kf 4317 has been researched along with labetalol in 2 studies
| Studies (kf 4317) | Trials (kf 4317) | Recent Studies (post-2010) (kf 4317) | Studies (labetalol) | Trials (labetalol) | Recent Studies (post-2010) (labetalol) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 1,980 | 450 | 327 |
| Protein | Taxonomy | kf 4317 (IC50) | labetalol (IC50) |
|---|---|---|---|
| Beta-2 adrenergic receptor | Homo sapiens (human) | 0.016 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 3.354 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.01 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.8 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.393 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 3.354 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.521 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.393 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 3.037 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 1.607 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.815 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doggrell, SA | 1 |
| Hiruta, T; Kizawa, Y; Koike, K; Konno, F; Kusunoki, M; Sato, T; Takayanagi, I; Toyoda, J | 1 |
2 other study(ies) available for kf 4317 and labetalol
| Article | Year |
|---|---|
Relaxant and beta 2-adrenoceptor blocking activities of labetalol, dilevalol, amosulalol and KF-4317 on the rat isolated aorta.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Benzeneacetamides; Ethanolamines; In Vitro Techniques; Labetalol; Male; Muscle, Smooth, Vascular; Procaterol; Propanolamines; Rats; Rats, Inbred Strains | 1988 |
Actions of 4-(2-hydroxy-3-[(1-methyl-3-phenylpropyl)amino]propoxy) benzeneacetamide (KF4317) and labetalol on alpha- and beta-adrenoceptors.
Topics: Animals; Benzeneacetamides; Guinea Pigs; Labetalol; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Propanolamines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1986 |