kf 17837s has been researched along with adenosine in 31 studies
| Studies (kf 17837s) | Trials (kf 17837s) | Recent Studies (post-2010) (kf 17837s) | Studies (adenosine) | Trials (adenosine) | Recent Studies (post-2010) (adenosine) |
|---|---|---|---|---|---|
| 39 | 0 | 0 | 32,536 | 1,075 | 8,930 |
| Protein | Taxonomy | kf 17837s (IC50) | adenosine (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 0.3851 | |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | 5.5 | |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | 5.5 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.0011 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.0023 | |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | 63 | |
| Solute carrier family 28 member 3 | Homo sapiens (human) | 3.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 23 (74.19) | 18.2507 |
| 2000's | 8 (25.81) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kase, H; Kirk, IP; Kirkpatrick, KA; Kurokawa, M; Richardson, PJ | 1 |
| Ichimura, M; Kase, H; Mori, A; Nonaka, H; Shimada, J; Shindou, T; Yanagawa, K | 1 |
| Kanda, T; Nakamura, J; Shimada, J; Shiozaki, S; Suzuki, F | 1 |
| Conti, A; Dionisotti, S; Gatta, F; Ongini, E; Sandoli, D; Zocchi, C | 1 |
| Ichimura, M; Kase, H; Nonaka, H; Nonaka, Y; Shimada, J; Suzuki, F; Takeda, M; Yamaguchi, K | 1 |
| Aoki, N; Kase, H; Kobayashi, H; Koike, N; Nonaka, H; Nonaka, Y; Shimada, J; Suzuki, F; Yamaguchi, K | 1 |
| Herzer, WA; Jackson, EK; Suzuki, F | 1 |
| Karasawa, A; Mori, T; Moriyama, T | 1 |
| Mayfield, RD; Suzuki, F; Zahniser, NR | 1 |
| Abiru, T; Endo, K; Machida, H | 1 |
| Bauer, J; Berger, M; Biber, K; Fiebich, BL; Gyufko, K; van Calker, D | 1 |
| Hayaishi, O; Matsumura, H; Satoh, S; Suzuki, F | 1 |
| Gubitz, AK; Kirkpatrick, KA; Kurokawa, M; Richardson, PJ; Widdowson, L | 1 |
| Constantino, MD; Cunha, RA; Fredholm, BB; Johansson, B; Sebastião, AM | 1 |
| Karasawa, A; Nagashima, K | 1 |
| Cheng, DY; DeWitt, BJ; Kadowitz, PJ; Neely, CF; Suzuki, F | 1 |
| Ikeda, U; Kurosaki, K; Okada, K; Saito, T; Shimada, K; Shimpo, M | 1 |
| Bauer, J; Fiebich, BL; Heese, K; Otten, U | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z | 2 |
| Frobenius, W; Geis, U; Hipp, J; Müller, CE; Pawłowski, M; Sandoval-Ramírez, J; Schobert, U; Suzuki, F | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK | 1 |
| Ikeda, K; Jackson, MJ; Jenner, PG; Kanda, T; Kase, H; Koga, K; Kurokawa, M; Kuwana, Y; Ochi, M; Pearce, RK; Shiozaki, S; Smith, LA | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Keller, PJ; Mi, Z; Rosselli, M | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Shue, H | 1 |
| El Nahas, AM; Fang, L; Haylor, JL; Morcos, SK; Oldroyd, SD; Yates, MS | 1 |
| Agematsu, K; Hokibara, S; Komiyama, A; Nagumo, H; Nakazawa, T; Shinozaki, K; Yasui, K | 1 |
| Inscho, EW; Navar, LG; Nishiyama, A | 1 |
| Chen, Y; Hertz, L; Rathbone, MP | 1 |
| Bivalacqua, TJ; Champion, HC; Kadowitz, PJ; Lambert, DG | 1 |
| Kondo, Y; Morishima, T; Tsuge, M; Wada, T; Yashiro, M; Yasui, K | 1 |
1 review(s) available for kf 17837s and adenosine
| Article | Year |
|---|---|
Antiparkinsonian activity of adenosine A2A antagonists in experimental models.
Topics: Adenosine; Antiparkinson Agents; Humans; Motor Activity; Parkinson Disease; Phenethylamines; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Xanthines | 1999 |
30 other study(ies) available for kf 17837s and adenosine
| Article | Year |
|---|---|
Inhibition by KF17837 of adenosine A2A receptor-mediated modulation of striatal GABA and ACh release.
Topics: Acetylcholine; Adenosine; Animals; Antihypertensive Agents; Female; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Ligands; Male; Neostriatum; Nerve Endings; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Subcellular Fractions; Synaptosomes; Xanthines | 1994 |
Binding of [3H]KF17837S, a selective adenosine A2 receptor antagonist, to rat brain membranes.
