Page last updated: 2024-09-02

kt 5823 and 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one

kt 5823 has been researched along with 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one in 38 studies

Compound Research Comparison

Studies
(kt 5823)
Trials
(kt 5823)
Recent Studies (post-2010)
(kt 5823)
Studies
(1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one)
Trials
(1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one)
Recent Studies (post-2010) (1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one)
3170597930110

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (13.16)18.2507
2000's24 (63.16)29.6817
2010's9 (23.68)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Loweth, AC; Morgan, NG; Scarpello, JH; Williams, GT1
Cohen, A; Fouty, B; Komalavilas, P; Lincoln, TM; McMurtry, IF; Muramatsu, M; Rodman, DM1
Anwyl, R; Rowan, MJ; Wang, Y; Wu, J1
Polte, T; Schröder, H1
Alonso-Galicia, M; Harder, DR; Hudetz, AG; Roman, RJ; Shen, H1
Johns, RA; Li, D; Shirakami, G; Zhan, X1
Karlsson, AM; Loitto, VM; Nilsson, HM; Sundqvist, T; Svensson, SP1
Ferreyra, GA; Golombek, DA1
Ho-Pao, CL; Leamey, CA; Sur, M1
Herring, N; Paterson, DJ1
Ahern, GP; Jackson, MB; Klyachko, VA1
Iida, H; Inoue, N; Ishida, H; Ishikawa, Y; Yuan, Z1
Chanaud, B; Chancerelle, Y; De Sousa, M; Dinh-Xuan, AT; Florentin, I; Giroud, JP; Levacher, M; Mathieu, J; Strzalko, S; Valenti, L1
Beckman, DL; Liu, L; Mehta, P; Sun, P; Wang, J1
Arai, RJ; Debbas, V; Monteiro, HP; Morais, MS; Oliveira, CJ; Schindler, F; Stern, A; Ventura, AM1
Bátkai, S; Begg, M; Kunos, G; Lovinger, DM; Mo, FM; Offertaler, L; Pacher, P; Razdan, RK1
Chan, SL; Fiscus, RR1
De Godoy, M; Li, F; Rattan, S1
Cunha, FQ; Ferreira, SH; Sachs, D1
Brading, AF; Deka, DK1
Bianciotti, LG; di Nunzio, A; Hope, SI; Legaz, G; Morgazo, C; Perfume, G; Vatta, MS1
Araiza-Saldaña, CI; Bermúdez-Ocaña, DY; Granados-Soto, V; Pérez-Severiano, F; Reyes-García, G1
Flores-Murrieta, FJ; Granados-Soto, V; Mixcoatl-Zecuatl, T1
Brito, GA; Cunha, FQ; Ferreira, SH; Lotufo, CM; Ribeiro, RA; Sachs, D; Vale, ML1
Ahmad, S; Ahmed, A; Ahmed, S; Al-Ani, B; Cudmore, M; Fujisawa, T; Hewett, PW1
Anand-Srivastava, MB; Bassil, M; Li, Y1
Ishikawa, T; Nakayama, K; Sunouchi, T; Suzuki, K1
Donat, U; Felix, SB; Frenzel, M; Krieg, T; Kroemer, HK; Maas, O; Rütz, T1
Anand-Srivastava, MB; Arejian, M; Li, Y1
Arendshorst, WJ; Fellner, SK1
Chen, SD; Hwang, CS; Tang, CM; Yang, DI1
Chen, XF; Huang, YJ; Lin, DY; Xu, XL; Zhang, W1
Carvalho, FB; Ferreira, J; Girardi, BA; Marisco, PC; Mello, CF; Oliveira, MS; Rubin, MA; Tonello, R1
Aponte, AM; Kohr, MJ; Murphy, E; Steenbergen, C; Sun, J; Tong, G1
Kosakai, K; Tsujiuchi, Y; Yoshino, M1
Lueptow, LM; O'Donnell, JM; Zhan, CG1
Artinian, L; Estes, S; Rehder, V1
Bae, H; Bang, H; Choi, J; Kim, JH; Kim, T; Kim, YW; Ko, JH; Lee, D; Lim, I1

Other Studies

38 other study(ies) available for kt 5823 and 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one

ArticleYear
Evidence for the involvement of cGMP and protein kinase G in nitric oxide-induced apoptosis in the pancreatic B-cell line, HIT-T15.
    FEBS letters, 1997, Jan-06, Volume: 400, Issue:3

