ketoprofen and phenylbutazone

ketoprofen has been researched along with phenylbutazone in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	34 (41.98)	18.7374
1990's	15 (18.52)	18.2507
2000's	18 (22.22)	29.6817
2010's	12 (14.81)	24.3611
2020's	2 (2.47)	2.80

Authors

Authors	Studies
Kubo, S; Tagawa, H; Tsukada, W; Ueno, K; Yoshioka, T	1
Behn, DC; Botton, I; Fellows, CA; Laskowski, SC; Phillips, DK; Schlegel, DC; Speight, PT; Zenitz, BL	1
Inui, KI; Masuda, S; Saito, H	1
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S	1
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Inui, K; Saito, H; Uwai, Y	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Cha, SH; Endou, H; Hosoyamada, M; Khamdang, S; Kimura, H; Narikawa, S; Sekine, T; Takeda, M	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM	1
Chang, TK; Ensom, MH; Kiang, TK	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P	1
Kumar, M; Sinha, VR; Thareja, S	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Huskisson, EC	1
Akimoto, T; Saito, T; Tachizawa, H; Tsukada, W	1
Reinicke, C	1
Filosa, E; Ricciardi, S	1
Burdeĭnyĭ, AP	1
Pemberton, RE; Strand, LJ	1
Mörsdorf, K; Wolf, G	1
Peltola, P	4
Brath, HK; Haerum, LB; Straume, S; Sydnes, O	1
Burry, HC; Grahame, R	1
Placheta, P; Siegmeth, W	1
Grahame, R	1
Cardoe, N	1
Jessop, JD	1
Brath, HK; Haerum, LB; Straume, S; Sydnes, OA	1
Kitchen, EA; Meacock, SC	1
Guyonnet, JC; Julou, L	1
Binns, TB; Brooks, PM; Buchanan, WW; Mason, DI	1
Treadwell, BL; Tweed, JM	1
Remans, J	1
Janssen, PA; Niemegeers, CJ; Van Bruggen, JA	1
Awouters, F; Janssen, PA; Lenaerts, PM; Niemegeers, CJ	1
Hage, DS; Noctor, TA; Wainer, IW	1
Abdel-Moneam, NM; Mostafa, MH; Sheweita, SA	1
Paulus, HE; Schlegel, SI	1
Sallmann, AR	2
Court, H; Volans, GN	1
Radmanović, BZ; Sćepović, Z	1
Akbaraly, R; Brachet-Liermain, A; Laclau-Lacrouts, B; Leng, JJ; White, P	1
Lin, CC; Otagiri, M; Rahman, MH; Shin, YH; Yamasaki, K	1
Borne, AT; MacAllister, CG; Morgan, SJ; Pollet, RA	1
Kamerling, SG; Keowen, ML; Owens, JG; Stanton, SR	1
Kamerling, SG; Keowen, ML; Owens, JG; Prescott-Mathews, JS; Stanton, SR	1
Becker, L; Eberlein-König, B; Przybilla, B	1
Feron, VJ; Groene, EM; Horbach, GJ; Kappers, WA; Kleij, LA; Witkamp, RF; Zweers-Zeilmaker, WM	1
Bhagat, L; Lapwood, KR; Simpson, MP	1
Fox, SM; Johnston, SA	1
Craigmill, AL; Damian, P; Riviere, JE	1
Coghe, J; Deby-Dupont, G; Lekeux, P; Uystepruyst, C; Van de Weerdt, ML	1
Harmon, FA; Rakestraw, PC; Snyder, JR; Van Hoogmoed, L	1
Bae, SJ; Cho, U; Kang, K; Kim, WM; Kuettner, KE; Lee, DH; Lee, MH; Lee, MS; Nam, S; Schwartz, DE	1
Bertone, AL; Hardy, J; Moses, VS; Weisbrode, SE	1
Asakawa, N; Ishihama, Y; Miwa, T	1
Bruce, RA; Gregory, NG; Mellor, DJ; Stafford, KJ; Sutherland, MA; Ward, RN	1
Chambers, JP; Lizarraga, I	1
Boissevain, I	1
Bertucci, C; Pistolozzi, M	1
Davis, JL; Riviere, JE; Smith, GW; Tell, LA; Webb, AI	1
Dowling, G; Fabbrocino, S; Gallo, P; Regan, L; Serpe, L	1
Alinejad, A; Derakhshanfar, A; Morovati, M; Mozaffari, AA	1
Derakhshanfar, A; Mozaffari, AA	1
Maciążek-Jurczyk, M	1
Chudzik, M; Maciążek-Jurczyk, M; Równicka-Zubik, J; Sułkowska, A; Szkudlarek, A	1
Janas, K; Kulig, K; Maciążek-Jurczyk, M; Owczarzy, A; Pożycka, J; Rogóż, W; Szkudlarek, A	1
Du, G; Fang, Z; Gong, N; Lu, Y; Xing, C; Xing, W; Yu, H; Zhang, B	1

Reviews

9 review(s) available for ketoprofen and phenylbutazone

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
Antiinflammatory drugs. Seminars in arthritis and rheumatism, 1977, Volume: 7, Issue:1 Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Child; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylacetates; Phenylbutazone; Pregnancy; Pregnancy Complications; Propionates; Tolmetin	1977
