ketoprofen has been researched along with flurbiprofen in 94 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (10.64) | 18.7374 |
1990's | 17 (18.09) | 18.2507 |
2000's | 33 (35.11) | 29.6817 |
2010's | 28 (29.79) | 24.3611 |
2020's | 6 (6.38) | 2.80 |
Authors | Studies |
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Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
Duffy, EM; Jorgensen, WL | 1 |
Topliss, JG; Yoshida, F | 1 |
Cihlar, T; Ho, ES; Mulato, AS | 1 |
Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N | 1 |
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
Chang, TK; Ensom, MH; Kiang, TK | 1 |
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A | 1 |
Caron, G; Ermondi, G | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Carrupt, PA; Martel, S; Ottaviani, G | 1 |
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Gozalbes, R; Pineda-Lucena, A | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
Kumar, M; Sinha, VR; Thareja, S | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Headey, SJ; Hughes, ML; Laguerre, A; Mohanty, B; Patil, R; Porter, CJ; Scanlon, MJ; Wielens, J; Williams, ML | 1 |
Brewster, C; Deering-Rice, CE; Reilly, CA; Rose, TM | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Anderson, JA; Buchanan, WW; Lee, P; Miller, J; Webb, J | 1 |
Mushin, A; Williams, H; Zutshi, D | 1 |
Ho, C; Hwang, GC | 1 |
Brune, K; Geisslinger, G; Menzel-Soglowek, S; Mollenhauer, J | 1 |
Fritz, ME; Green, MD; Mayambala, CS; Odle, BM; Offenbacher, S; Sena, FJ; Smith, MA; van Dyke, TE; Yeh, KC | 1 |
Blessington, B; Crabb, N; Karkee, S; Northage, A | 1 |
Borisiuk, BE; Bulakh, EP; Levin, IV; Perepel'chenko, AI; Ternovoĭ, NK | 1 |
Fujii, M; Matsumoto, M; Mori, T; Sawada, Y; Terai, H | 1 |
Berry, BW; Jamali, F | 1 |
Chiba, K; Higuchi, N; Kikuchi, S; Miyazaki, S; Nishimura, S; Takada, M | 1 |
Capell, HA; Hunter, JA; Madhok, R; Pullar, T; Zoma, AA | 1 |
Cherubino, P; Longoni, A | 1 |
Whittle, BJ | 1 |
Cicala, C; Cirino, G; Grisham, MB; McKnight, W; Reuter, B; Wallace, JL | 1 |
Bradley, JD; Brater, DC; Greene, PK; Tracy, TS; Worster, T | 1 |
Brune, K; Geisslinger, G; Menzel-Soglowek, S | 1 |
Beck, WS; Brune, K; Geisslinger, G; Menzel, S | 1 |
Baydoun, AR; Cirino, G; Del Soldato, P; Wallace, JL; Wheeler-Jones, CP | 1 |
Cabré, F; Carabaza, A; García, ML; Gómez, M; Gutiérrez, M; Mauleón, D; Rotllan, E | 1 |
Davies, NM; Jamali, F; Russell, AS; Wright, MR | 1 |
Feron, VJ; Groene, EM; Horbach, GJ; Kappers, WA; Kleij, LA; Witkamp, RF; Zweers-Zeilmaker, WM | 1 |
Borgå, B; Borgå, O | 1 |
Caubet, JF; Handley, DA; Jerussi, TP; McCray, JE | 1 |
Hubbard, JW; McKay, G; Midha, KK; Rawson, MJ | 1 |
el-Bary, AA; el-Nabarawi, MA; Mohamed, MI | 1 |
Cabré, F; Díaz, I; Fernández-Guasti, A; López-Muñoz, FJ; Mauleón, D; Tost, D; Ventura, R | 1 |
Allegretti, M; Bertini, R; Biordi, L; Caselli, G; Martinotti, S; Marullo, A; Mascagni, P; Sabbatini, V | 1 |
Bannwarth, B; Jarry, C; Péhourcq, F | 1 |
Cabré, F; Holzer, P; Jocic, M; Mauléon, D | 1 |
Lozano, JJ; Pouplana, R; Ruiz, J | 1 |
Abushoffa, AM; Crommen, J; Fillet, M; Hubert, P; Servais, AC | 1 |
