ketoprofen has been researched along with warfarin in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.35) | 18.7374 |
| 1990's | 3 (6.52) | 18.2507 |
| 2000's | 23 (50.00) | 29.6817 |
| 2010's | 18 (39.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Faller, B; Wohnsland, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Caron, G; Ermondi, G | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Botta, M; Dreassi, E; Falchi, F; Maga, G; Santucci, A; Schenone, S; Zizzari, AT | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Blair, A; Boyd, M; Chalmers, AJ; Malviya, G; Pimlott, SL; Sutherland, A; Zmuda, F | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Hage, DS; Noctor, TA; Wainer, IW | 1 |
| Bochner, F; Hayball, PJ; Nation, RL | 1 |
| Flessner, MF; Knight, H | 1 |
| Wilson, FS | 1 |
| Mieszczak, C; Winther, K | 1 |
| Owens, PK; Svensson, LA | 1 |
| Asakawa, N; Ishihama, Y; Miwa, T | 1 |
| Chen, XM; Ni, JY; Wang, HL; Yao, PJ; Zhang, Q; Zhang, ZZ; Zou, HF | 1 |
| Tanaka, Y | 1 |
| Lei, ZD; Ni, JY; Wu, RA; Ye, ML; Zou, HF | 1 |
| Andrisano, V; Bertucci, C; Cavrini, V; Gotti, R; Pomponio, R | 1 |
| Anraku, M; Iwao, Y; Kawai, K; Kragh-Hansen, U; Maruyama, T; Otagiri, M; Yamasaki, K | 1 |
| Balchen, M; Gjelstad, A; Pedersen-Bjergaard, S; Rasmussen, KE | 1 |
| Izumi, M; Maruyama, T; Mera, K; Nagai, R; Otagiri, M; Takeo, K | 1 |
| Correa-Basurto, J; Deeb, O; Garduño-Juárez, R; Gómez-Castro, C; Rosales-Hernández, MC | 1 |
| Baraka-Vidot, J; Bourdon, E; Guerin-Dubourg, A; Rondeau, P | 1 |
| Abdulmalik, A; Daisuke, I; Fumitoshi, H; Hibah, A; Kaneto, U; Makoto, A; Masaki, O; Zainy, BM | 1 |
| Bi, YA; Callegari, E; Lin, J; Mathialagan, S; Rodrigues, AD; Tylaska, L; Varma, MVS | 1 |
2 review(s) available for ketoprofen and warfarin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Method development of enantiomer separations by affinity capillary electrophoresis, cyclodextrin electrokinetic chromatography and capillary electrophoresis-mass spectrometry.
Topics: Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Electrophoresis, Capillary; Ibuprofen; Ketoprofen; Mass Spectrometry; Static Electricity; Stereoisomerism; Vanilmandelic Acid; Warfarin | 2002 |
1 trial(s) available for ketoprofen and warfarin
| Article | Year |
|---|---|
Lack of interaction of ketoprofen with warfarin.
Topics: Adult; Double-Blind Method; Drug Interactions; Humans; Ketoprofen; Male; Middle Aged; Partial Thromboplastin Time; Platelet Aggregation; Platelet Count; Prothrombin Time; Thrombin Time; Warfarin | 1993 |
43 other study(ies) available for ketoprofen and warfarin
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data.
Topics: Humans; Lipids; Membranes, Artificial; Permeability; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrazoles; Pyrimidines | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Synthesis and Evaluation of a Radioiodinated Tracer with Specificity for Poly(ADP-ribose) Polymerase-1 (PARP-1) in Vivo.
Topics: Animals; Cell Line, Tumor; Enzyme Inhibitors; Glioblastoma; Humans; Iodine Radioisotopes; Mice; Mice, Nude; Phthalazines; Piperazines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2015 |
Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase.
Topics: Allosteric Site; Binding, Competitive; Caprylates; Chromatography, High Pressure Liquid; Humans; Ketoprofen; Oxazepam; Pharmaceutical Preparations; Phenylbutazone; Serum Albumin; Stereoisomerism; Suprofen; Tolbutamide; Warfarin | 1992 |
Stereoselective interactions of ketoprofen glucuronides with human plasma protein and serum albumin.
Topics: Adult; Blood Proteins; Diazepam; Esters; Female; Humans; Hydrolysis; Ketoprofen; Male; Middle Aged; Protein Binding; Serum Albumin; Warfarin | 1992 |
Prolongation of prothrombin time and severe gastrointestinal bleeding associated with combined use of warfarin and ketoprofen.
Topics: Drug Interactions; Gastrointestinal Hemorrhage; Humans; Ketoprofen; Male; Middle Aged; Phenylpropionates; Prothrombin Time; Warfarin | 1988 |
Bleeding in a patient receiving warfarin and ketoprofen.
