ketoprofen and sulindac

ketoprofen has been researched along with sulindac in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (16.22)	18.7374
1990's	3 (8.11)	18.2507
2000's	9 (24.32)	29.6817
2010's	17 (45.95)	24.3611
2020's	2 (5.41)	2.80

Authors

Authors	Studies
Duffy, EM; Jorgensen, WL	1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T	1
Bu, X; Cao, Y; Hu, X; Luo, M; Ren, Y; Song, Y; Wang, X; Xu, Q; Yuan, M	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Horie, T; Horiguchi, A; Kitamura, S; Kotake, Y; Ohshita, H; Ohta, S; Sanoh, S; Sugihara, K; Tateno, C; Tayama, Y	1
Kumar, M; Sinha, VR; Thareja, S	1
Alcaraz, B; Bratoeff, E; Cabeza, M; Camacho-Arroyo, I; Garrido, M; González-Arenas, A	1
Chen, T; Guan, J; Liao, J; Luo, J; Qin, X; Talley, JJ; Tortorella, MD; Tu, Z; Zhang, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Akgul, O; Alfawaz Altamimi, AS; Angeli, A; Bartolucci, G; Carta, F; Di Cesare Mannelli, L; Ghelardini, C; Scozzafava, A; Supuran, CT; Vullo, D	1
Ding, F; Gao, Y; He, X; Lei, Y; Li, S; Li, X; Li, Y; Li, Z; Wen, D; Zhang, Y; Zhong, M	1
Miehlke, K	1
Burdeĭnyĭ, AP	1
Pemberton, RE; Strand, LJ	1
Ahern, MJ; James, RH; Leslie, A; Rennie, GC; Roberts-Thomson, PJ; Wetherall, M	1
de Pouvourville, G	1
Anderson, SA; Brater, DC; Brown-Cartwright, D; Toto, RD	1
Ward, JR	1
Adamiec, R; Szewczyk, Z	1
Detrisac, CJ; Hawk, ET; Kelloff, GJ; McCormick, DL; Rao, KV; Steele, VE	1
Chen, YJ; Lin, CC; Lin, PC; Su, AK; Tseng, MC	1
Au, AL; Chan, SW; Kwan, YW; Lee, SM; Leung, GP; Li, RW; Seto, SW; Tse, CM	1
Andrews, PC; Ferrero, RL; Junk, PC; Kumar, I; Luu, Q; Nguyen, K; Taylor, JW	1
Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC	1
Du, G; Fang, Z; Gong, N; Lu, Y; Xing, C; Xing, W; Yu, H; Zhang, B	1

Reviews

3 review(s) available for ketoprofen and sulindac

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Drug therapy of ankylosing spondyloarthritis (Bechterew's disease)]. Terapevticheskii arkhiv, 1978, Volume: 50, Issue:12 Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Apazone; Butadienes; Cyclophosphamide; Diclofenac; Drug Combinations; Drug Evaluation; Glycolates; Gold; Humans; Ibuprofen; Indomethacin; Ketoprofen; Levamisole; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates; Spondylitis, Ankylosing; Sulindac	1978
Update on ibuprofen for rheumatoid arthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin	1984

Trials

4 trial(s) available for ketoprofen and sulindac

Article	Year
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents. Digestive diseases and sciences, 1979, Volume: 24, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin	1979
A comparison of ketoprofen SR and sulindac in the elderly with rheumatoid arthritis. The British journal of clinical practice, 1992,Winter, Volume: 46, Issue:4 Topics: Aged; Arthritis, Rheumatoid; Double-Blind Method; Female; Humans; Ketoprofen; Male; Sulindac; Treatment Outcome	1992
Update on ibuprofen for rheumatoid arthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin	1984
[Effectiveness of ketoprofen and sulindac treatment of patients with chronic glomerulopathies]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1984, Jul-09, Volume: 39, Issue:28 Topics: Adult; Chemical Phenomena; Chemistry; Chronic Disease; Clinical Trials as Topic; Female; Follow-Up Studies; Glomerulonephritis; Humans; Indenes; Ketoprofen; Male; Middle Aged; Phenylpropionates; Sulindac	1984