[Nonsteroid antirheumatic agents]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1977, Jul-15, Volume: 32, Issue:14 Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fenoprofen; Flufenamic Acid; Humans; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylbutazone; Propionates; Salicylates	1977
[Drug therapy of ankylosing spondyloarthritis (Bechterew's disease)]. Terapevticheskii arkhiv, 1978, Volume: 50, Issue:12 Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Apazone; Butadienes; Cyclophosphamide; Diclofenac; Drug Combinations; Drug Evaluation; Glycolates; Gold; Humans; Ibuprofen; Indomethacin; Ketoprofen; Levamisole; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates; Spondylitis, Ankylosing; Sulindac	1978
Non-steroidal and analgesic therapy in the elderly. Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1 Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diclofenac; Drug Hypersensitivity; Gastrointestinal Diseases; Hematologic Diseases; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Diseases; Kinetics; Naproxen; Phenylbutazone; Piroxicam; Salicylates; Thiazines	1986
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review. The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika, 1983, Volume: 38, Issue:7 Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indomethacin; Ketoprofen; Oxyphenbutazone; Pain, Postoperative; Phenylbutazone	1983
Use of carprofen for the treatment of pain and inflammation in dogs. Journal of the American Veterinary Medical Association, 1997, May-15, Volume: 210, Issue:10 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamic Acid; Meloxicam; Naproxen; Osteoarthritis; Pain; Phenylbutazone; Piroxicam; Thiazines; Thiazoles	1997
Extralabel use of nonsteroidal anti-inflammatory drugs. Journal of the American Veterinary Medical Association, 1997, Oct-01, Volume: 211, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Clonixin; Dipyrone; Drug Approval; Drug Residues; Drug Utilization; Food Contamination; Goats; Ketoprofen; Meat; Milk; Phenylbutazone; Sheep; United States; United States Food and Drug Administration	1997

Trials

18 trial(s) available for ketoprofen and phenylbutazone

Article	Year
[Ketoprofen in rheumatic arthropathies in old age. Double-blind studies]. La Clinica terapeutica, 1977, Dec-31, Volume: 83, Issue:6 Topics: Aged; Arthritis; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Humans; Joint Diseases; Ketoprofen; Male; Middle Aged; Osteoarthritis; Phenylbutazone; Phenylpropionates; Spondylitis, Ankylosing	1977
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents. Digestive diseases and sciences, 1979, Volume: 24, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin	1979
A double-blind cross-over study of ketoprofen and phenylbutazone in rheumatoid arthritis. Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0 Topics: Analgesics; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic; Drug Evaluation; Gastrointestinal Diseases; Humans; Indomethacin; Ketoprofen; Phenylbutazone	1976
Clinical evaluation of ketoprofen (Orudis) in rheumatoid arthritis. Results of a multi-centre, double-blind, cross-over trial against phenylbutazone. Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0 Topics: Adult; Aged; Analgesics; Arthritis, Rheumatoid; Benzophenones; Capsules; Clinical Trials as Topic; Digestive System; Drug Evaluation; Female; Headache; Humans; Ketoprofen; Male; Middle Aged; Phenylbutazone; Time Factors	1976
Ketoprofen -- a new anti-rheumatic agent. Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0 Topics: Analgesics; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic; Drug Evaluation; Gastrointestinal Diseases; Hip Joint; Humans; Indomethacin; Ketoprofen; Osteoarthritis; Phenylbutazone	1976
[Double-blind trial: ketoprofen versus phenylbutazone in acute gouty arthritis (author's transl)]. Wiener klinische Wochenschrift, 1976, Sep-03, Volume: 88, Issue:16 Topics: Acute Disease; Adult; Aged; Arthritis; Benzophenones; Clinical Trials as Topic; Drug Evaluation; Drug Tolerance; Female; Gout; Humans; Injections, Intramuscular; Ketoprofen; Male; Middle Aged; Phenylbutazone	1976