    Topics: Alkaloids; Animals; Apoptosis; Carbazoles; Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Indoles; Islets of Langerhans; Nitroso Compounds; Oxadiazoles; Quinoxalines; S-Nitrosoglutathione

1997
Protein kinase G is not essential to NO-cGMP modulation of basal tone in rat pulmonary circulation.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Alkaloids; Animals; Blood Pressure; Carbazoles; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hypertension, Pulmonary; Indoles; Lung; Male; Nitric Oxide; Oxadiazoles; Protein Kinase Inhibitors; Protein Kinases; Pulmonary Circulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Thionucleotides; Vascular Resistance; Vasoconstriction

1998
Evidence for involvement of the cGMP-protein kinase G signaling system in the induction of long-term depression, but not long-term potentiation, in the dentate gyrus in vitro.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, May-15, Volume: 18, Issue:10

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Alkaloids; Animals; Benzoates; Carbazoles; Cyclic GMP; Dentate Gyrus; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; GTP-Binding Proteins; Guanylate Cyclase; Indoles; Long-Term Potentiation; Neurons; Oxadiazoles; Phosphodiesterase Inhibitors; Protein Kinases; Purinones; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Signal Transduction

1998
Cyclic AMP mediates endothelial protection by nitric oxide.
    Biochemical and biophysical research communications, 1998, Oct-20, Volume: 251, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Alkaloids; Animals; Carbazoles; Cattle; Cell Line; Cell Survival; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic N-Oxides; Dideoxyadenosine; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Indoles; Kinetics; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Pulmonary Artery; Pyrroles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha

1998
Contribution of 20-HETE to vasodilator actions of nitric oxide in the cerebral microcirculation.
    Stroke, 1999, Volume: 30, Issue:12

    Topics: Adenosine; Alkaloids; Amides; Animals; Basilar Artery; Carbazoles; Cerebrovascular Circulation; Cyclic GMP; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; Hydroxyeicosatetraenoic Acids; Indoles; Male; Microcirculation; Middle Cerebral Artery; Mixed Function Oxygenases; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Sulfones; Vasodilation; Vasodilator Agents

1999
Regulation of ciliary beat frequency by the nitric oxide-cyclic guanosine monophosphate signaling pathway in rat airway epithelial cells.
    American journal of respiratory cell and molecular biology, 2000, Volume: 23, Issue:2

    Topics: Alkaloids; Animals; Arginine; Carbazoles; Cells, Cultured; Cilia; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Glutathione; Indoles; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; omega-N-Methylarginine; Oxadiazoles; Purinones; Quinoxalines; Rats; S-Nitrosoglutathione; Signal Transduction; Trachea

2000
Nitric oxide modulates intracellular translocation of pigment organelles in Xenopus laevis melanophores.
    Cell motility and the cytoskeleton, 2000, Volume: 47, Issue:3

    Topics: Alkaloids; Animals; Arginine; Biological Transport; Blotting, Western; Carbazoles; Cells, Cultured; Cyclic GMP; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Guanylate Cyclase; Indoles; Melanophores; Microscopy, Fluorescence; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Signal Transduction; Time Factors; Xenopus laevis

2000
Rhythmicity of the cGMP-related signal transduction pathway in the mammalian circadian system.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Brain; Carbazoles; Circadian Rhythm; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Darkness; Enzyme Inhibitors; Indoles; Injections, Intraventricular; Isoenzymes; Light; Male; Mammals; Mesocricetus; Motor Activity; Oxadiazoles; Photoperiod; Quinoxalines; Signal Transduction; Suprachiasmatic Nucleus

2001
Disruption of retinogeniculate pattern formation by inhibition of soluble guanylyl cyclase.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jun-01, Volume: 21, Issue:11

    Topics: Aging; Alkaloids; Animals; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Ferrets; Geniculate Bodies; Guanylate Cyclase; In Vitro Techniques; Indoles; Neuropil; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Presynaptic Terminals; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Signal Transduction; Synaptophysin

2001
Nitric oxide-cGMP pathway facilitates acetylcholine release and bradycardia during vagal nerve stimulation in the guinea-pig in vitro.
    The Journal of physiology, 2001, Sep-01, Volume: 535, Issue:Pt 2

