	1
Gozdowska, M; Kalamarz-Kubiak, H; Kulczykowska, E; Sokołowska, E	1
Bordin-Junior, NA; de Almeida, EA; de Campos Zuccari, DAP; de Castro, TB	1
Chen, N; Deng, Y; Gong, C; Li, L; Liu, X; Rong, K; Yang, R; Zhao, G; Zheng, H	1
Chiba, A; Hattori, A; Iwashita, H; Maruyama, Y; Matsumoto, Y; Watanabe, K	1
Hardeland, R	1
Gozdowska, M; Kulczykowska, E; Pomianowski, K; Sokołowska, E	1
Chiba, A; Iwashita, H; Sano, M	1

Reviews

9 review(s) available for kynuramine and melatonin

Article	Year
Circadian rhythms, oxidative stress, and antioxidative defense mechanisms. Chronobiology international, 2003, Volume: 20, Issue:6 Topics: Animals; Antioxidants; Biological Clocks; Circadian Rhythm; Humans; Isoenzymes; Kynuramine; Melatonin; Mitochondria; Neoplasms; Nuclear Proteins; Oxidants; Oxidation-Reduction; Oxidative Stress; Period Circadian Proteins; Quinone Reductases; Transcription Factors	2003
Measurement of melatonin and its metabolites: importance for the evaluation of their biological roles. Endocrine, 2005, Volume: 27, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Humans; Kynuramine; Mass Spectrometry; Melatonin; Reference Standards	2005
One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? Journal of pineal research, 2007, Volume: 42, Issue:1 Topics: Animals; Biological Availability; Humans; Kynuramine; Melatonin	2007
Melatonin: new places in therapy. Bioscience reports, 2007, Volume: 27, Issue:6 Topics: Animals; Antioxidants; Circadian Rhythm; Humans; Kynuramine; Melatonin; Neuroprotective Agents; Pineal Gland; Reactive Oxygen Species	2007
Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species. Journal of pineal research, 2008, Volume: 45, Issue:3 Topics: Animals; Antioxidants; Carcinogens; Humans; Kynuramine; Kynurenine; Melatonin; Mutagens; Nitric Oxide Donors; Nitrogen Dioxide; Nitroso Compounds; Oxidation-Reduction; Peroxynitrous Acid; Reactive Nitrogen Species; Reactive Oxygen Species; Serotonin; Stress, Physiological; Tryptophan	2008
Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. Journal of pineal research, 2009, Volume: 47, Issue:2 Topics: Animals; Biogenic Amines; Humans; Indoles; Kynuramine; Melatonin; Models, Molecular	2009
On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK. Journal of pineal research, 2013, Volume: 54, Issue:3 Topics: Free Radical Scavengers; Kinetics; Kynuramine; Melatonin; Models, Molecular; Thermodynamics	2013
The antioxidative property of melatonin against brain ischemia. Expert review of neurotherapeutics, 2016, Volume: 16, Issue:7 Topics: Antioxidants; Brain Ischemia; Free Radicals; Humans; Kynuramine; Melatonin	2016
Melatonin, Its Metabolites and Their Interference with Reactive Nitrogen Compounds. Molecules (Basel, Switzerland), 2021, Jul-05, Volume: 26, Issue:13 Topics: Animals; Antioxidants; Free Radical Scavengers; Humans; Kynuramine; Melatonin; Nitrogen Compounds; Oxidation-Reduction; Reactive Nitrogen Species	2021

Other Studies

63 other study(ies) available for kynuramine and melatonin

Article	Year
N-acetyl-5-methoxy kynurenamine, a brain metabolite of melatonin, is a potent inhibitor of prostaglandin biosynthesis. Biochemical and biophysical research communications, 1984, May-31, Volume: 121, Issue:1 Topics: Animals; Aspirin; Brain; Cattle; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; In Vitro Techniques; Kynuramine; Male; Melatonin; Microsomes; Propiophenones; Seminal Vesicles; Sheep	1984
Inhibition of diazepam binding by tryptophan derivatives including melatonin and its brain metabolite N-acetyl-5-methoxy kynurenamine. Life sciences, 1981, Jul-20, Volume: 29, Issue:3 Topics: Animals; Binding, Competitive; Brain; Diazepam; In Vitro Techniques; Inosine; Kinetics; Kynuramine; Melatonin; Propiophenones; Rats; Synaptosomes; Tryptophan	1981
