krn-7000 and titanium-tetrachloride

krn-7000 has been researched along with titanium-tetrachloride* in 1 studies

Other Studies

1 other study(ies) available for krn-7000 and titanium-tetrachloride

Article	Year
Lewis Acid Induced Anomerization of Se-Glycosides. Application to Synthesis of α-Se-GalCer. Organic letters, 2016, Feb-05, Volume: 18, Issue:3 The TiCl4 induced anomerization of selenium glycosides of galacturonic acid derivatives is reported. The reaction was successful for galacturonic acid when various alkyl, alkenyl, alkynyl, saccharide, steroid, and lipid groups were attached to the anomeric Se atom. An increased amount of TiCl4 and/or higher temperature were needed to ensure completion of the reaction in some cases. Yields were higher for reactions carried out at higher dilution. The reaction was applied to the synthesis of Se-based mimics of the potent immunostimulant α-GalCer (KRN7000). Topics: Adjuvants, Immunologic; Galactosylceramides; Glycosides; Lewis Acids; Molecular Structure; Organoselenium Compounds; Selenium; Titanium	2016

Article

Year

Lewis Acid Induced Anomerization of Se-Glycosides. Application to Synthesis of α-Se-GalCer.

Organic letters, 2016, Feb-05, Volume: 18, Issue:3

The TiCl4 induced anomerization of selenium glycosides of galacturonic acid derivatives is reported. The reaction was successful for galacturonic acid when various alkyl, alkenyl, alkynyl, saccharide, steroid, and lipid groups were attached to the anomeric Se atom. An increased amount of TiCl4 and/or higher temperature were needed to ensure completion of the reaction in some cases. Yields were higher for reactions carried out at higher dilution. The reaction was applied to the synthesis of Se-based mimics of the potent immunostimulant α-GalCer (KRN7000).

Topics: Adjuvants, Immunologic; Galactosylceramides; Glycosides; Lewis Acids; Molecular Structure; Organoselenium Compounds; Selenium; Titanium

2016