Page last updated: 2024-09-03

ketoprofen glucuronide and naproxen

ketoprofen glucuronide has been researched along with naproxen in 3 studies

Compound Research Comparison

Studies
(ketoprofen glucuronide)
Trials
(ketoprofen glucuronide)
Recent Studies (post-2010)
(ketoprofen glucuronide)
Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010) (naproxen)
17134,5511,0571,429

Protein Interaction Comparison

ProteinTaxonomyketoprofen glucuronide (IC50)naproxen (IC50)
Prostaglandin G/H synthase 1Ovis aries (sheep)1.1642
Hormone-sensitive lipaseRattus norvegicus (Norway rat)1.2
Prostaglandin G/H synthase 1Homo sapiens (human)4.0203
Prostaglandin G/H synthase 2Homo sapiens (human)3.8725
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.06
Aldo-keto reductase family 1 member C3Homo sapiens (human)0.5867
Aldo-keto reductase family 1 member C2 Homo sapiens (human)1.26
Prostaglandin G/H synthase 2Ovis aries (sheep)3.36
Solute carrier family 22 member 6Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.06

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Hansen, SH; Mortensen, RW; Sidelmann, UG; Tjørnelund, J1
Iwaki, M; Kawase, A; Kobayashi, Y; Ogiso, T; Shimada, H; Tanahashi, S1

Other Studies

3 other study(ies) available for ketoprofen glucuronide and naproxen

ArticleYear
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
Stereospecific pH-dependent degradation kinetics of R- and S-naproxen-beta-l-O-acyl-glucuronide.
    Chirality, 2002, May-05, Volume: 14, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Female; Glucuronides; Hydrogen-Ion Concentration; In Vitro Techniques; Ketoprofen; Kinetics; Microsomes, Liver; Naproxen; Stereoisomerism; Swine

2002
Correlation between glucuronidation and covalent adducts formation with proteins of nonsteroidal anti-inflammatory drugs.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Jan-15, Volume: 112

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Flurbiprofen; Glucuronides; Ibuprofen; Ketoprofen; Male; Microsomes, Liver; Naproxen; Propionates; Protein Binding; Rats, Wistar

2018