On the primary functions of melatonin in evolution: mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals. Journal of pineal research, 1995, Volume: 18, Issue:2 Topics: 5-Methoxytryptamine; Animals; Biological Evolution; Dinoflagellida; Free Radical Scavengers; Hydrogen-Ion Concentration; Kynuramine; Light; Melatonin; Monoamine Oxidase; Oxidants, Photochemical; Photoperiod; Signal Transduction	1995
Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation. Free radical biology & medicine, 2000, Volume: 29, Issue:11 Topics: Catalase; Free Radical Scavengers; Glutathione Peroxidase; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Kynuramine; Magnetic Resonance Spectroscopy; Melatonin	2000
DNA oxidatively damaged by chromium(III) and H(2)O(2) is protected by the antioxidants melatonin, N(1)-acetyl-N(2)-formyl-5-methoxykynuramine, resveratrol and uric acid. The international journal of biochemistry & cell biology, 2001, Volume: 33, Issue:8 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Chromatography, High Pressure Liquid; Chromium Compounds; Deoxyguanosine; DNA Damage; Hydrogen Peroxide; Kynuramine; Melatonin; Molecular Structure; Resveratrol; Stilbenes; Uric Acid	2001
N1-acetyl-N2-formyl-5-methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:12 Topics: 8-Hydroxy-2'-Deoxyguanosine; Amyloid beta-Peptides; Animals; Antioxidants; Cell Death; Cells, Cultured; Chelating Agents; Deoxyguanosine; Ferrous Compounds; Free Radicals; Glutamic Acid; Hydrogen Peroxide; Kynuramine; Lipid Peroxidation; Liver; Melatonin; Metals, Heavy; Models, Biological; Neurons; Peptide Fragments; Rats	2001
Oxidation of melatonin and tryptophan by an HRP cycle involving compound III. Biochemical and biophysical research communications, 2001, Sep-14, Volume: 287, Issue:1 Topics: Chromatography, High Pressure Liquid; Horseradish Peroxidase; Hydrogen Peroxide; Kynuramine; Melatonin; Oxidation-Reduction; Tryptophan	2001
Oxidation of melatonin by oxoferryl hemoglobin: a mechanistic study. Free radical research, 2001, Volume: 35, Issue:6 Topics: Animals; Cattle; Chlorine; Gas Chromatography-Mass Spectrometry; Hemoglobins; Hydrogen Peroxide; Kinetics; Kynuramine; Magnetic Resonance Spectroscopy; Melatonin; Methemoglobin; Oxidation-Reduction; Oxides; Spectrophotometry, Ultraviolet; Time Factors	2001
Oxidation of melatonin by carbonate radicals and chemiluminescence emitted during pyrrole ring cleavage. Journal of pineal research, 2003, Volume: 34, Issue:1 Topics: Carbonates; Kynuramine; Luminescent Measurements; Melatonin; Oxidation-Reduction; Pyrroles	2003
Interferon-gamma independent oxidation of melatonin by macrophages. Journal of pineal research, 2003, Volume: 34, Issue:1 Topics: Animals; Azides; Hydrogen Peroxide; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynuramine; Macrophages; Melatonin; Mice; Mice, Knockout; Oxidation-Reduction; Peroxidase; Tetradecanoylphorbol Acetate; Tryptophan; Tryptophan Oxygenase	2003
Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical. Journal of pineal research, 2003, Volume: 34, Issue:4 Topics: Antioxidants; Ascorbic Acid; Benzothiazoles; Cations; Chromans; Chromatography, High Pressure Liquid; Electrochemistry; Free Radical Scavengers; Free Radicals; Glutathione; Hydrogen-Ion Concentration; Kynuramine; Mechanics; Melatonin; NAD; NADP; Sulfonic Acids	2003
Radioimmunoassay of N-acetyl-N-formyl-5-methoxykynuramine (AFMK): a melatonin oxidative metabolite. Life sciences, 2003, Aug-08, Volume: 73, Issue:12 Topics: Animals; Diatomaceous Earth; Humans; Kynuramine; Male; Melatonin; Octanols; Oxidation-Reduction; Rabbits; Radioimmunoassay; Rats; Rats, Wistar	2003