Bateman, SD; Erck, R; Li, T; Morris, KR; Wang, JJ | 1 |
Goto, J; Kim, J; Kim, JH; Kim, KR; La, S | 1 |
Bateman, SD; Guillot, MA; Morris, KR; Wang, JJ | 1 |
Kobayashi, D; Kogo, T; Morimoto, Y; Numajiri, S; Shimamura, T; Tairabune, T; Ueda, H | 1 |
Bagheri, H; Lacroix, I; Lapeyre-Mestre, M; Montastruc, JL; Pathak, A | 1 |
Kim, KR; Nguyen, DT; Paik, MJ | 1 |
Chikamatsu, N; Igarashi, T; Nagata, O; Nakazawa, T; Shimo, T; Yamamoto, M | 1 |
Avondo, S; Cardile, V; Garufi, F; Gentile, B; Panico, AM; Ronsisvalle, S | 1 |
Balchen, M; Gjelstad, A; Pedersen-Bjergaard, S; Rasmussen, KE | 1 |
De Simone, C; Famularo, G; Minisola, G; Nicotra, GC | 1 |
Jin, YX; Tang, YH; Zeng, S | 1 |
Cárdenas, S; Cruz-Vera, M; Lucena, R; Valcárcel, M | 1 |
Fanali, S; Rocco, A | 1 |
Angeletti, M; Censi, R; Di Martino, P; Gashi, Z; Gobetto, R; Malaj, L; Masic, A; Mozzicafreddo, M | 1 |
Higashi, K; Ideura, S; Moribe, K; Waraya, H; Yamamoto, K | 1 |
Goi, N; Ishii, T; Morishita, K; Saitoh, K; Taniguchi, A | 1 |
Alcudia-León, MC; Cárdenas, S; Lucena, R; Riaño, S; Valcárcel, M | 1 |
Bouchet, LM; de la Guardia, M; Delgado-Pérez, T; Galian, RE; Pérez-Prieto, J | 1 |
Gaš, B; Riesová, M; Svobodová, J; Tošner, Z; Ušelová, K; Zusková, I | 1 |
Gjelstad, A; Pedersen-Bjergaard, S; Roldán-Pijuán, M | 1 |
Higashi, K; Liu, N; Moribe, K; Ueda, K | 1 |
Hachuła, B | 1 |
Canotilho, J; Castro, RAE; Eusébio, MES; Machado, SMT; Maria, TMR | 1 |
Iwaki, M; Kawase, A; Kobayashi, Y; Ogiso, T; Shimada, H; Tanahashi, S | 1 |
Ask, KS; Gjelstad, A; Pedersen-Bjergaard, S; Øiestad, EL | 1 |
Fukumoto, A; Hori, M; Kaku, S; Matsumoto, H; Tajima, K; Toda, Y | 1 |
Alshana, U; Hassan, M | 1 |
Chen, Q; Lin, F; Lu, X; Wang, B; Wu, W; Yang, X; Ye, F; Zhao, S | 1 |
Carrasco-Correa, EJ; Giesbers, M; Herrero-Martínez, JM; Simó-Alfonso, EF | 1 |
Barlow, DJ; Jackson, PJM; Pysz, I; Rahman, KM; Thurston, DE | 1 |
Chaturvedi, K; Dave, RH; Morris, KR; Shah, HS | 1 |
Bădulescu, M; Stefan-van Staden, RI; Ţuchiu, BM; van Staden, JF | 1 |
Du, G; Fang, Z; Gong, N; Lu, Y; Xing, C; Xing, W; Yu, H; Zhang, B | 1 |
Gorenflo, M; Saur, P; van den Anker, JN; van Dyk, M; Welzel, T; Ziesenitz, VC | 1 |
4 review(s) available for ketoprofen and flurbiprofen
Article | Year |
---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The impact of stereoisomerism in bioequivalence studies.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Doxepin; Flurbiprofen; Humans; Hydroxychloroquine; Ketoprofen; Nadolol; Nortriptyline; Propafenone; Stereoisomerism; Therapeutic Equivalency | 1998 |
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain | 2022 |
5 trial(s) available for ketoprofen and flurbiprofen
Article | Year |
---|---|
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Mefenamic Acid; Pain; Phenylacetates; Placebos; Prednisone; Salicylates | 1976 |
[Use of flugalin and profenid in patients with rheumatoid arthritis].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Flurbiprofen; Humans; Ketoprofen; Male; Middle Aged; Phenylpropionates; Propionates | 1988 |
Have the newer NSAIDS contributed to the management of rheumatoid arthritis?
