ketoprofen and lysine

ketoprofen has been researched along with lysine in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19909 (19.57)18.7374
1990's9 (19.57)18.2507
2000's8 (17.39)29.6817
2010's17 (36.96)24.3611
2020's3 (6.52)2.80

Authors

AuthorsStudies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Arrigo, A; Cabitza, P; Parrini, M; Vanasia, M1
Blomgren, H; Hammarström, S; Petrini, B; Rotstein, S; Wasserman, J1
Cosentina, R; Memeo, A1
Guarino, A; Nannei, AM; Viganò, R1
Borsa, M; Carrabba, M; Chevallard, M; Malandrino, S; Mele, G; Tonon, GC1
Giudice, G; Rizzi, F1
Rizzi, F; Rossi, S; Tadini, R1
Bruni, G; Liverta, C; Magrini, M; Moretti, MP; Movilia, PG; Rivolta, G1
Borsa, M; Malandrino, S; Ronchi, C; Tonon, GC; Zanolo, G1
Borsa, M; Canali, S; Ronchi, C; Tonon, GC; Zanolo, G1
Bruni, G; Liverta, C; Magrini, M; Pavesi, G1
Bestetti, A; Clavenna, G; Daffonchio, L; Fedele, G; Ferrari, MP; Omini, C1
Carnelli, VE; Cera, R; Clemente, E; Mei, VA; Previtali, M1
de' Lorenzi, C; Fatti, F; Ghirardini, M; Martini, A1
Berti, F; Clavenna, G; Daffonchio, L; Omini, C; Rossoni, G1
Anfossi, P; Carli, S; Montesissa, C; Villa, R1
de' Lorenzi, C; Natale, F1
Boltri, L; Caselli, G; Clavenna, G; Coppola, A; Del Rosario, M; Gentile, M; Melillo, G; Pallottini, V; Pellegrini, L; Porzio, S1
Bellussi, L; Damiani, V; Passàli, D; Passàli, GC; Volonté, M1
Bertuglia, S; Daffonchio, L; Novellini, R1
Anacardio, R; Bartolini, S; Carlucci, G; Gentile, MM; Mazzeo, P; Perilli, O1
Busoni, P; Fedele, G; Gallini, C; Grossetti, R; Ivani, G; Maestri, L; Messeri, A; Murolo, S; Noccioli, B; Novellini, R1
Berardi, R; Carle, F; Cascinu, S; Cellerino, R; Pietroselli, D; Piga, A; Pulita, F; Romagnoli, E1
Abou El Hassan, MA; Bast, A; Berkhof, J; Bruynzeel, AM; Niessen, HW; Schalkwijk, C; van der Vijgh, WJ1
Aquino, RP; Colombo, P; Del Gaudio, P; Rosaria Lauro, M; Russo, P1
Polli, JE; Zheng, X1
Forsberg, M; Gynther, M; Jalkanen, A; Knuuti, J; Laine, K; Lehtonen, M; Leppänen, J; Rautio, J; Ropponen, J1
Börje, A; Goossens, A; Karlsson, I; Mårtensson, J; Vanden Broecke, K1
Carozzino, L; Del Vecchio, A; Della Casa Alberighi, O; Dionisio, P; Freschi, F; Jamone, R; Martini, A; Picollo, G; Ruperto, N; Salvatori, E; Zera, M1
Aquino, RP; Del Gaudio, P; Mencherini, T; Russo, P; Sansone, F; Stigliani, M1
Bespalova, NA; Durnovo, EA; Gliavina, IA; Iartseva, AV; Khomutinnikova, NE; Marochkina, MS; Shashurina, SV1
Boĭko, AN; Gandzhula, PA; Kamchatnov, PR; Khozova, A; Otcheskaia, OV; Petrov, SV; Trubetskaia, EA1
Isozaki, T; Osanai, Y; Shinoda, M; Suzuki, T1
Merkulov, YA; Merkulova, DM; Onsin, AA1
Goto, T; Lee, SH; Oe, T; Osaki, F1
Alekseev, AV; Alekseev, VV; Gol'dzon, GD1
Espinoza, MA; Santa Cruz, LA; Velásquez, GC1
Allegretti, M; Antonosante, A; Benedetti, E; Brandolini, L; Cimini, A; Cristiano, L; Fidoamore, A; Gentile, R; Giordano, A; Menghini, P1
Aquino, RP; Casciaro, R; Del Gaudio, P; Galietta, L; Garofalo, E; Incarnato, L; Manniello, MD; Minicucci, L; Russo, P; Stigliani, M; Zegarra-Moran, O1
Allegretti, M; Antonosante, A; Aramini, A; Benedetti, E; Brandolini, L; Castelli, V; Catanesi, M; Cimini, A; Cristiano, L; d'Angelo, M; Giordano, A; Luini, A; Mayo, E; Parashuraman, S; Villa, S1
Altobelli, R; Ambrosio, L; Calcagnile, P; Caputo, T; Demitri, C; Guarino, V1
Cossellu, G; Cozza, P; Farronato, M; Gaffuri, F; Lanteri, V; Lione, R; Ugolini, A1
Kuczyńska, J; Nieradko-Iwanicka, B1
Allegretti, M; Aramini, A; Bagnasco, M; Boccella, S; Cattani, F; Ferrari, MP; Goisis, G; Minnella, EM; Novelli, R; Pace, V1
Allegretti, M; Aramini, A; Bianchini, G; Boccella, S; Bordignon, S; Brandolini, L; Canestrari, D; Castelli, V; Chierotti, MR; Cimini, A; Cocchiaro, P; d'Angelo, M; d'Egidio, F; Dragani, MC; Lillini, S; Luongo, L; Maione, S; Mattioli, S; Novelli, R; Pacchiarotti, N; Palmerio, F; Tomassetti, M1