Ketoprofen - clinical efficacy. Rheumatology and rehabilitation, 1976, Volume: Suppl Topics: Acetaminophen; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Benzophenones; Clinical Trials as Topic; Gout; Humans; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Placebos; Sciatica; Spondylitis, Ankylosing	1976
Double-blind cross-over study of ketoprofen and phenylbutazone in patients with chronic osteoarthrosis of the hip. Rheumatology and rehabilitation, 1976, Volume: Suppl Topics: Adult; Aged; Anti-Inflammatory Agents; Benzophenones; Chronic Disease; Clinical Trials as Topic; Female; Hip Joint; Humans; Ketoprofen; Male; Middle Aged; Osteoarthritis; Phenylbutazone	1976
Double-blind study of ketoprofen and phenylbutazone in ankylosing spondylitis. Rheumatology and rehabilitation, 1976, Volume: Suppl Topics: Adult; Anti-Inflammatory Agents; Benzophenones; Clinical Trials as Topic; Female; Humans; Ketoprofen; Male; Middle Aged; Phenylbutazone; Spondylitis, Ankylosing	1976
Clinical evaluation of keto profen (Orudis) in rheumatoid arthritis: results of a multi-centre double-blind trial against phenylbutazone. Rheumatology and rehabilitation, 1976, Volume: Suppl Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic; Female; Humans; Ketoprofen; Male; Middle Aged; Phenylbutazone	1976
Double-blind cross-over study of ketoprofen and phenylbutazone in rheumatoid arthritis. Rheumatology and rehabilitation, 1976, Volume: Suppl Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic; Humans; Ketoprofen; Phenylbutazone	1976
Long-term treatment with ketoprofen in rheumatoid arthritis. A clinical trial with special reference to side-effects. Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0 Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Benzophenones; Clinical Trials as Topic; Diarrhea; Drug Evaluation; Headache; Humans; Ketoprofen; Long-Term Care; Phenylbutazone	1976
Ketoprofen (Orudis) in ankylosing spondylitis. The New Zealand medical journal, 1975, May-14, Volume: 81, Issue:539 Topics: Adult; Benzophenones; Blood Sedimentation; Clinical Trials as Topic; Female; Humans; Ketoprofen; Male; Middle Aged; Phenylbutazone; Spine; Spondylitis, Ankylosing	1975
Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses. American journal of veterinary research, 1996, Volume: 57, Issue:6 Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Horse Diseases; Horses; Joints; Ketoprofen; Lameness, Animal; Leukotriene B4; Male; Phenylbutazone; Proteins; Synovial Fluid; Synovitis	1996
Ketoprofen and phenylbutazone attenuation of PAF-induced lung inflammation in calves. Veterinary journal (London, England : 1997), 1999, Volume: 157, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Dinoprostone; Ketoprofen; Leukotriene B4; Male; Phenylbutazone; Placebos; Platelet Activating Factor; Pneumonia; Respiration; Thromboxane B2	1999
Cortisol responses to dehorning of calves given a 5-h local anaesthetic regimen plus phenylbutazone, ketoprofen, or adrenocorticotropic hormone prior to dehorning. Research in veterinary science, 2002, Volume: 73, Issue:2 Topics: Adrenocorticotropic Hormone; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Cattle; Drug Interactions; Drug Therapy, Combination; Female; Horns; Hydrocortisone; Inflammation; Ketoprofen; Lidocaine; Male; Phenylbutazone; Stress, Physiological; Time Factors	2002
Involvement of opioidergic and alpha2-adrenergic mechanisms in the central analgesic effects of non-steroidal anti-inflammatory drugs in sheep. Research in veterinary science, 2006, Volume: 80, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Female; Imidazoles; Injections, Intravenous; Injections, Spinal; Ketoprofen; Naloxone; Narcotic Antagonists; ortho-Aminobenzoates; Pain; Phenylbutazone; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Salicylic Acid; Sheep	2006
