ketorolac and ketorolac tromethamine

ketorolac has been researched along with ketorolac tromethamine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.71)18.7374
1990's8 (28.57)18.2507
2000's4 (14.29)29.6817
2010's4 (14.29)24.3611
2020's9 (32.14)2.80

Authors

AuthorsStudies
Cabrita, EJ; Corvo, MC; Manso, J; Marques, MM; Viegas, A1
Bynum, L; Jung, D; Massey, I; Mroszczak, EJ; Sevelius, H; Yee, J1
Bynum, L; Jung, D; Ling, TL; Mroszczak, EJ; Sevelius, H; Wu, A1
Davidson, GW; Ling, T; Marvin, MJ; Sanders, LM; Yu, D1
Maloney, PJ; Rooks, WH; Schuler, ME; Sevelius, H; Shott, LD; Strosberg, AM; Tanenbaum, L; Tomolonis, AJ; Wallach, MB; Waterbury, D1
Goodwin, AP; Millett, S; Old, S; Parke, TJ; Rice, AS1
Brandl, M; Conley, D; Johnson, D1
Fiscella, RG; Rabiah, PK; Tessler, HH1
Manoukian, E; Roy, SD1
Agostinis, L; Cattaruzzi, C; García Rodríguez, LA; Troncon, MG1
Majumdar, DK; Malhotra, M1
Blair, GA; D'Amico, F; Larkin, GL; Peacock, WF; Pearl, SM1
Avram, MJ; Dsida, RM; Wang, Z1
Aquilino, M; Bonaccorsi, A; Guzzardi, F; Lazzara, A; Motta, M; Saita, A1
Chu, CC; Feng, PH; Ho, ST; Hou, CH; Shieh, JP; Tzeng, JI; Wang, JJ1
Chu, CC; Hou, CH; Shieh, JP; Tzeng, JI; Wang, JJ; Wang, LK; Wang, PJ1
Adams, SF; Bedrick, E; Cook, L; Guo, Y; Hudson, LG; Kang, H; Kenney, SR; Lomo, L; Muller, CY; Oprea, TI; Romero, E; Rutledge, T; Sklar, LA; Wandinger-Ness, A; Wiggins, CL1
Allegaert, K; De Hoon, J; Deprest, J; Kulo, A; Maleškić, S; Smits, A; Van Calsteren, K; Van de Velde, M; Verbesselt, R1
Chapman, GC; El-Nashar, SA; Hijaz, AK; Mahajan, ST; Mangel, J; Petrikovets, A; Pollard, RR; Sheyn, D; Sun, HH1
Allegaert, K; Cloesmeijer, ME; Daali, Y; Lynn, AM; Mian, P; Olkkola, KT; Smits, A; Tibboel, D; van Esdonk, MJ1
Ahmadi, A; Bahreini, M; Eidinejad, L; Mirfazaelian, H; Thiruganasambandamoorthy, V; Yazdchi, M1
Khan, A; Ludvigson, A; Motamedinia, P; Syed, JS; Van-Ryn, MG1
Abdeltawab, H; Bolam, SM; Hill, A; Jaiswal, JK; McGlashan, SR; Sharma, M; Svirskis, D; Young, SW1
Cai, Z; Fu, B; Kang, Y; Li, Y; Wang, J; Wu, Y1
Flores, H; Garrett, M; Kee, M; Magee, T; Modi, J; Roberts, W; Rucker, B; Vassar, M; Wise, A1
Bahreini, R; Emamverdi, M; Karimi, S; Kheiri, B; Mohammad-Rabei, H; Nikkhah, H; Ramezani, A; Sabbaghi, H; Sheibani, K; Yaseri, M1
Fazal, M; Rao, U1
Abdelkader, H; Fatease, AA; Fathalla, Z1

Reviews

2 review(s) available for ketorolac and ketorolac tromethamine

ArticleYear
Ketorolac tromethamine pharmacokinetics and metabolism after intravenous, intramuscular, and oral administration in humans and animals.
    Pharmacotherapy, 1990, Volume: 10, Issue:6 ( Pt 2)

    Topics: Administration, Oral; Aluminum Hydroxide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Female; Food; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Ketorolac; Ketorolac Tromethamine; Magnesium Hydroxide; Male; Metabolic Clearance Rate; Tissue Distribution; Tolmetin; Tromethamine

1990
Impact of enantiomer-specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac: A pooled analysis.
    British journal of clinical pharmacology, 2021, Volume: 87, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Infant; Ketorolac; Ketorolac Tromethamine; Pharmaceutical Preparations; Stereoisomerism

2021

Trials

11 trial(s) available for ketorolac and ketorolac tromethamine

ArticleYear
Pharmacokinetics of ketorolac and p-hydroxyketorolac following oral and intramuscular administration of ketorolac tromethamine.
    Pharmaceutical research, 1989, Volume: 6, Issue:1

    Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Drug Combinations; Humans; Injections, Intramuscular; Ketorolac; Ketorolac Tromethamine; Male; Pyrroles; Random Allocation; Tolmetin; Tromethamine

1989
Ketorolac for early postoperative analgesia.
    Journal of clinical anesthesia, 1995, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Bone and Bones; Double-Blind Method; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Ketorolac; Ketorolac Tromethamine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Tolmetin; Tromethamine

1995
Transdermal delivery of ketorolac tromethamine: permeation enhancement, device design, and pharmacokinetics in healthy humans.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:10

    Topics: 1-Propanol; Administration, Cutaneous; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane Permeability; Chemistry, Pharmaceutical; Delayed-Action Preparations; Humans; Hydrogen-Ion Concentration; Ketorolac; Ketorolac Tromethamine; Myristates; Pharmaceutical Vehicles; Skin; Skin Absorption; Solubility; Tolmetin; Tromethamine

1995
Efficacy of ketorolac tromethamine versus meperidine in the ED treatment of acute renal colic.
    The American journal of emergency medicine, 1999, Volume: 17, Issue:1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Colic; Double-Blind Method; Emergency Treatment; Female; Humans; Ketorolac; Ketorolac Tromethamine; Male; Meperidine; Middle Aged; Pain Measurement; Prospective Studies; Time Factors; Tolmetin; Tromethamine; Ureteral Calculi; Urography

1999
A Novel Pharmacologic Activity of Ketorolac for Therapeutic Benefit in Ovarian Cancer Patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Nov-15, Volume: 21, Issue:22

    Topics: Aged; cdc42 GTP-Binding Protein; Disease-Free Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Ketorolac; Ketorolac Tromethamine; Middle Aged; Ovarian Neoplasms; Paclitaxel; rac1 GTP-Binding Protein

2015
Enantiomer-specific ketorolac pharmacokinetics in young women, including pregnancy and postpartum period.
    Bosnian journal of basic medical sciences, 2017, Feb-21, Volume: 17, Issue:1

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Case-Control Studies; Cesarean Section; Chromatography, High Pressure Liquid; Cohort Studies; Female; Healthy Volunteers; Humans; Injections, Intravenous; Ketorolac; Ketorolac Tromethamine; Postpartum Period; Pregnancy; Stereoisomerism; Time Factors

2017
Multimodal opioid-sparing postoperative pain regimen compared with the standard postoperative pain regimen in vaginal pelvic reconstructive surgery: a multicenter randomized controlled trial.
    American journal of obstetrics and gynecology, 2019, Volume: 221, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Cryotherapy; Drug Utilization; Female; Gynecologic Surgical Procedures; Humans; Hydromorphone; Ketorolac; Ketorolac Tromethamine; Middle Aged; Pain, Postoperative; Patient Satisfaction; Visual Analog Scale

2019
Comparison of intravenous ketorolac at three doses for treating renal colic in the emergency department: A noninferiority randomized controlled trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2021, Volume: 28, Issue:7

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Emergency Service, Hospital; Humans; Ketorolac; Ketorolac Tromethamine; Renal Colic

2021
Toradol to Reduce Ureteroscopy Symptoms Trial (TRUST).
    Urology, 2022, Volume: 165

    Topics: Analgesics, Opioid; Humans; Ketorolac; Ketorolac Tromethamine; Nephrolithiasis; Pain, Postoperative; Ureteroscopy

2022
Effect of ketorolac tromethamine combined with dezocine prior administration on hemodynamics and postoperative analgesia in patients undergoing laparoscopic hernia repair.
    Medicine, 2022, May-20, Volume: 101, Issue:20

    Topics: Aged; Aged, 80 and over; Analgesia; Bridged Bicyclo Compounds, Heterocyclic; Hemodynamics; Hernia, Inguinal; Herniorrhaphy; Humans; Ketorolac; Ketorolac Tromethamine; Laparoscopy; Male; Middle Aged; Propofol; Remifentanil; Sufentanil; Tetrahydronaphthalenes

2022
The effect of topical ketorolac tromethamine on macular thickening after phacoemulsification in diabetic patients.
    BMC ophthalmology, 2023, Jul-14, Volume: 23, Issue:1

    Topics: Diabetes Mellitus; Diabetic Retinopathy; Humans; Ketorolac; Ketorolac Tromethamine; Macular Edema; Phacoemulsification; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity

2023

Other Studies

15 other study(ies) available for ketorolac and ketorolac tromethamine

ArticleYear
Binding of ibuprofen, ketorolac, and diclofenac to COX-1 and COX-2 studied by saturation transfer difference NMR.
    Journal of medicinal chemistry, 2011, Dec-22, Volume: 54, Issue:24

    Topics: Animals; Binding, Competitive; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Female; Ibuprofen; Ketorolac; Magnetic Resonance Spectroscopy; Male; Sheep

