kwd 2131 has been researched along with histamine in 3 studies
*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]
*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]
| Studies (kwd 2131) | Trials (kwd 2131) | Recent Studies (post-2010) (kwd 2131) | Studies (histamine) | Trials (histamine) | Recent Studies (post-2010) (histamine) |
|---|---|---|---|---|---|
| 16 | 12 | 0 | 37,718 | 1,372 | 3,457 |
| Protein | Taxonomy | kwd 2131 (IC50) | histamine (IC50) |
|---|---|---|---|
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.1585 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.1585 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hegardt, B; Löwhagen, O; Svedmyr, N | 1 |
| Pegelow, KO; Strandberg, K | 1 |
| Granerus, G; Hegardt, B; Löwhagen, O; Svedmyr, N | 1 |
3 trial(s) available for kwd 2131 and histamine
| Article | Year |
|---|---|
Histamine-induced bronchospasm. Its reproducibility and usage in clinical evaluation of the sub-threshold bronchodilating dose of a new beta-agonist, KWD 2131.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Histamine; Humans; Male; Middle Aged; Terbutaline | 1980 |
Evaluation of the bronchodilating and antiallergic properties of a beta-adrenoceptor stimulant, KWD 2131, in asthmatic patients.
Topics: Adrenergic beta-Antagonists; Adult; Allergens; Asthma; Bronchodilator Agents; Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Heart Rate; Histamine; Humans; Hypersensitivity; Male; Peak Expiratory Flow Rate; Random Allocation; Terbutaline; Tremor | 1980 |
The protective property of equipotent bronchodilating doses of inhaled KWD 2131 and terbutaline against allergen-induced bronchospasm.
Topics: Administration, Intranasal; Adult; Allergens; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Agents; Female; Forced Expiratory Volume; Histamine; Humans; Male; Terbutaline | 1982 |