ketoprofen and dinoprostone

ketoprofen has been researched along with dinoprostone in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19908 (10.53)18.7374
1990's29 (38.16)18.2507
2000's23 (30.26)29.6817
2010's14 (18.42)24.3611
2020's2 (2.63)2.80

Authors

AuthorsStudies
Apiwattanakul, N; Cha, SH; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Tsuda, M1
Duffy, EM; Jorgensen, WL1
Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N1
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM1
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Hillhouse, EW; Milton, AS; Milton, NG2
Abbate, R; Arata, L; Bonechi, F; Castellani, S; Dagianti, A; Fedele, F; Gensini, GF; Iacoboni, C; Neri Serneri, GG; Prisco, D1
Fritz, ME; Green, MD; Mayambala, CS; Odle, BM; Offenbacher, S; Sena, FJ; Smith, MA; van Dyke, TE; Yeh, KC1
Chang, JY; Elwell, JM; Goldring, MB; Sohbat, E1
Abul, H; Davidson, J; Kozak, W; Milton, AS; Rotondo, D1
Anderson, SA; Brater, DC; Brown-Cartwright, D; Toto, RD1
Abul, HT; Davidson, J; Milton, AS; Rotondo, D2
Brizuela, NY; Meirovich, C; Montrull, HL; Rubio, A1
Bird, J; Giroud, JP; Tissot, M1
Barkay, J; Ben-Ezra, S; Gordon, S; Harpaz-Kerpel, S; Zuckerman, H1
Gerstenberg, T; Hald, T; Klarskov, P1
Okpako, DT; Taiwo, YO1
Chanaud, B; Chancerelle, Y; De Sousa, M; Florentin, I; Giroud, JP; Kergonou, JF; Masson, I; Mathieu, J; Strazlko, S1
Dainaka, J; Hashii, H; Inoue, K; Kimura, K; Motonaga, A; Nishimura, T; Ueda, F; Yamate, K1
Landoni, MF; Lees, P3
Cunningham, FM; Landoni, MF; Lees, P2
Cipollone, F; Cuccurullo, F; di Giamberardino, M; Greco, A; Padovano, R; Panara, MR; Patrono, C; Rotondo, MT; Santini, G; Sciulli, MG1
Itoh, K; Nakao, M; Shichijo, S; Tanaka, H; Tsuboi, I1
Kamerling, SG; Keowen, ML; Owens, JG; Prescott-Mathews, JS; Stanton, SR1
Alfano, MC; Collins, JG; Jeffcoat, MK; Li, KL; Offenbacher, S; Smith, MA; Vogel, R1
Järvinen, TA; Järvinen, TL; Moilanen, E; Moilanen, T1
Foot, R; Frean, S; Landoni, MF; Lees, P1
Martinez, J; Moreno, JJ; Sanchez, T1
Ando, T; Himeno, M; Kataoka, M; Sugimoto, K; Tobetto, K; Yamamoto, Y1
Doi, T; Ito, A; Kido, H; Kimura, K; Kodera, N; Murakami, N; Naruse, T1
Davidson, J; Guy, K; Kerr, A; Rotondo, D1
Catalioto, RM; Criscuoli, M; Cucchi, P; Lecci, A; Maggi, CA; Meini, S1
Asti, C; Bertini, R; Caselli, G; Ghezzi, P; Marullo, A; Meazza, C; Melillo, G; Pellegrini, L; Porzio, S; Sabbatini, V; Sacco, S1
Coghe, J; Deby-Dupont, G; Lekeux, P; Uystepruyst, C; Van de Weerdt, ML1
Moreno, JJ; Sánchez, T1
Harmon, FA; Rakestraw, PC; Snyder, JR; Van Hoogmoed, L1
Anglarilli, G; Bidal, D; Comas, W; Landoni, MF; Lees, P; Mucci, N1
Catalioto, RM; Lecci, A; Maggi, CA; Tramontana, M1
Benn, SJ; Conlon, P; Kay-Mugford, P; LaMarre, J1
Allegretti, M; Bertini, R; Biordi, L; Caselli, G; Martinotti, S; Marullo, A; Mascagni, P; Sabbatini, V1
Agnello, D; Bertini, R; Caselli, G; Ghezzi, P; Marullo, A; Sacco, S1
Annett, M; Binder, TA; Friedman, M; Lawrence, HP; McCombs, GB; Offenbacher, S; Paquette, DW; Smith, PC; Troullos, E; Wilder, R1
Bertone, AL; Hardy, J; Moses, VS; Weisbrode, SE1
Arifah, AK; Frean, SP; Landoni, MF; Lees, P1
Andrzejak, R; Skoczyńska, A; Wróbel, J1
Burlet, A; Camaeti, V; de Talancé, N; Devaux, Y; Grosjean, S; Longrois, D; Meistelman, C; Mertes, PM; Seguin, C; Zannad, F1
Amann, R; Ates, M; Brune, K; Gühring, H; Peskar, BA; Sommerauer, M1
Alarcón de la Lastra, C; Cabré, F; Herrerías, JM; Martín, MJ; Motilva, V; Nieto, A1
Arifah, AK; Landoni, MF; Lees, P1
Drake, CM; Snyder, JR; Van Hoogmoed, LM1
Avondo, S; Cardile, V; Garufi, F; Gentile, B; Panico, AM; Ronsisvalle, S1
Alique, M; Hornedo, JP; Lucio-Cazana, J; Parra, T; Reyes-Martin, P1
Kikuchi, S; Konno, S; Sekiguchi, M; Shirasaka, M1
Akiyama, K; Atarashi, K; Kabashima, K; Tokura, Y1
Atarashi, K; Kabashima, K; Kuma, H; Mori, T; Tokura, Y; Yoshiki, R1
Borer, L; Jung, M; King, JN; Lees, P; Rudaz, C; Seewald, W1
Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX1
Beyaert, R; Croubels, S; de Backer, P; de Baere, S; de Boever, S; Meyer, E; Neirinckx, EA1
Ahmad, W; Chanderashekara, HH; Prawez, S; Sankar, P; Sarkar, SN; Tandan, SK1
Antunes, CA; Benjamim, CF; Bozza, MT; Brogliato, AR; Canetti, C; Carvalho, RS; Kunkel, SL; Monteiro, AP; Peters-Golden, M; Tinoco, RF; Vianna-Jorge, R1
Anneken, JH; Collins, SA; Cunningham, JI; Gudelsky, GA; Yamamoto, BK1
Baldelli, F; Cipriani, S; D'Amore, C; Distrutti, E; Fiorucci, S; Francisci, D; Mencarelli, A; Renga, B; Santucci, L1
Cardenas, R; Fernandez, AC; Guevara, C; Suarez-Roca, H1
Croubels, S; De Backer, P; De Baere, S; Devreese, M; Meyer, E; Plessers, E; Schauvliege, S; van Bergen, T; Watteyn, A; Wyns, H1
Croubels, S; De Backer, P; De Baere, S; Pardon, B; Plessers, E; Sys, SU; Watteyn, A; Wyns, H1
Fukumoto, A; Hori, M; Kaku, S; Matsumoto, H; Tajima, K; Toda, Y1
Bruckmaier, RM; Dan, D; Wellnitz, O1
Almond, GW; Baynes, RE; Carlson, AR; Hernandez, L; Messenger, KM; Nixon, E; Routh, PA1
Baynes, RE; Chittenden, JT; Messenger, KM; Nixon, E1

