ketoprofen and diflunisal

ketoprofen has been researched along with diflunisal in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (14.71)	18.7374
1990's	4 (11.76)	18.2507
2000's	13 (38.24)	29.6817
2010's	11 (32.35)	24.3611
2020's	1 (2.94)	2.80

Authors

Authors	Studies
Andricopulo, AD; Moda, TL; Montanari, CA	1
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S	1
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Cihlar, T; Ho, ES; Mulato, AS	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM	1
Chang, TK; Ensom, MH; Kiang, TK	1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P	1
Kumar, M; Sinha, VR; Thareja, S	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Altman, RA; Borel, T; Davis, I; de Azambuja, F; Johnson, D; Liu, A; Sorrentino, JP; Udokwu, C; Yang, Y	1
Artuso, T; Bernadou, J; Meunier, B; Paillous, N	1
Duffill, MB; Taylor, BJ	1
Court, H; Volans, GN	1
Loewen, GR; Verbeeck, RK; Wallace, SM	1
Humes, JL; Kuehl, FA; Sadowski, SJ; Winter, CA	1
Dickinson, RG; Worrall, S	1
Meunier, CJ; Verbeeck, RK	1
Choi, JS; Han, HK; Jin, MJ	1
Cheng, Y; Fu, R; Man, N; Wang, X; Wen, L; Xu, T	1
Koç, FE; Senel, M	1

Reviews

4 review(s) available for ketoprofen and diflunisal

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review. The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika, 1983, Volume: 38, Issue:7 Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indomethacin; Ketoprofen; Oxyphenbutazone; Pain, Postoperative; Phenylbutazone	1983

Other Studies

30 other study(ies) available for ketoprofen and diflunisal

Article	Year
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Molecular pharmacology, 1999, Volume: 55, Issue:5 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1 Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship	2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints. Journal of medicinal chemistry, 2004, Sep-23, Volume: 47, Issue:20 Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship	2004
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions. Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21 Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence	2010
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway. Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1 Topics: Bacterial Proteins; Binding Sites; Biosynthetic Pathways; Carboxy-Lyases; Catalytic Domain; Crystallography, X-Ray; Diflunisal; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kynurenine; Molecular Docking Simulation; NAD; Pseudomonas fluorescens; Structure-Activity Relationship; Tryptophan	2021
DNA strand breaks photosensitized by benoxaprofen and other non steroidal antiinflammatory agents. Biochemical pharmacology, 1990, Feb-01, Volume: 39, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacteriophage phi X 174; Diflunisal; DNA Damage; DNA, Circular; DNA, Superhelical; DNA, Viral; Ketoprofen; Light; Molecular Structure; Naproxen; Propionates	1990
Pseudoporphyria from nonsteroidal antiinflammatory drugs. The New Zealand medical journal, 1987, May-27, Volume: 100, Issue:824 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Diflunisal; Humans; Ketoprofen; Middle Aged; Naproxen; Porphyrias; Skin Diseases; Time Factors	1987
Poisoning after overdose with non-steroidal anti-inflammatory drugs. Adverse drug reactions and acute poisoning reviews, 1984,Spring, Volume: 3, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin	1984
Reduced elimination of ketoprofen in the elderly is not necessarily due to impaired glucuronidation. British journal of clinical pharmacology, 1984, Volume: 17, Issue:6 Topics: Aged; Aging; Clofibric Acid; Diflunisal; Glucuronates; Humans; Ketoprofen; Phenylpropionates; Probenecid	1984
Multiple sites on prostaglandin cyclooxygenase are determinants in the action of nonsteroidal antiinflammatory agents. Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:4 Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Diflunisal; Indomethacin; Ketoprofen; Male; Rats; Salicylates; Stomach Ulcer; Structure-Activity Relationship	1981
Rat serum albumin modified by diflunisal acyl glucuronide is immunogenic in rats. Life sciences, 1995, Volume: 56, Issue:22 Topics: Animals; Antibody Formation; Cross Reactions; Diflunisal; Epitopes; Glucuronates; Immunoglobulin G; Ketoprofen; Male; Naproxen; Rats; Rats, Wistar; Serum Albumin	1995
Glucuronidation of R- and S-ketoprofen, acetaminophen, and diflunisal by liver microsomes of adjuvant-induced arthritic rats. Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:1 Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chromatography, High Pressure Liquid; Diflunisal; Glucuronates; Ketoprofen; Male; Microsomes, Liver; Rats; Rats, Wistar	1999
Role of monocarboxylic acid transporters in the cellular uptake of NSAIDs. The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzoic Acid; Caco-2 Cells; Carbon Radioisotopes; Diclofenac; Diflunisal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Ketoprofen; Lactic Acid; Monocarboxylic Acid Transporters; Naproxen; Permeability	2005
Transdermal delivery of nonsteroidal anti-inflammatory drugs mediated by polyamidoamine (PAMAM) dendrimers. Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:3 Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dendrimers; Diflunisal; Ketoprofen; Polyamines; Rats; Rats, Sprague-Dawley; Skin Absorption	2007
Solubility enhancement of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) using polypolypropylene oxide core PAMAM dendrimers. International journal of pharmaceutics, 2013, Jul-15, Volume: 451, Issue:1-2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Dendrimers; Diflunisal; Drug Delivery Systems; Ibuprofen; Ketoprofen; Polymers; Propylene Glycols; Solubility; Temperature	2013