ketoprofen and thromboxane b2

ketoprofen has been researched along with thromboxane b2 in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's17 (68.00)18.2507
2000's6 (24.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N1
Lloret, S; Moreno, JJ1
Bochner, F; Hayball, PJ; Nation, RL1
Barton, MH; Jackman, BR; Moore, JN; Morris, DD1
Landoni, MF; Lees, P3
Cunningham, FM; Landoni, MF; Lees, P2
Cipollone, F; Cuccurullo, F; di Giamberardino, M; Greco, A; Padovano, R; Panara, MR; Patrono, C; Rotondo, MT; Santini, G; Sciulli, MG1
Berti, F; Clavenna, G; Daffonchio, L; Omini, C; Rossoni, G1
Alfano, MC; Collins, JG; Jeffcoat, MK; Li, KL; Offenbacher, S; Smith, MA; Vogel, R1
Frölich, JC; Gutzki, FM; Stichtenoth, DO; Tsikas, D1
Ahern, MJ; Bochner, F; Hayball, PJ; Nation, RL; Sansom, LN; Smith, MD1
Carmody, JJ; Day, RO; Sheather-Reid, RB; Vial, JH; Walker, JS1
Clark, CK; Lake, P; Logdberg, L; MacKay, RJ1
Coghe, J; Deby-Dupont, G; Lekeux, P; Uystepruyst, C; Van de Weerdt, ML1
Anglarilli, G; Bidal, D; Comas, W; Landoni, MF; Lees, P; Mucci, N1
Arifah, AK; Frean, SP; Landoni, MF; Lees, P1
Cohen, AJ; Drejka, ML; Kalia, A; Kramer, N; Mihailescu, G; Rosenstein, ED; Van Solingen, RM1
Arifah, AK; Landoni, MF; Lees, P1
Lair, S; Livingston, A; Machin, KL; Tellier, LA1
Banting, A; Banting, S; Heinonen, K; Mustonen, K1
Borer, L; Jung, M; King, JN; Lees, P; Rudaz, C; Seewald, W1
Banting, A; Heinonen, M; Mustonen, K; Peltoniemi, OA; Raekallio, M; Vainio, O1

Trials

9 trial(s) available for ketoprofen and thromboxane b2

ArticleYear
Comparison of the effects of ketoprofen and flunixin meglumine on the in vitro response of equine peripheral blood monocytes to bacterial endotoxin.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1994, Volume: 58, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Clonixin; Endotoxins; Horse Diseases; Horses; Hydroxyeicosatetraenoic Acids; Ketoprofen; Monocytes; Thromboplastin; Thromboxane B2; Tumor Necrosis Factor-alpha

1994
Comparative pharmacodynamics of flunixin, ketoprofen and tolfenamic acid in calves.
    The Veterinary record, 1995, Oct-21, Volume: 137, Issue:17

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Clonixin; Cross-Over Studies; Dinoprostone; Edema; Glucuronidase; Ketoprofen; Neutrophils; ortho-Aminobenzoates; Superoxides; Thromboxane B2

1995
Pharmacokinetics and pharmacodynamics of ketoprofen in calves applying PK/PD modelling.
    Journal of veterinary pharmacology and therapeutics, 1995, Volume: 18, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Carrageenan; Cattle; Cattle Diseases; Cross-Over Studies; Diffusion Chambers, Culture; Dinoprostone; Dose-Response Relationship, Drug; Edema; Glucuronidase; Half-Life; Inflammation; Injections, Intravenous; Ketoprofen; Leukotriene B4; Male; Stereoisomerism; Thromboxane B2

1995
Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in the horse.
    Journal of veterinary pharmacology and therapeutics, 1996, Volume: 19, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Cross-Over Studies; Dinoprostone; Dose-Response Relationship, Drug; Edema; Extracellular Space; Glucuronidase; Horses; Injections, Intravenous; Ketoprofen; Male; Prostaglandin-Endoperoxide Synthases; Regression Analysis; Software; Stereoisomerism; Thromboxane B2

