ketoprofen and etodolac

ketoprofen has been researched along with etodolac in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's4 (15.38)18.2507
2000's13 (50.00)29.6817
2010's8 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Cihlar, T; Ho, ES; Mulato, AS1
Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM1
Brozic, P; Gobec, S; Rizner, TL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Anderluh, M; Brunskole, M; Gobec, S; Lanisnik Rizner, T; Stefane, B; Stojan, J; Zorko, K1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Kumar, M; Sinha, VR; Thareja, S1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
de Pouvourville, G1
Chang, JY; Elwell, JM; Goldring, MB; Sohbat, E1
Anderson, SA; Brater, DC; Brown-Cartwright, D; Toto, RD1
Dainaka, J; Hashii, H; Inoue, K; Kimura, K; Motonaga, A; Nishimura, T; Ueda, F; Yamate, K1
Franchimont, P; Reginster, JY1
Heydel, JM; Humbert, AC; Li, X; Little, JM; Magdalou, J; Radominska-Pandya, A; Sabolovic, N1
Basílio, AC; Brandão, CV; Luna, SP; Machado, LP; Moutinho, FQ; Steagall, PV; Takahira, RK1
Jin, YX; Tang, YH; Zeng, S1
Au, AL; Chan, SW; Kwan, YW; Lee, SM; Leung, GP; Li, RW; Seto, SW; Tse, CM1
Hardikar, MS1
Borer, L; Jung, M; King, JN; Lees, P; Rudaz, C; Seewald, W1
Borges, M; Chaves, MP; Guimarães-Okamoto, PT; Laposy, CB; Marini Filho, R; Melchert, A; Vieira, AN1
Alshana, U; Hassan, M1

Reviews

3 review(s) available for ketoprofen and etodolac

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Piroxicam-beta-cyclodextrin in the treatment of acute pain of rheumatic disease.
    European journal of rheumatology and inflammation, 1993, Volume: 12, Issue:4

    Topics: Acute Disease; Adult; beta-Cyclodextrins; Controlled Clinical Trials as Topic; Cyclodextrins; Diclofenac; Dipyrone; Drug Combinations; Etodolac; Humans; Ketoprofen; Middle Aged; Pain; Piroxicam; Rheumatic Diseases

1993
Chiral non-steroidal anti-inflammatory drugs--a review.
    Journal of the Indian Medical Association, 2008, Volume: 106, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Etodolac; Humans; Ibuprofen; Ketoprofen; Tromethamine

2008

Trials

1 trial(s) available for ketoprofen and etodolac

ArticleYear
Evaluation of adverse effects of long-term oral administration of carprofen, etodolac, flunixin meglumine, ketoprofen, and meloxicam in dogs.
    American journal of veterinary research, 2007, Volume: 68, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Coagulation; Carbazoles; Clonixin; Dog Diseases; Dogs; Etodolac; Female; Ketoprofen; Meloxicam; Stomach Diseases; Thiazines; Thiazoles; Time Factors

2007

Other Studies

22 other study(ies) available for ketoprofen and etodolac

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1

    Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship

2000
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
    Journal of medicinal chemistry, 2004, Sep-23, Volume: 47, Issue:20

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship

2004
Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.
    Bioorganic & medicinal chemistry letters, 2005, Dec-01, Volume: 15, Issue:23

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Molecular Structure; Tumor Cells, Cultured

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Amino Acid Sequence; Ascomycota; Benzopyrans; Enzyme Inhibitors; Fungal Proteins; Melanins; Models, Molecular; Molecular Sequence Data; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Structural Homology, Protein; Substrate Specificity

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
The economic consequences of NSAID-induced gastropathy: the French context.
    Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96

    Topics: Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Cost of Illness; Diclofenac; Duodenal Ulcer; Economics, Hospital; Etodolac; France; Gastrointestinal Diseases; Humans; Ketoprofen; Naproxen; National Health Programs; Piroxicam; Rheumatic Diseases; Sulindac

