Compounds > kt 5823
Page last updated: 2024-09-02

kt 5823 and dinoprostone

kt 5823 has been researched along with dinoprostone in 4 studies

Compound Research Comparison

Studies
(kt 5823)		Trials
(kt 5823)		Recent Studies (post-2010)
(kt 5823)		Studies
(dinoprostone)		Trials
(dinoprostone)		Recent Studies (post-2010) (dinoprostone)
31705929,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomykt 5823 (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frank, HJ; Hu, RM; Levin, ER; Nazario, B; Pedram, A; Prins, BA; Weber, MA1
Cunha, FQ; Ferreira, SH; Sachs, D1
Brito, GA; Cunha, FQ; Ferreira, SH; Lotufo, CM; Ribeiro, RA; Sachs, D; Vale, ML1
Beyer, C; Etgen, AM; Garcia-Juárez, M; Gómez-Camarillo, MA; Gómora-Arrati, P; González-Flores, O; Lima-Hernández, FJ1

Other Studies

4 other study(ies) available for kt 5823 and dinoprostone

ArticleYear
Prostaglandin E2 and prostacyclin inhibit the production and secretion of endothelin from cultured endothelial cells.
    The Journal of biological chemistry, 1994, Apr-22, Volume: 269, Issue:16

    Topics: Alkaloids; Aminoquinolines; Animals; Aorta; Carbazoles; Cattle; Cell Division; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Cyclic GMP; Dinoprostone; DNA; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Epoprostenol; Indoles; Kinetics; Muscle, Smooth, Vascular; Protein Biosynthesis; Protein Kinase Inhibitors; RNA, Messenger; SRS-A; Thymidine; Transfection

1994
Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Mar-09, Volume: 101, Issue:10

    Topics: Adenosine Triphosphate; Analgesics; Animals; Arginine; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Indoles; Male; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Signal Transduction

2004
Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K channel pathway.
    The European journal of neuroscience, 2006, Volume: 24, Issue:4

    Topics: Adenosine Triphosphate; Analgesia; Analgesics; Animals; Arginine; Bucladesine; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Ganglia, Spinal; Glyburide; Indoles; KATP Channels; Male; Neurons; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Pain Measurement; Pertussis Toxin; Potassium Channels, Inwardly Rectifying; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Tolbutamide

2006
Nitric oxide and ERK/MAPK mediation of estrous behavior induced by GnRH, PGE2 and db-cAMP in rats.
    Physiology & behavior, 2009, Mar-23, Volume: 96, Issue:4-5

    Topics: Analysis of Variance; Animals; Carbazoles; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Estrous Cycle; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Gonadotropin-Releasing Hormone; Guanylate Cyclase; Injections, Intraventricular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Sexual Behavior, Animal; Signal Transduction; Statistics, Nonparametric

2009