Compounds > kt 5823
Page last updated: 2024-09-02

kt 5823 and ro 31-8220

kt 5823 has been researched along with ro 31-8220 in 3 studies

Compound Research Comparison

Studies
(kt 5823)		Trials
(kt 5823)		Recent Studies (post-2010)
(kt 5823)		Studies
(ro 31-8220)		Trials
(ro 31-8220)		Recent Studies (post-2010) (ro 31-8220)
317059587164

Protein Interaction Comparison

ProteinTaxonomykt 5823 (IC50)ro 31-8220 (IC50)
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)0.008
Serine/threonine-protein kinase 10Homo sapiens (human)0.099
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)0.9
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.01
Protein kinase C alpha typeHomo sapiens (human)0.033
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)0.0068
Ribosomal protein S6 kinase beta-1Homo sapiens (human)0.015
Mitogen-activated protein kinase kinase kinase 8Homo sapiens (human)9.95
Glycogen synthase kinase-3 betaHomo sapiens (human)0.0116
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)0.01
Protein kinase C beta typeRattus norvegicus (Norway rat)0.01
Homeodomain-interacting protein kinase 1Homo sapiens (human)0.621
NAD-dependent protein deacetylase sirtuin-2Homo sapiens (human)0.875
Mitogen-activated protein kinase kinase kinase kinase 1Homo sapiens (human)0.0529
NAD-dependent protein deacetylase sirtuin-1Homo sapiens (human)3.9
Serine/threonine-protein kinase VRK1Homo sapiens (human)0.743
NAD-dependent protein deacetylase sirtuin-3, mitochondrialHomo sapiens (human)3.7
Serine/threonine-protein kinase TBK1Homo sapiens (human)0.656

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fukui, H; Horio, S; Kawakami, N; Miyoshi, K1
Fukui, H; Horio, S; Izumi, N; Kawakami, N; Miyoshi, K; Wakayama, Y1
Arandarcikaite, O; Barauskaite, J; Borutaite, V; Brown, GC; Jekabsone, A; Morkuniene, R1

Other Studies

3 other study(ies) available for kt 5823 and ro 31-8220

ArticleYear
Inhibition of histamine H1 receptor downregulation by KT5823, a protein kinase G inhibitor.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbazoles; CHO Cells; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activators; Histamine; Indoles; Isoquinolines; Protein Kinase C; Receptors, Histamine H1; Sulfonamides; Thionucleotides; Time Factors

2003
Histamine H1 receptor down-regulation mediated by M3 muscarinic acetylcholine receptor subtype.
    Journal of pharmacological sciences, 2004, Volume: 95, Issue:4

    Topics: Animals; Atropine; Carbachol; Carbazoles; CHO Cells; Cholinergic Agonists; Cricetinae; Cricetulus; Down-Regulation; Histamine H1 Antagonists; Indoles; Inositol Phosphates; Muscarinic Antagonists; Phosphorylation; Protein Kinase C; Pyrilamine; Radioligand Assay; Receptor, Muscarinic M3; Receptors, Histamine H1; Signal Transduction; Time Factors

2004
Nitric oxide protects the heart from ischemia-induced apoptosis and mitochondrial damage via protein kinase G mediated blockage of permeability transition and cytochrome c release.
    Journal of biomedical science, 2009, Aug-11, Volume: 16

    Topics: Animals; Apoptosis; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Cytochromes c; Indoles; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Ischemia; Nitric Oxide; Nitric Oxide Donors; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Triazenes

2009