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Feprazone; Flurbiprofen; Humans; Ketoprofen; Patient Dropouts; Phenylbutyrates; Propionates; Random Allocation | 1985 |
Methotrexate disposition following concomitant administration of ketoprofen, piroxicam and flurbiprofen in patients with rheumatoid arthritis.
Topics: Administration, Oral; Adult; Aged; Arthritis, Rheumatoid; Drug Interactions; Drug Therapy, Combination; Female; Fluorescence Polarization Immunoassay; Flurbiprofen; Humans; Ketoprofen; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Piroxicam | 1994 |
Clinical endoscopic evaluation of the gastroduodenal tolerance to (R)- ketoprofen, (R)- flurbiprofen, racemic ketoprofen, and paracetamol: a randomized, single-blind, placebo-controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Duodenal Diseases; Duodenal Ulcer; Endoscopy, Gastrointestinal; Flurbiprofen; Gastrointestinal Hemorrhage; Humans; Ketoprofen; Male; Middle Aged; Placebos; Single-Blind Method; Stereoisomerism; Stomach Diseases; Stomach Ulcer | 1998 |
85 other study(ies) available for ketoprofen and flurbiprofen
Article | Year |
---|---|
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship | 2000 |
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors | 2003 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.
Topics: Fatty Acid-Binding Proteins; Fluorescent Dyes; Humans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spectrometry, Fluorescence | 2014 |
Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates.
Topics: Amidohydrolases; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Flurbiprofen; Humans; Serotonin; TRPV Cation Channels | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Ophthalmic screening of patients receiving ketoprofen or flurbiprofen medication for inflammatory and degenerative joint diseases.
Topics: Adult; Aged; Analgesics; Arthritis; Benzophenones; Cornea; Eye; Female; Flurbiprofen; Follow-Up Studies; Humans; Joint Diseases; Ketoprofen; Lens, Crystalline; Male; Middle Aged; Propionates; Retina; Time Factors; Visual Acuity | 1976 |
Development of extended-release solid dispersions of nonsteroidal antiinflammatory drugs with aqueous polymeric dispersions: optimization of drug release via a curve-fitting technique.
Topics: Acrylic Resins; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Carriers; Flurbiprofen; Ketoprofen; Kinetics; Particle Size; Polymers; Suspensions | 1992 |
Metabolic chiral inversion of 2-arylpropionates in rat H4IIE and human Hep G2 hepatoma cells. Relationship to in vivo metabolism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Rats; Species Specificity; Stereoisomerism; Tumor Cells, Cultured | 1992 |
Inhibition of human periodontal prostaglandin E2 synthesis with selected agents.
Topics: Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Eicosapentaenoic Acid; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Meclofenamic Acid; Naproxen; Periodontitis; Periodontium; Vitamin E | 1990 |
Chromatographic approaches to the quality control of chiral propionate anti-inflammatory drugs and herbicides.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Chromatography, Gas; Flurbiprofen; Herbicides; Ibuprofen; Ketoprofen; Quality Control; Stereoisomerism | 1989 |
The properties of solid dispersions of indomethacin, ketoprofen and flurbiprofen in phosphatidylcholine.
Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Flurbiprofen; Indomethacin; Ketoprofen; Phenylpropionates; Phosphatidylcholines; Powders; Propionates | 1988 |
Stereospecific high-performance liquid chromatographic (HPLC) assay of flurbiprofen in biological specimens.
Topics: Chromatography, High Pressure Liquid; Flurbiprofen; Humans; Ketoprofen; Propionates; Stereoisomerism | 1988 |
Study of the interactions between sulfamethizole and three anti-inflammatory propionic acid derivatives at the renal level in rats.