A comparative study on the adverse effects of flunixin, ketoprofen and phenylbutazone in miniature donkeys: haematological, biochemical and pathological findings. New Zealand veterinary journal, 2010, Volume: 58, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Double-Blind Method; Equidae; Gastrointestinal Diseases; Ketoprofen; Kidney Diseases; Male; Phenylbutazone; Splenic Diseases	2010

Other Studies

54 other study(ies) available for ketoprofen and phenylbutazone

Article	Year
6,11-Dihydro-11-oxodibenz [b,e] oxepinacetic acids with potent antiinflammatory activity. Journal of medicinal chemistry, 1976, Volume: 19, Issue:7 Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dibenzoxepins; Edema; Female; Lethal Dose 50; Male; Mice; Rats; Spasm; Stomach Ulcer; Structure-Activity Relationship	1976
Bulky amine analogues of ketoprofen: potent antiinflammatory agents. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Edema; Indicators and Reagents; Ketoprofen; Magnetic Resonance Spectroscopy; Male; Phenylpropionates; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1984
Interactions of nonsteroidal anti-inflammatory drugs with rat renal organic anion transporter, OAT-K1. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:3 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Drug Interactions; Indomethacin; Ketoprofen; Kidney; Male; Methotrexate; Rats; Rats, Wistar; Tetraethylammonium Compounds	1997
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Molecular pharmacology, 1999, Volume: 55, Issue:5 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter. European journal of pharmacology, 2000, Dec-01, Volume: 409, Issue:1 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Carrier Proteins; Kinetics; Methotrexate; Oocytes; Probenecid; Uricosuric Agents; Xenopus laevis	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Characterization of methotrexate transport and its drug interactions with human organic anion transporters. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Humans; Indomethacin; Kinetics; Liver-Specific Organic Anion Transporter 1; Methotrexate; Mice; Mice, Transgenic; Nerve Tissue Proteins; Organic Anion Transporters, Sodium-Independent; Phenylbutazone; Potassium Channels; Potassium Channels, Tandem Pore Domain; Probenecid	2002
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints. Journal of medicinal chemistry, 2004, Sep-23, Volume: 47, Issue:20 Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions. Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21 Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence	2010
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Prostaglandin synthetase systems in rat and rabbit renal medulla and inhibition by non-steroidal anti-inflammatory drugs. Japanese journal of pharmacology, 1977, Volume: 27, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Ketoprofen; Kidney; Kidney Medulla; Male; Microsomes; Phenylbutazone; Prostaglandins E; Prostaglandins F; Rabbits; Rats	1977
[On the efficiency of new antiinflammatory agents. A comparative study (author's transl)]. Arzneimittel-Forschung, 1977, Volume: 27, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Benzylidene Compounds; Carrageenan; Diclofenac; Edema; Fenoprofen; In Vitro Techniques; Indenes; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Protease Inhibitors; Rats	1977
Ketoprofen experiences. Rheumatology and rehabilitation, 1978, Volume: Suppl Topics: Aspirin; Humans; Indomethacin; Ketoprofen; Phenylbutazone; Phenylpropionates	1978