Trials

10 trial(s) available for ketoprofen and dinoprostone

ArticleYear
[Prostaglandins in primary dysmenorrhea. Effect of ketoprofen].
    Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina), 1987, Volume: 45, Issue:1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Dysmenorrhea; Female; Humans; Ketoprofen; Phenylpropionates; Prostaglandins E; Prostaglandins F

1987
The prostaglandin inhibitor effect of antiinflammatory drugs in the therapy of male infertility.
    Fertility and sterility, 1984, Volume: 42, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Cyclic AMP; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Humans; Indomethacin; Ketoprofen; Luteinizing Hormone; Male; Oligospermia; Prostaglandin Antagonists; Prostaglandins E; Prostaglandins F; Semen; Sperm Count; Sperm Motility; Testosterone

1984
Comparative pharmacodynamics of flunixin, ketoprofen and tolfenamic acid in calves.
    The Veterinary record, 1995, Oct-21, Volume: 137, Issue:17

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Clonixin; Cross-Over Studies; Dinoprostone; Edema; Glucuronidase; Ketoprofen; Neutrophils; ortho-Aminobenzoates; Superoxides; Thromboxane B2

1995
Pharmacokinetics and pharmacodynamics of ketoprofen in calves applying PK/PD modelling.
    Journal of veterinary pharmacology and therapeutics, 1995, Volume: 18, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Carrageenan; Cattle; Cattle Diseases; Cross-Over Studies; Diffusion Chambers, Culture; Dinoprostone; Dose-Response Relationship, Drug; Edema; Glucuronidase; Half-Life; Inflammation; Injections, Intravenous; Ketoprofen; Leukotriene B4; Male; Stereoisomerism; Thromboxane B2

1995
Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses.
    American journal of veterinary research, 1996, Volume: 57, Issue:6

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Horse Diseases; Horses; Joints; Ketoprofen; Lameness, Animal; Leukotriene B4; Male; Phenylbutazone; Proteins; Synovial Fluid; Synovitis

