ketoconazole has been researched along with triazoles in 217 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 82 (37.79) | 18.7374 |
| 1990's | 28 (12.90) | 18.2507 |
| 2000's | 50 (23.04) | 29.6817 |
| 2010's | 48 (22.12) | 24.3611 |
| 2020's | 9 (4.15) | 2.80 |
| Authors | Studies |
|---|---|
| Andrade, J; Armstrong, D; Edwards, F; Niki, Y; Schmitt, HJ | 1 |
| Bava, AJ; Negroni, R | 1 |
| Antonacci, B; Cacciapuoti, A; Hare, RS; Loebenberg, D; Menzel, F; Miller, GH; Moss, EL; Norris, C; Parmegiani, R; Yarosh-Tomaine, T | 1 |
| Clark, JE; Harder, DR; Kauser, K; Ma, YH; Masters, BS; Ortiz de Montellano, PR; Roman, RJ | 1 |
| Graybill, JR; Sharkey, PK | 1 |
| de Souza, W; Lazardi, K; Urbina, JA | 1 |
| Brummer, E; Hanson, LH; Stevens, DA | 1 |
| Hector, RF; Yee, E | 1 |
| Defaveri, J; Graybill, JR; Sun, SH | 1 |
| Defaveri, J; Graybill, JR | 1 |
| Perfect, JR; Ritter, W; Wright, KA | 1 |
| Adams, DJ; Brown, SB; Dickinson, K; Evans, EG; Hitchcock, CA | 1 |
| Bellens, D; Janssen, PA; Roels, I; Vanden Bossche, H; Willemsens, G | 1 |
| Cook, RA; Galgiani, JN; McIntyre, KA | 1 |
| Kawasaki, K; Matsunaga, T; Uchida, K; Yamaguchi, H | 1 |
| Dupont, B | 1 |
| Mattie, H; van Furth, R; Van t Wout, JW | 1 |
| Martin, MV | 1 |
| Charuel, C; Latrille, F; Lodola, A | 1 |
| Kobayashi, GS; Spitzer, ED | 1 |
| Graybill, JR | 2 |
| Goldberg, DJ; Green, ST; Kennedy, DH; McGuire, W; Nathwani, D | 1 |
| Fransen, J; Janssen, PA; Van Cutsem, J; Van Gerven, F | 1 |
| Clumeck, N; De Wit, S; Goossens, H; Weerts, D | 1 |
| Brummer, E; Hanson, LH; Stevens, DA; Tucker, RM | 1 |
| Polak, A | 2 |
| Houston, JB; Humphrey, MJ; Matthew, DE; Tarbit, MH | 1 |
| Dismukes, WE; Saag, MS | 1 |
| Walsh, TJ | 1 |
| Beggs, WH; Bennett, RL; Hughes, CE; Tuna, IC | 1 |
| Senior, DS; Shaw, JT | 1 |
| Abadie, SM; Greer, DL; Noel, SB; Pankey, GA; Zachary, JA | 1 |
| Dismukes, WE | 1 |
| Hanger, DP; Jevons, S; Shaw, JT | 1 |
| Coulaud, JP; Ngo Van, P | 1 |
| Drew, RH; Gallis, HA; Perfect, JR | 1 |
| Pizzo, A; Walsh, TJ | 1 |
| Gordon, MA; Lapa, EW; Passero, PG | 1 |
| Beach, DH; Goad, LJ; Holz, GG | 1 |
| Bähr, V; Eckhoff, C; Oelkers, W | 1 |
| Odds, FC; Webster, CE | 1 |
| Faergemann, J | 1 |
| Brammer, KW; Feczko, JM | 1 |
| Hay, RJ | 1 |
| Stevens, DA | 1 |
| Brammer, KW; Kutzer, E; Leodolter, S; Oittner, R | 1 |
| Bennett, JE; Kan, VL | 1 |
| Ackerbauer, H; Meingassner, JG; Mieth, H | 1 |
| Brammer, KW; Marriott, MS; Richardson, K; Troke, PF | 1 |
| Durack, DT; Perfect, JR | 1 |
| Abbott, AB; Cockayne, A; Hayward, J; Odds, FC | 1 |
| Andrews, RJ; Brammer, KW; Marriott, MS; Richardson, K; Troke, PF | 1 |
| Durack, DT; Perfect, JR; Savani, DV | 1 |
| Cauwenbergh, G | 1 |
| Ahrens, J; Graybill, JR; Sun, SH | 1 |
| Hopwood, V; Johnson, EM; Kennedy, CT; Smith, KJ; Van Cutsem, J; Vanden Bossche, H; Warnock, DW | 1 |
| Abruzzo, GK; Bulmer, GS; Fromtling, RA | 1 |
| Meingassner, JG; Schaude, M | 1 |
| Graybill, JR; Palou de Fernandez, E; Patino, MM; Tarbit, MH | 1 |
| Ahrens, J; Graybill, JR; Palou, E | 1 |
| Galgiani, JN; Rogers, TE | 1 |
