kojic acid and hydroquinone

kojic acid has been researched along with hydroquinone in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.63)	18.7374
1990's	5 (13.16)	18.2507
2000's	15 (39.47)	29.6817
2010's	14 (36.84)	24.3611
2020's	3 (7.89)	2.80

Authors

Authors	Studies
Li, CY; Wu, TS	1
Lee, EJ; Li, CY; Wu, TS	1
Bae, S; Chung, HY; Ha, YM; Jin, Y; Lee, H; Song, S; Suh, H	1
Criton, M; Le Mellay-Hamon, V	1
Bae, K; Chen, QC; Min, BS; Youn, U	1
Bae, K; Ha, do T; Kim, H; Lee, I; Min, B; Ngoc, TM	1
Curtis-Long, MJ; Jang, KC; Lee, CW; Park, KH; Ryu, HW; Ryu, YB; Seo, WD	1
Choi, S; Choi, SY; Ha, SK; Hwang, S; In, J; Kim, S; Kim, SY; Kim, TY; Lee, E; Lee, JH	1
Bae, SJ; Choi, J; Chung, HY; Ha, YM; Lee, EK; Lee, H; Lee, JS; No, JK; Song, S; Suh, H; Yu, BP	1
Carpinella, MC; Chiari, ME; Palacios, SM; Vera, DM	1
Ahn, SM; Cho, JC; Joo, YH; Kim, JE; Lee, CS; Lee, J; Park, SN; Park, YH; Rho, HS; Shin, SS; Suh, KD	1
Bengeloune, AH; Bertin, D; De Pomyers, H; Gigmes, D; Luis, J; Mabrouk, K; Roudaut, H; Verdoni, M	1
Davis, R; Ilic-Tomic, T; Nikodinovic-Runic, J; O'Connor, K; Pavic, A; Veselinović, AM; Veselinović, JB	1
Jung, SH; Manickam, M; Namasivayam, V; Pillaiyar, T	1
Haudecoeur, R; Pérès, B; Roulier, B	1
Cui, X; Deng, Y; Fu, D; Li, G; Qin, F; Tang, Z; Xu, Y; Yao, S; Yuan, Y	1
Nair, X; Tramposch, KM	1
Rubin, MG	1
Fulton, JE; Garcia, A	1
Hearing, VJ; Kobayashi, N; Matsunaga, J; Virador, VM	1
Lim, JT	1
Duval, C; Galey, JB; Lagrange, A; Philippe, M; Régnier, M; Schmidt, R; Tuloup, R	1
Hearing, VJ; Lei, TC; Vieira, WD; Virador, VM	1
Ahn, KS; Kim, YS; Lee, J; Moon, KY	1
Halder, RM; Richards, GM	1
Gover, MD; Gupta, AK; Nouri, K; Taylor, S	1
Lin, YH; Wu, SM; Yang, YH	1
Buggiani, G; Lotti, T; Ortonne, JP; Prignano, F	1
Chung, HY; Chung, SW; Ha, YM; Lee, H; Song, S; Suh, H	1
Ishii, F; Ishikawa, M; Kawase, I	1
Afifi, FU; Amro, BI; Issa, RA	1
Bhushan, P; Draelos, ZD; Oresajo, C; Pillai, S; Yatskayer, M	1
Ahlheit, S; Batzer, J; Gerwat, W; Kolbe, L; Mann, T; Scherner, C; Stäb, F; Wenck, H	1
Gruber, JV; Holtz, R	1
Davids, LM; Jardine, A; Khumalo, NP; Maneli, MH; Smith, P; Spengane, Z; Tinguely, C; van Wyk, JC; Wiesner, L	1
Shokeen, D	1
Adir, N; Deri, B; Fishman, A; Goldfeder, M; Guallar, V; Kanteev, M; Lecina, D	1
Nautiyal, A; Wairkar, S	1