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration. Agents and actions, 1976, Volume: 6, Issue:1-3 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen; Indomethacin; Ketoprofen; Leukocytes; Male; Methotrexate; Naproxen; Phenylbutazone; Pleurisy; Rats	1976
Relationship between the inhibitory activity on 'RCS' and prostaglandins synthesis and the anti-inflammatory activity of ketoprofen and several other non-steroidal anti-inflammatory agents. Rheumatology and rehabilitation, 1976, Volume: Suppl Topics: Abscess; Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Benzophenones; Colon; Guinea Pigs; Hydroxy Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Ketoprofen; Lung; Muscle Contraction; Naproxen; Phenylbutazone; Prostaglandin Antagonists; Prostaglandins; Pyrans	1976
Sensible prescribing. The treatment of rheumatoid arthritis. The Practitioner, 1975, Volume: 215, Issue:1286 Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Arthroplasty; Aspirin; Cryotherapy; Exercise Therapy; Humans; Hydrostatic Pressure; Immunosuppressive Agents; Indomethacin; Injections, Intra-Articular; Ketoprofen; Methylprednisolone; Oxyphenbutazone; Penicillamine; Phenylbutazone; Pressure	1975
[Review of the clinical studies in rheumatoid arthritis with several non steroid anti-inflammatory agents (author's transl)]. Journal belge de rhumatologie et de medecine physique = Belgisch tijdschrift voor reumatologie en fysische geneeskunde, 1975, Volume: 30 Spec no Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Evaluation; Humans; Indomethacin; Ketoprofen; Phenylbutazone; Pyrroles	1975
Suprofen, a potent antagonist of acetic acid-induced writhing in rats. Arzneimittel-Forschung, 1975, Volume: 25, Issue:10 Topics: Acetates; Analgesics; Animals; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Indomethacin; Ketoprofen; Male; Muscle Contraction; Phenylacetates; Phenylbutazone; Phenylpropionates; Prostaglandin Antagonists; Prostaglandins; Rats; Spasm; Thiophenes; Tolmetin	1975
Suprofen, a potent antagonist of ultraviolet-erythema in guinea-pigs. Arzneimittel-Forschung, 1975, Volume: 25, Issue:10 Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythema; Guinea Pigs; Indomethacin; Ketoprofen; Male; Phenylbutazone; Phenylpropionates; Thiophenes; Time Factors; Tolmetin; Ultraviolet Rays	1975
Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase. Journal of chromatography, 1992, Jun-10, Volume: 577, Issue:2 Topics: Allosteric Site; Binding, Competitive; Caprylates; Chromatography, High Pressure Liquid; Humans; Ketoprofen; Oxazepam; Pharmaceutical Preparations; Phenylbutazone; Serum Albumin; Stereoisomerism; Suprofen; Tolbutamide; Warfarin	1992
Influence of some anti-inflammatory drugs on the activity of aryl hydrocarbon hydroxylase and the cytochrome P450 content. Environmental research, 1990, Volume: 52, Issue:1 Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Injections, Intraperitoneal; Ketoprofen; Male; Mice; Microsomes, Liver; Phenylbutazone; Piroxicam; Pyrazoles	1990
The history of diclofenac. The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B Topics: Chemical Phenomena; Chemistry; Diclofenac; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Piroxicam; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Thiazines	1986
The history of diclofenac. Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1 Topics: Diclofenac; History, 20th Century; Ibuprofen; Ketoprofen; Models, Molecular; Naproxen; Phenylbutazone; Piroxicam; Solubility; Structure-Activity Relationship; Thiazines	1985
Poisoning after overdose with non-steroidal anti-inflammatory drugs. Adverse drug reactions and acute poisoning reviews, 1984,Spring, Volume: 3, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin	1984
Interaction between reserpine and non-steroidal anti-inflammatory agents in producing gastric ulcers in rats. European journal of pharmacology, 1984, Mar-02, Volume: 98, Issue:3-4 Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Synergism; Female; Indomethacin; Ketoprofen; Phenylbutazone; Rats; Reserpine; Stomach Ulcer	1984
