ketorolac and dinoprostone

ketorolac has been researched along with dinoprostone in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (17.65)	18.2507
2000's	19 (55.88)	29.6817
2010's	8 (23.53)	24.3611
2020's	1 (2.94)	2.80

Authors

Authors	Studies
Bellman, K; Knegtel, RM; Settimo, L	1
Butelman, ER; Gatch, MB; Negus, SS; Woods, JH	1
Chang, JK; Ho, ML; Wang, GJ	1
Hayashi, S; McDonnell, PJ; Phillips, AF; Seitz, B; Wee, WR	1
Isakson, PC; Portanova, J; Seibert, K; Shaffer, A; Zhang, Y	1
Chang, JK; Chuang, LY; Ho, ML; Hsu, HK; Wang, GJ	1
Fernández, AG; Godessart, N; Palacios, JM; Salcedo, C	1
Rivest, S; Zhang, J	1
Avis, IM; Cavanaugh, PF; Chen, Z; Hong, SH; Loukinova, E; Mulshine, JL; Ondrey, FG; Van Waes, C	1
Junger, H; Sorkin, LS	1
Gupta, AK; Madan, S; Maitra, A; Majumdar, DK	1
Brandt, MR; Furness, MS; Mello, NK; Negus, SS; Rice, KC	1
Felder, RB; Francis, J; Wei, SG; Zhang, ZH	1
Debelak, JP; Jones, AE; Kline, JA; Thornton, LR; Watts, JA; Younger, JG	1
Brahim, JS; Dionne, RA; Gordon, SM; Kent, A; Rowan, J	1
Eisenach, JC; Ma, W	1
Blais, V; Rivest, S; Turrin, NP	1
Buvanendran, A; Kroin, JS; Saha, C; Tuman, KJ; Watts, DE	1
Al-Ghawas, M; Alkhiary, YM; Cullinane, DM; Einhorn, TA; Fitch, JL; Gerstenfeld, LC; Krall, EA; Thiede, MA; Webb, EG	1
Majumdar, DK; Malhotra, M	1
Ernest, P; Gayton, J; Lehmann, R; Raizman, M; Walters, T	1
Bucci, FA; Waterbury, LD	3
Gayton, J	1
Barañano, DE; Durairaj, C; Edelhauser, HF; Handa, JT; Kim, SJ; Kompella, UB	1
Awh, CC; Busbee, BG; Cleary, TS; Daniel, P; Heier, JS; Stoller, GL; Waterbury, LD	1
Barnett, JM; Kim, SJ; Penn, JS; Toma, HS	1
Attar, M; Borbridge, L; Galindo, D; Hollander, DA; Nguyen, C; Patel, M; Schiffman, RM; Villanueva, L; Waterbury, LD	1
Cairns, BE; Dong, XD; Svensson, P; Wong, H	1
Acar, DE; Acar, M; Acar, U; Erikci, A; Ornek, F; Ozdemir, O; Tanriverdi, C	1
Aranda, JV; Beharry, KD; Cai, CL; Lazzaro, D; Salomone, F; Valencia, AM; Valencia, GB	1
Borish, L; Pal, K; Payne, SC; Ramsden, M; Shim, YM; Steinke, JW	1
Baumann, JR; Bozynski, CC; Cook, JL; Sherman, SL; Stoker, AM	1