Reviews

1 review(s) available for ketoprofen and lysine

ArticleYear
[Naproxen sodium compared with ketoprofen lysine and lysine acetylsalicylate in the management of postoperative pain in gynecologic surgery].
    Minerva ginecologica, 1988, Volume: 40, Issue:5

    Topics: Clinical Trials as Topic; Drug Evaluation; Female; Genital Diseases, Female; Humans; Ketoprofen; Lysine; Naproxen; Pain, Postoperative; Phenylpropionates

1988

Trials

16 trial(s) available for ketoprofen and lysine

ArticleYear
[Efficacy and tolerability of ketoprofen lysine salt foam for topical use in the treatment of traumatic pathologies of the locomotor apparatus].
    La Clinica terapeutica, 1992, Volume: 141, Issue:9

    Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Tolerance; Female; Humans; Joints; Ketoprofen; Lysine; Male; Middle Aged; Time Factors; Wounds and Injuries

1992
[Ketoprofen, tromethamine tiaprofenate, versus lysine acetyl salicylate in the control of postoperative pain].
    Minerva anestesiologica, 1987, Volume: 53, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Aspirin; Double-Blind Method; Drug Combinations; Female; Gynecology; Humans; Ketoprofen; Lysine; Middle Aged; Pain, Postoperative; Phenylpropionates; Propionates; Random Allocation; Tromethamine

1987
[Naproxen sodium compared with ketoprofen lysine and lysine acetylsalicylate in the management of postoperative pain in gynecologic surgery].
    Minerva ginecologica, 1988, Volume: 40, Issue:5

    Topics: Clinical Trials as Topic; Drug Evaluation; Female; Genital Diseases, Female; Humans; Ketoprofen; Lysine; Naproxen; Pain, Postoperative; Phenylpropionates

1988
Successful treatment of biliary colic with intravenous ketoprofen or lysine acetylsalicylate.
    Current medical research and opinion, 1985, Volume: 9, Issue:7

    Topics: Adult; Aged; Analgesics; Aspirin; Biliary Tract Diseases; Clinical Trials as Topic; Colic; Double-Blind Method; Female; Humans; Injections, Intravenous; Ketoprofen; Lysine; Male; Middle Aged; Pain; Phenylpropionates