Reviews

6 review(s) available for kojic acid and hydroquinone

Article	Year
Inhibitors of Melanogenesis: An Updated Review. Journal of medicinal chemistry, 2018, 09-13, Volume: 61, Issue:17 Topics: alpha-MSH; Biphenyl Compounds; Crystallization; Enzyme Inhibitors; Humans; Melanins; Monophenol Monooxygenase; Peptidomimetics; Radiation, Ionizing; Resveratrol; Signal Transduction; Skin	2018
Advances in the Design of Genuine Human Tyrosinase Inhibitors for Targeting Melanogenesis and Related Pigmentations. Journal of medicinal chemistry, 2020, 11-25, Volume: 63, Issue:22 Topics: Agaricales; Amino Acid Sequence; Biological Factors; Drug Delivery Systems; Drug Design; Enzyme Inhibitors; Humans; Melanins; Melanocytes; Melanoma; Monophenol Monooxygenase; Pigmentation; Protein Structure, Secondary; Skin Lightening Preparations	2020
Management of dyschromias in ethnic skin. Dermatologic therapy, 2004, Volume: 17, Issue:2 Topics: Administration, Cutaneous; Arbutin; Black People; Dicarboxylic Acids; Humans; Hydroquinones; Keratolytic Agents; Pigmentation Disorders; Pyrones; Tretinoin	2004
The treatment of melasma: a review of clinical trials. Journal of the American Academy of Dermatology, 2006, Volume: 55, Issue:6 Topics: Adrenal Cortex Hormones; Adult; Chemexfoliation; Clinical Trials as Topic; Combined Modality Therapy; Dermabrasion; Dicarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Flavonoids; Gonadal Steroid Hormones; Humans; Hydroquinones; Laser Coagulation; Melanosis; Phototherapy; Plant Extracts; Pregnancy; Pregnancy Complications; Pyrones; Randomized Controlled Trials as Topic; Skin; Sunlight; Treatment Outcome; Tretinoin; Ultraviolet Rays	2006
Postinflammatory hyperpigmentation in patients with skin of color. Cutis, 2016, Volume: 97, Issue:1 Topics: Chemexfoliation; Dermatitis; Dermatologic Agents; Dicarboxylic Acids; Drug Combinations; Ethanol; Glycolates; Humans; Hydroquinones; Hyperpigmentation; Inflammation; Keratolytic Agents; Lactic Acid; Pyrones; Resorcinols; Salicylates; Salicylic Acid; Skin Pigmentation; Tretinoin	2016
Management of hyperpigmentation: Current treatments and emerging therapies. Pigment cell & melanoma research, 2021, Volume: 34, Issue:6 Topics: Glycolates; Humans; Hydroquinones; Hyperpigmentation; Pyrones; Skin	2021

Trials

3 trial(s) available for kojic acid and hydroquinone

Article	Year
Treatment of melasma using kojic acid in a gel containing hydroquinone and glycolic acid. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1999, Volume: 25, Issue:4 Topics: Adult; Aspergillus oryzae; Double-Blind Method; Drug Combinations; Facial Dermatoses; Female; Gels; Glycolates; Humans; Hydroquinones; Keratolytic Agents; Melanosis; Middle Aged; Mycotoxins; Pyrones; Treatment Outcome	1999
Evaluation of a kojic acid, emblica extract, and glycolic acid formulation compared with hydroquinone 4% for skin lightening. Cutis, 2010, Volume: 86, Issue:3 Topics: Administration, Cutaneous; Adult; Antioxidants; Dermatologic Agents; Double-Blind Method; Drug Combinations; Face; Female; Follow-Up Studies; Glycolates; Humans; Hydroquinones; Keratolytic Agents; Middle Aged; Phyllanthus emblica; Pigmentation Disorders; Plant Extracts; Pyrones; Treatment Outcome	2010
4-n-butylresorcinol, a highly effective tyrosinase inhibitor for the topical treatment of hyperpigmentation. Journal of the European Academy of Dermatology and Venereology : JEADV, 2013, Volume: 27 Suppl 1 Topics: Administration, Topical; Aged; Arbutin; Female; Humans; Hydroquinones; Hyperpigmentation; Melanins; Middle Aged; Monophenol Monooxygenase; Pyrones; Resorcinols; Single-Blind Method; Skin; Skin Lightening Preparations; Tissue Culture Techniques; Treatment Outcome	2013