2011
Percutaneous absorption of nicardipine and ketorolac in rhesus monkeys.
    Pharmaceutical research, 1988, Volume: 5, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chromatography, High Pressure Liquid; Ketorolac; Ketorolac Tromethamine; Macaca mulatta; Nicardipine; Pharmaceutical Vehicles; Pyrroles; Skin Absorption; Solubility; Tolmetin; Tromethamine

1988
The analgesic and anti-inflammatory profile of ketorolac and its tromethamine salt.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:8

    Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Creatine Kinase; Dogs; Drug Combinations; Eye; Guinea Pigs; Humans; Injections, Intramuscular; Irritants; Ketorolac; Ketorolac Tromethamine; Macaca mulatta; Male; Pyrroles; Rabbits; Rats; Rats, Inbred Strains; Tolmetin; Tromethamine

1985
Racemization of ketorolac in aqueous solution.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:9

    Topics: Catalysis; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Ketorolac; Ketorolac Tromethamine; Kinetics; Solubility; Solutions; Stereoisomerism; Temperature; Tolmetin; Tromethamine

1995
Intraocular penetration of periocular ketorolac and efficacy in experimental uveitis.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Conjunctiva; Disease Models, Animal; Female; Injections, Intramuscular; Ionophores; Ketorolac; Ketorolac Tromethamine; Ophthalmic Solutions; Orbit; Rabbits; Recombinant Proteins; Tolmetin; Tromethamine; Tumor Necrosis Factor-alpha; Uveitis; Vitreous Body

1996
Risk of hospitalization for upper gastrointestinal tract bleeding associated with ketorolac, other nonsteroidal anti-inflammatory drugs, calcium antagonists, and other antihypertensive drugs.
    Archives of internal medicine, 1998, Jan-12, Volume: 158, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Calcium Channel Blockers; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Ketorolac; Ketorolac Tromethamine; Male; Middle Aged; Risk; Risk Factors; Time Factors; Tolmetin; Tromethamine

1998
In vitro transcorneal permeation of ketorolac from oil based ocular drops and ophthalmic ointment.
    Indian journal of experimental biology, 1997, Volume: 35, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Goats; In Vitro Techniques; Ketorolac; Ketorolac Tromethamine; Oils; Ophthalmic Solutions; Permeability; Tolmetin

1997
Determination of ketorolac in human plasma by reversed-phase high-performance liquid chromatography using solid-phase extraction and ultraviolet detection.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, May-05, Volume: 755, Issue:1-2

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Humans; Ketorolac; Ketorolac Tromethamine; Male

2001
ESWL: Comparing two analgesic techniques. Our experience.
    Urologia internationalis, 2004, Volume: 72 Suppl 1

    Topics: Administration, Topical; Adult; Aged; Analgesia; Betamethasone; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Ketorolac; Ketorolac Tromethamine; Kidney Calculi; Lidocaine; Lithotripsy; Male; Middle Aged; Pain Measurement; Prilocaine; Prospective Studies; Radiography; Treatment Outcome; Ureteral Calculi

2004
The antinociceptive and anti-inflammatory effects of a long-acting depot formulated ketorolac in rats.
    Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2005, Volume: 43, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Ketorolac; Ketorolac Tromethamine; Male; Rats; Rats, Sprague-Dawley

2005
The antinociceptive and anti-inflammatory effects of five depot formulations of ketorolac propyl ester in rats.
    Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2005, Volume: 43, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Ketorolac; Ketorolac Tromethamine; Male; Plant Oils; Prodrugs; Rats; Rats, Sprague-Dawley

2005
In situ gelling system for sustained intraarticular delivery of bupivacaine and ketorolac in sheep.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2022, Volume: 174

    Topics: Animals; Bupivacaine; Gels; Ketorolac; Ketorolac Tromethamine; Pain, Postoperative; Poloxamer; Sheep

2022
An analysis of harms reporting in systematic reviews regarding ketorolac for management of perioperative pain.
    British journal of anaesthesia, 2022, Volume: 129, Issue:5

    Topics: Analgesics, Opioid; Humans; Ketorolac; Ketorolac Tromethamine; Pain; Research Design; Systematic Reviews as Topic

2022
Efficacy of Oral Toradol (Ketorolac) Compared to Oral Tramadol as a Preemptive Analgesic in Impacted Third Molar Surgery.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2023, Volume: 33, Issue:8

    Topics: Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ketorolac; Ketorolac Tromethamine; Molar, Third; Pain, Postoperative; Tooth Extraction; Tooth, Impacted; Tramadol

2023
Preformulation-Assisted Design of Ketorolac Tromethamine for Effective Ophthalmic Delivery.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2023, Volume: 39, Issue:10

    Topics: Alkalies; Anti-Inflammatory Agents, Non-Steroidal; Ketorolac; Ketorolac Tromethamine; Lipids; Ophthalmic Solutions; Water

2023