1996
Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in the horse.
    Journal of veterinary pharmacology and therapeutics, 1996, Volume: 19, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Cross-Over Studies; Dinoprostone; Dose-Response Relationship, Drug; Edema; Extracellular Space; Glucuronidase; Horses; Injections, Intravenous; Ketoprofen; Male; Prostaglandin-Endoperoxide Synthases; Regression Analysis; Software; Stereoisomerism; Thromboxane B2

1996
Ketoprofen and phenylbutazone attenuation of PAF-induced lung inflammation in calves.
    Veterinary journal (London, England : 1997), 1999, Volume: 157, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Dinoprostone; Ketoprofen; Leukotriene B4; Male; Phenylbutazone; Placebos; Platelet Activating Factor; Pneumonia; Respiration; Thromboxane B2

1999
Pharmacodynamic effects of ketoprofen on crevicular fluid prostanoids in adult periodontitis.
    Journal of clinical periodontology, 2000, Volume: 27, Issue:8

    Topics: Administration, Topical; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chi-Square Distribution; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gingival Crevicular Fluid; Humans; Immunity, Cellular; Ketoprofen; Leukotriene B4; Male; Middle Aged; Periodontitis; Prostaglandins; Statistics, Nonparametric

2000
Modulation by gamithromycin and ketoprofen of in vitro and in vivo porcine lipopolysaccharide-induced inflammation.
    Veterinary immunology and immunopathology, 2015, Dec-15, Volume: 168, Issue:3-4

    Topics: Acute-Phase Proteins; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cytokines; Dinoprostone; Drug Therapy, Combination; Gene Expression Regulation; Inflammation; Ketoprofen; Leukocytes, Mononuclear; Lipopolysaccharides; Macrolides; Male; Swine; Swine Diseases

2015
Immunomodulatory properties of gamithromycin and ketoprofen in lipopolysaccharide-challenged calves with emphasis on the acute-phase response.
    Veterinary immunology and immunopathology, 2016, Volume: 171

    Topics: Acute-Phase Reaction; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Dinoprostone; Drug Synergism; Drug Therapy, Combination; Immunologic Factors; Ketoprofen; Lipopolysaccharides; Macrolides; Male; Serum Amyloid A Protein; Tumor Necrosis Factor-alpha

2016

Other Studies

66 other study(ies) available for ketoprofen and dinoprostone

ArticleYear
Identification of multispecific organic anion transporter 2 expressed predominantly in the liver.
    FEBS letters, 1998, Jun-12, Volume: 429, Issue:2

    Topics: Animals; Blotting, Northern; Carrier Proteins; Ion Transport; Liver; Membrane Proteins; Organic Anion Transporters, Sodium-Independent; Rats; Salicylates; Salicylic Acid; Substrate Specificity; Xenopus laevis

1998
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Aug-05, Volume: 100, Issue:16

    Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors

2003
Molecular characteristics for solid-state limited solubility.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility

2008
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Activation of the hypothalamo-pituitary-adrenocortical axis in the conscious rabbit by the pyrogen polyinosinic:polycytidylic acid is dependent on corticotrophin-releasing factor-41.
    The Journal of endocrinology, 1992, Volume: 135, Issue:1

    Topics: Animals; Body Temperature; Corticotropin-Releasing Hormone; Dinoprostone; Hydrocortisone; Hypothalamo-Hypophyseal System; Ketoprofen; Male; Pituitary-Adrenal System; Poly I-C; Poly U; Pyrogens; Rabbits; Stimulation, Chemical

1992
Physiologic role of coronary PGI2 and PGE2 in modulating coronary vascular response to sympathetic stimulation.
    American heart journal, 1990, Volume: 119, Issue:4

    Topics: Adult; Aspirin; Cold Temperature; Coronary Circulation; Coronary Vessels; Dinoprostone; Epoprostenol; Female; Humans; Ketoprofen; Male; Sympathetic Nervous System; Vascular Resistance; Vasodilation

1990
Inhibition of human periodontal prostaglandin E2 synthesis with selected agents.
    Agents and actions, 1990, Volume: 29, Issue:3-4

    Topics: Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Eicosapentaenoic Acid; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Meclofenamic Acid; Naproxen; Periodontitis; Periodontium; Vitamin E

1990
Etodolac preserves cartilage-specific phenotype in human chondrocytes: effects on type II collagen synthesis and associated mRNA levels.
    European journal of rheumatology and inflammation, 1990, Volume: 10, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cartilage; Cells, Cultured; Collagen; Dinoprostone; Etodolac; Fibronectins; Humans; Indoleacetic Acids; Indomethacin; Ketoprofen; Phenotype; Procollagen; RNA, Messenger; Time Factors

1990
Lipopolysaccharide, muramyl dipeptide and polyinosinic: polycytidylic acid induce the accumulation of inositol phosphates in blood monocytes and lymphocytes.
    Cellular signalling, 1989, Volume: 1, Issue:4

