kifunensine has been researched along with swainsonine in 13 studies
| Studies (kifunensine) | Trials (kifunensine) | Recent Studies (post-2010) (kifunensine) | Studies (swainsonine) | Trials (swainsonine) | Recent Studies (post-2010) (swainsonine) |
|---|---|---|---|---|---|
| 94 | 0 | 47 | 614 | 7 | 138 |
| Protein | Taxonomy | kifunensine (IC50) | swainsonine (IC50) |
|---|---|---|---|
| Chain A, Alpha-mannosidase Ii | Drosophila melanogaster (fruit fly) | 0.02 | |
| Chain A, ALPHA-MANNOSIDASE II | Drosophila melanogaster (fruit fly) | 0.02 | |
| Chain A, Alpha-mannosidase Ii | Drosophila melanogaster (fruit fly) | 0.02 | |
| Lysosomal alpha-mannosidase | Homo sapiens (human) | 0.03 | |
| Alpha-mannosidase 2C1 | Rattus norvegicus (Norway rat) | 1.75 | |
| Mannosyl-oligosaccharide alpha-1,2-mannosidase IA | Drosophila melanogaster (fruit fly) | 0.005 | |
| alpha-1,2-Mannosidase | Glycine max (soybean) | 0.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Chavan, S; Davies, GJ; Dinev, Z; Dumon, C; Gilbert, HJ; Moremen, KW; Siriwardena, A; Smith, N; Suits, MD; Thompson, AJ; Williams, SJ; Xiang, Y; Zhu, Y | 1 |
| Bischoff, J; Folkman, J; Nguyen, M | 1 |
| Elbein, AD | 1 |
| Ahrens, PB | 1 |
| Spiro, RG; Weng, S | 1 |
| Elbein, AD; Jackson, R; Pan, YT; Rice, K; Smith, S; Xu, B | 1 |
| Aricescu, AR; Chang, VT; Crispin, M; Davis, SJ; Dwek, RA; Harvey, DJ; Jones, EY; Rudd, PM; Yu, C | 1 |
| Funakoshi, Y; Hara, I; Kondo, A; Nakagawa, T; Nakano, M; Shigeta, M; Suzuki, T; Taniguchi, N | 1 |
| Aricescu, AR; Boles, KS; Chang, VT; Crispin, M; Davis, SJ; Dwek, RA; Evans, EJ; Fennelly, JA; Harvey, DJ; Jones, EY; Nettleship, JE; Owens, RJ; Stuart, DI; Yu, C | 1 |
| Mikell, I; Stamatatos, L | 1 |
| Copits, BA; Guzmán, YF; Stolz, JR; Swanson, GT; Vernon, CG | 1 |
| Choi, HY; Do, J; Hong, JK; Kim, DI; Kim, HH; Kim, SD; Kwon, JY; Lee, DY; Park, H; You, S | 1 |
| Fujiwara, H; Funamoto, S; Futai, E; Higashiura, R; Imai, S; Noguchi, N; Okuda, M; Sugimoto, H; Takahachi, M; Urano, Y | 1 |
1 review(s) available for kifunensine and swainsonine
| Article | Year |
|---|---|
Glycosidase inhibitors: inhibitors of N-linked oligosaccharide processing.
Topics: Alkaloids; Carbohydrate Sequence; Cyclopentanes; Drug Design; Glucosidases; Glycoside Hydrolases; Indolizines; Mannosidases; Molecular Sequence Data; Oligosaccharides; Protein Processing, Post-Translational; Swainsonine | 1991 |
12 other study(ies) available for kifunensine and swainsonine
| Article | Year |
|---|---|
Mechanistic insights into a Ca2+-dependent family of alpha-mannosidases in a human gut symbiont.
Topics: alpha-Mannosidase; Bacteroides; Calcium; Catalytic Domain; Crystallography, X-Ray; Humans; Intestines; Models, Molecular; Polysaccharides; Protein Structure, Tertiary; Substrate Specificity; Symbiosis | 2010 |
1-Deoxymannojirimycin inhibits capillary tube formation in vitro. Analysis of N-linked oligosaccharides in bovine capillary endothelial cells.
Topics: 1-Deoxynojirimycin; Adrenal Cortex; Alkaloids; Animals; Capillaries; Carbohydrate Conformation; Carbohydrate Sequence; Cattle; Cells, Cultured; Chromatography, Affinity; Chromatography, Gel; Clone Cells; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Glycopeptides; Mannose; Mannosidases; Molecular Sequence Data; Oligosaccharides; Swainsonine | 1992 |
Role of target cell glycoproteins in sensitivity to natural killer cell lysis.