Topics: Animals; Anti-Inflammatory Agents; Drug Interactions; Flurbiprofen; Ketoprofen; Male; Phenylbutyrates; Propionates; Rats; Rats, Inbred Strains; Sulfamethizole; Sulfathiazoles | 1985 |
[Flurbiprofen and ketoprofen per os and rectum: efficacy and tolerability in spondyloarthrosis].
Topics: Administration, Oral; Adult; Aged; Drug Evaluation; Female; Flurbiprofen; Humans; Ketoprofen; Male; Middle Aged; Phenylpropionates; Propionates; Spondylitis; Suppositories | 1983 |
Arachidonic acid metabolites and the gastro-intestinal toxicity of anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Digestive System; Flurbiprofen; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Ketoprofen; Naproxen; Prostaglandins; Rats | 1981 |
Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Flurbiprofen; Ketoprofen; Leukocytes; Male; Nitrates; Nitrites; Nitrogen Oxides; Platelet Aggregation; Prostaglandins; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship | 1994 |
Metabolic chiral inversion of 2-arylpropionates in different tumor cell lines.
Topics: Animals; Carcinoma, Hepatocellular; Cell Count; Culture Media; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Liver Neoplasms; Liver Neoplasms, Experimental; Propionates; Rats; Species Specificity; Stereoisomerism; Tumor Cells, Cultured | 1993 |
Stereoselectivity of biliary excretion of 2-arylpropionates in rats.
Topics: Animals; Bile; Flurbiprofen; Ibuprofen; Injections, Intravenous; Ketoprofen; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1993 |
Inhibition of inducible nitric oxide synthase expression by novel nonsteroidal anti-inflammatory derivatives with gastrointestinal-sparing properties.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cell Line; Enzyme Induction; Escherichia coli; Flurbiprofen; Ketoprofen; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites | 1996 |
Stereoselective inhibition of inducible cyclooxygenase by chiral nonsteroidal antiinflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Guinea Pigs; Humans; Isoenzymes; Ketoprofen; Ketorolac; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sheep; Stereoisomerism; Tolmetin | 1996 |
Effect of the enantiomers of flurbiprofen, ibuprofen, and ketoprofen on intestinal permeability.
Topics: Animals; Dose-Response Relationship, Drug; Flurbiprofen; Ibuprofen; Intestinal Absorption; Ketoprofen; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1996 |
Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cell Line; Cricetinae; Cricetulus; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Diclofenac; Drug Interactions; Enzyme Inhibitors; Flurbiprofen; Gene Expression; Humans; Hydroxylation; Ketoprofen; Lung; Methylation; Mixed Function Oxygenases; Phenylbutazone; Sulfaphenazole; Tolbutamide; Transfection | 1996 |
Serum protein binding of nonsteroidal antiinflammatory drugs: a comparative study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chromatography, High Pressure Liquid; Diclofenac; Female; Fenoprofen; Flurbiprofen; Humans; Ketoprofen; Male; Middle Aged; Naproxen; Protein Binding; Tolmetin | 1997 |
Effect of chemical structure on the release of certain propionic acid derivatives from their dosage forms.
Topics: Capsules; Chemical Phenomena; Chemistry, Physical; Dosage Forms; Drug Compounding; Drug Stability; Drug Storage; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Molecular Structure; Naproxen; Propionates; Suppositories | 1998 |
Antinociceptive effects of S(+)-ketoprofen and other analgesic drugs in a rat model of pain induced by uric acid.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Biotransformation; Disease Models, Animal; Dose-Response Relationship, Drug; Flurbiprofen; Injections, Intraventricular; Ketoprofen; Ketorolac; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stereoisomerism; Tolmetin; Tromethamine; Uric Acid | 1998 |
R- and S-isomers of nonsteroidal anti-inflammatory drugs differentially regulate cytokine production.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dinoprostone; Female; Flurbiprofen; Ibuprofen; In Vitro Techniques; Interleukin-10; Interleukin-6; Ketoprofen; Lipopolysaccharides; Macrophages, Peritoneal; Mice; RNA, Messenger; Stereoisomerism; Tumor Necrosis Factor-alpha | 2000 |
Chiral resolution of flurbiprofen and ketoprofen enantiomers by HPLC on a glycopeptide-type column chiral stationary phase.