Oxidation of melatonin by singlet molecular oxygen (O2(1deltag)) produces N1-acetyl-N2-formyl-5-methoxykynurenine. Journal of pineal research, 2003, Volume: 35, Issue:2 Topics: Chromatography, High Pressure Liquid; Kinetics; Kynuramine; Mass Spectrometry; Melatonin; Oxidation-Reduction; Singlet Oxygen	2003
N1-acetyl-N2-formyl-5-methoxykynuramine is a product of melatonin oxidation in rats. Journal of pineal research, 2003, Volume: 35, Issue:4 Topics: Animals; Kynuramine; Melatonin; Oxidation-Reduction; Rats; Retina	2003
Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction. Redox report : communications in free radical research, 2003, Volume: 8, Issue:4 Topics: Animals; Antioxidants; Dinoflagellida; Free Radical Scavengers; Free Radicals; Hemin; Hydrogen Peroxide; Kynuramine; Luminescence; Melatonin; Molecular Structure; Oxidants; Oxidation-Reduction; Oxidative Stress	2003
Synthesis of internal labeled standards of melatonin and its metabolite N1-acetyl-N2-formyl-5-methoxykynuramine for their quantification using an on-line liquid chromatography-electrospray tandem mass spectrometry system. Journal of pineal research, 2004, Volume: 36, Issue:1 Topics: Biochemistry; Calibration; Chromatography, Liquid; Humans; Kynuramine; Melatonin; Spectrometry, Mass, Electrospray Ionization	2004
Oxidation of melatonin and its catabolites, N1-acetyl-N2 -formyl-5-methoxykynuramine and N1-acetyl-5-methoxykynuramine, by activated leukocytes. Journal of pineal research, 2004, Volume: 37, Issue:3 Topics: Catalase; Cells, Cultured; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Kinetics; Kynuramine; Leukocytes; Lipopolysaccharides; Melatonin; Neutrophil Activation; Oxidation-Reduction; Peroxidase; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Tetradecanoylphorbol Acetate	2004
Neutrophils as a specific target for melatonin and kynuramines: effects on cytokine release. Journal of neuroimmunology, 2004, Volume: 156, Issue:1-2 Topics: Analysis of Variance; Cells, Cultured; Cytokines; Humans; Kynuramine; Melatonin; Neutrophils; Oxidation-Reduction	2004
Photocatalytic actions of the pesticide metabolite 2-hydroxyquinoxaline: destruction of antioxidant vitamins and biogenic amines - implications of organic redox cycling. Redox report : communications in free radical research, 2004, Volume: 9, Issue:5 Topics: Amines; Antioxidants; Ascorbic Acid; Catalysis; Catecholamines; Dimerization; Dopamine; Ethanol; Free Radical Scavengers; Kynuramine; Light; Melatonin; Models, Chemical; Oxidants; Oxidation-Reduction; Oxygen; Piperazines; Quinoxalines; Serotonin; Spectrophotometry; Time Factors; Ultraviolet Rays; Vitamin E; Vitamins	2004
Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol. Journal of pineal research, 2005, Volume: 38, Issue:2 Topics: Aminolevulinic Acid; Antioxidants; DNA; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Kynuramine; Melatonin; Photosensitizing Agents; Porphyria, Acute Intermittent; Quercetin; Resveratrol; Stilbenes	2005
Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages. Journal of neuroimmunology, 2005, Volume: 165, Issue:1-2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Indoles; Kynuramine; Lipopolysaccharides; Macrophage Activation; Macrophages; Melatonin; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Superoxides	2005
Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin. Journal of pineal research, 2005, Volume: 39, Issue:2 Topics: Animals; Catalase; Cell-Free System; Humans; Hydrogen Peroxide; Kynuramine; Melatonin; NAD; Nicotinamide Mononucleotide; Oxyhemoglobins; PC12 Cells; Rats; Superoxide Dismutase	2005
Superoxide-dependent oxidation of melatonin by myeloperoxidase. The Journal of biological chemistry, 2005, Nov-18, Volume: 280, Issue:46 Topics: Animals; Antioxidants; Catalase; Catalysis; Cattle; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dimerization; Dose-Response Relationship, Drug; Free Radicals; Heme; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Kynuramine; Liver; Mass Spectrometry; Melatonin; Models, Chemical; Neutrophils; Oxygen; Ozone; Peroxidase; Protein Binding; Superoxides; Taurine; Time Factors; Xanthine Oxidase	2005