1992
Etodolac preserves cartilage-specific phenotype in human chondrocytes: effects on type II collagen synthesis and associated mRNA levels.
    European journal of rheumatology and inflammation, 1990, Volume: 10, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cartilage; Cells, Cultured; Collagen; Dinoprostone; Etodolac; Fibronectins; Humans; Indoleacetic Acids; Indomethacin; Ketoprofen; Phenotype; Procollagen; RNA, Messenger; Time Factors

1990
Effects of nonsteroidal antiinflammatory drugs on renal function in patients with renal insufficiency and in cirrhotics.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1986, Volume: 8, Issue:5

    Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Dinoprostone; Etodolac; Humans; Indomethacin; Ketoprofen; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Liver Cirrhosis, Alcoholic; Prostaglandins E; Sulindac

1986
Effect of etodolac on prostaglandin E2 biosynthesis, active oxygen generation and bradykinin formation.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:6

    Topics: Animals; Aspirin; Bradykinin; Bromelains; Cartilage, Articular; Cell Line; Concanavalin A; Depression, Chemical; Diclofenac; Dinoprostone; Dogs; Etodolac; Gastric Mucosa; Guinea Pigs; Indomethacin; Interleukin-1; Ketoprofen; Kidney; Naproxen; Oxygen; Pain; Piroxicam; Rabbits; Rats

1994
Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract.
    Biochimica et biophysica acta, 2004, Nov-18, Volume: 1675, Issue:1-3

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Etodolac; Gastrointestinal Tract; Gene Expression Regulation, Enzymologic; Glucuronides; Glucuronosyltransferase; Humans; Ketoprofen; Microsomes; Naproxen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2004
Analysis of flurbiprofen, ketoprofen and etodolac enantiomers by pre-column derivatization RP-HPLC and application to drug-protein binding in human plasma.
    Journal of pharmaceutical and biomedical analysis, 2008, Apr-14, Volume: 46, Issue:5

    Topics: Acetonitriles; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Buffers; Chromatography, High Pressure Liquid; Ethylamines; Ethyldimethylaminopropyl Carbodiimide; Etodolac; Flurbiprofen; Humans; Hydrogen-Ion Concentration; Ketoprofen; Naphthalenes; Protein Binding; Reproducibility of Results; Solvents; Stereoisomerism; Sulfur Oxides; Triazoles

2008
Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells.
    European journal of pharmacology, 2009, Jun-10, Volume: 612, Issue:1-3

    Topics: Adenosine; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Cell Proliferation; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Etodolac; Humans; Indomethacin; Inhibitory Concentration 50; Ketoprofen; Kinetics; Mefenamic Acid; Muscle, Smooth, Vascular; Piroxicam; Sulindac; Temperature; Tetrazolium Salts; Thiazoles; Thioinosine

2009
In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study.
    Research in veterinary science, 2010, Volume: 88, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Etodolac; Isoenzymes; Ketoprofen; Kinetics; Lipopolysaccharides; Meloxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thiazines; Thiazoles; Thromboxane B2

2010
Nonsteroidal anti-inflammatory therapy: changes on renal function of healthy dogs.
    Acta cirurgica brasileira, 2013, Volume: 28, Issue:12

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Cyclooxygenase Inhibitors; Dogs; Etodolac; Female; gamma-Glutamyltransferase; Ketoprofen; Kidney; Meloxicam; Potassium; Sodium; Sulfonamides; Thiazines; Thiazoles; Time Factors; Treatment Outcome

2013
Switchable-hydrophilicity solvent liquid-liquid microextraction of non-steroidal anti-inflammatory drugs from biological fluids prior to HPLC-DAD determination.
    Journal of pharmaceutical and biomedical analysis, 2019, Sep-10, Volume: 174

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Centrifugation; Chromatography, High Pressure Liquid; Etodolac; Flurbiprofen; Humans; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Ketoprofen; Linear Models; Liquid Phase Microextraction; Milk, Human; Organic Chemicals; Reproducibility of Results; Saliva; Sodium Hydroxide; Solvents

2019