Other Studies

29 other study(ies) available for kojic acid and hydroquinone

Article	Year
Constituents of the stigmas of Crocus sativus and their tyrosinase inhibitory activity. Journal of natural products, 2002, Volume: 65, Issue:10 Topics: Crocus; Enzyme Inhibitors; Monophenol Monooxygenase; Spectrum Analysis	2002
Antityrosinase principles and constituents of the petals of Crocus sativus. Journal of natural products, 2004, Volume: 67, Issue:3 Topics: China; Crocus; Enzyme Inhibitors; Flowers; Free Radical Scavengers; Hydroxybutyrates; Kaempferols; Molecular Structure; Monophenol Monooxygenase; Monoterpenes; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal	2004
Syntheses of hydroxy substituted 2-phenyl-naphthalenes as inhibitors of tyrosinase. Bioorganic & medicinal chemistry letters, 2007, Jan-15, Volume: 17, Issue:2 Topics: Agaricales; Crystallography, X-Ray; Dealkylation; Enzyme Inhibitors; Hydroquinones; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Monophenol Monooxygenase; Morus; Naphthalenes; Pyrones; Resveratrol; Stilbenes	2007
Analogues of N-hydroxy-N'-phenylthiourea and N-hydroxy-N'-phenylurea as inhibitors of tyrosinase and melanin formation. Bioorganic & medicinal chemistry letters, 2008, Jun-15, Volume: 18, Issue:12 Topics: Agaricales; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Melanins; Melanocytes; Melanoma; Mice; Molecular Structure; Monophenol Monooxygenase; Peptides; Phenylthiourea; Stereoisomerism; Structure-Activity Relationship; Toxicity Tests	2008
Pyronane monoterpenoids from the fruit of Gardenia jasminoides. Journal of natural products, 2008, Volume: 71, Issue:6 Topics: Agaricales; Circular Dichroism; Dose-Response Relationship, Drug; Fruit; Gardenia; Korea; Levodopa; Molecular Structure; Monophenol Monooxygenase; Monoterpenes; Plants, Medicinal	2008
Tyrosinase-inhibitory constituents from the twigs of Cinnamomum cassia. Journal of natural products, 2009, Volume: 72, Issue:6 Topics: Cinnamomum aromaticum; Glycosides; Inhibitory Concentration 50; Korea; Monophenol Monooxygenase; Nuclear Magnetic Resonance, Biomolecular; Phenols; Plant Stems; Plants, Medicinal	2009
Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone. European journal of medicinal chemistry, 2010, Volume: 45, Issue:5 Topics: alpha-Glucosidases; Chalcone; Drug Design; Enzyme Activation; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Molecular Structure; Monophenol Monooxygenase; Pigments, Biological; Stereoisomerism; Structure-Activity Relationship; Sulfonamides	2010
Identification of a potent and noncytotoxic inhibitor of melanin production. Bioorganic & medicinal chemistry, 2010, Aug-01, Volume: 18, Issue:15 Topics: Amides; Animals; Benzamides; Cell Line; Combinatorial Chemistry Techniques; Guinea Pigs; Melanins; Melanocytes; Mice; Phenylthiourea; Skin; Structure-Activity Relationship; Ultraviolet Rays	2010
A newly synthesized, potent tyrosinase inhibitor: 5-(6-hydroxy-2-naphthyl)-1,2,3-benzenetriol. Bioorganic & medicinal chemistry letters, 2010, Aug-15, Volume: 20, Issue:16 Topics: Agaricales; Animals; Enzyme Inhibitors; Kinetics; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Naphthols; Pyrogallol; Pyrones; Resveratrol; Stilbenes	2010
Tyrosinase inhibitory activity of a 6-isoprenoid-substituted flavanone isolated from Dalea elegans. Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11 Topics: Agaricales; Binding Sites; Computer Simulation; Enzyme Inhibitors; Fabaceae; Flavanones; Kinetics; Monophenol Monooxygenase; Terpenes	2011