Topics: Buffers; Chromatography, High Pressure Liquid; Drug Stability; Flurbiprofen; Furans; Glycopeptides; Hydrogen-Ion Concentration; Indicators and Reagents; Ketoprofen; Nitrates; Sensitivity and Specificity; Stereoisomerism | 2001 |
Estimation of acute flurbiprofen and ketoprofen toxicity in rat gastric mucosa at therapy-relevant doses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Gastric Mucosa; Injections, Subcutaneous; Intubation, Gastrointestinal; Isoenzymes; Ketoprofen; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Stereoisomerism; Stomach Ulcer; Sulfonamides | 2001 |
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2002 |
Enhancement of selectivity and resolution in the enantioseparation of uncharged compounds using mixtures of oppositely charged cyclodextrins in capillary electrophoresis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclodextrins; Electrophoresis, Capillary; Fenoprofen; Flurbiprofen; Ibuprofen; Ketoprofen; Static Electricity; Stereoisomerism | 2003 |
Modeling of adhesion in tablet compression--I. Atomic force microscopy and molecular simulation.
Topics: Adhesiveness; Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Flurbiprofen; Ibuprofen; Iron; Ketoprofen; Microscopy, Atomic Force; Models, Molecular; Surface Properties; Tablets; X-Ray Diffraction | 2003 |
Simultaneous chiral discrimination of multiple profens by cyclodextrin-modified capillary electrophoresis in normal and reversed polarity modes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclodextrins; Electrophoresis, Capillary; Flurbiprofen; Hexadimethrine Bromide; Ibuprofen; Ketoprofen; Phenylpropionates; Stereoisomerism | 2003 |
Modeling of adhesion in tablet compression. II. Compaction studies using a compaction simulator and an instrumented tablet press.
Topics: Adhesiveness; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Drug Compounding; Flurbiprofen; Ibuprofen; Ketoprofen; Lubrication; Pressure; Surface Properties; Tablets | 2004 |
Investigation of the release test method for the topical application of pharmaceutical preparations: release test of cataplasm including nonsteroidal anti-inflammatory drugs using artificial sweat.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Kinetics; Solubility; Sweat; Tablets | 2004 |
Nonsteroidal anti-inflammatory drug-induced liver injury: a case-control study in primary care.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cholestasis; Diclofenac; Drug Therapy, Combination; Female; Flurbiprofen; Hepatocytes; Humans; Ibuprofen; Ketoprofen; Liver; Male; Meloxicam; Middle Aged; Niflumic Acid; Primary Health Care; Salicylates; Sex Distribution; Statistics, Nonparametric; Thiazines; Thiazoles; Time Factors | 2004 |
Enantioseparation of flurbiprofen and ketoprofen in patches and in urine excretions by achiral gas chromatography.
Topics: Chromatography, Gas; Flurbiprofen; Humans; Ketoprofen; Male; Reproducibility of Results; Stereoisomerism | 2004 |
Study on the mechanism of photosensitive dermatitis caused by ketoprofen in the guinea pig.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Phototoxic; Dose-Response Relationship, Drug; Female; Flurbiprofen; Guinea Pigs; Ketoprofen; Phenylpropionates; Skin; Stereoisomerism; Ultraviolet Rays | 2006 |
"In vitro" differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cell Survival; Cells, Cultured; Chondrocytes; Dinoprostone; Femur Head; Flurbiprofen; Glycosaminoglycans; Humans; Interleukin-1beta; Ketoprofen; Matrix Metalloproteinase 3; Nitrites; Reactive Oxygen Species; Stereoisomerism | 2005 |
Electrokinetic migration of acidic drugs across a supported liquid membrane.
Topics: Acids; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Flurbiprofen; Gemfibrozil; Heptanol; Hydrogen-Ion Concentration; Ketoprofen; Membranes, Artificial; Naproxen; Pharmaceutical Preparations; Probenecid; Reproducibility of Results; Warfarin | 2007 |
Cross-reaction allergic pancreatitis with ketoprofen and flurbiprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Budesonide; Cross Reactions; Female; Flurbiprofen; Humans; Hypersensitivity; Ketoprofen; Middle Aged; Pancreatitis; Scopolamine Derivatives; Tiotropium Bromide; Treatment Outcome | 2007 |
Analysis of flurbiprofen, ketoprofen and etodolac enantiomers by pre-column derivatization RP-HPLC and application to drug-protein binding in human plasma.