Reactions of the melatonin metabolite AMK (N1-acetyl-5-methoxykynuramine) with reactive nitrogen species: formation of novel compounds, 3-acetamidomethyl-6-methoxycinnolinone and 3-nitro-AMK. Journal of pineal research, 2005, Volume: 39, Issue:3 Topics: Acetamides; Kinetics; Kynuramine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Melatonin; Nitro Compounds; Pyridazines; Reactive Nitrogen Species	2005
High concentrations of the melatonin metabolite, N1-acetyl-N2-formyl-5-methoxykynuramine, in cerebrospinal fluid of patients with meningitis: a possible immunomodulatory mechanism. Journal of pineal research, 2005, Volume: 39, Issue:3 Topics: Adjuvants, Immunologic; Biomarkers; Chromatography, High Pressure Liquid; Humans; Kynuramine; Melatonin; Meningitis	2005
Melatonin and its kynurenin-like oxidation products affect the microbicidal activity of neutrophils. Microbes and infection, 2006, Volume: 8, Issue:2 Topics: Cells, Cultured; Humans; Hypochlorous Acid; Kynuramine; Melatonin; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Phagocytosis; Staphylococcus aureus	2006
Reactions of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK) with the ABTS cation radical: identification of new oxidation products. Redox report : communications in free radical research, 2006, Volume: 11, Issue:1 Topics: Antioxidants; Benzothiazoles; Cations; Dimerization; Free Radical Scavengers; Free Radicals; Kynuramine; Magnetic Resonance Spectroscopy; Melatonin; Molecular Structure; Nitro Compounds; Oxidation-Reduction; Reactive Nitrogen Species; Sulfonic Acids	2006
Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin. Journal of neurochemistry, 2006, Volume: 98, Issue:6 Topics: Animals; Brain; Carbolines; Corpus Striatum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Harmine; In Vitro Techniques; Kinetics; Kynuramine; Male; Melatonin; Nitric Oxide Synthase Type I; Rats; Rats, Wistar	2006
Novel rhythms of N1-acetyl-N2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2007, Volume: 21, Issue:8 Topics: Adaptation, Physiological; Circadian Rhythm; Eichhornia; Kynuramine; Light; Melatonin; Phytotherapy; Plant Physiological Phenomena	2007
N1-acetyl-N2-formyl-5-methoxykynuramine modulates the cell cycle of malaria parasites. Journal of pineal research, 2007, Volume: 42, Issue:3 Topics: Animals; Cell Cycle; Erythrocytes; Kynuramine; Melatonin; Mice; Mice, Inbred BALB C; Plasmodium chabaudi; Plasmodium falciparum	2007
The effect of pH on horseradish peroxidase-catalyzed oxidation of melatonin: production of N1-acetyl-N2-5-methoxykynuramine versus radical-mediated degradation. Journal of pineal research, 2007, Volume: 42, Issue:3 Topics: Horseradish Peroxidase; Hydrogen-Ion Concentration; Kynuramine; Melatonin; Oxidation-Reduction	2007
AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. Journal of pineal research, 2007, Volume: 42, Issue:4 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Cerebral Cortex; Comet Assay; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Kynuramine; Lipid Peroxidation; Male; Melatonin; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; X-Rays	2007
The effect of melatonin and structural analogues on the lipid peroxidation of triglycerides enriched in omega-3 polyunsaturated fatty acids. Life sciences, 2007, Jul-04, Volume: 81, Issue:4 Topics: 5-Methoxytryptamine; Benzene Derivatives; Biphenyl Compounds; Butylated Hydroxytoluene; Cell-Free System; Docosahexaenoic Acids; Fatty Acids, Omega-3; Free Radical Scavengers; Kynuramine; Lipid Peroxidation; Lipids; Luminescent Measurements; Melatonin; Oxidation-Reduction; Picrates; Reactive Oxygen Species; Serotonin; Thiobarbituric Acid Reactive Substances; Triglycerides; Tryptophan	2007
