ketoconazole has been researched along with vorapaxar in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alton, KB; Chowdhury, SK; Gao, L; Ghosal, A; Kishnani, NS; Lu, X; Penner, N; Ramanathan, R | 1 |
| Cutler, DL; Johnson-Levonas, AO; Kosoglou, T; Kumar, B; Schiller, JE; Statkevich, P; Xuan, F; Young, S | 1 |
1 trial(s) available for ketoconazole and vorapaxar
| Article | Year |
|---|---|
The effect of multiple doses of ketoconazole or rifampin on the single- and multiple-dose pharmacokinetics of vorapaxar.
Topics: Adult; Aged; Cytochrome P-450 CYP3A; Female; Humans; Ketoconazole; Lactones; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyridines; Rifampin; Young Adult | 2013 |
1 other study(ies) available for ketoconazole and vorapaxar
| Article | Year |
|---|---|
Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist.
Topics: Astemizole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Ketoconazole; Lactones; Microsomes; Microsomes, Liver; Pyridines; Receptor, PAR-1; Receptors, Thrombin; Recombinant Proteins; Tranylcypromine | 2011 |