ketoconazole and trimethoprim

ketoconazole has been researched along with trimethoprim in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (20.93)	18.7374
1990's	1 (2.33)	18.2507
2000's	15 (34.88)	29.6817
2010's	18 (41.86)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Gao, F; Huang, G; Xiao, J	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Keserü, GM	1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK	1
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Jia, L; Sun, H	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Anderson, KS; Atreya, C; Babatunde, O; Jorgensen, WL; Martucci, WE; Udier-Blagovic, M; Vargo, MA	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Sen, S; Sinha, N	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW	1
Hunziker, UA; Jendis, JB; Nadal, D; Schüpbach, J; Seger, RA; Tomasik, Z; Wetzel, JC	1
Fischer, A; Griscelli, C; Mouy, R; Seger, R; Vilmer, E	1
Ramírez-Ronda, CH; Santana, JL	1
de Pauw, BE; Haanen, C; Stalpers, LJ; Verhagen, C	1
Bremer, HJ; Koletzko, B; Wendel, U	1
Bircher, A; Furger, F; Lang, W; Lüthy, R; Maurer, R; Siegenthaler, W; Vogt, M	1
Bodey, GP; Estey, E; Fainstein, V; Freireich, EJ; Keating, M; Maksymiuk, A; McCredie, KB; Smith, T	1
Cruciani, M; Klastersky, J; Meunier-Carpentier, F	1
Berman, JD; Lee, LS	1
Fraser-Smith, EB; Freitas, VR; Matthews, TR	1
DeVane, CL; Wang, JS	1
Hu, JH; Qian, M; Shi, LF	1
Kukanich, B; Kukanich, KS; Rodriguez, JR	1
Block, SL	1
KuKanich, B; KuKanich, K	1

Reviews

2 review(s) available for ketoconazole and trimethoprim

Article	Year
Current scenario of tetrazole hybrids for antibacterial activity. European journal of medicinal chemistry, 2019, Dec-15, Volume: 184 Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles	2019
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

3 trial(s) available for ketoconazole and trimethoprim

Article	Year
Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two. Archives of internal medicine, 1984, Volume: 144, Issue:8 Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Drug Combinations; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Humans; Ketoconazole; Leukemia; Middle Aged; Mycoses; Pneumonia; Sepsis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1984
Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients. European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:1 Topics: Agranulocytosis; Antifungal Agents; Candidiasis; Drug Combinations; Female; Humans; Imidazoles; Ketoconazole; Male; Miconazole; Middle Aged; Mycoses; Neoplasms; Neutropenia; Piperazines; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1983
The effects of concurrent administration of cytochrome P-450 inhibitors on the pharmacokinetics of oral methadone in healthy dogs. Veterinary anaesthesia and analgesia, 2011, Volume: 38, Issue:3 Topics: Administration, Oral; Analgesics, Opioid; Animals; Area Under Curve; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Therapy, Combination; Female; Fluoxetine; Ketoconazole; Male; Methadone; Prospective Studies; Trimethoprim	2011

