kt 5823 has been researched along with 8-bromo cyclic adenosine monophosphate in 16 studies
| Studies (kt 5823) | Trials (kt 5823) | Recent Studies (post-2010) (kt 5823) | Studies (8-bromo cyclic adenosine monophosphate) | Trials (8-bromo cyclic adenosine monophosphate) | Recent Studies (post-2010) (8-bromo cyclic adenosine monophosphate) |
|---|---|---|---|---|---|
| 317 | 0 | 59 | 3,707 | 5 | 198 |
| Protein | Taxonomy | kt 5823 (IC50) | 8-bromo cyclic adenosine monophosphate (IC50) |
|---|---|---|---|
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | 7.7 | |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | 7.7 | |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | 7.7 | |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | 7.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 12 (75.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Polte, T; Schröder, H | 1 |
| Geiger, JD; Guo, ZH; Mattson, MP | 1 |
| Jo, H; Komalavilas, P; Lincoln, TM; Shah, PK | 1 |
| Matsunobu, T; Schacht, J | 1 |
| Gorodeski, GI | 1 |
| Burnett, JC; Eilam, Y; Fixler, R; Hasin, Y; Nir, A; Zhang, DF | 1 |
| Adragna, NC; Di Fulvio, M; Lauf, PK; Lincoln, TM | 1 |
| Curcio, F; Doi, SQ; Lagranha, C; Perrella, G; Sellitti, DF | 1 |
| Jernigan, NL; Resta, TC; Walker, BR | 1 |
| Fukui, H; Horio, S; Kawakami, N; Miyoshi, K | 1 |
| Keung, W; Man, RY; Vanhoutte, PM | 1 |
| Liu, L; Xu, J | 1 |
| Anand-Srivastava, MB; Bassil, M | 1 |
| Harada, N; Kubo, N; Shen, J; Takeda-Nakazawa, H; Yamashita, T; Zenner, HP | 1 |
| Anand-Srivastava, MB; Arejian, M; Li, Y | 1 |
| Miao, Y; Wang, Z; Yang, XL; Zhang, M; Zhao, WJ | 1 |
16 other study(ies) available for kt 5823 and 8-bromo cyclic adenosine monophosphate
| Article | Year |
|---|---|
Cyclic AMP mediates endothelial protection by nitric oxide.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Alkaloids; Animals; Carbazoles; Cattle; Cell Line; Cell Survival; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic N-Oxides; Dideoxyadenosine; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Indoles; Kinetics; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Pulmonary Artery; Pyrroles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 1998 |
Secreted form of amyloid precursor protein enhances basal glucose and glutamate transport and protects against oxidative impairment of glucose and glutamate transport in synaptosomes by a cyclic GMP-mediated mechanism.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apoptosis; Biological Transport; Carbazoles; Cerebral Cortex; Cyclic GMP; Enzyme Inhibitors; Female; Ferrous Compounds; Glucose; Glutamic Acid; Indoles; Lipid Peroxidation; Neurons; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; Synapses; Synaptosomes; Tritium | 1999 |
Activation of mitogen-activated protein kinase pathways by cyclic GMP and cyclic GMP-dependent protein kinase in contractile vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Aorta; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Pyrroles; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Thionucleotides; Time Factors; Transfection; Tumor Necrosis Factor-alpha | 1999 |
Nitric oxide/cyclic GMP pathway attenuates ATP-evoked intracellular calcium increase in supporting cells of the guinea pig cochlea.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Alkaloids; Animals; Biological Transport; Calcium; Carbazoles; Cell Survival; Cochlea; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Homeostasis; In Vitro Techniques; Indoles; Nitric Oxide; Protein Kinase Inhibitors; Protein Kinases; Thionucleotides | 2000 |
cGMP-dependent ADP depolymerization of actin mediates estrogen increase in cervical epithelial permeability.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Actins; Adenosine Diphosphate; Alkaloids; Aminoquinolines; Carbazoles; Cell Membrane Permeability; Cells, Cultured; Cervix Mucus; Cervix Uteri; Cyclic GMP; Enzyme Inhibitors; Epithelial Cells; Estradiol; Estrogen Antagonists; Female; Humans; In Vitro Techniques; Indoles; Nitric Oxide; Nitroprusside; Polymers; Ribose; Tamoxifen; Vasodilator Agents | 2000 |
C-type natriuretic peptide has a negative inotropic effect on cardiac myocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Calcium; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Depression, Chemical; Dose-Response Relationship, Drug; Guanylate Cyclase; Indoles; Myocardial Contraction; Myocardium; Natriuretic Peptide, C-Type; Polysaccharides; Radioligand Assay; Rats; Receptors, Atrial Natriuretic Factor | 2001 |