Reactions of the NO redox forms NO+, NO and HNO (protonated NO-) with the melatonin metabolite N1-acetyl-5-methoxykynuramine. Journal of pineal research, 2007, Volume: 43, Issue:4* Topics: Hydrogen-Ion Concentration; Kinetics; Kynuramine; Melatonin; Nitric Oxide Donors; Nitrites; Nitro Compounds; Nitrogen Oxides; Oxidation-Reduction; Reactive Nitrogen Species	2007
Novel pathway for N1-acetyl-5-methoxykynuramine: UVB-induced liberation of carbon monoxide from precursor N1-acetyl-N2-formyl-5-methoxykynuramine. Journal of pineal research, 2008, Volume: 44, Issue:4 Topics: Carbon Monoxide; Hydroxyl Radical; Kynuramine; Melatonin; Photochemistry; Ultraviolet Rays	2008
The co-catalytic effect of chlorpromazine on peroxidase-mediated oxidation of melatonin: enhanced production of N1-acetyl-N2-formyl-5-methoxykynuramine. Journal of pineal research, 2008, Volume: 44, Issue:2 Topics: Animals; Antioxidants; Antipsychotic Agents; Chlorpromazine; Humans; Kynuramine; Melatonin; Oxidants; Oxidation-Reduction; Peroxidase; Rats; Spectrophotometry, Ultraviolet	2008
Optimized synthesis of the melatonin metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK). Journal of pineal research, 2008, Volume: 45, Issue:3 Topics: Chlorpromazine; Chromatography, High Pressure Liquid; Horseradish Peroxidase; Hydrogen-Ion Concentration; Kynuramine; Melatonin; Osmolar Concentration; Oxidation-Reduction; Oxygen	2008
Reactions of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK) with the tyrosine side-chain fragment, 4-ethylphenol. Redox report : communications in free radical research, 2008, Volume: 13, Issue:3 Topics: Antioxidants; Cations; Electrons; Free Radical Scavengers; Free Radicals; Kinetics; Kynuramine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Melatonin; Models, Chemical; Molecular Structure; Oxidation-Reduction; Phenols; Tyrosine	2008
Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: ameliorative potential of the melatonin metabolite, AFMK. Journal of pineal research, 2008, Volume: 45, Issue:4 Topics: Analysis of Variance; Animals; Antioxidants; Brain; Cell Proliferation; Cosmic Radiation; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Immunohistochemistry; Ki-67 Antigen; Kynuramine; Lipid Peroxidation; Melatonin; Memory; Mice; Microtubule-Associated Proteins; Motor Activity; Neurogenesis; Neuropeptides; Neuroprotective Agents; Neuropsychological Tests; Oxidative Stress; Protein Carbonylation	2008
The melatonin metabolite N-acetyl-5-methoxykynuramine is a potent singlet oxygen scavenger. Journal of pineal research, 2009, Volume: 46, Issue:1 Topics: Binding, Competitive; Free Radical Scavengers; Histidine; Kynuramine; Melatonin; Piperazines; Singlet Oxygen; Spectrum Analysis	2009
Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes. Journal of pineal research, 2008, Volume: 45, Issue:4 Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Kinetics; Kynuramine; Liver; Male; Melatonin; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Wistar; Serotonin; Spectrometry, Mass, Electrospray Ionization	2008
MT3/QR2 melatonin binding site does not use melatonin as a substrate or a co-substrate. Journal of pineal research, 2008, Volume: 45, Issue:4 Topics: Binding Sites; Humans; Kynuramine; Melatonin; Nuclear Magnetic Resonance, Biomolecular; Oxidative Stress; Quinone Reductases; Reactive Oxygen Species; Receptors, Melatonin	2008
Online H/D exchange liquid chromatography as a support for the mass spectrometric identification of the oxidation products of melatonin. Journal of mass spectrometry : JMS, 2009, Volume: 44, Issue:3 Topics: Chromatography, High Pressure Liquid; Deuterium Exchange Measurement; Kynuramine; Mass Spectrometry; Melatonin; Models, Molecular; Oxidation-Reduction; Reactive Oxygen Species	2009