Depigmenting activities of kojic acid derivatives without tyrosinase inhibitory activities. Bioorganic & medicinal chemistry letters, 2012, Jun-15, Volume: 22, Issue:12 Topics: Adamantane; Agaricales; Animals; Biological Assay; Cell Survival; Esters; Melanins; Melanocytes; Mice; Monophenol Monooxygenase; Pigmentation; Pyrones; Structure-Activity Relationship; Tyrosine	2012
ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors. Bioorganic & medicinal chemistry, 2016, 11-15, Volume: 24, Issue:22 Topics: Animals; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Indoleacetic Acids; Melanins; Mice; Molecular Structure; Polyamines; Spider Venoms; Structure-Activity Relationship	2016
Potent anti-melanogenic activity and favorable toxicity profile of selected 4-phenyl hydroxycoumarins in the zebrafish model and the computational molecular modeling studies. Bioorganic & medicinal chemistry, 2017, 12-15, Volume: 25, Issue:24 Topics: Animals; Coumarins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Melanocytes; Models, Animal; Models, Molecular; Molecular Structure; Monophenol Monooxygenase; Structure-Activity Relationship; Zebrafish	2017
Design, synthesis and biological evaluation of tyrosinase-targeting PROTACs. European journal of medicinal chemistry, 2021, Dec-15, Volume: 226 Topics: Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Molecular Structure; Monophenol Monooxygenase; Proteolysis; Pyrones; Structure-Activity Relationship	2021
UVB-induced pigmentation in hairless mice as an in vivo assay for topical skin-depigmenting activity. Skin pharmacology : the official journal of the Skin Pharmacology Society, 1989, Volume: 2, Issue:4 Topics: Animals; Anisoles; Female; Hydroquinones; Mice; Mice, Hairless; Pyrones; Skin; Skin Pigmentation; Tretinoin; Ultraviolet Rays	1989
Chemical peeling as adjuvant therapy for facial neurotic excoriations. Journal of the American Academy of Dermatology, 1995, Volume: 32, Issue:2 Pt 1 Topics: Chemexfoliation; Facial Dermatoses; Glycolates; Humans; Hydroquinones; Hydroxy Acids; Neurotic Disorders; Pyrones; Self Mutilation; Self-Injurious Behavior	1995
The combination of glycolic acid and hydroquinone or kojic acid for the treatment of melasma and related conditions. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1996, Volume: 22, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Drug Evaluation; Drug Therapy, Combination; Female; Glycolates; Humans; Hydroquinones; Male; Melanosis; Middle Aged; Pregnancy; Pregnancy Complications; Pyrones; Radiation-Protective Agents; Time Factors	1996
A standardized protocol for assessing regulators of pigmentation. Analytical biochemistry, 1999, Jun-01, Volume: 270, Issue:2 Topics: Animals; Arbutin; Cell Division; Cell Line; Cell Survival; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Inhibitors; Hydroquinones; Melanins; Melanocyte-Stimulating Hormones; Melanocytes; Mice; Monophenol Monooxygenase; Niacinamide; Pyrimidine Dimers; Pyrones; Skin Pigmentation	1999
Keratinocyte-melanocyte co-cultures and pigmented reconstructed human epidermis: models to study modulation of melanogenesis. Cellular and molecular biology (Noisy-le-Grand, France), 1999, Volume: 45, Issue:7 Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Arbutin; Asian People; Benzofurans; Black People; Cells, Cultured; Coculture Techniques; Culture Media; Epidermal Cells; Ethnicity; Humans; Hydroquinones; Hydroxybenzoates; Indoles; Keratinocytes; Melanins; Melanocytes; Mice; Phenotype; Pyrones; Skin Pigmentation; Skin, Artificial; Theophylline; Thiophenes; Ultraviolet Rays; White People	1999