Protein kinase G regulates potassium chloride cotransporter-4 [corrected] expression in primary cultures of rat vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Aorta; Brain; Carbazoles; Carrier Proteins; Catalytic Domain; Cells, Cultured; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation; Indoles; K Cl- Cotransporters; Kidney; Kinetics; Muscle, Smooth, Vascular; Protein Isoforms; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters; Transcription, Genetic; Transfection | 2001 |
Atrial natriuretic factor and C-type natriuretic peptide induce retraction of human thyrocytes in monolayer culture via guanylyl cyclase receptors.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Analysis of Variance; Animals; Atrial Natriuretic Factor; Carbazoles; Cell Count; Cell Division; Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanylate Cyclase; Humans; Indoles; Microscopy, Phase-Contrast; Natriuretic Peptide, C-Type; Receptors, Atrial Natriuretic Factor; Signal Transduction; Thyroid Gland | 2002 |
Pulmonary PKG-1 is upregulated following chronic hypoxia.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Carbazoles; Chronic Disease; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Immunohistochemistry; Indoles; Lung; Nitric Oxide; Platelet Aggregation Inhibitors; Polycythemia; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Thionucleotides; Up-Regulation; Vascular Resistance; Vasodilation | 2003 |
Inhibition of histamine H1 receptor downregulation by KT5823, a protein kinase G inhibitor.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbazoles; CHO Cells; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activators; Histamine; Indoles; Isoquinolines; Protein Kinase C; Receptors, Histamine H1; Sulfonamides; Thionucleotides; Time Factors | 2003 |
Acute impairment of contractile responses by 17beta-estradiol is cAMP and protein kinase G dependent in vascular smooth muscle cells of the porcine coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenylyl Cyclase Inhibitors; Animals; Carbazoles; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Drug Interactions; Estradiol; Indoles; Isometric Contraction; Isoproterenol; Muscle, Smooth, Vascular; Swine; Thionucleotides; Time Factors | 2005 |
The role of calcium desensitization in vascular hyporeactivity and its regulation after hemorrhagic shock in the rat.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blood Vessels; Calcium; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Indoles; Insulin; Male; Marine Toxins; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Oxazoles; Perfusion; Protein Kinase Inhibitors; Rats; Rats, Wistar; Shock, Hemorrhagic; Staurosporine; Tetradecanoylphorbol Acetate | 2005 |
Cyclic GMP modulates the expression of Gi protein and adenylyl cyclase signaling in vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Aorta; Blood Pressure; Carbazoles; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Muscle, Smooth, Vascular; Rats; Signal Transduction | 2007 |
Hyposmotic stimulation-induced nitric oxide production in outer hair cells of the guinea pig cochlea.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Carbazoles; Cell Size; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Gadolinium; Guanylate Cyclase; Guinea Pigs; Hair Cells, Auditory, Outer; Hypotonic Solutions; Indoles; Kinetics; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Organ of Corti; Osmotic Pressure; Phorbol Esters; Potassium; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Sodium Chloride; Suramin; TRPV Cation Channels | 2007 |
Nitric oxide attenuates the expression of natriuretic peptide receptor C and associated adenylyl cyclase signaling in aortic vascular smooth muscle cells: role of MAPK.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Aorta; Carbazoles; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; GTP-Binding Protein alpha Subunits, Gi-Go; MAP Kinase Signaling System; Metalloporphyrins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Phosphorylation; Protein Kinase Inhibitors; Quinoxalines; Rats; Receptors, Atrial Natriuretic Factor; S-Nitroso-N-Acetylpenicillamine | 2009 |
Melatonin potentiates glycine currents through a PLC/PKC signalling pathway in rat retinal ganglion cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bridged-Ring Compounds; Calcium; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Egtazic Acid; Estrenes; Glycine; Guanosine Diphosphate; Indoles; Isoquinolines; Male; Maleimides; Melatonin; Norbornanes; Pertussis Toxin; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT2; Retinal Ganglion Cells; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Tetrahydronaphthalenes; Thiocarbamates; Thiones; Type C Phospholipases | 2010 |