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Anisomycin; Cells, Cultured; Dinoprostone; Egtazic Acid; Inositol Phosphates; Ketoprofen; Kinetics; Lipopolysaccharides; Lymphocytes; Macrophages; Poly I-C; Rabbits

1989
Effects of nonsteroidal antiinflammatory drugs on renal function in patients with renal insufficiency and in cirrhotics.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1986, Volume: 8, Issue:5

    Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Dinoprostone; Etodolac; Humans; Indomethacin; Ketoprofen; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Liver Cirrhosis, Alcoholic; Prostaglandins E; Sulindac

1986
Pyrogenic immunomodulators increase the level of prostaglandin E2 in the blood simultaneously with the onset of fever.
    European journal of pharmacology, 1988, Sep-13, Volume: 154, Issue:2

    Topics: Animals; Body Temperature; Dinoprostone; Fever; Interleukin-1; Ketoprofen; Lipopolysaccharides; Male; Poly I-C; Pyrogens; Rabbits; Radioimmunoassay; Time Factors

1988
The modulation of peritoneal macrophage chemiluminescence by acute pleural inflammation, prostanoids and cyclo/lipoxygenase inhibitors.
    Agents and actions, 1985, Volume: 17, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acute Disease; Animals; Catechols; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Indomethacin; Ketoprofen; Lipoxygenase Inhibitors; Luminescent Measurements; Macrophages; Male; Masoprocol; Peritoneal Cavity; Pleurisy; Prostaglandins; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains

1985
Vasoactive intestinal polypeptide influence on lower urinary tract smooth muscle from human and pig.
    The Journal of urology, 1984, Volume: 131, Issue:5

    Topics: Animals; Carbachol; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Ketoprofen; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propranolol; Prostaglandins E; Prostaglandins F; Substance P; Swine; Tetrodotoxin; Urethra; Urinary Bladder; Vasoactive Intestinal Peptide

1984
Cyclo-oxygenase inhibitors antagonize indirectly evoked contractions of the guinea-pig isolated ileum by inhibiting acetylcholine release.
    British journal of pharmacology, 1984, Volume: 82, Issue:3

    Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Ketoprofen; Male; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Nicotine; Prostaglandins E; Synaptic Membranes

1984
Restoration of postburn impaired lymphocyte responsiveness by nonsteroidal anti-inflammatory drugs is independent of prostaglandin E2 inhibition.
    Journal of leukocyte biology, 1994, Volume: 55, Issue:1

    Topics: Administration, Oral; Amino Acid Oxidoreductases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Dinoprostone; Indomethacin; Ketoprofen; Lymphocyte Activation; Male; Niflumic Acid; Nitric Oxide Synthase; Piroxicam; Rats; Rats, Wistar; Salicylates

1994
Effect of etodolac on prostaglandin E2 biosynthesis, active oxygen generation and bradykinin formation.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:6

    Topics: Animals; Aspirin; Bradykinin; Bromelains; Cartilage, Articular; Cell Line; Concanavalin A; Depression, Chemical; Diclofenac; Dinoprostone; Dogs; Etodolac; Gastric Mucosa; Guinea Pigs; Indomethacin; Interleukin-1; Ketoprofen; Kidney; Naproxen; Oxygen; Pain; Piroxicam; Rabbits; Rats

1994
Modulation of the prostaglandin responses of conscious rabbits to the pyrogen polyinosinic:polycytidylic acid by corticotrophin-releasing factor-41.
    The Journal of endocrinology, 1993, Volume: 138, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Corticotropin-Releasing Hormone; Dinoprost; Dinoprostone; Ketoprofen; Male; Peptide Fragments; Poly I-C; Prostaglandins; Rabbits; Receptors, Corticotropin-Releasing Hormone; Temperature; Time Factors

1993
Comparison of the anti-inflammatory actions of flunixin and ketoprofen in horses applying PK/PD modelling.
    Equine veterinary journal, 1995, Volume: 27, Issue:4

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Clonixin; Cross-Over Studies; Dinoprostone; Exudates and Transudates; Glucuronidase; Half-Life; Horses; Inflammation; Ketoprofen; Leukotriene B4; Male; Models, Biological; Thromboxane B2

1995
Effects of the novel anti-inflammatory compounds, N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulphonamide (NS-398) and 5-methanesulphonamido-6-(2,4-difluorothio-phenyl)-1-inda none (L-745,337), on the cyclo-oxygenase activity of human blood prostaglandin
    British journal of pharmacology, 1995, Volume: 116, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Blotting, Western; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Induction; Female; Humans; In Vitro Techniques; Indans; Ketoprofen; Male; Middle Aged; Monocytes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Binding; Stereoisomerism; Sulfonamides; Thromboxane B2

