ketoconazole has been researched along with triptolide in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; Guo, J; Huang, X; Jiang, Z; Liu, J; Liu, L; Wang, T; Yang, L; Zhang, L; Zhang, Y; Zhou, Z | 1 |
| Cao, RS; He, L; Ji, SG; Li, XF; Liu, J; Wu, JC; Ye, F; Zhang, N; Zhang, XF | 1 |
| Huang, X; Ji, J; Jiang, Z; Su, Y; Tai, T; Zhang, L | 1 |
| Huang, J; Li, F; Xiao, X; Zhang, T; Zhao, Q | 1 |
4 other study(ies) available for ketoconazole and triptolide
| Article | Year |
|---|---|
Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Dexamethasone; Diterpenes; Enzyme Inhibitors; Epoxy Compounds; Female; Ketoconazole; Liver; Male; Membrane Proteins; Microsomes, Liver; Phenanthrenes; Rats; Rats, Sprague-Dawley; Sex Factors | 2010 |
Effects of triptolide on the pharmacokinetics of cyclophosphamide in rats: a possible role of cytochrome P3A4 inhibition.
Topics: Animals; Cyclophosphamide; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diterpenes; Epoxy Compounds; Herb-Drug Interactions; Hydroxytestosterones; Immunosuppressive Agents; Injections, Intravenous; Ketoconazole; Male; Microsomes, Liver; Phenanthrenes; Rats, Sprague-Dawley | 2014 |
Glycyrrhizin accelerates the metabolism of triptolide through induction of CYP3A in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Diterpenes; Drug Interactions; Enzyme Induction; Epoxy Compounds; Female; Glycyrrhizic Acid; Ketoconazole; Liver; Male; Phenanthrenes; Rats; Rats, Wistar; Tandem Mass Spectrometry; Tripterygium | 2014 |
Effect of CYP3A4 on liver injury induced by triptolide.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dexamethasone; Diterpenes; Epoxy Compounds; Female; Ketoconazole; Liver; Mass Spectrometry; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Phenanthrenes | 2020 |