ketorolac and indomethacin

ketorolac has been researched along with indomethacin in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.70)18.7374
1990's11 (20.37)18.2507
2000's19 (35.19)29.6817
2010's20 (37.04)24.3611
2020's2 (3.70)2.80

Authors

AuthorsStudies
Bell, MR; D'Ambra, TE; Daum, SJ; Eissenstat, MA; Herrmann, JL; Hlasta, DJ; Kumar, V; Philion, RE; Rosi, D; Wetzel, JR1
Ackerman, N; Ballaron, SA; Galeazzi, E; Greenhouse, R; Guzmán, A; Muchowski, JM; Peréz, V; Rovito, JR; Tomolonis, AJ; Young, JM1
Topliss, JG; Yoshida, F1
Chilmonczyk, Z; Cybulski, J; Dubis, AT; Kaliszan, R; Lachowska, B; Lozowicka, B; Petrusewicz, J; Poplawski, J; Siluk, D; Strzałkowska, M; Witkowski, S1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A1
Jolivette, LJ; Ward, KW1
Jolivette, LJ; Nagilla, R; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barton, P; Luker, T; Wenlock, MC1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Kumar, M; Sinha, VR; Thareja, S1
Bellman, K; Knegtel, RM; Settimo, L1
Abdelazeem, AH; Khan, SI; McCurdy, CR; Sufka, KJ; White, SW1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gasparich, JP; Mayo, ME1
Foks, H; Kaliszan, R; Petrusewicz, J; Pilarski, B; Turowski, M1
Miranda, HF; Pinardi, G; Sierralta, F1
Cook, MJ; Morley-Forster, P; Newton, PT1
Butler, PO; El-Beheiry, H; Forse, A; Pace, RF1
Anson, N; Turner, GA; Williamson, R1
Hughes, PJ; Leake, T; Murrell, GC1
Boeckxstaens, GE; De Man, JG; De Winter, BY; Herman, AG; Moreels, TG; Pelckmans, PA1
Chatterjee, A; Frangouli, A; Kinsey, J; Morgan, PB; Shah, S1
Barragán, M; Bellosillo, B; Castaño, E; Colomer, D; Gil, J; Montserrat, E; Piqué, M; Pons, G; Villamor, N1
Fernández, AG; Godessart, N; Palacios, JM; Salcedo, C1
Aragona, P; Ferreri, G; Laganà, E; Spinella, R; Tripodi, G1
Browning, RA; Burgess, FW1
Terrell, KM; Weaver, CS1
Chang, JK; Chuang, LY; Ho, ML; Wang, GJ1
Bertolotto, M; Calderan, L; Gasparini, C; Pozzi Mucelli, R; Quaia, E1
Blais, V; Rivest, S; Turrin, NP1
Macedo, GM; Medeiros, BA; Nobre-e-Souza, MA; Palheta-Junior, RC; Santos, AA; Santos, CL; Souza, MH; Troncon, LE1
Coyle, TL; Jerde, TJ; Nakada, SY; Wen, CC1
Chang, JK; Ho, ML; Li, CJ; Liao, HJ; Wang, CK; Wang, GJ1
Aranda, JV; Beharry, KD; Valencia, GB1
Keller, DL1
Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC1
Bunce, C; Crosby-Nwaobi, R; Sivaprasad, S1
Nalamachu, S; Wortmann, R1
Hsu, JR; Noel, SP; Rathbone, CR; Rivera, JC; Wenke, JC1
Ainslie, PN; Bain, AR; Hoiland, RL; Monteleone, B; Tymko, MM; Wildfong, KW1
Araiza-Saldaña, CI; Baños-González, MA; Castañeda-Corral, G; Guzmán-Priego, CG; Méndez-Mena, R; Torres-López, JE1
Amayem, A; Brown, MD; Ghandour, O; Harrison, N; Lang, E; Lawrenson, AL; Lawrenson, JG; McCormick, R; Quirke, M; Wakai, A; Walsh, CD; Wang, Y1
Arfè, A; Castellsague, J; Garbe, E; Herings, R; Kollhorst, B; Lucchi, S; Masclee, GMC; Perez-Gutthann, S; Romio, S; Schade, R; Schink, T; Schuemie, MJ; Scotti, L; Straatman, H; Sturkenboom, MCJM; Valkhoff, VE; Varas-Lorenzo, C; Villa, M1
de Necochea-Campion, R; Elsissy, JG; Frames, WL; Mirshahidi, HR; Mirshahidi, S; Shields, TG; Williams, NL; Zuckerman, LM1
Baeza-Flores, GDC; Martínez-Martínez, MDC; Parra-Flores, LI; Torres-López, JE1
Blake, L; Carvalho, B; Carver, AL; Desai, N; Murdoch, I; O'Carroll, JE; Onwochei, DN; Sultan, P1