Other Studies

31 other study(ies) available for ketoprofen and sulindac

Article	Year
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney	2011
Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies. Bioorganic & medicinal chemistry, 2011, Feb-01, Volume: 19, Issue:3 Topics: Curcumin; Drug Design; Enzyme Inhibitors; Genetic Vectors; Humans; Inhibitory Concentration 50; Lactoylglutathione Lyase; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Molecular Targeted Therapy; Plasmids; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Animals; Cells, Cultured; Child, Preschool; Chimera; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drugs, Investigational; Female; Half-Life; Hepatocytes; Humans; Immunomagnetic Separation; Liver; Male; Metabolic Clearance Rate; Mice; Mice, SCID; Recombinant Proteins; Species Specificity; Urokinase-Type Plasminogen Activator	2012
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Effect of new hybrids based on 5,16-pregnadiene scaffold linked to an anti-inflammatory drug on the growth of a human astrocytoma cell line (U373). European journal of medicinal chemistry, 2015, Mar-26, Volume: 93 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Humans; Molecular Structure; Pregnadienes; Sulindac; Time Factors	2015
Synthesis and Evaluation of Novel Erlotinib-NSAID Conjugates as More Comprehensive Anticancer Agents. ACS medicinal chemistry letters, 2015, Oct-08, Volume: 6, Issue:10 Topics:	2015
Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis. Journal of medicinal chemistry, 2018, 06-14, Volume: 61, Issue:11 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbonic Anhydrase Inhibitors; Humans; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides	2018
Synthesis and biological evaluation of organoselenium (NSAIDs-SeCN and SeCF European journal of medicinal chemistry, 2020, Dec-15, Volume: 208 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; DNA; DNA Damage; Drug Screening Assays, Antitumor; Free Radical Scavengers; Humans; Interleukin-2; Molecular Docking Simulation; Organoselenium Compounds; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Thioredoxin Reductase 1	2020
Old and new pharmaceutical non-steroidal compounds prescribed for the management of patients with rheumatic diseases. Rheumatology and rehabilitation, 1979, Volume: Suppl Topics: Anti-Inflammatory Agents; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Naproxen; Rheumatic Diseases; Sulindac; Tolmetin	1979
The economic consequences of NSAID-induced gastropathy: the French context. Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96 Topics: Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Cost of Illness; Diclofenac; Duodenal Ulcer; Economics, Hospital; Etodolac; France; Gastrointestinal Diseases; Humans; Ketoprofen; Naproxen; National Health Programs; Piroxicam; Rheumatic Diseases; Sulindac	1992
Effects of nonsteroidal antiinflammatory drugs on renal function in patients with renal insufficiency and in cirrhotics. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1986, Volume: 8, Issue:5 Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Dinoprostone; Etodolac; Humans; Indomethacin; Ketoprofen; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Liver Cirrhosis, Alcoholic; Prostaglandins E; Sulindac	1986
Differential activity of aspirin, ketoprofen and sulindac as cancer chemopreventive agents in the mouse urinary bladder. Carcinogenesis, 1996, Volume: 17, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Butylhydroxybutylnitrosamine; Carcinogens; Diet; Humans; Ketoprofen; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Sulindac; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms	1996
Functionalized magnetic nanoparticles for small-molecule isolation, identification, and quantification. Analytical chemistry, 2007, May-01, Volume: 79, Issue:9 Topics: Flufenamic Acid; Humans; Ketoprofen; Macrolides; Magnetics; Mannose; Mefenamic Acid; Molecular Structure; Nanoparticles; Particle Size; Prednisolone; Robotics; Salicylamides; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulindac	2007
Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells. European journal of pharmacology, 2009, Jun-10, Volume: 612, Issue:1-3 Topics: Adenosine; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Cell Proliferation; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Etodolac; Humans; Indomethacin; Inhibitory Concentration 50; Ketoprofen; Kinetics; Mefenamic Acid; Muscle, Smooth, Vascular; Piroxicam; Sulindac; Temperature; Tetrazolium Salts; Thiazoles; Thioinosine	2009
Bismuth(III) complexes derived from non-steroidal anti-inflammatory drugs and their activity against Helicobacter pylori. Dalton transactions (Cambridge, England : 2003), 2010, Mar-21, Volume: 39, Issue:11 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bismuth; Calorimetry, Differential Scanning; Coordination Complexes; Drug Stability; Helicobacter Infections; Helicobacter pylori; Ketoprofen; Microbial Sensitivity Tests; Sulindac; Thermogravimetry	2010
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs. Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts	2012
An Evolving Role of Aqueous Piperazine to Improve the Solubility of Non-Steroidal Anti-Inflammatory Drugs. Journal of pharmaceutical sciences, 2022, Volume: 111, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Piperazine; Powders; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Sulindac; Water; X-Ray Diffraction	2022