Page last updated: 2024-09-02

kt 5823 and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

kt 5823 has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 4 studies

Compound Research Comparison

Studies
(kt 5823)
Trials
(kt 5823)
Recent Studies (post-2010)
(kt 5823)
Studies
(2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)
Trials
(2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)
Recent Studies (post-2010) (2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)
3170594,82351,810

Protein Interaction Comparison

ProteinTaxonomykt 5823 (IC50)2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one (IC50)
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)4
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)4
Chain A, Methyltransferase WbddEscherichia coli68
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)1.6413
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHomo sapiens (human)1.4218
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.002
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)9.614
Cytochrome P450 1A2Homo sapiens (human)1
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)1.6
Serine/threonine-protein kinase pim-1Homo sapiens (human)3.364
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)1.6
Casein kinase II subunit alpha'Homo sapiens (human)6.9
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)3.1638
5-hydroxytryptamine receptor 2AHomo sapiens (human)2.796
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.002
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)2.3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformBos taurus (cattle)3.7533
Type-1 angiotensin II receptorOryctolagus cuniculus (rabbit)0.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)1.4593
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Mus musculus (house mouse)0.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)1.2922
Serine/threonine-protein kinase mTORHomo sapiens (human)4.1638
Serine/threonine-protein kinase mTORRattus norvegicus (Norway rat)2.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)2.4845
Glycogen synthase kinase-3 betaHomo sapiens (human)8.1
Serine/threonine-protein kinase PLK1Homo sapiens (human)2.05
Casein kinase II subunit betaHomo sapiens (human)6.9
Casein kinase II subunit alphaHomo sapiens (human)6.9
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)1.32
Mu-type opioid receptorCavia porcellus (domestic guinea pig)1.6
Serine/threonine-protein kinase pim-3Homo sapiens (human)1.4
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)1.72
Serine/threonine-protein kinase PLK3Homo sapiens (human)3

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gainor, JP; Minnear, FL; Morton, CA; Roberts, JT; Vincent, PA1
Forough, R; Granger, HJ; Meininger, CJ; Steinle, JJ; Wu, G; Wu, MH1
Kanamori, A; Mukuno, H; Nagai, A; Nakamura, M; Negi, A; Seigel, G1
Chen, J; Du, X; Nanamori, M; Ye, RD1

Other Studies

4 other study(ies) available for kt 5823 and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
Platelet-conditioned medium increases endothelial electrical resistance independently of cAMP/PKA and cGMP/PKG.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:5

    Topics: Alkaloids; Androstadienes; Animals; Blood Platelets; Carbazoles; Cattle; Cells, Cultured; Chromones; Culture Media, Conditioned; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Electric Impedance; Endothelium, Vascular; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Indoles; Lysophospholipids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Pulmonary Artery; Wortmannin

2001
Eph B4 receptor signaling mediates endothelial cell migration and proliferation via the phosphatidylinositol 3-kinase pathway.
    The Journal of biological chemistry, 2002, Nov-15, Volume: 277, Issue:46

    Topics: Alkaloids; Azepines; Blotting, Western; Calcium; Carbazoles; Cell Division; Cell Movement; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Humans; Indoles; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microcirculation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neovascularization, Pathologic; Nitric Oxide; Nitrites; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Receptor, EphB4; Signal Transduction; Time Factors

2002
Unoprostone isopropyl rescues retinal progenitor cells from apoptosis in vitro.
    Current eye research, 2004, Volume: 29, Issue:6

    Topics: Animals; Apoptosis; Carbazoles; Caspase 3; Caspases; Chromones; Cyclic GMP-Dependent Protein Kinases; Cytoprotection; Dinoprost; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Indoles; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Retina; Stem Cells

2004
Regulation of leukocyte degranulation by cGMP-dependent protein kinase and phosphoinositide 3-kinase: potential roles in phosphorylation of target membrane SNARE complex proteins in rat mast cells.
    Journal of immunology (Baltimore, Md. : 1950), 2007, Jan-01, Volume: 178, Issue:1

    Topics: Animals; Carbazoles; Cell Degranulation; Cell Line, Tumor; Cell Membrane; Chromones; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Humans; Indoles; Leukocytes; Mast Cells; Membrane Proteins; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, IgE; SNARE Proteins; Thionucleotides

2007