Reviews

7 review(s) available for ketorolac and indomethacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Evidence-based emergency medicine. Update: do ophthalmic nonsteroidal anti-inflammatory drugs reduce the pain associated with simple corneal abrasion without delaying healing?
    Annals of emergency medicine, 2003, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Corneal Injuries; Diclofenac; Double-Blind Method; Drug Combinations; Emergency Medicine; Evidence-Based Medicine; Eye Foreign Bodies; Eye Injuries; Follow-Up Studies; Gentamicins; Humans; Indomethacin; Ketorolac; Middle Aged; Multicenter Studies as Topic; Ophthalmic Solutions; Pain; Pain Measurement; Pain Threshold; Placebos; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome; Wound Healing

2003
Nonsteroidal anti-inflammatory drugs (NSAIDs) in the newborn - which ones?
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2009, Volume: 22 Suppl 3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Hemorrhage; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Ketorolac

2009
Non-steroidal anti-inflammatory agents for treating cystoid macular oedema following cataract surgery.
    The Cochrane database of systematic reviews, 2012, Feb-15, Issue:2

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Chronic Disease; Fenoprofen; Humans; Indomethacin; Ketorolac; Macular Edema; Randomized Controlled Trials as Topic

2012
Role of indomethacin in acute pain and inflammation management: a review of the literature.
    Postgraduate medicine, 2014, Volume: 126, Issue:4

    Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Humans; Indomethacin; Inflammation; Ketorolac; Naproxen; Oxycodone; Piroxicam; Tramadol; Treatment Outcome

2014
Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions.
    The Cochrane database of systematic reviews, 2017, 05-18, Volume: 5

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Corneal Injuries; Diclofenac; Flurbiprofen; Humans; Indomethacin; Ketorolac; Pain Measurement; Randomized Controlled Trials as Topic; Wound Healing

2017
Comparison of different nonsteroidal anti-inflammatory drugs for cesarean section: a systematic review and network meta-analysis.
    Korean journal of anesthesiology, 2023, Volume: 76, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cesarean Section; Diclofenac; Female; Humans; Indomethacin; Ketorolac; Network Meta-Analysis; Pain; Pregnancy

2023

Trials

8 trial(s) available for ketorolac and indomethacin

ArticleYear
Ketorolac and indomethacin are equally efficacious for the relief of minor postoperative pain.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:12

    Topics: Administration, Rectal; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Fentanyl; Humans; Indomethacin; Injections, Intramuscular; Ketorolac; Middle Aged; Pain Measurement; Pain, Postoperative; Placebos; Prospective Studies; Suppositories; Time Factors; Tolmetin

1993
Indomethacin and ketorolac given preoperatively are equally effective in reducing early postoperative pain after laparoscopic cholecystectomy.
    Canadian journal of surgery. Journal canadien de chirurgie, 1996, Volume: 39, Issue:1

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic; Cholelithiasis; Double-Blind Method; Female; Humans; Indomethacin; Ketorolac; Male; Pain, Postoperative; Preoperative Care; Prospective Studies; Tolmetin

1996
A comparison of intramuscular ketorolac with indomethacin suppositories in the treatment of pain after oral surgery.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:6

    Topics: Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethacin; Injections, Intramuscular; Ketorolac; Male; Nausea; Pain Measurement; Pain, Postoperative; Single-Blind Method; Suppositories; Tolmetin; Tooth Extraction; Vomiting

1996
A comparison of the efficacy of ketorolac and indomethacin for postoperative analgesia following laparoscopic surgery in day patients.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:2

    Topics: Acute Kidney Injury; Administration, Rectal; Adolescent; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Indomethacin; Injections, Intramuscular; Ketorolac; Laparoscopy; Middle Aged; Pain Measurement; Pain, Postoperative; Placebos; Suppositories; Tolmetin

1996
Efficacy of topical nonsteroidal drops as pain relief after excimer laser photorefractive keratectomy.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 1998, Volume: 14, Issue:2 Suppl

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism; Cornea; Double-Blind Method; Humans; Indomethacin; Ketorolac; Lasers, Excimer; Myopia; Ophthalmic Solutions; Pain Measurement; Pain, Postoperative; Photorefractive Keratectomy; Safety; Tolmetin