Trials

5 trial(s) available for ketorolac and dinoprostone

Article	Year
Dexamethasone suppresses peripheral prostanoid levels without analgesia in a clinical model of acute inflammation. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2003, Volume: 61, Issue:9 Topics: Adult; Analgesia; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Dinoprostone; Double-Blind Method; Female; Humans; Ketorolac; Male; Mandible; Molar, Third; Pain Measurement; Pain, Postoperative; Postoperative Care; Preoperative Care; Prospective Studies; Thromboxane B2; Tooth Extraction; Tooth, Impacted	2003
In vivo pharmacokinetics and in vitro pharmacodynamics of nepafenac, amfenac, ketorolac, and bromfenac. Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Area Under Curve; Benzeneacetamides; Benzophenones; Biological Availability; Bromobenzenes; Cataract Extraction; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Double-Blind Method; Female; Humans; Ketorolac; Male; Middle Aged; Phenylacetates	2007
Comparison of ketorolac 0.4% and bromfenac 0.09% at trough dosing: aqueous drug absorption and prostaglandin E2 levels. Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:9 Topics: Absorption; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Benzophenones; Bromobenzenes; Chromatography, High Pressure Liquid; Dinoprostone; Double-Blind Method; Female; Humans; Immunoenzyme Techniques; Ketorolac; Male; Mass Spectrometry; Middle Aged; Ophthalmic Solutions; Phacoemulsification	2008
Vitreous nonsteroidal antiinflammatory drug concentrations and prostaglandin E2 levels in vitrectomy patients treated with ketorolac 0.4%, bromfenac 0.09%, and nepafenac 0.1%. Retina (Philadelphia, Pa.), 2009, Volume: 29, Issue:9 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Benzophenones; Biological Availability; Bromobenzenes; Chromatography, High Pressure Liquid; Dinoprostone; Female; Humans; Ketorolac; Male; Mass Spectrometry; Middle Aged; Ophthalmic Solutions; Phenylacetates; Retinal Diseases; Tissue Distribution; Vitrectomy; Vitreous Body	2009
Prostaglandin E2 inhibition of ketorolac 0.45%, bromfenac 0.09%, and nepafenac 0.1% in patients undergoing phacoemulsification. Advances in therapy, 2011, Volume: 28, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Benzophenones; Bromobenzenes; Dinoprostone; Double-Blind Method; Female; Humans; Ketorolac; Male; Middle Aged; Ophthalmic Solutions; Phacoemulsification; Phenylacetates	2011

