ketorolac has been researched along with naproxen in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.14) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 7 (25.00) | 29.6817 |
| 2010's | 15 (53.57) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, MR; D'Ambra, TE; Daum, SJ; Eissenstat, MA; Herrmann, JL; Hlasta, DJ; Kumar, V; Philion, RE; Rosi, D; Wetzel, JR | 1 |
| Ackerman, N; Ballaron, SA; Galeazzi, E; Greenhouse, R; Guzmán, A; Muchowski, JM; Peréz, V; Rovito, JR; Tomolonis, AJ; Young, JM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Jones, TA; Nakagawa, A; Smith, CE; Soti, S; Xue, D; Yin, H | 1 |
| Corona, L; Iovinelli, G; Paladini, A; Panella, G; Varrassi, G | 1 |
| Gasparich, JP; Mayo, ME | 1 |
| Goldstein, JL; Harris, SI; Hubbard, RC; Kuss, M | 1 |
| Browning, RA; Burgess, FW | 1 |
| Costa, D; Fernandes, E; Gomes, A; Lima, JL | 1 |
| Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC | 1 |
| Cairns, BE; Dong, XD; Svensson, P; Wong, H | 1 |
| Nalamachu, S; Wortmann, R | 1 |
| Agola, JO; Guo, Y; Hudson, LG; Murray-Krezan, C; Oprea, TI; Romero, E; Roxby, J; Silberberg, M; Sklar, LA; Surviladze, Z; Ursu, O; Vestling, A; Waller, A; Wandinger-Ness, A | 1 |
| Ainslie, PN; Bain, AR; Hoiland, RL; Monteleone, B; Tymko, MM; Wildfong, KW | 1 |
| Amazonas, RB; Bocchi de Oliveira, MF; Ecclissato, Cda C; Plapler, PG; Scheinberg, MA | 1 |
| Peña, S; Wilkin, Z | 1 |
| Gorenflo, M; Saur, P; van den Anker, JN; van Dyk, M; Welzel, T; Ziesenitz, VC | 1 |
3 review(s) available for ketorolac and naproxen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Role of indomethacin in acute pain and inflammation management: a review of the literature.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Humans; Indomethacin; Inflammation; Ketorolac; Naproxen; Oxycodone; Piroxicam; Tramadol; Treatment Outcome | 2014 |
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain | 2022 |
2 trial(s) available for ketorolac and naproxen
| Article | Year |
|---|---|
Upper gastrointestinal safety evaluation of parecoxib sodium, a new parenteral cyclooxygenase-2-specific inhibitor, compared with ketorolac, naproxen, and placebo.
Topics: Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Gastric Mucosa; Humans; Infusions, Parenteral; Isoenzymes; Isoxazoles; Ketorolac; Male; Membrane Proteins; Naproxen; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases | 2001 |
Carbon dioxide-mediated vasomotion of extra-cranial cerebral arteries in humans: a role for prostaglandins?
Topics: Adolescent; Adult; Carbon Dioxide; Carotid Artery, Internal; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Humans; Hypercapnia; Hypocapnia; Indomethacin; Ketorolac; Male; Middle Cerebral Artery; Naproxen; Prostaglandins; Single-Blind Method; Ultrasonography, Doppler, Duplex; Vasoconstriction; Vasodilation; Young Adult | 2016 |
23 other study(ies) available for ketorolac and naproxen
| Article | Year |
|---|---|
Antinociceptive (aminoalkyl)indoles.
Topics: Analgesia; Analgesics; Animals; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Indoles; Magnetic Resonance Spectroscopy; Male; Methylation; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Vas Deferens | 1991 |
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-ca rboxyl ic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids.
Topics: Acetates; Analgesia; Animals; Aspirin; Benzoquinones; Carboxylic Acids; Carrageenan; Chemical Phenomena; Chemistry; Edema; Inflammation; Mice; Molecular Structure; Pain Measurement; Phenylbutazone; Pyrroles; Quinones; Rats | 1989 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caspase Inhibitors; Caspases; Caspases, Initiator; Cell Line; Cell Survival; High-Throughput Screening Assays; Humans; Ibuprofen; Inhibitory Concentration 50; Ketorolac; Naproxen; Small Molecule Libraries; Substrate Specificity | 2017 |
[Ketorolac vs naproxen in the treatment of primary dysmenorrhea].
Topics: Adolescent; Adult; Analgesics; Dysmenorrhea; Female; Humans; Ketorolac; Naproxen; Severity of Illness Index; Tolmetin | 1991 |
Comparative effects of four prostaglandin synthesis inhibitors on the obstructed kidney in the dog.
Topics: Animals; Blood Pressure; Dogs; Female; Ibuprofen; Indomethacin; Ketorolac; Kidney Pelvis; Naproxen; Pressure; Prostaglandin Antagonists; Tolmetin; Ureteral Obstruction | 1986 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Etodolac; Humans; Ibuprofen; Indomethacin; Ketorolac; Lactones; Nabumetone; Naproxen; Pain, Postoperative; Piroxicam; Pyrazoles; Sulfonamides; Sulfones; Time Factors | 2001 |
Singlet oxygen scavenging activity of non-steroidal anti-inflammatory drugs.
Topics: Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dose-Response Relationship, Drug; Etodolac; Free Radical Scavengers; Indoprofen; Ketorolac; Molecular Structure; Naproxen; Oxaprozin; Propionates; Singlet Oxygen; Tolmetin | 2008 |
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts | 2012 |
Intramuscular ketorolac inhibits activation of rat peripheral NMDA receptors.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Excitatory Amino Acid Agonists; Female; Injections, Intramuscular; Ketorolac; Male; Naproxen; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Trigeminal Nerve | 2012 |
Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Movement; Cell Survival; HeLa Cells; Humans; Immunoblotting; Ketorolac; Mice; Microscopy, Confocal; Molecular Docking Simulation; Molecular Structure; Naproxen; NIH 3T3 Cells; Protein Binding; Protein Structure, Tertiary; rac1 GTP-Binding Protein; Stereoisomerism | 2015 |
Double-blind, randomized, double-dummy clinical trial comparing the efficacy of ketorolac trometamol and naproxen for acute low back pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ketorolac; Low Back Pain; Naproxen; Tromethamine | 2016 |
Acute abdominal pain from epiploic appendagitis.
Topics: Abdomen, Acute; Acetaminophen; Adult; Colitis; Conservative Treatment; Humans; Hydromorphone; Ketorolac; Male; Naproxen; Pain Management; Sigmoid Diseases; Tomography, X-Ray Computed; Treatment Outcome | 2020 |