knipholone has been researched along with chrysophanic-acid* in 2 studies
2 other study(ies) available for knipholone and chrysophanic-acid
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Phenylanthraquinones and flavone-C-glucosides from the disjunct Bulbinella in New Zealand.
The genera Bulbine, Bulbinella and Kniphofia produce phenylanthraquinones and are mostly found in southern Africa, although a disjunct group of Bulbinella species endemic to New Zealand also contain phenylanthraquinones as reported herein. The sub-Antarctic megaherb B. rossii yielded sulphated phenylanthraquinones, including a phenylanthraquinone found to carry a sulphated glycoside substituent, 4'-O-demethylknipholone-4'-β-D-xylopyranosyl-3″-sulphate. A sensitive HPLC method was used to analyse 5 of the 6 New Zealand Bulbinella species, all of which contained phenylanthraquinones. Leaves and roots had different profiles, but species were not distinct. Roots were rich in sulphated and free phenylanthraquinones (0.27 ± 0.09% dry wt), whereas leaves typically only contained free knipholone (0.14 ± 0.01%). Localisation of phenylanthraquinones to the stele and peel was observed in roots. Two flavone-C-glucosides were found in leaves of Bulbinella. Topics: Africa, Southern; Anthraquinones; Antimalarials; Chromatography, High Pressure Liquid; Flavones; Glucosides; Glycosides; Liliaceae; Magnoliopsida; Molecular Structure; New Zealand; Plant Leaves; Plant Roots | 2017 |
Secondary metabolites from Basotho medicinal plants. I. Bulbine narcissifolia.
The medicinal plant Bulbine narcissifolia is used by the Basotho, Griqua, and whites of southern Africa for wound healing and as a mild purgative. Extraction of the powdered root has yielded acetosyringone, chrysophanol, knipholone, isoknipholone, 10,7'-bichrysophanol, and chrysalodin in addition to two new anthraquinone glycosides, knipholone-8-O-beta-D-gentiobioside (1) and chrysalodin-10-beta-D-gentiobioside (2). NMR spectroscopy was used to elucidate the structures of 1 and 2 and to show that 1 binds weakly to DNA. Topics: Acetophenones; Anthraquinones; Chromatography, High Pressure Liquid; Circular Dichroism; Disaccharides; DNA; Lesotho; Liliaceae; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Plant Roots; Plants, Medicinal; South Africa; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Stereoisomerism; Structure-Activity Relationship; Wound Healing | 2001 |