1996
Effects of ketoprofen and ibuprofen on platelet aggregation and prostanoid formation in man.
    European journal of clinical pharmacology, 1996, Volume: 51, Issue:3-4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Female; Humans; Ibuprofen; Ketoprofen; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Thromboxane B2

1996
The influence of renal function on the enantioselective pharmacokinetics and pharmacodynamics of ketoprofen in patients with rheumatoid arthritis.
    British journal of clinical pharmacology, 1993, Volume: 36, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Platelets; Blood Proteins; Female; Humans; Ketoprofen; Kidney; Kidney Function Tests; Male; Middle Aged; Molecular Conformation; Structure-Activity Relationship; Thromboxane B2

1993
Nonsteroidal antiinflammatory drugs in rheumatoid arthritis and osteoarthritis: support for the concept of "responders" and "nonresponders".
    Arthritis and rheumatism, 1997, Volume: 40, Issue:11

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Sedimentation; Cross-Over Studies; Double-Blind Method; Female; Humans; Ketoprofen; Lymphocyte Count; Male; Middle Aged; Osteoarthritis; Piroxicam; Receptors, Interleukin-2; Thromboxane B2; Tumor Necrosis Factor-alpha

1997
Ketoprofen and phenylbutazone attenuation of PAF-induced lung inflammation in calves.
    Veterinary journal (London, England : 1997), 1999, Volume: 157, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Dinoprostone; Ketoprofen; Leukotriene B4; Male; Phenylbutazone; Placebos; Platelet Activating Factor; Pneumonia; Respiration; Thromboxane B2

1999
Comparison of the effects of ketoprofen on platelet function in the presence and absence of aspirin.
    The American journal of medicine, 2001, Volume: 111, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Delayed-Action Preparations; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Humans; Ketoprofen; Male; Platelet Aggregation; Thromboxane B2

2001

Other Studies

16 other study(ies) available for ketoprofen and thromboxane b2

ArticleYear
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Aug-05, Volume: 100, Issue:16

    Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors

2003
In vitro and in vivo effects of the anti-inflammatory peptides, antiflammins.
    Biochemical pharmacology, 1992, Oct-06, Volume: 44, Issue:7

    Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Collagen; Dexamethasone; Ketoprofen; Male; Mice; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Phospholipases A; Phospholipases A2; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Thromboxane B2; Uteroglobin

1992
Enantioselective pharmacodynamics of the nonsteroidal antiinflammatory drug ketoprofen: in vitro inhibition of human platelet cyclooxygenase activity.
    Chirality, 1992, Volume: 4, Issue:8

    Topics: Blood Platelets; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Ketoprofen; Stereoisomerism; Thromboxane B2

1992
Comparison of the anti-inflammatory actions of flunixin and ketoprofen in horses applying PK/PD modelling.
    Equine veterinary journal, 1995, Volume: 27, Issue:4

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Clonixin; Cross-Over Studies; Dinoprostone; Exudates and Transudates; Glucuronidase; Half-Life; Horses; Inflammation; Ketoprofen; Leukotriene B4; Male; Models, Biological; Thromboxane B2

1995
Effects of the novel anti-inflammatory compounds, N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulphonamide (NS-398) and 5-methanesulphonamido-6-(2,4-difluorothio-phenyl)-1-inda none (L-745,337), on the cyclo-oxygenase activity of human blood prostaglandin
    British journal of pharmacology, 1995, Volume: 116, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Blotting, Western; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Induction; Female; Humans; In Vitro Techniques; Indans; Ketoprofen; Male; Middle Aged; Monocytes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Binding; Stereoisomerism; Sulfonamides; Thromboxane B2

1995
Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in calves.
    Chirality, 1995, Volume: 7, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Chromatography, High Pressure Liquid; Diffusion Chambers, Culture; Dinoprostone; Exudates and Transudates; Half-Life; Inflammation; Injections, Intravenous; Interleukin-6; Ketoprofen; Male; Stereoisomerism; Thromboxane B2; Tumor Necrosis Factor-alpha