Topics: Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Ketoprofen; Phenylpropionates; Warfarin | 1988 |
Enantioselective supercritical fluid chromatography using ristocetin A chiral stationary phases.
Topics: 2,4-Dichlorophenoxyacetic Acid; Anesthetics, Local; Anti-Bacterial Agents; Bupivacaine; Chromatography, Liquid; Coumarins; Evaluation Studies as Topic; Ketoprofen; Metoprolol; Propranolol; Reagent Kits, Diagnostic; Ristocetin; Stereoisomerism; Thalidomide; Warfarin | 2000 |
Drug-plasma protein binding assay by electrokinetic chromatography-frontal analysis.
Topics: beta-Cyclodextrins; Blood Proteins; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Diclofenac; Electrophoresis, Capillary; Humans; Ketoprofen; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Serum Albumin; Sulfathiazole; Sulfathiazoles; Warfarin | 2002 |
[The effect of temperature on the enantiomeric resolutions on albumin and beta-cyclodextrin chiral stationary phases].
Topics: beta-Cyclodextrins; Chromatography; Cyclodextrins; Ketoprofen; Serum Albumin; Serum Albumin, Bovine; Stereoisomerism; Temperature; Tryptophan; Warfarin | 2001 |
[Chiral separation by capillary electrochromatography on stationary phase adsorbed with protein].
Topics: Acetonitriles; Adsorption; Antiporters; Chromatography; Electrophoresis, Capillary; Ketoprofen; Proteins; Serum Albumin, Bovine; Stereoisomerism; Warfarin | 2001 |
Study of donepezil binding to serum albumin by capillary electrophoresis and circular dichroism.
Topics: Bilirubin; Binding Sites; Bromphenol Blue; Circular Dichroism; Donepezil; Electrophoresis, Capillary; Humans; Indans; Ketoprofen; Piperidines; Protein Binding; Reproducibility of Results; Serum Albumin; Time Factors; Warfarin | 2003 |
Oxidation of Arg-410 promotes the elimination of human serum albumin.
Topics: Amino Acid Sequence; Animals; Arginine; Half-Life; Humans; Hydrophobic and Hydrophilic Interactions; Ketoprofen; Liver; Male; Mice; Oxidation-Reduction; Point Mutation; Protein Conformation; Serum Albumin; Warfarin | 2006 |
Electrokinetic migration of acidic drugs across a supported liquid membrane.
Topics: Acids; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Flurbiprofen; Gemfibrozil; Heptanol; Hydrogen-Ion Concentration; Ketoprofen; Membranes, Artificial; Naproxen; Pharmaceutical Preparations; Probenecid; Reproducibility of Results; Warfarin | 2007 |
Effect of reactive-aldehydes on the modification and dysfunction of human serum albumin.
Topics: Aldehydes; Arginine; Chemical Phenomena; Glycation End Products, Advanced; Humans; Ketoprofen; Protein Binding; Serum Albumin; Warfarin | 2010 |
Exploration of human serum albumin binding sites by docking and molecular dynamics flexible ligand-protein interactions.
Topics: Binding Sites; Humans; In Vitro Techniques; Ketoprofen; Ligands; Models, Molecular; Protein Conformation; Protein Interaction Domains and Motifs; Quantitative Structure-Activity Relationship; Serum Albumin; Thermodynamics; Warfarin | 2010 |
Impaired drug-binding capacities of in vitro and in vivo glycated albumin.
Topics: Adult; Female; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Ketoprofen; Male; Middle Aged; Protein Binding; Serum Albumin; Warfarin | 2012 |
Preparation of soluble stable C₆₀/human serum albumin nanoparticles via cyclodextrin complexation and their reactive oxygen production characteristics.
Topics: Amino Acids, Aromatic; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biphenyl Compounds; Cell Line, Tumor; Circular Dichroism; Cyclodextrins; Cytochromes c; Dermatitis, Phototoxic; Drug Stability; Free Radical Scavengers; Fullerenes; Humans; Ketoprofen; Ligands; Nanoparticles; Picrates; Reactive Oxygen Species; Serum Albumin; Solubility; Warfarin | 2013 |
Role of Hepatic Organic Anion Transporter 2 in the Pharmacokinetics of R- and S-Warfarin: In Vitro Studies and Mechanistic Evaluation.
Topics: Adult; Anticoagulants; Cyclosporine; Cytochrome P-450 CYP2C9; Drug Interactions; Female; HEK293 Cells; Hepatocytes; Humans; Ketoprofen; Liver; Liver-Specific Organic Anion Transporter 1; Middle Aged; Models, Biological; Organic Anion Transporters, Sodium-Independent; Solute Carrier Organic Anion Transporter Family Member 1B3; Stereoisomerism; Warfarin | 2018 |