Melatonin and its brain metabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice. Journal of neuroscience research, 2009, Volume: 87, Issue:13 Topics: Animals; Calcium; Corpus Striatum; Cytosol; Electron Transport Complex I; Enzyme Induction; Kynuramine; Male; Melatonin; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; MPTP Poisoning; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Parkinsonian Disorders; Substantia Nigra	2009
Effect of melatonin in the antioxidant defense system in the locomotor muscles of the estuarine crab Neohelice granulata (Decapoda, Brachyura). General and comparative endocrinology, 2010, Mar-01, Volume: 166, Issue:1 Topics: Animals; Antioxidants; Brachyura; Catalase; Ganglia, Invertebrate; Glutamate-Cysteine Ligase; Glutathione; Kynuramine; Lipid Peroxidation; Melatonin; Muscles; Oxidative Stress; Oxygen Consumption; Reactive Oxygen Species	2010
Oxidation of melatonin by taurine chloramine. Journal of pineal research, 2010, Volume: 49, Issue:2 Topics: Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hypochlorous Acid; Iodides; Kinetics; Kynuramine; Melatonin; Oxidation-Reduction; Taurine	2010
Analysis of N1-acetyl-N2-formyl-5-methoxykynuramine/N1-acetyl-5-methoxy-kynuramine formation from melatonin in mice. Journal of pineal research, 2010, Volume: 49, Issue:2 Topics: Acetaminophen; Animals; Antioxidants; Female; Humans; Kynuramine; Male; Melatonin; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Oxidative Stress; Principal Component Analysis	2010
Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling. Journal of pineal research, 2011, Volume: 51, Issue:1 Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain; Cell Fractionation; Cell Line, Tumor; Indoles; Kynuramine; Melatonin; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Neuroblastoma; Propionates; Reactive Oxygen Species; Receptors, Melatonin; Statistics, Nonparametric	2011
Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:7 Topics: 5-Methoxytryptamine; Animals; Cell Differentiation; Cell Line; Cell Line, Tumor; Cells, Cultured; Chromatography, High Pressure Liquid; Epidermal Cells; Epidermis; Female; Fibroblasts; Humans; Keratin-10; Keratin-14; Keratinocytes; Kinetics; Kynuramine; Melanocytes; Melanoma; Melatonin; Metabolic Networks and Pathways; Serotonin; Skin; Spectrometry, Mass, Electrospray Ionization; Swine	2013
A novel enzyme-dependent melatonin metabolite in humans. Journal of pineal research, 2013, Volume: 54, Issue:1 Topics: Adult; Humans; Kynuramine; Melatonin; Metabolomics	2013
Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes. Journal of pineal research, 2014, Volume: 57, Issue:1 Topics: Cell Line; DNA Damage; Humans; Keratinocytes; Kynuramine; Melatonin; Serotonin; Ultraviolet Rays	2014
Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro. Molecular and cellular endocrinology, 2015, Mar-15, Volume: 404 Topics: 5-Methoxytryptamine; Adult; Age Factors; Aged; Aged, 80 and over; Black or African American; Cell Proliferation; Cells, Cultured; Epidermis; Female; Humans; In Vitro Techniques; Kynuramine; Male; Melanocytes; Melanoma; Melatonin; Middle Aged; Protein-Tyrosine Kinases; Sex Factors; Skin Neoplasms; White People	2015
Melatonin enhances photo-oxidation of 2',7'-dichlorodihydrofluorescein by an antioxidant reaction that renders N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK). PloS one, 2014, Volume: 9, Issue:10 Topics: Antioxidants; Cell Line; Cell-Free System; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen Peroxide; Kynuramine; Light; Melatonin; Oxidants; Oxidation-Reduction; Oxidative Stress	2014