Topics: Adenosine; Animals; Autoradiography; Corpus Striatum; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Wistar; Xanthines | 1994 |
KF17837: a novel selective adenosine A2A receptor antagonist with anticataleptic activity.
Topics: Adenosine; Administration, Oral; Animals; Antihypertensive Agents; Benserazide; Catalepsy; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Levodopa; Male; Mice; Phenethylamines; Purinergic Antagonists; Xanthines | 1994 |
Effects of the new A2 adenosine receptor antagonist 8FB-PTP, an 8 substituted pyrazolo-triazolo-pyrimidine, on in vitro functional models.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phosphoric Diester Hydrolases; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Rabbits; Rats; Rats, Sprague-Dawley; Triazoles; Vasodilator Agents; Xanthines | 1994 |
KF17837 ((E)-8-(3,4-dimethoxystyryl)-1,3-dipropyl-7-methylxanthine), a potent and selective adenosine A2 receptor antagonist.
Topics: Adenosine; Animals; Binding, Competitive; Corpus Striatum; Cyclic AMP; Male; PC12 Cells; Phenethylamines; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Wistar; Receptors, Cell Surface; Stereoisomerism; Tumor Cells, Cultured; Xanthines | 1994 |
Photoisomerization of a potent and selective adenosine A2 antagonist, (E)-1,3-Dipropyl-8-(3,4-dimethoxystyryl)-7-methylxanthine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Chromatography, High Pressure Liquid; Isomerism; Kinetics; Phenethylamines; Photochemistry; Prosencephalon; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Xanthines | 1993 |
KF17837 is an A2 adenosine receptor antagonist in vivo.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Heart Rate; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Xanthines | 1993 |
Inhibitory effects of KW-3902, a selective adenosine A1-receptor antagonist, on the adenosine-induced shortening of action potential duration in guinea pig atrial muscles.
Topics: Action Potentials; Adenosine; Animals; Electrophysiology; Guinea Pigs; Heart Atria; Male; Purinergic P1 Receptor Antagonists; Xanthines | 1993 |
Adenosine A2a receptor modulation of electrically evoked endogenous GABA release from slices of rat globus pallidus.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Electric Stimulation; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Kinetics; Male; Phenethylamines; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Theophylline; Time Factors; Xanthines | 1993 |
Differential vasodilatory action of 2-octynyladenosine (YT-146), an adenosine A2 receptor agonist, in the isolated rat femoral artery and vein.
Topics: Adenosine; Alkynes; Animals; Endothelium, Vascular; Femoral Artery; Femoral Vein; Male; Muscle Contraction; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Serotonin; Vasodilator Agents; Xanthines | 1995 |
Adenosine A2b receptors mediate an increase in interleukin (IL)-6 mRNA and IL-6 protein synthesis in human astroglioma cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Antineoplastic Agents; Astrocytoma; Blotting, Northern; Caffeine; Dose-Response Relationship, Immunologic; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; RNA, Messenger; Stereoisomerism; Tumor Cells, Cultured; Xanthines | 1996 |
Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats.
Topics: Adenosine; Animals; Male; Phenethylamines; Prosencephalon; Prostaglandin D2; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Sleep; Xanthines | 1996 |
Dual signalling by the adenosine A2a receptor involves activation of both N- and P-type calcium channels by different G proteins and protein kinases in the same striatal nerve terminals.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine; Agatoxins; Alkaloids; Animals; Antihypertensive Agents; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels; Cholera Toxin; Cholinergic Fibers; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; Isoquinolines; Neostriatum; Neurons; Phenanthridines; Phenethylamines; Piperazines; Potassium; Presynaptic Terminals; Protein Kinase C; Protein Kinases; Rats; Rats, Wistar; Receptors, Purinergic P1; Signal Transduction; Spider Venoms; Stereoisomerism; Sulfonamides; Tritium; Xanthines | 1996 |
Evidence for high-affinity binding sites for the adenosine A2A receptor agonist [3H] CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A2A receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Hippocampus; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Xanthines | 1996 |
Modulation of erythropoietin production by selective adenosine agonists and antagonists in normal and anemic rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Anemia; Animals; Erythropoietin; Hematocrit; Hypoxia; Kinetics; Male; Nephrectomy; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Time Factors; Xanthines | 1996 |
Adenosine A1 and A2 receptors mediate tone-dependent responses in feline pulmonary vascular bed.
