khellin and sirolimus

khellin has been researched along with sirolimus in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Do, DV; Han, HC; Khoo, YT; Lim, IJ; Mukhopadhyay, A; Ong, CT; Phan, TT; Tan, EK1
Aalami, O; Do, DV; Khoo, YT; Lim, IJ; Mukhopadhyay, A; Ong, CT; Phan, TT1
Bahl, A; Bayat, A; Sanganee, HJ; Singh, S; Syed, F1
Gurtner, GC; Januszyk, M; Kuang, AA; Wong, VW; You, F1
Cao, R; Gao, J; Jiao, H; Sun, X; Xiao, Z; Yan, Z; Yang, Z; Zhuang, Q1

Other Studies

7 other study(ies) available for khellin and sirolimus

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion.
    The Journal of pathology, 2007, Volume: 211, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Differentiation; Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Daunorubicin; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Fibroblasts; Humans; Immunohistochemistry; Keloid; Keratinocytes; Mesoderm; Mitoxantrone; Neovascularization, Pathologic; Sirolimus; Statistics, Nonparametric; Up-Regulation; Vascular Endothelial Growth Factor A; Wound Healing

2007
mTOR as a potential therapeutic target for treatment of keloids and excessive scars.
    Experimental dermatology, 2007, Volume: 16, Issue:5

    Topics: Actins; Adolescent; Adult; Cells, Cultured; Child; Cicatrix, Hypertrophic; Collagen; Cyclin D; Cyclins; Dose-Response Relationship, Drug; Female; Fibroblasts; Fibronectins; Humans; In Vitro Techniques; Keloid; Male; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Kinases; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; TOR Serine-Threonine Kinases

2007
Potent dual inhibitors of TORC1 and TORC2 complexes (KU-0063794 and KU-0068650) demonstrate in vitro and ex vivo anti-keloid scar activity.
    The Journal of investigative dermatology, 2013, Volume: 133, Issue:5

    Topics: Adolescent; Adult; Aged; Cell Movement; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunosuppressive Agents; In Vitro Techniques; Keloid; Male; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Middle Aged; Morpholines; Multiprotein Complexes; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Young Adult

2013
Transcriptional profiling of rapamycin-treated fibroblasts from hypertrophic and keloid scars.
    Annals of plastic surgery, 2014, Volume: 72, Issue:6

    Topics: Adult; Aged; Cicatrix, Hypertrophic; Collagen; Dose-Response Relationship, Drug; Down-Regulation; Female; Fibroblasts; Humans; Immunosuppressive Agents; Keloid; Male; Middle Aged; Phosphorylation; Protein Array Analysis; Sirolimus; TOR Serine-Threonine Kinases

2014
[In vitro study of effects and mechanism of rapamycin-induced autophagy in keloid fibroblasts].
    Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2016, Volume: 32, Issue:3

    Topics: Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Collagen Type I; Fibroblasts; Fibronectins; Humans; Immunosuppressive Agents; Keloid; MicroRNAs; Phosphorylation; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2016
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