N1-Acetyl-5-Methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects. Endocrinology, 2015, Volume: 156, Issue:5 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Black or African American; Cell Line; Cell Line, Tumor; Cell Proliferation; Epidermis; Female; Humans; In Vitro Techniques; Keratinocytes; Kynuramine; Male; Melanocytes; Melanoma; Melatonin; Middle Aged; Skin Neoplasms; White People	2015
Kynuramines induce overexpression of heat shock proteins in pancreatic cancer cells via 5-hydroxytryptamine and MT1/MT2 receptors. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2015, Volume: 66, Issue:5 Topics: Cell Line, Tumor; Heat-Shock Proteins; Humans; Ketanserin; Kynuramine; Melatonin; Pancreatic Neoplasms; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Serotonin; Tropanes; Tryptamines; Tryptophan	2015
Melatonin metabolite, N(1)-acetyl-N(1)-formyl-5-methoxykynuramine (AFMK), attenuates acute pancreatitis in the rat: in vivo and in vitro studies. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2016, Volume: 67, Issue:3 Topics: Acute Disease; Aldehydes; Amylases; Animals; Anti-Inflammatory Agents; Antioxidants; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Glutathione Peroxidase; Kynuramine; Male; Malondialdehyde; Melatonin; Pancreas; Pancreatitis; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; Tumor Necrosis Factor-alpha	2016
Cortisol and melatonin in the cutaneous stress response system of fish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2018, Volume: 218 Topics: Animals; Chromatography, High Pressure Liquid; Culture Media; Enzyme-Linked Immunosorbent Assay; Female; Flounder; Glucocorticoids; Hydrocortisone; Kynuramine; Male; Melanosomes; Melatonin; Skin Physiological Phenomena; Spectrometry, Fluorescence; Stress, Physiological	2018
Evaluation of melatonin and AFMK levels in women with breast cancer. Endocrine, 2018, Volume: 62, Issue:1 Topics: Biomarkers; Breast Neoplasms; Circadian Rhythm; Female; Humans; Kynuramine; Lymphatic Metastasis; Melatonin; Middle Aged; Prognosis	2018
Melatonin and its metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (afmk) enhance chemosensitivity to gemcitabine in pancreatic carcinoma cells (PANC-1). Pharmacological reports : PR, 2018, Volume: 70, Issue:6 Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Gemcitabine; Humans; Kynuramine; Melatonin; Pancreatic Neoplasms	2018
Melatonin and its metabolite N(1)-acetyl-N(1)-formyl-5-methoxykynuramine improve learning and memory impairment related to Alzheimer's disease in rats. Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:2 Topics: Alzheimer Disease; Animals; Antioxidants; Behavior, Animal; Brain; Glutathione Peroxidase; Kynuramine; Male; Malondialdehyde; Maze Learning; Melatonin; Neurofilament Proteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Spatial Memory; Streptozocin; Superoxide Dismutase; tau Proteins	2020
The melatonin metabolite N1-acetyl-5-methoxykynuramine facilitates long-term object memory in young and aging mice. Journal of pineal research, 2021, Volume: 70, Issue:1 Topics: Age Factors; Animals; Behavior, Animal; Biotransformation; Hippocampus; Kynuramine; Male; Melatonin; Memory, Long-Term; Mice, Inbred ICR; Open Field Test; Temporal Lobe; Time Factors	2021
Melatonin and cortisol as components of the cutaneous stress response system in fish: Response to oxidative stress. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2022, Volume: 268 Topics: Animals; Antioxidants; Hydrocortisone; Kynuramine; Mammals; Melatonin; Oxidative Stress	2022
Effects of endogenous and exogenous N-acetyl-5-methoxy kynuramine on object recognition memory in male C3H mice. Hormones and behavior, 2023, Volume: 150 Topics: Animals; Antioxidants; Dementia; Kynuramine; Male; Melatonin; Mice; Mice, Inbred C3H; Mice, Inbred ICR	2023