Compounds > ketorolac

ketorolac and naloxone

ketorolac has been researched along with naloxone in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (10.53)	18.2507
2000's	6 (31.58)	29.6817
2010's	11 (57.89)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Campillo, NE; Guerra, A; Páez, JA	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Castañeda-Hernández, G; Flores-Murrieta, FJ; Granados-Soto, V; Hong, E; López-Muñoz, FJ	1
Miranda, HF; Pinardi, G; Sierralta, F	1
Rattan, AK; Tejwani, GA	1
Dunbar, SA; Karamian, I; Zhang, J	1
Deveci, MS; Dogrul, A; Gul, H; Gülmez, SE; Ossipov, MH; Porreca, F; Tulunay, FC	1
Tsagareli, MG; Tsiklauri, N; Viatchenko-Karpinski, V; Voitenko, N	1
Abzianidze, E; Gurtskaia, G; Nozadze, I; Tsagareli, MG; Tsiklauri, N	1
Gurtskaia, G; Nebieridze, M; Nozadze, I; Tsagareli, MG; Tsiklauri, N	1
Benner, RW; Freeman, H; Isaacs, AN; Nisly, SA; O'Sullivan, JA; Schwinghammer, AJ	1
Abzianidze, E; Gorgiladze, T; Nozadze, I; Tsagareli, M	1
Abzianidze, E; Gurtskaia, G; Nebieridze, M; Nozadze, I; Pirkulashvili, N; Tsagareli, MG; Tsiklauri, N	1
Kvachadze, I; Tsagareli, M; Tsagareli, N; Tsiklauri, N	1

Reviews

1 review(s) available for ketorolac and naloxone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

18 other study(ies) available for ketorolac and naloxone

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Evidence against the participation of mu- and kappa-opioid receptors in the analgesic activity of ketorolac in rats. The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:6 Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Ethylketocyclazocine; Female; Ketorolac; Morphine; Movement Disorders; Naloxone; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Time Factors; Tolmetin	1995
Previous administration of indomethacin or naloxone did not influence ketorolac antinociception in mice. Anesthesia and analgesia, 1993, Volume: 77, Issue:4 Topics: Animals; Cecum; Cerebral Ventricles; Indomethacin; Injections, Intraperitoneal; Ketorolac; Mice; Naloxone; Time Factors; Tolmetin	1993
Antagonism of antinociception produced by intrathecal clonidine by ketorolac in the rat: the role of the opioid system. Anesthesia and analgesia, 2000, Volume: 90, Issue:5 Topics: Adrenergic alpha-Agonists; Analgesia; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Injections, Spinal; Ketorolac; Male; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Cord	2000
Ketorolac prevents recurrent withdrawal induced hyperalgesia but does not inhibit tolerance to spinal morphine in the rat. European journal of pain (London, England), 2007, Volume: 11, Issue:1 Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Hyperalgesia; Injections, Spinal; Ketorolac; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Pain Measurement; Pain, Intractable; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance Withdrawal Syndrome	2007
The local antinociceptive actions of nonsteroidal antiinflammatory drugs in the mouse radiant heat tail-flick test. Anesthesia and analgesia, 2007, Volume: 104, Issue:4 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Dipyrone; Disease Models, Animal; Dose-Response Relationship, Drug; Hot Temperature; Injections, Intradermal; Injections, Intraperitoneal; Ketorolac; Lysine; Male; Mice; Mice, Inbred BALB C; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Reaction Time; Sodium Salicylate; Tail; Time Factors	2007
Non-opioid tolerance in juvenile and adult rats. European journal of pharmacology, 2010, Mar-10, Volume: 629, Issue:1-3 Topics: Age Factors; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Drug Tolerance; Ketorolac; Morphine; Naloxone; Piroxicam; Rats; Time Factors	2010
Opioid sensitivity of nucleus raphe magnus ater analgesia by nonsteroidal anti-inflammatory drugs. Georgian medical news, 2011, Issue:190 Topics: Analgesia; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Drug Interactions; Drug Tolerance; Ketorolac; Male; Microinjections; Morphine; Naloxone; Nociceptors; Pain; Periaqueductal Gray; Piroxicam; Raphe Nuclei; Rats; Spinal Cord	2011
Antinociceptive tolerance to NSAIDs microinjected into dorsal hippocampus. BMC pharmacology & toxicology, 2014, Feb-28, Volume: 15 Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Diclofenac; Drug Resistance; Hippocampus; Ketorolac; Male; Microinjections; Naloxone; Narcotic Antagonists; Pain; Piroxicam; Rats; Rats, Wistar	2014
Continuous Infusion Ketorolac for Postoperative Analgesia Following Unilateral Total Knee Arthroplasty. The Annals of pharmacotherapy, 2017, Volume: 51, Issue:6 Topics: Aged; Analgesia; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Female; Humans; Ketorolac; Male; Middle Aged; Naloxone; Pain Management; Pain Measurement; Pain, Postoperative; Retrospective Studies	2017
NON-STEROIDAL ANTI-INFLAMMATORY DRUGS'S ANTINOCICEPTION MEDIATED BY THE OPIOID MECHANISM IN THE NUCLEUS RAPHE MAGNUS. Georgian medical news, 2017, Issue:265 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dipyrone; Ketorolac; Male; Microinjections; Naloxone; Narcotic Antagonists; Nociception; Nucleus Raphe Magnus; Opioid Peptides; Piroxicam; Rats; Reaction Time	2017
Antinociceptive tolerance to NSAIDs in the anterior cingulate cortex is mediated via endogenous opioid mechanism. BMC pharmacology & toxicology, 2018, 01-06, Volume: 19, Issue:1 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Tolerance; Gyrus Cinguli; Ketorolac; Male; Microinjections; Naloxone; Narcotic Antagonists; Opioid Peptides; Pain; Piroxicam; Rats, Wistar	2018
NALOXONE AND CTOP BLOCK NSAIDS-INDUCED ANTINOCICEPTION IN ANTERIOR CINGULATE CORTEX OF RATS. Georgian medical news, 2019, Issue:286 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Gyrus Cinguli; Ketorolac; Naloxone; Narcotic Antagonists; Pain Perception; Rats; Rats, Wistar; Somatostatin	2019