1995
Nonsteroidal anti-inflammatory drugs differentially regulate cytokine production in human lymphocytes: up-regulation of TNF, IFN-gamma and IL-2, in contrast to down-regulation of IL-6 production.
    Cytokine, 1995, Volume: 7, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Cells, Cultured; Clone Cells; Diclofenac; Dinoprostone; Gene Expression Regulation; HTLV-I Infections; Humans; Indomethacin; Interferon-gamma; Interleukin-2; Interleukin-6; Ketoprofen; Leukemia-Lymphoma, Adult T-Cell; Leukocytes, Mononuclear; Lymphocyte Activation; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger; Sarcoidosis, Pulmonary; T-Lymphocyte Subsets; Th1 Cells; Th2 Cells; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Uveitis

1995
Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in calves.
    Chirality, 1995, Volume: 7, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Chromatography, High Pressure Liquid; Diffusion Chambers, Culture; Dinoprostone; Exudates and Transudates; Half-Life; Inflammation; Injections, Intravenous; Interleukin-6; Ketoprofen; Male; Stereoisomerism; Thromboxane B2; Tumor Necrosis Factor-alpha

1995
The effect of ketoprofen creams on periodontal disease in rhesus monkeys.
    Journal of periodontal research, 1996, Volume: 31, Issue:8

    Topics: Administration, Topical; Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dental Plaque; Dinoprostone; Double-Blind Method; Edema; Emollients; Female; Follow-Up Studies; Gingival Crevicular Fluid; Gingival Hemorrhage; Gingivitis; Interleukin-1; Ketoprofen; Leukotriene B4; Macaca mulatta; Male; Molar; Periodontal Attachment Loss; Periodontitis; Placebos; Radiographic Image Enhancement; Random Allocation; Subtraction Technique; Thromboxane B2; Tumor Necrosis Factor-alpha; Vitamin E

1996
Endogenous nitric oxide and prostaglandin E2 do not regulate the synthesis of each other in interleukin-1 beta-stimulated rat articular cartilage.
    Inflammation, 1996, Volume: 20, Issue:6

    Topics: Animals; Aspirin; Cartilage, Articular; Dexamethasone; Dinoprostone; Electron Transport Complex IV; Interleukin-1; Ketoprofen; Kinetics; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Organ Culture Techniques; Ornithine; Prostaglandin Antagonists; Rats; Rats, Wistar; Triazoles

1996
Effects of flunixin, tolfenamic acid, R(-) and S(+) ketoprofen on the response of equine synoviocytes to lipopolysaccharide stimulation.
    Equine veterinary journal, 1996, Volume: 28, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Clonixin; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Glucuronidase; Horses; Interleukin-1; Interleukin-6; Ketoprofen; Lipopolysaccharides; ortho-Aminobenzoates; Synovial Membrane; Tumor Necrosis Factor-alpha

1996
Role of prostaglandin H synthase-2-mediated conversion of arachidonic acid in controlling 3T6 fibroblast growth.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: 3T3 Cells; Animals; Arachidonic Acid; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; DNA; Indans; Isoenzymes; Ketoprofen; Kinetics; Mice; Prostaglandin-Endoperoxide Synthases

1997
The effects of a newly developed nonsteroidal anti-inflammatory drug (M-5011) on arachidonic acid metabolism in rheumatoid synovial fibroblasts.
    Japanese journal of pharmacology, 1997, Volume: 75, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Rheumatoid; Bradykinin; Carbon Radioisotopes; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Female; Fibroblasts; Humans; Indomethacin; Interleukin-1; Isoenzymes; Ketoprofen; Membrane Proteins; Middle Aged; Phenylpropionates; Prostaglandin-Endoperoxide Synthases; Synovial Membrane

1997
Anti-inflammatory, analgesic and anti-pyretic effects of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a new non-steroidal anti-inflammatory drug, in rats and guinea pigs.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Diclofenac; Dinoprostone; Edema; Erythema; Fever; Gastric Mucosa; Guinea Pigs; Hindlimb; Hyperalgesia; Indomethacin; Intestinal Mucosa; Ketoprofen; Male; Phenylpropionates; Rats; Species Specificity; Stomach Ulcer; Ultraviolet Rays

1998
Prostaglandin and fatty acid modulation of Escherichia coli O157 phagocytosis by human monocytic cells.
    Immunology, 1998, Volume: 94, Issue:2

    Topics: Cell Culture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Immunologic; Escherichia coli O157; Fatty Acids; Fluorescein-5-isothiocyanate; Humans; Interleukin-1; Ketoprofen; Lipopolysaccharides; Monocytes; Phagocytosis; Tumor Cells, Cultured

1998
Inflammation modifies the role of cyclooxygenases in the contractile responses of the rat detrusor smooth muscle to kinin agonists.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: Animals; Bradykinin; Cystitis; Dinoprostone; In Vitro Techniques; Ketoprofen; Male; Muscle Contraction; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Sulfonamides; Urinary Bladder