Topics: 1-Deoxynojirimycin; Alkaloids; Antibodies, Monoclonal; Carbohydrate Conformation; Carbohydrate Sequence; Cell Adhesion Molecules; Concanavalin A; Cytotoxicity, Immunologic; Glycoproteins; Glycoside Hydrolases; Golgi Apparatus; Humans; Indolizines; Intercellular Adhesion Molecule-1; Killer Cells, Natural; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphocyte Function-Associated Antigen-1; Mannosidases; Molecular Sequence Data; Oligosaccharides; Swainsonine; Tumor Cells, Cultured | 1993 |
Endoplasmic reticulum kifunensine-resistant alpha-mannosidase is enzymatically and immunologically related to the cytosolic alpha-mannosidase.
Topics: Acetylglucosamine; Alkaloids; alpha-Mannosidase; Amino Acid Sequence; Animals; Cobalt; Cytosol; Drug Resistance; Endoplasmic Reticulum, Rough; Enzyme Inhibitors; Male; Mannose; Mannosidases; Molecular Sequence Data; Rats; Swainsonine | 1996 |
Specificity of the high-mannose recognition site between Enterobacter cloacae pili adhesin and HT-29 cell membranes.
Topics: 1-Deoxynojirimycin; Adhesins, Bacterial; Adhesins, Escherichia coli; Alkaloids; Amino Acid Sequence; Bacterial Adhesion; Carbohydrate Sequence; Cell Membrane; Cells, Cultured; Enterobacter cloacae; Fimbriae Proteins; Fimbriae, Bacterial; Indolizines; Lectins; Lectins, C-Type; Mannose Receptor; Mannose-Binding Lectins; Molecular Sequence Data; Oligosaccharides; Peptide Fragments; Protein Binding; Protein Processing, Post-Translational; Receptors, Cell Surface; Sequence Analysis; Sequence Homology, Amino Acid; Swainsonine | 1997 |
Inhibition of hybrid- and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Mannosidase; Animals; Cell Line; CHO Cells; Cricetinae; DNA, Complementary; Enzyme Inhibitors; Fucose; Glycoproteins; Glycosylation; Humans; N-Acetylglucosaminyltransferases; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swainsonine | 2006 |
Man2C1, an alpha-mannosidase, is involved in the trimming of free oligosaccharides in the cytosol.
Topics: Alkaloids; alpha-Mannosidase; Blotting, Western; Cell Line; Chromatography, High Pressure Liquid; Cobalt; Cytosol; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Humans; Immunohistochemistry; Mannosidases; Membrane Glycoproteins; Oligopeptides; Oligosaccharides; Peptides; Recombinant Fusion Proteins; RNA Interference; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swainsonine; Transfection | 2006 |
Glycoprotein structural genomics: solving the glycosylation problem.
Topics: Alkaloids; Cell Line; Cloning, Molecular; Enzyme Inhibitors; Genomics; Glycoproteins; Glycosylation; Humans; Swainsonine | 2007 |
Evolution of cross-neutralizing antibody specificities to the CD4-BS and the carbohydrate cloak of the HIV Env in an HIV-1-infected subject.
Topics: Alkaloids; Antibodies, Monoclonal; Antibodies, Neutralizing; Antibody Specificity; Binding Sites; Carbohydrates; CD4 Antigens; Cross Reactions; env Gene Products, Human Immunodeficiency Virus; Epitopes; HIV Antibodies; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Swainsonine; Time Factors; Virion | 2012 |
N-glycan content modulates kainate receptor functional properties.
Topics: Alkaloids; alpha-Mannosidase; Animals; Female; Glycosylation; HEK293 Cells; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Polysaccharides; Receptors, Kainic Acid; Swainsonine | 2017 |
N-glycan Remodeling Using Mannosidase Inhibitors to Increase High-mannose Glycans on Acid α-Glucosidase in Transgenic Rice Cell Cultures.
Topics: Alkaloids; alpha-Glucosidases; Cells, Cultured; Enzyme Inhibitors; Glycosylation; Humans; Mannose; Mannosidases; Oryza; Plants, Genetically Modified; Polysaccharides; Swainsonine | 2018 |
Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation.
Topics: Alkaloids; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; CHO Cells; Cricetulus; Curcumin; Glycosylation; Humans; Mannosidases; Membrane Glycoproteins; Receptors, Notch; Substrate Specificity; Swainsonine | 2020 |