[Trans-placental transfer of four anti-inflammatory agents. A study carried out by in vitro perfusion (author's transl)]. Journal de gynecologie, obstetrique et biologie de la reproduction, 1981, Volume: 10, Issue:1 Topics: Anti-Inflammatory Agents; Female; Humans; Indomethacin; Ketoprofen; Oxyphenbutazone; Perfusion; Phenylbutazone; Placenta; Pregnancy	1981
Characterization of high affinity binding sites of non-steroidal anti-inflammatory drugs with respect to site-specific probes on human serum albumin. Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Ketoprofen; Phenylbutazone; Serum Albumin; Software	1993
Comparison of adverse effects of phenylbutazone, flunixin meglumine, and ketoprofen in horses. Journal of the American Veterinary Medical Association, 1993, Jan-01, Volume: 202, Issue:1 Topics: Animals; Anorexia; Blood Proteins; Clonixin; Female; Gastric Mucosa; Gastroscopy; Horse Diseases; Horses; Ketoprofen; Kidney Pelvis; Male; Mouth Diseases; Mouth Mucosa; Necrosis; Phenylbutazone; Random Allocation; Stomach Diseases	1993
Effects of ketoprofen and phenylbutazone on chronic hoof pain and lameness in the horse. Equine veterinary journal, 1995, Volume: 27, Issue:4 Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Female; Foot Diseases; Hoof and Claw; Horse Diseases; Horses; Ketoprofen; Lameness, Animal; Male; Multivariate Analysis; Pain; Pain Measurement; Phenylbutazone	1995
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light. Acta dermato-venereologica, 1996, Volume: 76, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dermatitis, Phototoxic; Diclofenac; Erythrocytes; Hemolysis; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Light; Naproxen; Phenylbutazone; Photosensitizing Agents; Piroxicam; Propionates	1996
Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10. Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:12 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cell Line; Cricetinae; Cricetulus; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Diclofenac; Drug Interactions; Enzyme Inhibitors; Flurbiprofen; Gene Expression; Humans; Hydroxylation; Ketoprofen; Lung; Methylation; Mixed Function Oxygenases; Phenylbutazone; Sulfaphenazole; Tolbutamide; Transfection	1996
Analgesic effects on endogenous melatonin secretion. Journal of pineal research, 1997, Volume: 22, Issue:1 Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Buprenorphine; Darkness; Female; Ketoprofen; Melatonin; Phenylbutazone; Sheep	1997
In vitro effects of nonsteroidal anti-inflammatory agents and prostaglandins I2, E2, and F2alpha on contractility of taenia of the large colon of horses. American journal of veterinary research, 1999, Volume: 60, Issue:8 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Clonixin; Colon; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Epoprostenol; Horses; Indomethacin; Ketoprofen; Muscle Contraction; Muscle, Smooth; Phenylbutazone; Prostaglandins	1999
Molecular characteristics of the inhibition of human neutrophil elastase by nonsteroidal antiinflammatory drugs. Experimental & molecular medicine, 2000, Sep-30, Volume: 32, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Affinity; Computer Simulation; Enzyme Inhibitors; Humans; Isoenzymes; Ketoprofen; Leukocyte Elastase; Models, Molecular; Naproxen; Phenylbutazone; Salicylates; Spectrum Analysis, Raman	2000
Effects of anti-inflammatory drugs on lipopolysaccharide-challenged and -unchallenged equine synovial explants. American journal of veterinary research, 2001, Volume: 62, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Carbazoles; Clonixin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Horses; Hyaluronic Acid; Isoenzymes; Ketoprofen; Lipopolysaccharides; Meloxicam; Methylprednisolone; Organ Culture Techniques; Phenylbutazone; Prostaglandin-Endoperoxide Synthases; Synovial Membrane; Thiazines; Thiazoles	2001
