Compounds > kt 5823
Page last updated: 2024-09-02

kt 5823 and ouabain

kt 5823 has been researched along with ouabain in 4 studies

Compound Research Comparison

Studies
(kt 5823)		Trials
(kt 5823)		Recent Studies (post-2010)
(kt 5823)		Studies
(ouabain)		Trials
(ouabain)		Recent Studies (post-2010) (ouabain)
31705916,35772747

Protein Interaction Comparison

ProteinTaxonomykt 5823 (IC50)ouabain (IC50)
STAT3, partialHomo sapiens (human)1.154
Kruppel-like factor 5Homo sapiens (human)0.0832
Sodium/potassium-transporting ATPase subunit alpha-1 Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-1Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit alpha-1 Rattus norvegicus (Norway rat)4.3
Sodium/potassium-transporting ATPase subunit alpha-2Rattus norvegicus (Norway rat)0.17
Sodium/potassium-transporting ATPase subunit alpha-3 Rattus norvegicus (Norway rat)0.031
Sodium/potassium-transporting ATPase subunit beta-1 Rattus norvegicus (Norway rat)1.1263
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.1646
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.097
Sodium/potassium-transporting ATPase subunit alpha-3Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-2Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit alpha-2Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-3Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit gammaHomo sapiens (human)6
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)5.8
Sodium/potassium-transporting ATPase subunit alpha-4Homo sapiens (human)6
Sodium/potassium-transporting ATPase subunit beta-3Rattus norvegicus (Norway rat)0.0018
Sodium/potassium-transporting ATPase subunit alpha-4Rattus norvegicus (Norway rat)0.0031

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McKee, M; Nathanson, JA; Scanlon, C; Scavone, C1
Gloor, SM; Pontiggia, L; Winterhalter, K1
Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L1
Chanda, D; Gupta, PK; Joshi, P; Krishna, AV; Mishra, SK; Prakash, VR; Sharma, B; Singh, TU1

Other Studies

4 other study(ies) available for kt 5823 and ouabain

ArticleYear
Atrial natriuretic peptide modulates sodium and potassium-activated adenosine triphosphatase through a mechanism involving cyclic GMP and cyclic GMP-dependent protein kinase.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Alkaloids; Amiloride; Animals; Atrial Natriuretic Factor; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Indoles; Kidney Medulla; Male; Nitric Oxide; Ouabain; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase

1995
Inhibition of Na,K-ATPase activity by cGMP is isoform-specific in brain endothelial cells.
    FEBS letters, 1998, Oct-09, Volume: 436, Issue:3

    Topics: Alkaloids; Animals; Carbazoles; Cerebrovascular Circulation; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Inhibitors; Indoles; Isoenzymes; Kinetics; Mice; Nitric Oxide; Ouabain; Polymerase Chain Reaction; Rats; Recombinant Proteins; Sodium-Potassium-Exchanging ATPase

1998
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
    Circulation research, 2004, Oct-01, Volume: 95, Issue:7

    Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate

2004
Role of low ouabain-sensitive isoform of Na+-K+-ATPase in the regulation of basal tone and agonist-induced contractility in ovine pulmonary artery.
    Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:2

    Topics: Animals; Carbazoles; Cardiotonic Agents; Dose-Response Relationship, Drug; In Vitro Techniques; Isoenzymes; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Phenylephrine; Pulmonary Artery; Serotonin; Sheep; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents

2008