    Topics: Acetylcholine; Alkaloids; Animals; Bradycardia; Calcium Channel Blockers; Calcium Channels; Carbachol; Carbazoles; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Female; Guanylate Cyclase; Guinea Pigs; Heart Rate; In Vitro Techniques; Indoles; Isoquinolines; Milrinone; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; omega-Conotoxin GVIA; Oxadiazoles; Phosphorylation; Presynaptic Terminals; Quinoxalines; Sinoatrial Node; Sulfonamides; Synaptic Transmission; Tritium; Vagus Nerve

2001
cGMP-mediated facilitation in nerve terminals by enhancement of the spike afterhyperpolarization.
    Neuron, 2001, Sep-27, Volume: 31, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Alkaloids; Animals; Calcium; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Ion Channel Gating; Ion Transport; Ionomycin; Isoquinolines; Large-Conductance Calcium-Activated Potassium Channels; Nerve Tissue Proteins; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Oxadiazoles; Patch-Clamp Techniques; Photolysis; Pituitary Gland, Posterior; Potassium; Potassium Channels; Potassium Channels, Calcium-Activated; Quinoxalines; Signal Transduction; Sodium; Sodium Channels; Sulfonamides; Thionucleotides

2001
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
    European journal of pharmacology, 2003, Mar-19, Volume: 464, Issue:2-3

    Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases

2003
Nitric oxide inhibits spleen cell proliferative response after burn injury by inducing cytostasis, apoptosis, and necrosis of activated T lymphocytes: role of the guanylate cyclase.
    Cellular immunology, 2003, Volume: 221, Issue:1

    Topics: Alkaloids; Aminoquinolines; Animals; Apoptosis; Burns; Carbazoles; Cell Division; Cells, Cultured; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Lymphocyte Activation; Male; Necrosis; Nitric Oxide; Oxadiazoles; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Skin; Spleen; T-Lymphocytes

2003
Effect of nitric oxide on lung surfactant secretion.
    Experimental lung research, 2003, Volume: 29, Issue:5

    Topics: Animals; Carbazoles; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Guanidines; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Perfusion; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Quinoxalines; Rats; Rats, Sprague-Dawley; Spermine

2003
Nitric oxide and cGMP activate the Ras-MAP kinase pathway-stimulating protein tyrosine phosphorylation in rabbit aortic endothelial cells.
    Free radical biology & medicine, 2003, Aug-15, Volume: 35, Issue:4

    Topics: Animals; Aorta; Blotting, Western; Carbazoles; Cyclic GMP; Cytosol; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Free Radicals; Genes, Dominant; Glutathione Transferase; Indoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Nitric Oxide; Nitroprusside; Oxadiazoles; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins p21(ras); Quinoxalines; Rabbits; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Transfection; Tyrosine

2003
G protein-coupled endothelial receptor for atypical cannabinoid ligands modulates a Ca2+-dependent K+ current.
    The Journal of biological chemistry, 2003, Nov-14, Volume: 278, Issue:46

    Topics: Animals; Arteries; Calcium; Cannabinoids; Carbazoles; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Dronabinol; Electrophysiology; Endothelium; Endothelium, Vascular; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Humans; Indoles; Kinetics; Ligands; Male; Membrane Potentials; Oxadiazoles; Patch-Clamp Techniques; Peptides; Pertussis Toxin; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Resorcinols; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Umbilical Veins; Vasodilator Agents

2003
Guanylyl cyclase inhibitors NS2028 and ODQ and protein kinase G (PKG) inhibitor KT5823 trigger apoptotic DNA fragmentation in immortalized uterine epithelial cells: anti-apoptotic effects of basal cGMP/PKG.
    Molecular human reproduction, 2003, Volume: 9, Issue:12

    Topics: Animals; Apoptosis; Carbazoles; Cell Line, Transformed; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA; DNA Fragmentation; Enzyme Inhibitors; Epithelial Cells; Female; Guanylate Cyclase; Indoles; Oxadiazoles; Oxazines; Quinoxalines; Signal Transduction; Uterus

2003
Role of adenylate and guanylate cyclases in beta1-, beta2-, and beta3-adrenoceptor-mediated relaxation of internal anal sphincter smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:3

    Topics: Adenine; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blotting, Western; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanylate Cyclase; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Oxadiazoles; Procaterol; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; Suramin; Xamoterol

2004
Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Mar-09, Volume: 101, Issue:10