1985
Intravenous ketoprofen in renal colic: a placebo-controlled pilot study.
    Clinical therapeutics, 1984, Volume: 6, Issue:4

    Topics: Adult; Aged; Analgesics; Aspirin; Clinical Trials as Topic; Colic; Female; Humans; Ketoprofen; Kidney Diseases; Lysine; Male; Middle Aged; Phenylpropionates

1984
[Effects of various dosage of ketoprofen salt suppositories in acute inflammatory disease in infants (3-36 month old) and children (3-13 year old)].
    Minerva pediatrica, 1995, Volume: 47, Issue:5

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents; Body Temperature; Child; Child, Preschool; Dose-Response Relationship, Drug; Fever; Humans; Infant; Ketoprofen; Lysine; Respiratory Tract Infections; Urologic Diseases

1995
[Gastric endoscopic assessment after treatment with orally administered ketoprofen lysine salt (80 mg granular sachet). Controlled study vs placebo].
    Minerva medica, 1994, Volume: 85, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dosage Forms; Double-Blind Method; Drug Administration Schedule; Female; Gastric Mucosa; Gastroscopy; Humans; Ketoprofen; Lysine; Male

1994
[The efficacy of and tolerance for ketoprofen lysine salt in solution for oropharyngeal use in inflammatory lesions of the oral cavity].
    Minerva stomatologica, 1997, Volume: 46, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Tolerance; Female; Humans; Ketoprofen; Lysine; Male; Middle Aged; Mouthwashes; Remission Induction; Stomatitis

1997
Efficacy and safety of ketoprofen lysine salt mouthwash versus benzydamine hydrochloride mouthwash in acute pharyngeal inflammation: a randomized, single-blind study.
    Clinical therapeutics, 2001, Volume: 23, Issue:9

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Infective Agents, Local; Anti-Inflammatory Agents, Non-Steroidal; Benzydamine; Female; Humans; Ketoprofen; Lysine; Male; Middle Aged; Mouthwashes; Pain Measurement; Pharyngitis; Remission Induction; Single-Blind Method

2001
Analgesic efficacy and tolerability of ketoprofen lysine salt vs paracetamol in common paediatric surgery. A randomized, single-blind, parallel, multicentre trial.
    Paediatric anaesthesia, 2003, Volume: 13, Issue:7

    Topics: Acetaminophen; Administration, Rectal; Adolescent; Analgesics, Non-Narcotic; Anesthesia, Epidural; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Child; Female; Humans; Ketoprofen; Lysine; Male; Minor Surgical Procedures; Pain Measurement; Pain, Postoperative; Prospective Studies; Single-Blind Method; Time Factors; Treatment Outcome

2003
A randomized, double-blind, placebo-controlled trial of paracetamol and ketoprofren lysine salt for pain control in children with pharyngotonsillitis cared by family pediatricians.
    Italian journal of pediatrics, 2011, Sep-29, Volume: 37

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Ambulatory Care; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Double-Blind Method; Family Practice; Female; Humans; Ketoprofen; Lysine; Male; Pain; Pediatrics; Pharyngitis; Placebos; Time Factors; Tonsillitis; Treatment Outcome

2011
[The clinical estimation of ketoprofen lysine salt effect on the intensitivity of acute pain syndrome in the oral cavity during surgical procedures and postoperative period].
    Stomatologiia, 2013, Volume: 92, Issue:1

    Topics: Acute Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ketoprofen; Lysine; Male; Middle Aged; Mouth; Oral Surgical Procedures; Pain Threshold; Syndrome; Young Adult

2013
[Efficacy of ketoprofen lysine salt (artrosilene) in the treatment of nonspecific vertebrogenic pain syndromes in outpatients].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2013, Volume: 113, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Female; Humans; Ketoprofen; Lysine; Male; Middle Aged; Outpatients; Treatment Outcome

2013
[Piascledin in the treatment of chronic dorsalgia].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2013, Volume: 113, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Drug Combinations; Female; Humans; Ketoprofen; Lysine; Male; Middle Aged; Phytosterols; Plant Extracts; Vitamin E

2013
Ketoprofen is more effective than diclofenac after oral surgery when used as a preemptive analgesic: a pilot study.
    Journal of oral & facial pain and headache, 2014,Spring, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Diclofenac; Double-Blind Method; Female; Humans; Injections, Intramuscular; Ketoprofen; Lysine; Male; Mandible; Molar, Third; Pain Measurement; Pain, Postoperative; Pilot Projects; Premedication; Time Factors; Tooth Extraction; Young Adult

2014
Efficacy of ketoprofen lysine salt and paracetamol/acetaminophen to reduce pain during rapid maxillary expansion: A randomized controlled clinical trial.
    International journal of paediatric dentistry, 2019, Volume: 29, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Female; Humans; Ketoprofen; Lysine; Male; Pain Management; Pain Perception; Palatal Expansion Technique; Prospective Studies

2019

Other Studies

30 other study(ies) available for ketoprofen and lysine

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
In vitro capacity of various cyclooxygenase inhibitors to revert immune suppression caused by radiation therapy for breast cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1990, Volume: 19, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Breast Neoplasms; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Immune Tolerance; In Vitro Techniques; Indomethacin; Ketoprofen; Lymphocyte Activation; Lysine; Meclofenamic Acid; Middle Aged; Phytohemagglutinins

1990
[Ketoprofen lysine treatment of painful manifestations of spinal osteoarthrosis].
    La Clinica terapeutica, 1988, Jul-31, Volume: 126, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Evaluation; Female; Humans; Ketoprofen; Lysine; Male; Middle Aged; Osteoarthritis; Pain; Phenylpropionates; Spinal Diseases; Time Factors

1988
[Use of laser therapy associated with a lysine ketoprofen gel in various pathologies of orthopedic importance].
    La Clinica terapeutica, 1986, Jul-15, Volume: 118, Issue:1

    Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Evaluation Studies as Topic; Female; Gels; Humans; Ketoprofen; Laser Therapy; Lysine; Male; Middle Aged; Periarthritis; Phenylpropionates; Tendinopathy

1986
Effectiveness and tolerability of ketoprofen lysine, once a day, in patients with rheumatic disorders.
    Drugs under experimental and clinical research, 1987, Volume: 13, Issue:5

    Topics: Drug Administration Schedule; Drug Tolerance; Female; Humans; Ketoprofen; Lysine; Male; Middle Aged; Phenylpropionates; Rheumatic Diseases

1987
[Pharmacologic and pharmacokinetic activity of ketoprofen lysine salt for topical administration].
    Il Farmaco; edizione pratica, 1983, Volume: 38, Issue:2

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Female; Guinea Pigs; Ketoprofen; Kinetics; Lysine; Male; Phenylpropionates; Rabbits; Rats; Rats, Inbred Strains

1983
Pharmacokinetics of a slow-release preparation of ketoprofen lysine in man.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:10

    Topics: Adult; Biological Availability; Delayed-Action Preparations; Humans; Ketoprofen; Kinetics; Lysine; Male; Middle Aged; Phenylpropionates

1983
Effects of a new foam formulation of ketoprofen lysine salt in experimental models of inflammation and hyperalgesia.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Exudates and Transudates; Female; Gastric Mucosa; Gels; Hyperalgesia; Inflammation; Ketoprofen; Lysine; Male; Prostaglandins; Rats; Rats, Sprague-Dawley; Substance P

1995
Protective activity of ketoprofen lysine salt against the pulmonary effects induced by bradykinin in guinea-pigs.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bronchoconstriction; Capillary Permeability; Cyclooxygenase Inhibitors; Guinea Pigs; Ketoprofen; Leukotriene C4; Lysine; Male; Thromboxane B2; Trachea

1996
Intramuscular bioavailability of ketoprofen lysine salt in horses.
    The veterinary quarterly, 1997, Volume: 19, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Biological Availability; Cross-Over Studies; Female; Half-Life; Horses; Injections, Intramuscular; Injections, Intravenous; Ketoprofen; Lysine