| Cobo, LM; Durack, DT; Perfect, JR; Savani, DV | 1 |
| Beggs, WH; Hughes, CE | 2 |
| Dixon, DM; Polak, A | 1 |
| Andrews, RJ; Marriott, MS; Richardson, K; Troke, PF | 1 |
| Abruzzo, GK; Fromtling, RA; Giltinan, DM; Turnbull, TA | 1 |
| Bastide, JM; Bastide, M; Jouvert, S; Lebecq, JC; Mallie, M; Montes, B | 1 |
| Holmberg, K | 1 |
| Meunier, F | 1 |
| Hoeprich, PD; Merry, JM | 2 |
| Gugnani, HC; Okeke, CN | 1 |
| Brummer, E; Hoyos, GL; Lefler, E; McEwen, JG; Restrepo, A; Stevens, DA | 1 |
| Lefler, E; Stevens, DA | 1 |
| Brummer, E; Lefler, E; Perlman, AM; Stevens, DA | 1 |
| Durack, DT; Smego, RA | 1 |
| Espinel-Ingroff, A; Gebhart, RJ; Shadomy, S | 1 |
| Abbott, AB; Odds, FC; Webster, CE | 1 |
| Hiratani, T; Plempel, M; Yamaguchi, H | 1 |
| Drutz, DJ; Graybill, JR; Kaster, SR | 2 |
| Fromtling, RA; Shadomy, S; Yu, HP | 2 |
| Muller, G; Sobel, JD | 1 |
| Nusch, W; Plempel, M | 1 |
| Plempel, M | 2 |
| Levine, HB | 1 |
| Barrett-Bee, KJ; Ryley, JF; Wilson, RG | 1 |
| Espinel-Ingroff, A; Kerkering, TM; Shadomy, S | 1 |
| Gerding, DN; Harris, C; Hughes, CE; Moody, JA; Peterson, LR | 1 |
| Backx, LJ; Heeres, J; Van Cutsem, J | 1 |
| Staben, C | 1 |
| Benveniste, P; Chaubet, N; Gigot, C; Grausem, B; Loper, JC | 1 |
| Denning, DW; Law, D; Mason, C; Moore, CB; Wardle, HM | 1 |
| Bomont, HL; Houston, JB; Humphrey, MJ; Tarbit, MH | 1 |
| Bartlett, MS; Queener, SF; Richardson, JD; Shaw, MM; Smith, JW | 1 |
| Hiratani, T; Yamaguchi, H | 1 |
| Maldonado, RA; Molina, J; Payares, G; Urbina, JA | 1 |
| Lazardi, K; Liendo, A; Molina, J; Payares, G; Perez, N; Piras, MM; Piras, R; Ryley, JF; Sanoja, C; Urbina, JA; Wincker, P | 1 |
| Dagger, F; Hernandez, A; Liendo, A; Rangel, H; Urbina, JA | 1 |
| Carver, PL; Kauffman, CA | 1 |
| Hernanz Hermosa, JM; Lázaro Ochaita, P | 1 |
| Brodie, AM; Grigoryev, DN; Kato, K; Long, BJ; Njar, VC; Nnane, IP | 1 |
| Nguyen, MH; Yu, CY | 1 |
| Ringdahl, EN | 1 |
| Boepple, PA; Crowley, WF; DeCruz, S; Hayes, FJ; Seminara, SB | 1 |
| Bray, MJ; Schnorr, JA; Veldhuis, JD | 1 |
| Crego, AL; Gómez, J; Lavandera, JL; Marina, ML | 1 |
| Feng, XT; Liu, CM; Ma, MC; Wu, YJ; Zhang, DZ; Zhou, TS | 1 |
| Baker, GB; Rotzinger, S | 1 |
| Ellepola, AN; Samaranayake, LP | 1 |
| Ichihara, S; Murasaki, C; Ohwada, J; Shimma, N; Umeda, I; Yamazaki, T | 1 |
| Hyland, R; Jones, BC; Smith, DA | 1 |
| del Palacio, A; Garau, M; Pereiro, M | 1 |
| Ahmadi, M; Le Baut, G; Le Borgne, M; Marchand, P; Nicholls, PJ; Smith, HJ | 1 |
| Alfaro, CL; Ereshefsky, L; Lam, YW; Miller, M | 1 |
| Bliss, JM; Gigliotti, F; Wellington, M | 1 |
| De Waard, MA; Kema, GH; Stergiopoulos, I; van Nistelrooy, JG | 1 |
| Blanchard, AP; Broudy, MI; Cargill, CE; Crespi, CL; Dandeneau, AA; Dehal, SS; Erve, JC; Goodwin, JJ; Ho, T; Patten, CJ; Sharma, R; Stresser, DM; Turner, SD | 1 |
| Ausma, J; Borgers, M; Heeres, J; Meerpoel, L; Odds, F; Van Gerven, F; Vanden Bossche, H; Woestenborghs, F | 1 |
| Maertens, JA | 1 |
| DeMario, M; Desai, AA; Fleming, GF; Innocenti, F; Janisch, L; Ramirez, J; Ratain, MJ; Shepard, D | 1 |
| Wark, P | 1 |
| Yasuda, MA | 1 |
| Alía-Aponte, C; Baró-Tomás, T; