ketotifen-fumarate and 1--acetoxychavicol-acetate

ketotifen-fumarate has been researched along with 1--acetoxychavicol-acetate* in 1 studies

Other Studies

1 other study(ies) available for ketotifen-fumarate and 1--acetoxychavicol-acetate

Article	Year
Acetoxybenzhydrols as highly active and stable analogues of 1'S-1'-acetoxychavicol, a potent antiallergic principal from Alpinia galanga. Bioorganic & medicinal chemistry letters, 2009, Jun-01, Volume: 19, Issue:11 Through SAR studies on 1'S-1'-acetoxychavicol acetate (1) against Type I antiallergic activity by indexing release of beta-hexosaminidase, a marker of antigen-IgE-mediated degranulation in RBL-2H3 cells, more stable and potent analogue, 4-(methoxycarbonyloxyphenylmethyl)phenyl acetate (16), has been developed. The compound 16 also strongly inhibited the antigen-IgE-mediated TNF-alpha and IL-4 production. Topics: Alpinia; Animals; Anti-Allergic Agents; Benzyl Alcohols; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Immunoglobulin E; Interleukin-4; Phenylacetates; Rats; Structure-Activity Relationship; Tumor Necrosis Factor-alpha	2009

Article

Year

Acetoxybenzhydrols as highly active and stable analogues of 1'S-1'-acetoxychavicol, a potent antiallergic principal from Alpinia galanga.

Bioorganic & medicinal chemistry letters, 2009, Jun-01, Volume: 19, Issue:11

Through SAR studies on 1'S-1'-acetoxychavicol acetate (1) against Type I antiallergic activity by indexing release of beta-hexosaminidase, a marker of antigen-IgE-mediated degranulation in RBL-2H3 cells, more stable and potent analogue, 4-(methoxycarbonyloxyphenylmethyl)phenyl acetate (16), has been developed. The compound 16 also strongly inhibited the antigen-IgE-mediated TNF-alpha and IL-4 production.

Topics: Alpinia; Animals; Anti-Allergic Agents; Benzyl Alcohols; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Immunoglobulin E; Interleukin-4; Phenylacetates; Rats; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2009