1997
Efficacy of a new topical gel-spray formulation of ketoprofen lysine salt in the rat: percutaneous permeation in vitro and in vivo and pharmacological activity.
    Pharmacological research, 1998, Volume: 37, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Gels; In Vitro Techniques; Inflammation; Ketoprofen; Lysine; Pain Threshold; Rats; Rats, Sprague-Dawley; Skin; Skin Absorption; Stomach

1998
Protective effect of ketoprofen lysine salt on interleukin-1beta and bradykinin induced inflammatory changes in hamster cheek pouch microcirculation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Cricetinae; Humans; Inflammation; Interleukin-1; Ketoprofen; Lysine; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Platelet Membrane Glycoproteins; Protein Synthesis Inhibitors; Receptor, Bradykinin B2; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Interleukin-1

2002
Physicochemical compatibility between ketoprofen lysine salt injections (Artrosilene) and pharmaceutical products frequently used for combined therapy by intravenous administration.
    Journal of pharmaceutical and biomedical analysis, 2003, Aug-21, Volume: 32, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Injections, Intravenous; Ketoprofen; Lysine; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet

2003
Effective prevention of 5-fluorouracil-induced superficial phlebitis by ketoprofen lysine salt gel.
    The American journal of medicine, 2003, Oct-01, Volume: 115, Issue:5

    Topics: Administration, Topical; Aged; Antimetabolites, Antineoplastic; Arm; Female; Fluorouracil; Humans; Infusions, Intravenous; Ketoprofen; Lysine; Male; Thrombophlebitis

2003
Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Cardiomyopathies; Dexamethasone; Doxorubicin; Glycation End Products, Advanced; Hydroxyethylrutoside; Immunohistochemistry; Ketoprofen; Lysine; Male; Mice; Mice, Inbred BALB C; Myocytes, Cardiac

2007
Encapsulation of ketoprofen and ketoprofen lysinate by prilling for controlled drug release.
    AAPS PharmSciTech, 2009, Volume: 10, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Delayed-Action Preparations; Ketoprofen; Lysine; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical

2009
Synthesis and in vitro evaluation of potential sustained release prodrugs via targeting ASBT.
    International journal of pharmaceutics, 2010, Aug-30, Volume: 396, Issue:1-2

    Topics: Animals; Biological Transport; Caco-2 Cells; Chemistry, Pharmaceutical; Chenodeoxycholic Acid; Delayed-Action Preparations; Dogs; Drug Carriers; Drug Compounding; Drug Stability; Humans; Hydrolysis; Ketoprofen; Kinetics; Liver; Lysine; Niacin; Organic Anion Transporters, Sodium-Dependent; Prodrugs; Rats; Solubility; Symporters; Taurocholic Acid; Technology, Pharmaceutical; Transfection

2010
Brain uptake of ketoprofen-lysine prodrug in rats.
    International journal of pharmaceutics, 2010, Oct-31, Volume: 399, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Brain; Drug Carriers; Injections, Intravenous; Ketoprofen; Large Neutral Amino Acid-Transporter 1; Lysine; Male; Molecular Structure; Perfusion; Prodrugs; Protein Binding; Rats; Rats, Wistar

2010
Clinical and experimental studies of octocrylene's allergenic potency.
    Contact dermatitis, 2011, Volume: 64, Issue:6

    Topics: Acrylates; Adult; Aged; Animals; Benzophenones; Child; Child, Preschool; Dermatitis, Allergic Contact; Dermatitis, Photoallergic; Female; Humans; Ketoprofen; Local Lymph Node Assay; Lysine; Male; Mice; Middle Aged; Patch Tests; Skin; Sunscreening Agents; Young Adult

2011
Non-steroidal anti-inflammatory drug for pulmonary administration: design and investigation of ketoprofen lysinate fine dry powders.
    International journal of pharmaceutics, 2013, May-01, Volume: 448, Issue:1