Drug-plasma protein binding assay by electrokinetic chromatography-frontal analysis. Electrophoresis, 2002, Volume: 23, Issue:6 Topics: beta-Cyclodextrins; Blood Proteins; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Diclofenac; Electrophoresis, Capillary; Humans; Ketoprofen; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Serum Albumin; Sulfathiazole; Sulfathiazoles; Warfarin	2002
[Adverse effects]. Tijdschrift voor diergeneeskunde, 2005, Oct-15, Volume: 130, Issue:20 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Dogs; Drug Interactions; Ketoprofen; Netherlands; Phenylbutazone	2005
Species-dependent stereoselective drug binding to albumin: a circular dichroism study. Chirality, 2008, Volume: 20, Issue:3-4 Topics: Animals; Bilirubin; Cattle; Circular Dichroism; Diazepam; Dogs; Humans; Ketoprofen; Kinetics; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Rats; Serum Albumin; Species Specificity; Stereoisomerism	2008
Extralabel use of nonsteroidal anti-inflammatory drugs in cattle. Journal of the American Veterinary Medical Association, 2008, Mar-01, Volume: 232, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Clonixin; Dipyrone; Drug Approval; Drug Residues; Drug Utilization; Food Contamination; Ketoprofen; Meat; Meloxicam; Phenylbutazone; Thiazines; Thiazoles; United States; United States Food and Drug Administration	2008
Determination of ibuprofen, ketoprofen, diclofenac and phenylbutazone in bovine milk by gas chromatography-tandem mass spectrometry. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2008, Volume: 25, Issue:12 Topics: Animals; Cattle; Diclofenac; Drug Residues; Food Analysis; Food Contamination; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Milk; Phenylbutazone; Sensitivity and Specificity; Tandem Mass Spectrometry	2008
Evaluation of the brain, renal, and hepatic effects of flunixin meglumine, ketoprofen, and phenylbutazone administration in Iranian fat-tailed sheep. Tropical animal health and production, 2011, Volume: 43, Issue:7 Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Chemical Analysis; Brain; Clonixin; Female; Iran; Ketoprofen; Kidney; Liver; Phenylbutazone; Sheep, Domestic; Urinalysis; Veterinary Drugs	2011
Phenylbutazone and ketoprofen binding to serum albumin. Fluorescence study. Pharmacological reports : PR, 2014, Volume: 66, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Drug Interactions; Humans; Ketoprofen; Phenylbutazone; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence	2014
Effects of non-enzymatic glycation in human serum albumin. Spectroscopic analysis. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, Jan-05, Volume: 152 Topics: Anti-Inflammatory Agents, Non-Steroidal; Fluorescent Dyes; Glycated Serum Albumin; Glycation End Products, Advanced; Glycosylation; Humans; Ketoprofen; Models, Molecular; Naphthalenesulfonates; Phenylbutazone; Prohibitins; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence	2016
Human Serum Albumin Aggregation/Fibrillation and its Abilities to Drugs Binding. Molecules (Basel, Switzerland), 2020, Jan-31, Volume: 25, Issue:3 Topics: Amyloid; Binding Sites; Dansyl Compounds; Fluorescence; Humans; Ketoprofen; Kinetics; Ligands; Phenylbutazone; Prohibitins; Proline; Protein Binding; Serum Albumin, Human	2020
An Evolving Role of Aqueous Piperazine to Improve the Solubility of Non-Steroidal Anti-Inflammatory Drugs. Journal of pharmaceutical sciences, 2022, Volume: 111, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Piperazine; Powders; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Sulindac; Water; X-Ray Diffraction	2022