1998
Differential contribution of R and S isomers in ketoprofen anti-inflammatory activity: role of cytokine modulation.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cytokines; Dinoprostone; Edema; Guinea Pigs; Hyperalgesia; Ketoprofen; Lipopolysaccharides; Male; Stereoisomerism; Tumor Necrosis Factor-alpha

1998
Ketoprofen S(+) enantiomer inhibits prostaglandin production and cell growth in 3T6 fibroblast cultures.
    European journal of pharmacology, 1999, Apr-01, Volume: 370, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cell Survival; Cells, Cultured; Dinoprostone; DNA; Fibroblasts; Ketoprofen; Mice; Stereoisomerism; Thymidine

1999
In vitro effects of nonsteroidal anti-inflammatory agents and prostaglandins I2, E2, and F2alpha on contractility of taenia of the large colon of horses.
    American journal of veterinary research, 1999, Volume: 60, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Clonixin; Colon; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Epoprostenol; Horses; Indomethacin; Ketoprofen; Muscle Contraction; Muscle, Smooth; Phenylbutazone; Prostaglandins

1999
Enantiospecific pharmacokinetics and pharmacodynamics of ketoprofen in sheep.
    Journal of veterinary pharmacology and therapeutics, 1999, Volume: 22, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chemistry, Pharmaceutical; Cross-Over Studies; Dinoprostone; Exudates and Transudates; Inflammation; Injections, Intravenous; Ketoprofen; Male; Sheep; Thromboxane B2

1999
Role of prostanoids in the contraction induced by a tachykinin NK2 receptor agonist in the hamster urinary bladder.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:4

    Topics: Animals; Cricetinae; Cyclooxygenase Inhibitors; Dinoprostone; Imidazoles; In Vitro Techniques; Ketoprofen; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth; Neurokinin A; Nifedipine; Peptide Fragments; Prostaglandins; Receptors, Neurokinin-2; Stereoisomerism; Urinary Bladder

2000
In vitro effects of nonsteroidal anti-inflammatory drugs on cyclooxygenase activity in dogs.
    American journal of veterinary research, 2000, Volume: 61, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Carbazoles; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; DNA; DNA Primers; Dogs; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Gene Expression Regulation, Enzymologic; Immunoenzyme Techniques; Isoenzymes; Ketoprofen; Lipopolysaccharides; Meloxicam; ortho-Aminobenzoates; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA; Thiazines; Thiazoles

2000
R- and S-isomers of nonsteroidal anti-inflammatory drugs differentially regulate cytokine production.
    European cytokine network, 2000, Volume: 11, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dinoprostone; Female; Flurbiprofen; Ibuprofen; In Vitro Techniques; Interleukin-10; Interleukin-6; Ketoprofen; Lipopolysaccharides; Macrophages, Peritoneal; Mice; RNA, Messenger; Stereoisomerism; Tumor Necrosis Factor-alpha

2000
Lps induces IL-6 in the brain and in serum largely through TNF production.
    Cytokine, 2000, Volume: 12, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Brain; Dinoprostone; Interleukin-6; Ketoprofen; Lipopolysaccharides; Macrophages; Male; Mice; Rats; Tumor Necrosis Factor-alpha

2000
Effects of anti-inflammatory drugs on lipopolysaccharide-challenged and -unchallenged equine synovial explants.
    American journal of veterinary research, 2001, Volume: 62, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Carbazoles; Clonixin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Horses; Hyaluronic Acid; Isoenzymes; Ketoprofen; Lipopolysaccharides; Meloxicam; Methylprednisolone; Organ Culture Techniques; Phenylbutazone; Prostaglandin-Endoperoxide Synthases; Synovial Membrane; Thiazines; Thiazoles

2001
Pharmacodynamics and pharmacokinetics of ketoprofen enantiomers in sheep.
    American journal of veterinary research, 2001, Volume: 62, Issue:1

    Topics: Animals; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Female; Half-Life; Isoenzymes; Ketoprofen; Metabolic Clearance Rate; Prostaglandin-Endoperoxide Synthases; Sheep; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2

2001
Lead-cadmium interaction effect on the responsiveness of rat mesenteric vessels to norepinephrine and angiotensin II.
    Toxicology, 2001, May-21, Volume: 162, Issue:3

    Topics: Analysis of Variance; Angiotensin II; Animals; Cadmium Poisoning; Calcium; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Ketoprofen; Lead Poisoning; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; Papaverine; Potassium Chloride; Rats; Rats, Inbred BUF; Receptors, Angiotensin; Vasoconstriction; Vasoconstrictor Agents; Verapamil

