Page last updated: 2024-09-02

kt 5823 and methylene blue

kt 5823 has been researched along with methylene blue in 8 studies

Compound Research Comparison

Studies
(kt 5823)
Trials
(kt 5823)
Recent Studies (post-2010)
(kt 5823)
Studies
(methylene blue)
Trials
(methylene blue)
Recent Studies (post-2010) (methylene blue)
31705911,0673944,258

Protein Interaction Comparison

ProteinTaxonomykt 5823 (IC50)methylene blue (IC50)
Chain E, Fibrin beta chainHomo sapiens (human)9.253
integrase, partialHuman immunodeficiency virus 11.958
lens epithelium-derived growth factor p75Homo sapiens (human)1.958
Apoptotic peptidase activating factor 1Homo sapiens (human)15.5
neutrophil cytosol factor 1Homo sapiens (human)0.39
caspase-9 isoform alpha precursorHomo sapiens (human)17
caspase-3 isoform a preproproteinHomo sapiens (human)17
Glutathione reductasePlasmodium falciparum 3D76.4
Amyloid-beta precursor proteinHomo sapiens (human)0.5
Microtubule-associated protein tauHomo sapiens (human)2.2333
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.5
Amine oxidase [flavin-containing] AHomo sapiens (human)0.07
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.5
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.5

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's5 (62.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kanagawa, A; Morita, T; Shimada, Y; Ueki, H1
Joyner, RW; Kumar, R; Namiki, T1
Kaye, DM; Kelly, RA; Wiviott, SD1
Caldarera, CM; Clô, C; Facchini, A; Fattori, M; Flamigni, F; Giordano, E; Pignatti, C; Stefanelli, C; Tantini, B1
Amarillo, Y; Moreno, H; Nadal, MS; Rudy, B; Vega-Saenz de Miera, E1
Minami, K; Nakashima, Y; Sata, T; Segawa, K; Shiga, Y; Shigematsu, A; Shiraishi, M1
Canals, S; Casarejos, MJ; de Bernardo, S; Mena, MA; Rodríguez-Martín, E1
De Laurentiis, A; Dees, W; Fernández-Solari, J; McCann, SM; Mohn, C; Prestifilippo, JP; Rettori, V1

Other Studies

8 other study(ies) available for kt 5823 and methylene blue

ArticleYear
Stimulation of nitric oxide-cyclic GMP pathway by L-arginine increases the release of hepatic lipase from cultured rat hepatocytes.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:10

    Topics: Alkaloids; Animals; Arginine; Carbazoles; Cyclic GMP; Enzyme Inhibitors; Indoles; Lipase; Liver; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats

1996
Effects of cGMP on L-type calcium current of adult and newborn rabbit ventricular cells.
    Cardiovascular research, 1997, Volume: 33, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Aminoquinolines; Animals; Animals, Newborn; Calcium; Calcium Channels; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Female; Glutathione; Guanylate Cyclase; Indoles; Male; Methylene Blue; Myocardium; Nitroso Compounds; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Rabbits; S-Nitrosoglutathione; Thionucleotides; Time Factors

1997
Activation of nitric oxide synthase (NOS3) by mechanical activity alters contractile activity in a Ca2+-independent manner in cardiac myocytes: role of troponin I phosphorylation.
    Biochemical and biophysical research communications, 1999, Mar-16, Volume: 256, Issue:2

    Topics: Actin Cytoskeleton; Alkaloids; Animals; Calcium; Carbazoles; Cardiac Pacing, Artificial; Cell Size; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Heart Ventricles; In Vitro Techniques; Indoles; Male; Methylene Blue; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Phosphorylation; Rats; Rats, Sprague-Dawley; Troponin I; Ventricular Function

1999
Polyamines, NO and cGMP mediate stimulation of DNA synthesis by tumor necrosis factor and lipopolysaccharide in chick embryo cardiomyocytes.
    Cardiovascular research, 2001, Feb-01, Volume: 49, Issue:2

    Topics: Alkaloids; Aminoquinolines; Animals; Carbazoles; Cells, Cultured; Chick Embryo; Cyclic GMP; DNA; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Lipopolysaccharides; Methylene Blue; Myocardium; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Kinase Inhibitors; Stimulation, Chemical; Tumor Necrosis Factor-alpha

2001
Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase.
    The Journal of physiology, 2001, Feb-01, Volume: 530, Issue:Pt 3

    Topics: Alkaloids; Animals; Carbazoles; CHO Cells; Cricetinae; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Membrane Potentials; Methylene Blue; Neuropeptides; Nitric Oxide; Nitric Oxide Donors; Okadaic Acid; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinases; Protein Phosphatase 2; Recombinant Proteins; Shaw Potassium Channels; Transfection

2001
Inhibitory effects of nicorandil on rat mesangial cell proliferation via the protein kinase G pathway.
    Nephron, 2001, Volume: 87, Issue:3

    Topics: Alkaloids; Animals; Carbazoles; Cell Division; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Glomerular Mesangium; Guanylate Cyclase; Indoles; Male; Methylene Blue; Nicorandil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Signal Transduction; Thymidine

2001
Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: implications for Parkinson's disease.
    Journal of neurochemistry, 2001, Volume: 79, Issue:6

    Topics: Alkaloids; Aminoquinolines; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Buthionine Sulfoximine; Carbazoles; Cell Division; Cells, Cultured; Cyclic GMP-Dependent Protein Kinases; Dopamine; Enzyme Inhibitors; Free Radicals; Glutathione; Glutathione Synthase; Guanylate Cyclase; Homeostasis; Hydrazines; Indoles; Mesencephalon; Methylene Blue; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nucleic Acid Synthesis Inhibitors; Parkinson Disease; Penicillamine; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase

2001
Effect of manganese on luteinizing hormone-releasing hormone secretion in adult male rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 97, Issue:1

    Topics: Age Factors; Animals; Carbazoles; Chlorides; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; Gonadotropin-Releasing Hormone; Guanylate Cyclase; Hemoglobins; Hypothalamus; In Vitro Techniques; Indoles; Male; Manganese Compounds; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sex Factors; Signal Transduction

2007