    Topics: Administration, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Cell Line; Cell Proliferation; Cystic Fibrosis; Drug Compounding; Drug Design; Dry Powder Inhalers; Humans; Ketoprofen; Leucine; Lysine; Microscopy, Electron, Scanning; Mucus; Particle Size; Powders

2013
Photochemical reaction of 2-(3-benzoylphenyl)propionic acid (ketoprofen) with basic amino acids and dipeptides.
    The journal of physical chemistry. B, 2013, Aug-22, Volume: 117, Issue:33

    Topics: Amino Acids, Basic; Anserine; Arginine; Carnosine; Dipeptides; Histidine; Ketoprofen; Lysine; Quantum Theory

2013
Predicted multiple selected reaction monitoring to screen activated drug-mediated modifications on human serum albumin.
    Analytical biochemistry, 2014, Mar-15, Volume: 449

    Topics: Amino Acid Sequence; Benzoquinones; Binding Sites; Cysteine; Humans; Imines; Ketoprofen; Lysine; Mass Spectrometry; Molecular Sequence Data; Pharmaceutical Preparations; Protein Binding; Serum Albumin

2014
[Nonspecific low-back pain: from symptomatic treatment to pathogenesis-based treatment].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2014, Volume: 114, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Drug Therapy, Combination; Female; Humans; Ketoprofen; Low Back Pain; Lysine; Male; Middle Aged; Phytosterols; Plant Extracts; Treatment Outcome; Vitamin E

2014
Gastroprotective effects of L-lysine salification of ketoprofen in ethanol-injured gastric mucosa.
    Journal of cellular physiology, 2015, Volume: 230, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Ethanol; Gastric Mucosa; Humans; Ketoprofen; Lipid Peroxidation; Lysine; Nitric Oxide

2015
Rheological Properties of Cystic Fibrosis Bronchial Secretion and in Vitro Drug Permeation Study: The Effect of Sodium Bicarbonate.
    Journal of aerosol medicine and pulmonary drug delivery, 2016, Volume: 29, Issue:4

    Topics: Administration, Inhalation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Cystic Fibrosis; Dry Powder Inhalers; Elastic Modulus; Female; Humans; Ketoprofen; Lysine; Male; Middle Aged; Models, Biological; Permeability; Rheology; Sodium Bicarbonate; Sputum; Viscosity; Young Adult

2016
Differential protein modulation by ketoprofen and ibuprofen underlines different cellular response by gastric epithelium.
    Journal of cellular physiology, 2018, Volume: 233, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cell Survival; Cytoprotection; Drug Combinations; Epithelial Cells; Ethanol; Gastric Mucosa; Gene Expression Profiling; Gene Regulatory Networks; Humans; Ibuprofen; Ketoprofen; Lysine; MCF-7 Cells; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Time Factors; Transcriptome

2018
Core/shell cellulose-based microspheres for oral administration of Ketoprofen Lysinate.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2018, Volume: 106, Issue:7

    Topics: Administration, Oral; Cellulose; Chitosan; Delayed-Action Preparations; Hydrogen-Ion Concentration; Ketoprofen; Lysine; Microspheres

2018
The effect of ketoprofen lysine salt on mucosa of rat stomach after ethyl alcohol intoxication.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 141

    Topics: Alcoholic Intoxication; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Ethanol; Gastric Mucosa; Ketoprofen; Lysine; Male; Membrane Proteins; Rats; Rats, Wistar

2021
Ketoprofen lysine salt has a better gastrointestinal and renal tolerability than ketoprofen acid: A comparative tolerability study in the Beagle dog.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dogs; Ketoprofen; Kidney; Lysine; Stomach

2022
Ketoprofen, lysine and gabapentin co-crystal magnifies synergistic efficacy and tolerability of the constituent drugs: Pre-clinical evidences towards an innovative therapeutic approach for neuroinflammatory pain.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 163

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Gabapentin; Ketoprofen; Lysine; Neuralgia; Neuroinflammatory Diseases; Rats; Tissue Distribution

2023