1995
Protective activity of ketoprofen lysine salt against the pulmonary effects induced by bradykinin in guinea-pigs.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bronchoconstriction; Capillary Permeability; Cyclooxygenase Inhibitors; Guinea Pigs; Ketoprofen; Leukotriene C4; Lysine; Male; Thromboxane B2; Trachea

1996
The effect of ketoprofen creams on periodontal disease in rhesus monkeys.
    Journal of periodontal research, 1996, Volume: 31, Issue:8

    Topics: Administration, Topical; Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dental Plaque; Dinoprostone; Double-Blind Method; Edema; Emollients; Female; Follow-Up Studies; Gingival Crevicular Fluid; Gingival Hemorrhage; Gingivitis; Interleukin-1; Ketoprofen; Leukotriene B4; Macaca mulatta; Male; Molar; Periodontal Attachment Loss; Periodontitis; Placebos; Radiographic Image Enhancement; Random Allocation; Subtraction Technique; Thromboxane B2; Tumor Necrosis Factor-alpha; Vitamin E

1996
Effect of a conjugate of polymyxin B-dextran 70 in horses with experimentally induced endotoxemia.
    American journal of veterinary research, 1999, Volume: 60, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anticoagulants; Body Temperature; Cross-Over Studies; Cyclooxygenase Inhibitors; Dextrans; Drug Combinations; Endotoxemia; Female; Heart Rate; Hematocrit; Horse Diseases; Horses; Infusions, Intravenous; Interleukin-6; Ketoprofen; Leukocyte Count; Lipid A; Lipopolysaccharides; Male; Polymyxin B; Random Allocation; Thromboxane B2; Tumor Necrosis Factor-alpha

1999
Enantiospecific pharmacokinetics and pharmacodynamics of ketoprofen in sheep.
    Journal of veterinary pharmacology and therapeutics, 1999, Volume: 22, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chemistry, Pharmaceutical; Cross-Over Studies; Dinoprostone; Exudates and Transudates; Inflammation; Injections, Intravenous; Ketoprofen; Male; Sheep; Thromboxane B2

1999
Pharmacodynamics and pharmacokinetics of ketoprofen enantiomers in sheep.
    American journal of veterinary research, 2001, Volume: 62, Issue:1

    Topics: Animals; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Female; Half-Life; Isoenzymes; Ketoprofen; Metabolic Clearance Rate; Prostaglandin-Endoperoxide Synthases; Sheep; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2

2001
Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat.
    Journal of veterinary pharmacology and therapeutics, 2003, Volume: 26, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Diffusion Chambers, Culture; Dinoprostone; Dose-Response Relationship, Drug; Exudates and Transudates; Goats; Injections, Intravenous; Ketoprofen; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2

2003
Pharmacodynamics of flunixin and ketoprofen in mallard ducks (Anas platyrhynchos).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2001, Volume: 32, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Corticosterone; Ducks; Feces; Female; Hemoglobins; Injections, Intramuscular; Ketoprofen; Male; Muscle, Skeletal; Necrosis; Random Allocation; Thromboxane B2

2001
Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis.
    The Veterinary record, 2008, Oct-25, Volume: 163, Issue:17

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cattle; Endotoxins; Female; Injections, Intramuscular; Ketoprofen; Lactation; Mastitis, Bovine; Milk; Pain; Pain Measurement; Thromboxane B2

2008
In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study.
    Research in veterinary science, 2010, Volume: 88, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Etodolac; Isoenzymes; Ketoprofen; Kinetics; Lipopolysaccharides; Meloxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thiazines; Thiazoles; Thromboxane B2

2010
Dose-response investigation of oral ketoprofen in pigs challenged with Escherichia coli endotoxin.
    The Veterinary record, 2012, Jul-21, Volume: 171, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Endotoxins; Female; Ketoprofen; Male; Pain; Pain Measurement; Random Allocation; Swine; Swine Diseases; Thromboxane B2

2012