Topics: Acetonitriles; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Buffers; Chromatography, High Pressure Liquid; Ethylamines; Ethyldimethylaminopropyl Carbodiimide; Etodolac; Flurbiprofen; Humans; Hydrogen-Ion Concentration; Ketoprofen; Naphthalenes; Protein Binding; Reproducibility of Results; Solvents; Stereoisomerism; Sulfur Oxides; Triazoles | 2008 |
Ionic liquid-based dynamic liquid-phase microextraction: application to the determination of anti-inflammatory drugs in urine samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Fractionation; Flurbiprofen; Humans; Hydrogen-Ion Concentration; Indomethacin; Ionic Liquids; Ketoprofen; Molecular Structure; Naproxen; Phenylbutyrates; Reproducibility of Results; Tolmetin | 2008 |
Enantiomeric separation of acidic compounds by nano-liquid chromatography with methylated-beta-cyclodextrin as a mobile phase additive.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; beta-Cyclodextrins; Carbazoles; Chromatography, Liquid; Flurbiprofen; Hydrogen-Ion Concentration; Indoprofen; Ketoprofen; Methylation; Molecular Structure; Nanotechnology; Naproxen; Propionates; Stereoisomerism; Suprofen; Time Factors | 2009 |
Differences in the interaction between aryl propionic acid derivatives and poly(vinylpyrrolidone) K30: A multi-methodological approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Carbon Isotopes; Crystallization; Drug Stability; Flurbiprofen; Hot Temperature; Humidity; Hydrogen Bonding; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Molecular Structure; Molecular Weight; Naproxen; Phase Transition; Phenylbutyrates; Polymers; Povidone; Static Electricity; X-Ray Diffraction | 2009 |
Structural evaluation of crystalline ternary γ-cyclodextrin complex.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Chemical Precipitation; Excipients; Flurbiprofen; gamma-Cyclodextrins; Ketoprofen; Magnetic Resonance Spectroscopy; Molecular Conformation; Naproxen; Pharmaceutic Aids; Powder Diffraction; Salicylic Acid; Spectroscopy, Fourier Transform Infrared; Water | 2011 |
Evaluation of percutaneous permeation of flurbiprofen and ketoprofen after application of transdermal patches using a lateral sectioning approach in hairless rats.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Delivery Systems; Flurbiprofen; Ketoprofen; Male; Permeability; Rats; Rats, Hairless; Skin Absorption; Tissue Distribution; Transdermal Patch | 2010 |
Determination of non-steroidal anti-inflammatory drugs in urine by the combination of stir membrane liquid-liquid-liquid microextraction and liquid chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Flurbiprofen; Humans; Indomethacin; Ketoprofen; Limit of Detection; Liquid Phase Microextraction; Naproxen | 2012 |
Sensing chiral drugs by using CdSe/ZnS nanoparticles capped with N-acetyl-L-cysteine methyl ester.
Topics: Acetylcysteine; Cadmium Compounds; Circular Dichroism; Esters; Flurbiprofen; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Quantum Dots; Selenium Compounds; Spectrometry, Fluorescence; Stereoisomerism; Sulfides; Zinc Compounds | 2013 |
Determination of thermodynamic values of acidic dissociation constants and complexation constants of profens and their utilization for optimization of separation conditions by Simul 5 Complex.
Topics: Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Computer Simulation; Electrophoresis, Capillary; Flurbiprofen; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Naproxen; Osmolar Concentration; Software; Thermodynamics; Viscosity | 2014 |
Parallel artificial liquid membrane extraction of acidic drugs from human plasma.
Topics: Calibration; Chromatography, High Pressure Liquid; Diclofenac; Equipment Design; Flurbiprofen; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Liquid-Liquid Extraction; Membranes, Artificial; Pharmaceutical Preparations; Polypropylenes; Polyvinyls | 2015 |
Effect of guest drug character encapsulated in the cavity and intermolecular spaces of γ-cyclodextrins on the dissolution property of ternary γ-cyclodextrin complex.