    Topics: Adenosine Triphosphate; Analgesics; Animals; Arginine; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Indoles; Male; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Signal Transduction

2004
Nitric oxide activates glibenclamide-sensitive K+ channels in urinary bladder myocytes through a c-GMP-dependent mechanism.
    European journal of pharmacology, 2004, May-10, Volume: 492, Issue:1

    Topics: Adenosine Triphosphate; Animals; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Glyburide; Guinea Pigs; Indoles; Ion Channel Gating; Male; Membrane Potentials; Molsidomine; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Patch-Clamp Techniques; Potassium Channels; Quinoxalines; Signal Transduction; Urinary Bladder

2004
Involvement of nitric oxide pathways in short term modulation of tyrosine hydroxylase activity by endothelins 1 and 3 in the rat anterior hypothalamus.
    Biochemical and biophysical research communications, 2005, Sep-02, Volume: 334, Issue:3

    Topics: Animals; Carbazoles; Cyclic GMP; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelin-3; Hypothalamus, Anterior; Indazoles; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroprusside; Oligopeptides; Oxadiazoles; Piperidines; Quinoxalines; Rats; Suramin; Tyrosine 3-Monooxygenase

2005
Effect of diabetes on the mechanisms of intrathecal antinociception of sildenafil in rats.
    European journal of pharmacology, 2005, Dec-19, Volume: 527, Issue:1-3

    Topics: Analgesia; Animals; Blood Glucose; Body Weight; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Guanylate Cyclase; Indoles; Injections, Spinal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Streptozocin; Sulfones; Time Factors

2005
The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Amines; Analgesics; Animals; Apamin; Carbazoles; Charybdotoxin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Diazoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Indazoles; Indoles; Injections, Spinal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Okadaic Acid; Oxadiazoles; Pain; Pinacidil; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Spinal Nerves; Stereoisomerism; Time Factors; Vasodilator Agents

2006
Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K channel pathway.
    The European journal of neuroscience, 2006, Volume: 24, Issue:4

    Topics: Adenosine Triphosphate; Analgesia; Analgesics; Animals; Arginine; Bucladesine; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Ganglia, Spinal; Glyburide; Indoles; KATP Channels; Male; Neurons; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Pain Measurement; Pertussis Toxin; Potassium Channels, Inwardly Rectifying; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Tolbutamide

2006
The release of nitric oxide from S-nitrosothiols promotes angiogenesis.
    PloS one, 2006, Dec-20, Volume: 1

    Topics: Animals; Ascorbic Acid; Carbazoles; Cells, Cultured; Culture Media, Serum-Free; Cyclic GMP-Dependent Protein Kinases; Dithiothreitol; Endothelial Cells; Enzyme Inhibitors; Guanylate Cyclase; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroarginine; Ornithine; Oxadiazoles; Phosphorylation; Quinoxalines; S-Nitrosothiols; Swine

2006
Peroxynitrite inhibits the expression of G(i)alpha protein and adenylyl cyclase signaling in vascular smooth muscle cells.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Animals; Aorta, Thoracic; Blotting, Western; Carbazoles; Cells, Cultured; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Indoles; Mitogen-Activated Protein Kinases; Muscle Relaxation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxadiazoles; Peroxynitrous Acid; Quinoxalines; Rats; Receptor, Angiotensin, Type 1; Receptors, Atrial Natriuretic Factor; Signal Transduction

2008
Dual effect of nitric oxide on ATP-sensitive K+ channels in rat pancreatic beta cells.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 456, Issue:3

    Topics: Adenosine Triphosphate; Animals; Carbazoles; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Diazoxide; Dose-Response Relationship, Drug; Guanylate Cyclase; Insulin; Insulin-Secreting Cells; KATP Channels; Male; Membrane Potentials; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Patch-Clamp Techniques; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Triazenes; Uncoupling Agents

2008
Vardenafil protects isolated rat hearts at reperfusion dependent on GC and PKG.
    British journal of pharmacology, 2008, Volume: 154, Issue:1

    Topics: Animals; Calcium; Carbazoles; Cell Adhesion Molecules; Cell Death; Cell Line; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Microfilament Proteins; Mitochondria, Heart; Mitochondrial Membranes; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoproteins; Piperazines; Quinoxalines; Rats; Sulfones; Triazines; Vardenafil Dihydrochloride