Topics: Adamantane; Adenosine; Adenosine Triphosphate; Animals; Arginine; Cats; Female; Male; Methylene Blue; Morpholines; Muscle Tonus; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Pulmonary Circulation; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Xanthines | 1996 |
Adenosine stimulates nitric oxide synthesis in rat cardiac myocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Animals, Newborn; Bucladesine; Cells, Cultured; Dactinomycin; Enzyme Inhibitors; Heart; Humans; Interleukin-1; Isoproterenol; Myocardium; Naphthalenes; Nitric Oxide; Nitrites; omega-N-Methylarginine; Protein Kinase C; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Stereoisomerism; Theophylline; Xanthines | 1997 |
Nerve growth factor (NGF) expression in rat microglia is induced by adenosine A2a-receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Antihypertensive Agents; Bucladesine; Colforsin; Gene Expression; Microglia; Nerve Growth Factors; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1997 |
Exogenous and endogenous adenosine inhibits fetal calf serum-induced growth of rat cardiac fibroblasts: role of A2B receptors.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Cattle; Cell Division; Culture Media; Dipyridamole; DNA Replication; Enzyme Inhibitors; Fibroblasts; Heart; Male; Myocardium; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tubercidin; Xanthines | 1997 |
Synthesis and structure-activity relationships of 3,7-dimethyl-1-propargylxanthine derivatives, A2A-selective adenosine receptor antagonists.
Topics: Adenosine; Animals; Binding, Competitive; Brain; Caffeine; Molecular Structure; Phenethylamines; Protein Binding; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theobromine; Xanthines | 1997 |
Adenosine inhibits growth of human aortic smooth muscle cells via A2B receptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adult; Animals; Aorta, Thoracic; Cell Division; Cells, Cultured; Collagen; Dipyridamole; DNA; Humans; Kinetics; Male; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A2B; Receptors, Purinergic P1; Thymidine; Xanthines | 1998 |
Adenosine inhibits collagen and total protein synthesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Aorta, Abdominal; Cells, Cultured; Collagen; Cyclic AMP; Dipyridamole; Kinetics; Leucine; Male; Muscle, Smooth, Vascular; Proline; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Xanthines | 1999 |
Estradiol inhibits smooth muscle cell growth in part by activating the cAMP-adenosine pathway.
Topics: Adenosine; Adenylyl Cyclases; Animals; Antihypertensive Agents; Aorta; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; DDT; Enzyme Inhibitors; Estradiol; Fetal Proteins; Male; Muscle, Smooth, Vascular; Proline; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Thionucleotides; Thymidine; Tritium; Xanthines | 2000 |
A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticoagulants; Antihypertensive Agents; Aorta, Abdominal; Becaplermin; Cell Division; Dinucleoside Phosphates; Enzyme Inhibitors; Hyperplasia; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Phenethylamines; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Thymidine; Tritium; Tubercidin; Vasodilator Agents; Xanthines | 2000 |
Effects of adenosine receptor antagonists on the responses to contrast media in the isolated rat kidney.
Topics: Adenosine; Analysis of Variance; Animals; Contrast Media; Diatrizoate; Glomerular Filtration Rate; Kidney; Male; Perfusion; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline; Triiodobenzoic Acids; Xanthines | 2000 |
Theophylline induces neutrophil apoptosis through adenosine A2A receptor antagonism.
Topics: Adenosine; Apoptosis; Carbazoles; Cells, Cultured; Humans; Indoles; Neutrophils; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrroles; Receptor, Adenosine A2A; Signal Transduction; Theophylline; Xanthines | 2000 |
Interactions of adenosine A1 and A2a receptors on renal microvascular reactivity.
Topics: Adenosine; Animals; Arterioles; Extracellular Space; Male; Microcirculation; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Renal Circulation; Vasomotor System; Xanthines | 2001 |
Guanosine-induced increase in free cytosolic calcium concentration in mouse astrocytes in primary cultures: does it act on an A3 adenosine receptor?
Topics: Adenosine; Animals; Astrocytes; Brain; Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Extracellular Space; Guanosine; Mice; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Theophylline; Triazoles; Xanthines | 2001 |
Vasodilator responses to adenosine and hyperemia are mediated by A(1) and A(2) receptors in the cat vascular bed.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cats; Dose-Response Relationship, Drug; Female; Hemodynamics; Hindlimb; Hyperemia; Male; Perfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Triazoles; Vascular Resistance; Vasodilation; Xanthines | 2002 |
Theophylline inhibits the differentiation of human monocyte into dendritic cell potentially via adenosine receptor antagonism.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Adult; Apoptosis; Caspase 3; CD11c Antigen; Cell Differentiation; Dendritic Cells; Granulocyte-Macrophage Colony-Stimulating Factor; HLA-DR Antigens; Humans; Interleukin-4; Male; Monocytes; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptors, Purinergic P1; Recombinant Proteins; RNA, Small Interfering; Rolipram; Theophylline; Xanthines | 2009 |