1998
The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects.
    Eye (London, England), 2000, Volume: 14 ( Pt 2)

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diclofenac; Double-Blind Method; Epithelium, Corneal; Female; Flurbiprofen; Humans; Indomethacin; Ketorolac; Male; Middle Aged; Paresthesia; Procaine

2000
Resistive index in patients with renal colic: differences after medical treatment with indomethacin and ketorolac.
    La Radiologia medica, 2003, Volume: 106, Issue:4

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Colic; Humans; Indomethacin; Ketorolac; Kidney Diseases; Ureteral Obstruction; Vascular Resistance

2003
Carbon dioxide-mediated vasomotion of extra-cranial cerebral arteries in humans: a role for prostaglandins?
    The Journal of physiology, 2016, 06-15, Volume: 594, Issue:12

    Topics: Adolescent; Adult; Carbon Dioxide; Carotid Artery, Internal; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Humans; Hypercapnia; Hypocapnia; Indomethacin; Ketorolac; Male; Middle Cerebral Artery; Naproxen; Prostaglandins; Single-Blind Method; Ultrasonography, Doppler, Duplex; Vasoconstriction; Vasodilation; Young Adult

2016

Other Studies

39 other study(ies) available for ketorolac and indomethacin

ArticleYear
Antinociceptive (aminoalkyl)indoles.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Analgesia; Analgesics; Animals; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Indoles; Magnetic Resonance Spectroscopy; Male; Methylation; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Vas Deferens

1991
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-ca rboxyl ic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Acetates; Analgesia; Animals; Aspirin; Benzoquinones; Carboxylic Acids; Carrageenan; Chemical Phenomena; Chemistry; Edema; Inflammation; Mice; Molecular Structure; Pain Measurement; Phenylbutazone; Pyrroles; Quinones; Rats

1989
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Synthesis and hypolipidemic and antiplatelet activities of alpha-asarone isomers in humans (in vitro), mice (in vivo), and rats (in vivo).
    Journal of medicinal chemistry, 2000, Oct-05, Volume: 43, Issue:20

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Fibrinolytic Agents; Humans; Hypolipidemic Agents; In Vitro Techniques; Lung; Male; Mice; Platelet Aggregation; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship; Thromboembolism

2000
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism

2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Lipophilicity of acidic compounds: impact of ion pair partitioning on drug design.
    Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12

    Topics: Acids; Albumins; Drug Design; Humans; Hydrogen-Ion Concentration; Lipids; Molecular Structure; Pharmaceutical Preparations; Protein Binding

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Benzoxazoles; Carrageenan; Cell Line, Tumor; Chlorocebus aethiops; Dimerization; Drug Design; Edema; Epithelial Cells; Hindlimb; Humans; Kidney; Macrophages; Mice; Molecular Docking Simulation; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Structure-Activity Relationship; Swine; Vero Cells

2015
Comparative effects of four prostaglandin synthesis inhibitors on the obstructed kidney in the dog.
    The Journal of urology, 1986, Volume: 135, Issue:5

    Topics: Animals; Blood Pressure; Dogs; Female; Ibuprofen; Indomethacin; Ketorolac; Kidney Pelvis; Naproxen; Pressure; Prostaglandin Antagonists; Tolmetin; Ureteral Obstruction

1986
Comparative studies of antiplatelet activity of nonsteroidal antiinflammatory drugs and new pyrazine CH- and NH-acids.
    Life sciences, 1995, Volume: 56, Issue:9

    Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Collagen; Epinephrine; Fibrinolytic Agents; Humans; Indomethacin; Ketorolac; Male; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Embolism; Pyrazines; Tolmetin

1995
Previous administration of indomethacin or naloxone did not influence ketorolac antinociception in mice.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:4

    Topics: Animals; Cecum; Cerebral Ventricles; Indomethacin; Injections, Intraperitoneal; Ketorolac; Mice; Naloxone; Time Factors; Tolmetin

1993
Differential effect of indomethacin and ketorolac on postoperative ileus in rats.
    European journal of pharmacology, 1998, Feb-26, Volume: 344, Issue:1

    Topics: Animals; Disease Models, Animal; Indomethacin; Intestinal Obstruction; Ketorolac; Nitric Oxide; Nitroarginine; Postoperative Complications; Prostaglandin Antagonists; Rats; Tolmetin

1998
Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells.
    Blood, 1998, Aug-15, Volume: 92, Issue:4

    Topics: Aged; Amino Acid Chloromethyl Ketones; Annexins; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; B-Lymphocytes; Cell Survival; Cyclooxygenase Inhibitors; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Activation; Female; Humans; Indomethacin; Ketorolac; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Proteins; Nitrobenzenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Salicylates; Salicylic Acid; Sulfonamides; Tolmetin; Tumor Cells, Cultured