Other Studies

38 other study(ies) available for ketoconazole and trimethoprim

Article	Year
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Identification and prediction of promiscuous aggregating inhibitors among known drugs. Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21 Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship	2003
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen	2007
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Novel non-active site inhibitor of Cryptosporidium hominis TS-DHFR identified by a virtual screen. Bioorganic & medicinal chemistry letters, 2009, Jan-15, Volume: 19, Issue:2 Topics: Allosteric Site; Animals; Catalytic Domain; Cryptosporidium; Enzyme Inhibitors; Folic Acid Antagonists; Models, Molecular; Tetrahydrofolate Dehydrogenase	2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1). Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7 Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries	2017
Stable human immunodeficiency virus encephalopathy in two infants receiving early intravenous gammaglobulin plus antimicrobial prophylaxis. European journal of pediatrics, 1989, Volume: 148, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Brain Diseases; Drug Combinations; Drug Therapy, Combination; HIV Antibodies; HIV Antigens; Humans; Immunoglobulin G; Immunoglobulins, Intravenous; Infant; Infant, Newborn; Ketoconazole; Male; Neurologic Examination; Opportunistic Infections; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1989
Incidence, severity, and prevention of infections in chronic granulomatous disease. The Journal of pediatrics, 1989, Volume: 114, Issue:4 Pt 1 Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Drug Combinations; Genetic Linkage; Granulomatous Disease, Chronic; Humans; Infant; Infant, Newborn; Ketoconazole; Mycoses; Paris; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; X Chromosome	1989
[The pregnant woman infected with the human immunodeficiency virus: recommendations for her management]. Boletin de la Asociacion Medica de Puerto Rico, 1988, Volume: 80, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Candidiasis; Cytomegalovirus Infections; Female; Humans; Ketoconazole; Opportunistic Infections; Pneumonia, Pneumocystis; Pregnancy; Pregnancy Complications, Infectious; Sulfamethoxazole; Toxoplasmosis; Trimethoprim	1988
Drug-induced skin reactions in patients with acute non-lymphocytic leukaemia. European journal of haematology, 1987, Volume: 38, Issue:3 Topics: Acute Disease; Adult; Allopurinol; Cephalosporins; Drug Combinations; Drug Eruptions; Female; Humans; Ketoconazole; Leukemia; Male; Miconazole; Penicillins; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1987
Lithium for treatment of neutropenia in glycogen storage disease type Ib. The Journal of pediatrics, 1986, Volume: 109, Issue:5 Topics: Agranulocytosis; Chlorides; Drug Combinations; Drug Therapy, Combination; Female; Glycogen Storage Disease Type I; Hematopoiesis; Humans; Ketoconazole; Leukocyte Count; Lithium; Lithium Chloride; Neutropenia; Skin Diseases, Infectious; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1986
[Heterosexual transmission of the acquired immunodeficiency syndrome (AIDS)]. Deutsche medizinische Wochenschrift (1946), 1985, Sep-27, Volume: 110, Issue:39 Topics: Acquired Immunodeficiency Syndrome; Adult; Bone Marrow Examination; Bronchi; Candidiasis; Cerebral Infarction; Child, Preschool; Coitus; Demyelinating Diseases; Drug Combinations; Female; Humans; Ketoconazole; Male; Pneumocystis; Pneumonia; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1985
Activity of oral drugs against Leishmania tropica in human macrophages in vitro. The American journal of tropical medicine and hygiene, 1983, Volume: 32, Issue:5 Topics: Antiprotozoal Agents; Cells, Cultured; Drug Interactions; Humans; Isoniazid; Ketoconazole; Leishmania; Macrophages; Metronidazole; Nitrofurans; Phenothiazines; Quinacrine; Rifampin; Sulfamethoxazole; Trimethoprim	1983
Efficacy of ganciclovir in combination with other antimicrobial agents against cytomegalovirus in vitro and in vivo. Antiviral research, 1993, Volume: 20, Issue:1 Topics: Amphotericin B; Animals; Antifungal Agents; Antiviral Agents; Cells, Cultured; Cytomegalovirus Infections; Dapsone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Ganciclovir; Humans; Ketoconazole; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Species Specificity; Sulfamethoxazole; Survival Analysis; Trimethoprim; Viral Plaque Assay	1993
Dofetilide for atrial fibrillation. The Medical letter on drugs and therapeutics, 2000, May-15, Volume: 42, Issue:1078 Topics: Anti-Arrhythmia Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Anti-Ulcer Agents; Antifungal Agents; Atrial Fibrillation; Cimetidine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Humans; Ketoconazole; Phenethylamines; Potassium Channel Blockers; Sulfamethoxazole; Sulfonamides; Torsades de Pointes; Trimethoprim	2000
Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro. Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:6 Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; In Vitro Techniques; Isoenzymes; Ketoconazole; Methadone; Microsomes, Liver; Paroxetine; Pyrrolidines; Recombinant Proteins; Stereoisomerism; Trimethoprim	2003
[Enzyme kinetics of ligustilide metabolism in rat liver microsomes]. Yao xue xue bao = Acta pharmaceutica Sinica, 2009, Volume: 44, Issue:4 Topics: 4-Butyrolactone; Animals; Benzoflavones; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes; Ketoconazole; Kinetics; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Trimethoprim	2009
Tricky triggers of intertrigo. Pediatric annals, 2014, Volume: 43, Issue:5 Topics: Acyclovir; Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antiviral Agents; Candidiasis; Child, Preschool; Clindamycin; Female; Herpes Simplex; Humans; Infant; Infant, Newborn; Intertrigo; Ketoconazole; Male; Staphylococcal Infections; Sulfamethoxazole; Trimethoprim	2014
Chloramphenicol significantly affects the pharmacokinetics of oral methadone in Greyhound dogs. Veterinary anaesthesia and analgesia, 2015, Volume: 42, Issue:6 Topics: Administration, Oral; Analgesics, Opioid; Animals; Chloramphenicol; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Interactions; Female; Fluoxetine; Ketoconazole; Male; Medetomidine; Methadone; Trimethoprim	2015