Topics: Chemistry, Pharmaceutical; Drug Carriers; Flurbiprofen; gamma-Cyclodextrins; Ketoprofen; Naproxen; Salicylamides; Solubility | 2017 |
The nature of hydrogen-bonding interactions in nonsteroidal anti-inflammatory drugs revealed by polarized IR spectroscopy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Crystallography, X-Ray; Deuterium; Flurbiprofen; Hydrogen Bonding; Ketoprofen; Naproxen; Spectrophotometry, Infrared; Vibration | 2018 |
Levetiracetam+nonsteroidal anti-inflammatory drug binary systems: A contribution to the development of new solid dosage forms.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Drug Combinations; Drug Liberation; Flurbiprofen; Ibuprofen; Ketoprofen; Levetiracetam; Naproxen; Piracetam; Stereoisomerism | 2017 |
Correlation between glucuronidation and covalent adducts formation with proteins of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Flurbiprofen; Glucuronides; Ibuprofen; Ketoprofen; Male; Microsomes, Liver; Naproxen; Propionates; Protein Binding; Rats, Wistar | 2018 |
Dried blood spots and parallel artificial liquid membrane extraction-A simple combination of microsampling and microextraction.
Topics: Amitriptyline; Chromatography, High Pressure Liquid; Dried Blood Spot Testing; Fenoprofen; Flurbiprofen; Healthy Volunteers; Humans; Ibuprofen; Ketoprofen; Liquid-Liquid Extraction; Membranes, Artificial; Quetiapine Fumarate; Tandem Mass Spectrometry | 2018 |
Analgesic effect of S (+)-flurbiprofen plaster in a rat model of knee arthritis: analysis of gait and synovial fluid prostaglandin E
Topics: Analgesics; Animals; Arthritis, Experimental; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Flurbiprofen; Gait; Ketoprofen; Male; Phenylpropionates; Rats; Synovial Fluid; Transdermal Patch | 2018 |
Switchable-hydrophilicity solvent liquid-liquid microextraction of non-steroidal anti-inflammatory drugs from biological fluids prior to HPLC-DAD determination.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Centrifugation; Chromatography, High Pressure Liquid; Etodolac; Flurbiprofen; Humans; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Ketoprofen; Linear Models; Liquid Phase Microextraction; Milk, Human; Organic Chemicals; Reproducibility of Results; Saliva; Sodium Hydroxide; Solvents | 2019 |
Facile synthesis of magnetic carbon nanotubes derived from ZIF-67 and application to magnetic solid-phase extraction of profens from human serum.
Topics: Adsorption; Cobalt; Flurbiprofen; Humans; Imidazoles; Ketoprofen; Magnets; Metal Nanoparticles; Nanotubes, Carbon; Organometallic Compounds; Solid Phase Extraction | 2020 |
Hybrid monoliths with metal-organic frameworks in spin columns for extraction of non-steroidal drugs prior to their quantitation by reversed-phase HPLC.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Limit of Detection; Metal-Organic Frameworks; Methylmethacrylates; Solid Phase Microextraction | 2019 |
UPLC-based assay to assess the hydrophobicity of Antibody-Drug Conjugate (ADC) payloads.
Topics: Biological Assay; Calicheamicins; Chromatography, High Pressure Liquid; Doxorubicin; Flurbiprofen; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Immunoconjugates; Irinotecan; Ketoprofen; Maytansine; Molecular Conformation; Norfloxacin; Pentachlorophenol; Protein Multimerization; Structure-Activity Relationship; Tandem Mass Spectrometry; Tolnaftate | 2020 |
Modeling of Adhesion in Tablet Compression at the Molecular Level Using Thermal Analysis and Molecular Simulations.
Topics: Adhesiveness; Calorimetry, Differential Scanning; Compressive Strength; Flurbiprofen; Ibuprofen; Ketoprofen; Models, Molecular; Tablets | 2022 |
Disposable stochastic sensors for fast analysis of ibuprofen, ketoprofen, and flurbiprofen in their topical pharmaceutical formulations.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbon; Copper; Drug Compounding; Flurbiprofen; Ibuprofen; Ketoprofen | 2022 |
An Evolving Role of Aqueous Piperazine to Improve the Solubility of Non-Steroidal Anti-Inflammatory Drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Piperazine; Powders; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Sulindac; Water; X-Ray Diffraction | 2022 |