2008
Nitric oxide attenuates the expression of natriuretic peptide receptor C and associated adenylyl cyclase signaling in aortic vascular smooth muscle cells: role of MAPK.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Aorta; Carbazoles; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; GTP-Binding Protein alpha Subunits, Gi-Go; MAP Kinase Signaling System; Metalloporphyrins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Phosphorylation; Protein Kinase Inhibitors; Quinoxalines; Rats; Receptors, Atrial Natriuretic Factor; S-Nitroso-N-Acetylpenicillamine

2009
Complex interactions of NO/cGMP/PKG systems on Ca2+ signaling in afferent arteriolar vascular smooth muscle.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; ADP-ribosyl Cyclase; Animals; Arterioles; Calcium; Calcium Signaling; Carbazoles; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activators; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Peptides; Phosphodiesterase Inhibitors; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley

2010
Neuroprotective mechanisms of minocycline against sphingomyelinase/ceramide toxicity: Roles of Bcl-2 and thioredoxin.
    Free radical biology & medicine, 2011, Mar-15, Volume: 50, Issue:6

    Topics: Animals; Blotting, Western; Carbazoles; Cells, Cultured; Ceramides; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Dinitrochlorobenzene; Genes, bcl-2; Minocycline; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Proto-Oncogene Proteins c-bcl-2; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sphingomyelin Phosphodiesterase; Thioredoxins

2011
2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation of vascular smooth muscle cells: involvement of NO/cGMP/PKG pathway.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:7

    Topics: Animals; Becaplermin; Carbazoles; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Glucosides; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Polygonum; Proto-Oncogene Proteins c-sis; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes

2012
Spermidine decreases Na⁺,K⁺-ATPase activity through NMDA receptor and protein kinase G activation in the hippocampus of rats.
    European journal of pharmacology, 2012, Jun-05, Volume: 684, Issue:1-3

    Topics: Animals; Biguanides; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dizocilpine Maleate; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Spermidine

2012
Essential role of nitric oxide in acute ischemic preconditioning: S-nitros(yl)ation versus sGC/cGMP/PKG signaling?
    Free radical biology & medicine, 2013, Volume: 54

    Topics: Animals; Ascorbic Acid; Carbazoles; Cells, Cultured; Cyclic GMP-Dependent Protein Kinases; Guanylate Cyclase; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Inbred C57BL; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrosation; Organ Culture Techniques; Oxadiazoles; Quinoxalines; Reperfusion Injury; Signal Transduction

2013
Nitric oxide augments single Ca(2+) channel currents via cGMP-dependent protein kinase in Kenyon cells isolated from the mushroom body of the cricket brain.
    Journal of insect physiology, 2015, Volume: 78

    Topics: Action Potentials; Animals; Brain; Calcium Channels; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Gryllidae; Male; Mushroom Bodies; Neurons; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Quinoxalines; S-Nitrosoglutathione; Signal Transduction

2015
Cyclic GMP-mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice.
    Psychopharmacology, 2016, Volume: 233, Issue:3

    Topics: Animals; Carbazoles; Cell Adhesion Molecules; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 2; Dose-Response Relationship, Drug; Guanylate Cyclase; Imidazoles; Male; Memory; Mice, Inbred ICR; Microfilament Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoproteins; Protein Kinase Inhibitors; Quinoxalines; Recognition, Psychology; Triazines

2016
Modulation of growth cone filopodial length by carbon monoxide.
    Developmental neurobiology, 2017, Volume: 77, Issue:6

    Topics: Action Potentials; Animals; Calcium; Carbazoles; Carbon Monoxide; Enzyme Inhibitors; Ganglia, Invertebrate; Growth Cones; Heme Oxygenase-1; Neurons; Nitric Oxide; Organometallic Compounds; Oxadiazoles; Oxazines; Patch-Clamp Techniques; Pseudopodia; Quinoxalines; Signal Transduction; Snails; Time Factors

2017
Effects of Nitric Oxide on Voltage-Gated K⁺ Currents in Human Cardiac Fibroblasts through the Protein Kinase G and Protein Kinase A Pathways but Not through S-Nitrosylation.
    International journal of molecular sciences, 2018, Mar-12, Volume: 19, Issue:3

    Topics: Action Potentials; Adenine; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Myofibroblasts; Nitric Oxide; Oxadiazoles; Potassium Channels, Voltage-Gated; Pyrroles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine

2018