ketoprofen and fluorouracil

ketoprofen has been researched along with fluorouracil in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (60.00)29.6817
2010's7 (35.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Bian, J; Hu, M; Jiang, F; Li, X; Sun, H; Wu, Y; Yang, L; You, Q; Zhang, X1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ding, F; Gao, Y; He, X; Lei, Y; Li, S; Li, X; Li, Y; Li, Z; Wen, D; Zhang, Y; Zhong, M1
Iwaki, M; Ogiso, T; Okajima, K; Shiraki, T; Tanino, T; Wada, T1
Berardi, R; Carle, F; Cascinu, S; Cellerino, R; Pietroselli, D; Piga, A; Pulita, F; Romagnoli, E1
Ishihara, K; Kimura, M; Takai, M1
Fang, L; He, Z; Xu, Y; Zhao, L; Zhao, Y1
Fang, L; He, Z; Liu, S; Xu, Y; Zhao, L; Zhao, Y1

Reviews

1 review(s) available for ketoprofen and fluorouracil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

19 other study(ies) available for ketoprofen and fluorouracil

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Novel natural-product-like caged xanthones with improved druglike properties and in vivo antitumor potency.
    Bioorganic & medicinal chemistry letters, 2015, Jun-15, Volume: 25, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Products; Body Weight; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Drug Screening Assays, Antitumor; Garcinia; Humans; Mice; Structure-Activity Relationship; Transplantation, Heterologous; Xanthones

2015
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Synthesis and biological evaluation of organoselenium (NSAIDs-SeCN and SeCF
    European journal of medicinal chemistry, 2020, Dec-15, Volume: 208

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; DNA; DNA Damage; Drug Screening Assays, Antitumor; Free Radical Scavengers; Humans; Interleukin-2; Molecular Docking Simulation; Organoselenium Compounds; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Thioredoxin Reductase 1

2020
Transfollicular drug delivery: penetration of drugs through human scalp skin and comparison of penetration between scalp and abdominal skins in vitro.
    Journal of drug targeting, 2002, Volume: 10, Issue:5

    Topics: Abdomen; Acyclovir; Administration, Cutaneous; Adult; Drug Delivery Systems; Female; Fluorouracil; Hair Follicle; Humans; In Vitro Techniques; Ketoprofen; Male; Melatonin; Middle Aged; Scalp; Skin Absorption

2002
Effective prevention of 5-fluorouracil-induced superficial phlebitis by ketoprofen lysine salt gel.
    The American journal of medicine, 2003, Oct-01, Volume: 115, Issue:5

    Topics: Administration, Topical; Aged; Antimetabolites, Antineoplastic; Arm; Female; Fluorouracil; Humans; Infusions, Intravenous; Ketoprofen; Lysine; Male; Thrombophlebitis

2003
Biocompatibility and drug release behavior of spontaneously formed phospholipid polymer hydrogels.
    Journal of biomedical materials research. Part A, 2007, Volume: 80, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Antimetabolites; Biocompatible Materials; Delayed-Action Preparations; Doxorubicin; Fluorouracil; Humans; Hydrogels; Indomethacin; Ketoprofen; Male; Materials Testing; Methacrylates; Phosphorylcholine; Rats; Rats, Sprague-Dawley

2007
Effect of O-acylmenthol on transdermal delivery of drugs with different lipophilicity.
    International journal of pharmaceutics, 2008, Mar-20, Volume: 352, Issue:1-2

    Topics: Acids, Carbocyclic; Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Cinnamates; Diffusion Chambers, Culture; Drug Compounding; Fluorouracil; Hydrolysis; Indomethacin; Isosorbide Dinitrate; Ketoprofen; Kinetics; Lactates; Lidocaine; Male; Menthol; Oleic Acids; Permeability; Pharmaceutical Preparations; Rats; Rats, Wistar; Salicylates; Skin; Skin Absorption; Technology, Pharmaceutical

2008
Transdermal delivery of penetrants with differing lipophilicities using O-acylmenthol derivatives as penetration enhancers.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 69, Issue:1

    Topics: Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Fatty Acids; Fluorouracil; Indomethacin; Isosorbide Dinitrate; Ketoprofen; Lidocaine; Male; Menthol; Rats; Rats, Wistar; Skin Absorption; Technology, Pharmaceutical

2008