Other Studies

29 other study(ies) available for ketorolac and dinoprostone

Article	Year
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Effects of morphine and ketorolac on thermal allodynia induced by prostaglandin E2 and bradykinin in rhesus monkeys. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:2 Topics: Analgesics, Non-Narcotic; Animals; Azocines; Bradykinin; Dinoprostone; Female; Ketorolac; Macaca mulatta; Male; Morphine; Pain; Temperature; Tolmetin	1995
Antiinflammatory drug effects on bone repair and remodeling in rabbits. Clinical orthopaedics and related research, 1995, Issue:313 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Bone Matrix; Bone Regeneration; Bone Remodeling; Bone Transplantation; Dinoprostone; Ionophores; Ketorolac; Male; Methylprednisolone; Rabbits; Tolmetin; Ulna	1995
Effect of diclofenac, ketorolac, and fluorometholone on arachidonic acid metabolites following excimer laser corneal surgery. Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:12 Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Chemotaxis, Leukocyte; Cornea; Diclofenac; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Fluorometholone; Ketorolac; Lasers, Excimer; Leukotriene B4; Neutrophils; Ophthalmic Solutions; Photorefractive Keratectomy; Rabbits; Tolmetin	1996
Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:3 Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Hyperalgesia; Inflammation; Ketorolac; Male; Rats; Rats, Sprague-Dawley; Tolmetin	1997
Characteristics of primary osteoblast culture derived from rat fetal calvaria. The Kaohsiung journal of medical sciences, 1999, Volume: 15, Issue:5 Topics: Alkaline Phosphatase; Animals; Cells, Cultured; Dinoprostone; Female; Fetus; Ketorolac; Osteoblasts; Pregnancy; Rats; Rats, Sprague-Dawley; Skull; Tolmetin	1999
Role of COX-2 inhibition on the formation and healing of gastric ulcers induced by indomethacin in the rat. Advances in experimental medicine and biology, 1999, Volume: 469 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Indomethacin; Isoenzymes; Ketorolac; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides; Time Factors; Wound Healing	1999
A functional analysis of EP4 receptor-expressing neurons in mediating the action of prostaglandin E2 within specific nuclei of the brain in response to circulating interleukin-1beta. Journal of neurochemistry, 2000, Volume: 74, Issue:5 Topics: Animals; Brain; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression; Genes, Immediate-Early; Hypothalamo-Hypophyseal System; Immune Sera; Injections, Intraventricular; Interleukin-1; Ketorolac; Male; Medulla Oblongata; Neurons; Phenylethanolamine N-Methyltransferase; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Transcription, Genetic	2000
Cyclooxygenase regulates human oropharyngeal carcinomas via the proinflammatory cytokine IL-6: a general role for inflammation? FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:11 Topics: Animals; Antibodies; Arachidonic Acid; Cell Division; Clinical Trials, Phase II as Topic; Culture Media, Conditioned; Cyclooxygenase Inhibitors; Dinoprostone; DNA-Binding Proteins; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Inflammation; Interleukin-1; Interleukin-6; Interleukin-8; Isoenzymes; Ketorolac; Mice; Mice, Inbred BALB C; Models, Biological; Oropharyngeal Neoplasms; Paracrine Communication; Prostaglandin-Endoperoxide Synthases; Receptors, Interleukin-6; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured	2000
Isoprostanes induce plasma extravasation in rat skin. Prostaglandins & other lipid mediators, 2000, Volume: 62, Issue:4 Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; F2-Isoprostanes; Ibuprofen; Inflammation; Injections, Subcutaneous; Isoprostanes; Ketorolac; Male; Rats	2000
Ketorolac entrapped in polymeric micelles: preparation, characterisation and ocular anti-inflammatory studies. International journal of pharmaceutics, 2000, Nov-19, Volume: 209, Issue:1-2 Topics: Acrylamides; Acrylates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Excipients; Eye Diseases; In Vitro Techniques; Inflammation; Ketorolac; Magnetic Resonance Spectroscopy; Micelles; Microscopy, Electron; Ophthalmic Solutions; Particle Size; Polymers; Pyrrolidinones; Rabbits; Solubility; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction	2000
Antinociceptive effects of delta-opioid agonists in Rhesus monkeys: effects on chemically induced thermal hypersensitivity. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3 Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Freund's Adjuvant; Hyperalgesia; Ketorolac; Macaca mulatta; Male; Morphine; Pain; Pain Measurement; Piperazines; Receptors, Opioid, delta	2001
Cardiovascular and renal sympathetic activation by blood-borne TNF-alpha in rat: the role of central prostaglandins. American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:4 Topics: Animals; Blood Pressure; Cardiovascular System; Dinoprostone; Heart Rate; Ketorolac; Kidney; Male; Medulla Oblongata; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tumor Necrosis Factor-alpha; Vagotomy	2003
Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 284, Issue:6 Topics: Angiography; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Disease Models, Animal; Extravascular Lung Water; Hypotension; Isoenzymes; Ketorolac; Membrane Proteins; Microspheres; Pleural Effusion; Polystyrenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pulmonary Circulation; Pulmonary Embolism; Rats; Rats, Sprague-Dawley; Respiratory Dead Space; Survival Rate; Thromboxane B2; Thromboxane-A Synthase	2003
