Compounds > kt 5823
Page last updated: 2024-09-02

kt 5823 and colforsin

kt 5823 has been researched along with colforsin in 12 studies

Compound Research Comparison

Studies
(kt 5823)		Trials
(kt 5823)		Recent Studies (post-2010)
(kt 5823)		Studies
(colforsin)		Trials
(colforsin)		Recent Studies (post-2010) (colforsin)
31705913,460461,298

Protein Interaction Comparison

ProteinTaxonomykt 5823 (IC50)colforsin (IC50)
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)1.729
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.041
Adenylate cyclase type 1Homo sapiens (human)0.0955

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's8 (66.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Komalavilas, P; Lincoln, TM1
Polte, T; Schröder, H1
Giebisch, G; Lu, M; MacGregor, GG; Wang, W1
Bader, B; Burkhardt, M; Butt, E; Gambaryan, S; Glazova, M; Heermeier, K; Lincoln, TM; Palmetshofer, A; Vollkommer, T; Walter, U1
Deth, RC; Sharma, A; Waly, M1
Bełtowski, J; Górny, D; Marciniak, A; Wójcicka, G1
Barman, SA; Han, G; White, RE; Zhu, S1
Libersan, D; Merhi, Y; Rousseau, G1
Delbecque, JP; Gautron, F; Manière, G; Vanhems, E1
Burrell, HE; Durham, B; Fraser, WD; Gallagher, JA; McCreavy, DT; Mehat, S; Sharpe, GR; Simpson, AW1
Chen, YX; Fleischmann, B; Hescheler, J; Ji, G; Miao, L; Wang, M; Yin, WX; Yuan, Q1
Canella, R; Fesce, R; Martini, M; Rossi, ML; Rubbini, G1

Other Studies

12 other study(ies) available for kt 5823 and colforsin

ArticleYear
Phosphorylation of the inositol 1,4,5-trisphosphate receptor. Cyclic GMP-dependent protein kinase mediates cAMP and cGMP dependent phosphorylation in the intact rat aorta.
    The Journal of biological chemistry, 1996, Sep-06, Volume: 271, Issue:36

    Topics: Alkaloids; Angiotensin II; Animals; Aorta; Calcium Channels; Carbazoles; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Male; Nitroprusside; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thionucleotides; Time Factors

1996
Cyclic AMP mediates endothelial protection by nitric oxide.
    Biochemical and biophysical research communications, 1998, Oct-20, Volume: 251, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Alkaloids; Animals; Carbazoles; Cattle; Cell Line; Cell Survival; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic N-Oxides; Dideoxyadenosine; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Indoles; Kinetics; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Pulmonary Artery; Pyrroles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha

1998
Extracellular ATP inhibits the small-conductance K channel on the apical membrane of the cortical collecting duct from mouse kidney.
    The Journal of general physiology, 2000, Volume: 116, Issue:2

    Topics: Adenosine Triphosphate; Affinity Labels; Alkaloids; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Extracellular Space; Indoles; Ion Channel Gating; Kidney Tubules, Collecting; Membrane Potentials; Mice; Mice, Inbred C57BL; Naphthalenes; NG-Nitroarginine Methyl Ester; Okadaic Acid; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Small-Conductance Calcium-Activated Potassium Channels; Thionucleotides; Uridine Triphosphate

2000
KT5823 inhibits cGMP-dependent protein kinase activity in vitro but not in intact human platelets and rat mesangial cells.
    The Journal of biological chemistry, 2000, Oct-27, Volume: 275, Issue:43

    Topics: Alkaloids; Animals; Blood Platelets; Carbazoles; Cattle; Cell Adhesion Molecules; Colforsin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Glomerular Mesangium; Humans; Indoles; Isoquinolines; Microfilament Proteins; Nitric Oxide; Phosphoproteins; Phosphorylation; Rats; Sulfonamides

2000
Protein kinase C regulates dopamine D4 receptor-mediated phospholipid methylation.
    European journal of pharmacology, 2001, Sep-14, Volume: 427, Issue:2

    Topics: Alkaloids; Benzophenanthridines; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Methylation; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phenanthridines; Phorbol 12,13-Dibutyrate; Phospholipids; Protein Kinase C; Receptors, Dopamine D2; Receptors, Dopamine D4; Thionucleotides; Tumor Cells, Cultured

2001
The opposite effects of cyclic AMP-protein kinase a signal transduction pathway on renal cortical and medullary Na+,K+-ATPase activity.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2002, Volume: 53, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Animals; Arachidonic Acid; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Indoles; Kidney Cortex; Kidney Medulla; Male; Okadaic Acid; Phosphodiesterase Inhibitors; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Sodium-Potassium-Exchanging ATPase

2002
cAMP activates BKCa channels in pulmonary arterial smooth muscle via cGMP-dependent protein kinase.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 284, Issue:6

    Topics: Alkaloids; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Hypertrophy, Right Ventricular; Indoles; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Potassium Channels, Calcium-Activated; Pulmonary Artery; Rats; Rats, Inbred Strains; Thionucleotides; Vasodilator Agents

2003
Differential regulation of P-selectin expression by protein kinase A and protein kinase G in thrombin-stimulated human platelets.
    Thrombosis and haemostasis, 2003, Volume: 89, Issue:2

    Topics: Adenylyl Cyclases; Alkaloids; Blood Platelets; Carbazoles; Cell Adhesion; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Isoquinolines; Neutrophils; P-Selectin; Phosphorylation; Platelet Activation; Protein Processing, Post-Translational; Second Messenger Systems; Sulfonamides; Thrombin

2003
Inhibition of ovarian steroidogenesis by cyclic GMP in a fly.
    The Journal of endocrinology, 2003, Volume: 177, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Alkaloids; Animals; Brain; Calcium Channels; Carbazoles; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Diptera; Ecdysteroids; Female; Indoles; Organ Culture Techniques; Ovary; Phosphodiesterase Inhibitors; Quinazolines; Signal Transduction; Stimulation, Chemical

2003
Potentiation of ATP- and bradykinin-induced [Ca2+]c responses by PTHrP peptides in the HaCaT cell line.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Bradykinin; Calcium; Carbazoles; Cell Division; Cell Line; Colforsin; Cyclic AMP; Cyclic GMP; Drug Synergism; Humans; Indoles; Keratinocytes; Parathyroid Hormone-Related Protein; Peptide Fragments; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Signal Transduction

2008
Atrial natriuretic peptide regulates Ca channel in early developmental cardiomyocytes.
    PloS one, 2010, Jan-22, Volume: 5, Issue:1

    Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atrial Natriuretic Factor; Base Sequence; Calcium Channels, L-Type; Carbazoles; Cells, Cultured; Colforsin; DNA Primers; Embryonic Stem Cells; Enzyme Inhibitors; Fluorescent Antibody Technique; Heart; Isoproterenol; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Reverse Transcriptase Polymerase Chain Reaction

2010
Forskolin and protein kinase inhibitors differentially affect hair cell potassium currents and transmitter release at the cytoneural junction in the isolated frog labyrinth.
    Neuroscience, 2017, 08-15, Volume: 357

    Topics: Action Potentials; Amphibian Proteins; Animals; Carbazoles; Colforsin; Excitatory Postsynaptic Potentials; Hair Cells, Ampulla; Isoquinolines; Miniature Postsynaptic Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Rana esculenta; Sulfonamides; Tissue Culture Techniques

2017