2001
Cytokines and cytokine inducers stimulate prostaglandin E2 entry into the brain.
    Pflugers Archiv : European journal of physiology, 2001, Volume: 442, Issue:4

    Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Brain; Dinoprostone; Fever; Injections, Intravenous; Interferon Inducers; Interleukin-1; Iodine Radioisotopes; Ketoprofen; Lipopolysaccharides; Male; Poly I-C; Rabbits; Third Ventricle; Tumor Necrosis Factor-alpha

2001
Lipopolysaccharide-induced increase of prostaglandin E(2) is mediated by inducible nitric oxide synthase activation of the constitutive cyclooxygenase and induction of membrane-associated prostaglandin E synthase.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Oct-01, Volume: 167, Issue:7

    Topics: Animals; Cell Membrane; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Guanidines; Intramolecular Oxidoreductases; Isoenzymes; Ketoprofen; Lipopolysaccharides; Liver; Male; Membrane Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred WKY; RNA, Messenger; Sulfonamides

2001
Ketoprofen-induced cyclooxygenase inhibition in renal medulla and platelets of rats treated with caffeine.
    Pharmacology, 2001, Volume: 63, Issue:4

    Topics: Animals; Blood Platelets; Caffeine; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Gene Expression; Ketoprofen; Kidney Medulla; Male; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2001
Gastric toxicity of racemic ketoprofen and its enantiomers in rat: oxygen radical generation and COX-expression.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Female; Gastric Mucosa; Glutathione; Isoenzymes; Ketoprofen; Male; Membrane Proteins; Neutrophils; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reactive Oxygen Species; Stereoisomerism; Stomach Ulcer; Thiobarbituric Acid Reactive Substances

2002
Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat.
    Journal of veterinary pharmacology and therapeutics, 2003, Volume: 26, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Diffusion Chambers, Culture; Dinoprostone; Dose-Response Relationship, Drug; Exudates and Transudates; Goats; Injections, Intravenous; Ketoprofen; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2

2003
In vitro investigation of the effects of nonsteroidal anti-inflammatory drugs, prostaglandin E2, and prostaglandin F2alpha on contractile activity of the third compartment of the stomach of llamas.
    American journal of veterinary research, 2004, Volume: 65, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Camelids, New World; Dinoprost; Dinoprostone; In Vitro Techniques; Indomethacin; Ketoprofen; Muscle Contraction; Nabumetone; Stomach

2004
"In vitro" differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology.
    Inflammation, 2005, Volume: 29, Issue:4-6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cell Survival; Cells, Cultured; Chondrocytes; Dinoprostone; Femur Head; Flurbiprofen; Glycosaminoglycans; Humans; Interleukin-1beta; Ketoprofen; Matrix Metalloproteinase 3; Nitrites; Reactive Oxygen Species; Stereoisomerism

2005
Cyclooxygenase-independent inhibition of H2O2-induced cell death by S-ketoprofen in renal cells.
    Pharmacological research, 2007, Volume: 55, Issue:4

    Topics: Animals; Apoptosis; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Enzyme Induction; Epithelial Cells; Humans; Hydrogen Peroxide; Ketoprofen; Kidney Tubules; LLC-PK1 Cells; Mesangial Cells; Oxidants; Oxidative Stress; PPAR gamma; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Protective Agents; Rats; Stereoisomerism; Swine

2007
Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model.
    BMC musculoskeletal disorders, 2008, Jan-31, Volume: 9

    Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Contusions; Dinoprostone; Indomethacin; Inflammation; Ketoprofen; Male; Pain; Pain Threshold; Phenylacetates; Phenylpropionates; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Sprains and Strains

2008
Skin application of the nonsteroidal anti-inflammatory drug ketoprofen downmodulates the antigen-presenting ability of Langerhans cells in mice.
    The British journal of dermatology, 2008, Volume: 159, Issue:2

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen Presentation; B7-2 Antigen; Cells, Cultured; Dermatitis, Contact; Dinoprostone; Female; Histocompatibility Antigens Class II; Ketoprofen; Langerhans Cells; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Picryl Chloride; Skin

2008
Skin application of ketoprofen systemically suppresses contact hypersensitivity by inducing CD4(+) CD25(+) regulatory T cells.
    Journal of dermatological science, 2009, Volume: 53, Issue:3

    Topics: Adjuvants, Immunologic; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; CD4 Antigens; CTLA-4 Antigen; Dermatitis, Contact; Dinoprostone; Female; Forkhead Transcription Factors; Haptens; Interleukin-10; Interleukin-2 Receptor alpha Subunit; Ketoprofen; Lymph Nodes; Mice; Mice, Inbred BALB C; Oxazolone; Picryl Chloride; T-Lymphocytes, Regulatory

2009
In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study.
    Research in veterinary science, 2010, Volume: 88, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Etodolac; Isoenzymes; Ketoprofen; Kinetics; Lipopolysaccharides; Meloxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thiazines; Thiazoles; Thromboxane B2