A melanocyte-keratinocyte coculture model to assess regulators of pigmentation in vitro. Analytical biochemistry, 2002, Jun-15, Volume: 305, Issue:2 Topics: Animals; Arbutin; Coculture Techniques; Dihydroxyphenylalanine; Hydroquinones; Keratinocytes; Melanocyte-Stimulating Hormones; Melanocytes; Mice; Models, Biological; Monophenol Monooxygenase; Niacinamide; Pigmentation; Pyrones	2002
Downregulation of NF-kappaB activation in human keratinocytes by melanogenic inhibitors. Journal of dermatological science, 2003, Volume: 31, Issue:3 Topics: Arbutin; Cell Line; Glycolates; Humans; Hydroquinones; Keratinocytes; NF-kappa B; Niacinamide; Pyrones; Recombinant Proteins; Resorcinols; Transfection; Ultraviolet Rays	2003
Experimental design and capillary electrophoresis for simultaneous analysis of arbutin, kojic acid and hydroquinone in cosmetics. Journal of pharmaceutical and biomedical analysis, 2007, May-09, Volume: 44, Issue:1 Topics: Arbutin; Buffers; Cosmetics; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Hydroquinones; Phosphates; Pyrones; Reference Standards; Regression Analysis; Reproducibility of Results; Research Design; Urea; Water	2007
Therapeutical approaches in melasma. Dermatologic clinics, 2007, Volume: 25, Issue:3 Topics: Chemexfoliation; Cosmetics; Dermatologic Agents; Dicarboxylic Acids; Drug Combinations; Humans; Hydroquinones; Hydroxybenzoates; Laser Therapy; Melanosis; Pyrones; Tretinoin	2007
4-(6-Hydroxy-2-naphthyl)-1,3-bezendiol: a potent, new tyrosinase inhibitor. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:9 Topics: Agaricales; Animals; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroquinones; Kinetics; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Naphthalenes; Naphthols; Phenols; Pyrones; Resorcinols; Resveratrol; Stilbenes	2007
Glycine inhibits melanogenesis in vitro and causes hypopigmentation in vivo. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:11 Topics: alpha-MSH; Amino Acids; Animals; Antioxidants; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Glycine; Hair Follicle; Hydroquinones; In Vitro Techniques; Melanins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Monophenol Monooxygenase; Pigmentation; Pyrones; Time Factors	2007
Studying the anti-tyrosinase effect of Arbutus andrachne L. extracts. International journal of cosmetic science, 2008, Volume: 30, Issue:4 Topics: Arbutin; Ericaceae; Hydroquinones; Inhibitory Concentration 50; Peptides; Plant Extracts; Plant Stems; Pyrones; Tyrosine	2008
Examining the impact of skin lighteners in vitro. Oxidative medicine and cellular longevity, 2013, Volume: 2013 Topics: Biological Assay; Cell Survival; Electron Transport Complex IV; Ferritins; Gene Expression Regulation; Humans; Hydroquinones; Keratinocytes; Melanins; Niacinamide; Pyrones; Receptor, Melanocortin, Type 1; Skin Lightening Preparations	2013
Combinations of potent topical steroids, mercury and hydroquinone are common in internationally manufactured skin-lightening products: a spectroscopic study. Clinical and experimental dermatology, 2016, Volume: 41, Issue:2 Topics: Betamethasone; Chromatography, High Pressure Liquid; Clobetasol; Hydroquinones; Mass Spectrometry; Mercury; Pyrones; Skin Lightening Preparations; South Africa; Spectrophotometry, Ultraviolet; Steroids	2016
The unravelling of the complex pattern of tyrosinase inhibition. Scientific reports, 2016, 10-11, Volume: 6 Topics: Bacillus megaterium; Enzyme Inhibitors; Hydroquinones; Hyperpigmentation; Kinetics; Melanins; Monophenol Monooxygenase; Pyrones; Skin	2016