kw 5092 has been researched along with neostigmine in 7 studies
| Studies (kw 5092) | Trials (kw 5092) | Recent Studies (post-2010) (kw 5092) | Studies (neostigmine) | Trials (neostigmine) | Recent Studies (post-2010) (neostigmine) |
|---|---|---|---|---|---|
| 14 | 0 | 0 | 5,020 | 454 | 637 |
| Protein | Taxonomy | kw 5092 (IC50) | neostigmine (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Electrophorus electricus (electric eel) | 2.54 | |
| Cholinesterase | Homo sapiens (human) | 0.45 | |
| Acetylcholinesterase | Homo sapiens (human) | 1.1 | |
| Cholinesterase | Equus caballus (horse) | 2.93 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishii, A; Karasawa, A; Kishibayashi, N | 1 |
| Karasawa, A; Kishibayashi, N | 3 |
| Ichikawa, S; Ishii, A; Karasawa, A; Kishibayashi, N; Kitazawa, T; Shuto, K; Tomaru, A | 1 |
| Ichikawa, S; Ishii, A; Kitazawa, T; Nonaka, H; Obase, H; Sasho, S; Shuto, K; Yoshizaki, R | 1 |
| Karasawa, A; Kishibayashi, N; Suzuki, M; Yokoyama, T | 1 |
7 other study(ies) available for kw 5092 and neostigmine
| Article | Year |
|---|---|
Inhibitory effects of KW-5092, a novel gastroprokinetic agent, on the activity of acetylcholinesterase in guinea pig ileum.
Topics: Acetylthiocholine; Animals; Benzamides; Benzyl Compounds; Butyrylthiocholine; Cholinesterase Inhibitors; Guinea Pigs; Hydrolysis; Ileum; Imidazoles; In Vitro Techniques; Kinetics; Male; Muscle Proteins; Neostigmine; Nitriles | 1994 |
Stimulating effects of KW-5092, a novel gastroprokinetic agent, on the gastric emptying, small intestinal propulsion and colonic propulsion in rats.
Topics: Animals; Colon; Dose-Response Relationship, Drug; Gastric Emptying; Imidazoles; Intestines; Male; Metoclopramide; Neostigmine; Nitriles; Rats; Rats, Sprague-Dawley | 1995 |
Enhancement by KW-5092, a novel gastroprokinetic agent, of the gastrointestinal motor activity in dogs.
Topics: Acetylcholine; Animals; Blood Pressure; Cholinesterase Inhibitors; Colon; Dogs; Dose-Response Relationship, Drug; Duodenum; Female; Gastrointestinal Motility; Ileum; Imidazoles; Injections, Intravenous; Male; Neostigmine; Nitriles; Pyloric Antrum; Ranitidine; Respiration | 1994 |
Synthesis of 2-imidazolidinylidenepropanedinitrile derivatives as stimulators of gastrointestinal motility.
Topics: Animals; Cholinesterase Inhibitors; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Ileum; Imidazoles; Male; Molecular Structure; Muscle Contraction; Neostigmine; Nitriles; Nitrogen; Rabbits; Ranitidine; Structure-Activity Relationship | 1993 |
Effects of KW-5092, a novel gastroprokinetic agent, on intestinal water and electrolyte transport in rats.
Topics: Animals; Bisacodyl; Cathartics; Cholinesterase Inhibitors; Colon; Dose-Response Relationship, Drug; Electrolytes; Gastrointestinal Agents; Gastrointestinal Motility; Imidazoles; Intestinal Absorption; Jejunum; Male; Neostigmine; Nitriles; Rats; Rats, Sprague-Dawley; Water | 1995 |
Effect of KW-5092, novel gastroprokinetic agent, on the peristalsis in the isolated guinea pig ileum.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Domperidone; Dopamine Antagonists; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Male; Muscarinic Antagonists; Neostigmine; Nitriles; Peristalsis | 1997 |
Effects of KW-5092 on antroduodenal coordination and gastric emptying in guinea-pigs.
Topics: Administration, Oral; Animals; Cholinesterase Inhibitors; Cisapride; Drug Interactions; Duodenum; Gastric Emptying; Gastrointestinal Agents; Guinea Pigs; Imidazoles; Male; Neostigmine; Nitriles | 1998 |