2010
Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Dinoprostone; Disease Models, Animal; Edema; Hyperalgesia; Inflammation; Inflammation Mediators; Injections, Subcutaneous; Interleukin-1beta; Ketoprofen; Male; Nerve Block; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatic Nerve; Tumor Necrosis Factor-alpha

2010
Pharmacodynamics of tepoxalin, sodium-salicylate and ketoprofen in an intravenous lipopolysaccharide inflammation model in broiler chickens.
    Journal of veterinary pharmacology and therapeutics, 2010, Volume: 33, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Chickens; Chromatography, High Pressure Liquid; Dinoprostone; Dose-Response Relationship, Drug; Female; Flow Cytometry; Inflammation; Injections, Intravenous; Interleukin-1beta; Interleukin-6; Ketoprofen; Lipopolysaccharides; Male; Poultry Diseases; Pyrazoles; Sodium Salicylate

2010
Subacute arsenic exposure through drinking water reduces the pharmacodynamic effects of ketoprofen in male rats.
    Environmental toxicology and pharmacology, 2012, Volume: 33, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arsenites; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Water; Drug Interactions; Fever; Formaldehyde; Hindlimb; Inflammation; Inflammation Mediators; Interleukin-1beta; Ketoprofen; Lipopolysaccharides; Male; Membrane Proteins; Muscle, Skeletal; Pain; Rats; Rats, Wistar; Sodium Compounds; Time Factors; Tumor Necrosis Factor-alpha; Water Pollutants, Chemical

2012
Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2.
    Shock (Augusta, Ga.), 2012, Volume: 38, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dinoprostone; Disease Models, Animal; Immune Tolerance; Ketoprofen; Macrophages; Mice; Mice, Inbred BALB C; Phagocytosis; Receptors, Prostaglandin E, EP4 Subtype; Sepsis; Severity of Illness Index

2012
MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2013, Volume: 8, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Cell Count; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dentate Gyrus; Dinoprostone; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Immunohistochemistry; Interneurons; Ketoprofen; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Parvalbumins; Presynaptic Terminals; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Serotonin

2013
In vivo administration of ritonavir worsens intestinal damage caused by cyclooxygease inhibitors.
    European journal of pharmacology, 2014, Jan-15, Volume: 723

    Topics: Alprostadil; Animals; Apoptosis; Aspirin; Chemokine CCL2; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; HIV Protease Inhibitors; HT29 Cells; Humans; Integrin alpha1beta1; Intestinal Mucosa; Intestine, Small; Ketoprofen; Mice; Mice, Inbred C57BL; Misoprostol; Naproxen; Nitric Oxide Synthase Type II; Ritonavir; RNA, Messenger; Tumor Necrosis Factor-alpha

2014
Reduction of spinal PGE2 concentrations prevents swim stress-induced thermal hyperalgesia.
    Neuroscience letters, 2015, Mar-30, Volume: 591

    Topics: Animals; Biomarkers; Corticosterone; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Escape Reaction; Hot Temperature; Hyperalgesia; Ketoprofen; Male; Meloxicam; Rats, Sprague-Dawley; Spinal Cord; Stress, Psychological; Swimming; Thiazines; Thiazoles

2015
Analgesic effect of S (+)-flurbiprofen plaster in a rat model of knee arthritis: analysis of gait and synovial fluid prostaglandin E
    The Journal of pharmacy and pharmacology, 2018, Volume: 70, Issue:7

    Topics: Analgesics; Animals; Arthritis, Experimental; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Flurbiprofen; Gait; Ketoprofen; Male; Phenylpropionates; Rats; Synovial Fluid; Transdermal Patch

2018
Ketoprofen affects the mammary immune response in dairy cows in vivo and in vitro.
    Journal of dairy science, 2018, Volume: 101, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cell Count; Dinoprostone; Female; Immunity; Immunoglobulin G; Ketoprofen; Lipopolysaccharides; Mammary Glands, Animal; Mastitis, Bovine; Milk; RNA, Messenger

2018
Comparative effects of nonsteroidal anti-inflammatory drugs at castration and tail-docking in neonatal piglets.
    PloS one, 2021, Volume: 16, Issue:11

    Topics: Animal Husbandry; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Castration; Clonixin; Dinoprostone; Extracellular Fluid; Hydrocortisone; Ketoprofen; Male; Meloxicam; Pain; Pain Management; Swine; Tail

2021
Pharmacokinetic/pharmacodynamic modeling of ketoprofen and flunixin at piglet castration and tail-docking.
    Journal of veterinary pharmacology and therapeutics, 2022, Volume: 45, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Dinoprostone; Hydrocortisone; Ketoprofen; Male; Orchiectomy; Pain; Swine; Tail

2022