Four PGE2 EP receptors are up-regulated in injured nerve following partial sciatic nerve ligation. Experimental neurology, 2003, Volume: 183, Issue:2 Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Immunohistochemistry; Ketorolac; Ligation; Macrophages; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sciatic Nerve; Sciatic Neuropathy; Up-Regulation	2003
Cyclooxygenase 2 (COX-2) inhibition increases the inflammatory response in the brain during systemic immune stimuli. Journal of neurochemistry, 2005, Volume: 95, Issue:6 Topics: Animals; Blood-Brain Barrier; Brain; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression; In Situ Hybridization; Indomethacin; Inflammation; Intramolecular Oxidoreductases; Ketorolac; Lipopolysaccharides; Male; Mice; Nitrobenzenes; Plasmids; Prostaglandin-E Synthases; Pyrazoles; Sulfonamides	2005
Upregulation of cerebrospinal fluid and peripheral prostaglandin E2 in a rat postoperative pain model. Anesthesia and analgesia, 2006, Volume: 103, Issue:2 Topics: Animals; Bupivacaine; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Isoflurane; Ketorolac; Laparotomy; Male; Motor Activity; Pain, Postoperative; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Thoracic Surgical Procedures; Up-Regulation	2006
Selective and nonselective cyclooxygenase-2 inhibitors and experimental fracture-healing. Reversibility of effects after short-term treatment. The Journal of bone and joint surgery. American volume, 2007, Volume: 89, Issue:1 Topics: Animals; Biomechanical Phenomena; Bony Callus; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Fracture Fixation, Intramedullary; Fracture Healing; Fractures, Bone; Fractures, Ununited; Isoxazoles; Ketorolac; Male; Rats; Rats, Sprague-Dawley; Sulfonamides	2007
Aqueous, oil, and ointment formulations of ketorolac: efficacy against prostaglandin E2-induced ocular inflammation and safety: a technical note. AAPS PharmSciTech, 2006, Volume: 7, Issue:4 Topics: Administration, Topical; Animals; Dinoprostone; Drug Compounding; Excipients; Female; Ketorolac; Male; Oils; Ointments; Osteitis; Rabbits; Treatment Outcome; Water	2006
Re: Pharmacokinetics and pharmacodynamics of nepafenac, amfenac, ketorolac, and bromfenac. Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Area Under Curve; Benzeneacetamides; Benzophenones; Biological Availability; Bromobenzenes; Cataract Extraction; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Ketorolac; Phenylacetates	2008
Concentration and dosing of ketorolac versus bromfenac. Journal of cataract and refractive surgery, 2009, Volume: 35, Issue:7 Topics: Absorption; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Benzophenones; Bromobenzenes; Chromatography, High Pressure Liquid; Dinoprostone; Humans; Immunoenzyme Techniques; Ketorolac; Mass Spectrometry; Ophthalmic Solutions; Phacoemulsification	2009
Efficacy and pharmacokinetics of intravitreal non-steroidal anti-inflammatory drugs for intraocular inflammation. The British journal of ophthalmology, 2009, Volume: 93, Issue:10 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Injections; Ketorolac; Lipopolysaccharides; Male; Rabbits; Treatment Outcome; Uveitis; Vitreous Body	2009
Ketorolac inhibits choroidal neovascularization by suppression of retinal VEGF. Experimental eye research, 2010, Volume: 91, Issue:4 Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Choroidal Neovascularization; Dinoprostone; Disease Models, Animal; Fluorescein Angiography; Ketorolac; Male; Rats; Rats, Inbred BN; Retina; Vascular Endothelial Growth Factor A; Vitreous Body	2010
Ocular penetration and anti-inflammatory activity of ketorolac 0.45% and bromfenac 0.09% against lipopolysaccharide-induced inflammation. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2011, Volume: 27, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Benzophenones; Bromobenzenes; Dextrans; Dinoprostone; Endophthalmitis; Eye; Female; Fluorescein-5-isothiocyanate; Ketorolac; Lipopolysaccharides; Prostaglandin-Endoperoxide Synthases; Rabbits	2011
Intramuscular ketorolac inhibits activation of rat peripheral NMDA receptors. Journal of neurophysiology, 2012, Volume: 107, Issue:12 Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Excitatory Amino Acid Agonists; Female; Injections, Intramuscular; Ketorolac; Male; Naproxen; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Trigeminal Nerve	2012
Prostaglandin E Ocular immunology and inflammation, 2017, Volume: 25, Issue:3 Topics: Administration, Ophthalmic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Benzeneacetamides; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Ketorolac; Ophthalmic Solutions; Phenylacetates; Rabbits; Vitreous Body	2017
Human retinal endothelial cells and astrocytes cultured on 3-D scaffolds for ocular drug discovery and development. Prostaglandins & other lipid mediators, 2018, Volume: 134 Topics: Astrocytes; Biomimetics; Coculture Techniques; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Dinoprost; Dinoprostone; Drug Discovery; Drug Interactions; Endothelial Cells; Humans; Ibuprofen; Ketorolac; Retina; Thromboxane B2	2018
Suppression of aspirin-mediated eosinophil activation by prostaglandin E Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2019, Volume: 123, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Cysteine; Dinoprostone; Drug Hypersensitivity; Eosinophils; Humans; Ketorolac; Leukotriene B4; Leukotrienes; Lysine; Sodium Salicylate	2019
An Injectable Containing Morphine, Ropivacaine, Epinephrine, and Ketorolac Is Not Cytotoxic to Articular Cartilage Explants From Degenerative Knees. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2022, Volume: 38, Issue:6 Topics: Anesthetics, Local; Cartilage, Articular; Dinoprostone; Epinephrine; Humans; Injections, Intra-Articular; Ketorolac; Matrix Metalloproteinase 7; Matrix Metalloproteinase 8; Morphine; Pain, Postoperative; Ropivacaine	2022