1998
Role of COX-2 inhibition on the formation and healing of gastric ulcers induced by indomethacin in the rat.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Indomethacin; Isoenzymes; Ketorolac; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides; Time Factors; Wound Healing

1999
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
    Medicine and health, Rhode Island, 2001, Volume: 84, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Etodolac; Humans; Ibuprofen; Indomethacin; Ketorolac; Lactones; Nabumetone; Naproxen; Pain, Postoperative; Piroxicam; Pyrazoles; Sulfonamides; Sulfones; Time Factors

2001
Effects of nonsteroidal anti-inflammatory drugs on transforming growth factor-beta expression and bioactivity in rat osteoblast-enriched culture.
    The Kaohsiung journal of medical sciences, 2003, Volume: 19, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Indomethacin; Ketorolac; Osteoblasts; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta

2003
Cyclooxygenase 2 (COX-2) inhibition increases the inflammatory response in the brain during systemic immune stimuli.
    Journal of neurochemistry, 2005, Volume: 95, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression; In Situ Hybridization; Indomethacin; Inflammation; Intramolecular Oxidoreductases; Ketorolac; Lipopolysaccharides; Male; Mice; Nitrobenzenes; Plasmids; Prostaglandin-E Synthases; Pyrazoles; Sulfonamides

2005
Cyclooxygenase-2 inhibition increases gastric tone and delays gastric emptying in rats.
    Neurogastroenterology and motility, 2007, Volume: 19, Issue:3

    Topics: Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Gastric Emptying; Gastric Mucosa; Indomethacin; Isoxazoles; Ketorolac; Lactones; Male; Muscle, Smooth; Pyrazoles; Rats; Rats, Wistar; Stomach; Sulfonamides; Sulfones

2007
Ketorolac effectively inhibits ureteral contractility in vitro.
    Journal of endourology, 2008, Volume: 22, Issue:4

    Topics: Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Ketorolac; Muscle Contraction; Swine; Ureter

2008
Anti-inflammatory drugs suppress proliferation and induce apoptosis through altering expressions of cell cycle regulators and pro-apoptotic factors in cultured human osteoblasts.
    Toxicology, 2009, Apr-28, Volume: 258, Issue:2-3

    Topics: Annexin A5; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Celecoxib; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Dexamethasone; Diclofenac; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Indomethacin; Ketorolac; L-Lactate Dehydrogenase; Osteoblasts; Piroxicam; Propidium; Pyrazoles; RNA, Messenger; Sulfonamides; Thymidine

2009
Triptan therapy in migraine.
    The New England journal of medicine, 2010, 09-30, Volume: 363, Issue:14

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Indomethacin; Injections, Intravenous; Ketorolac; Migraine Disorders; Sumatriptan; United States; Vasoconstrictor Agents

2010
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts

2012
Locally Delivered Nonsteroidal Antiinflammatory Drug: A Potential Option for Heterotopic Ossification Prevention.
    Clinical and translational science, 2015, Volume: 8, Issue:5

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA Replication; Female; Humans; Ibuprofen; Indomethacin; Ketorolac; Male; Ossification, Heterotopic; Osteoblasts; Rats; Skin; Time Factors; Wound Healing; Wounds and Injuries

2015
Antihyperalgesic Effects of Indomethacin, Ketorolac, and Metamizole in Rats: Effects of Metformin.
    Drug development research, 2017, Volume: 78, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dipyrone; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Hyperalgesia; Indomethacin; Ketorolac; Male; Metformin; Rats; Rats, Sprague-Dawley; Treatment Outcome

2017
Risk of acute myocardial infarction during use of individual NSAIDs: A nested case-control study from the SOS project.
    PloS one, 2018, Volume: 13, Issue:11

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Diclofenac; Etoricoxib; Female; Humans; Indomethacin; Ketorolac; Lactones; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Risk Factors; Sulfones

2018
The effect of non-steroidal anti-inflammatory drugs on osteosarcoma cells.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Indomethacin; Ketorolac; Osteosarcoma; Poly (ADP-Ribose) Polymerase-1; Proto-Oncogene Proteins c-bcl-2; Rats; Survivin

2019
Isobolographic analysis of antinociceptive effect of ketorolac, indomethacin, and paracetamol after simultaneous peripheral local and systemic administration.
    Behavioural pharmacology, 2022, 02-01, Volume: 33, Issue:1

    Topics: Acetaminophen; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Synergism; Drug Therapy, Combination; Indomethacin; Inflammation; Ketorolac; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Treatment Outcome

2022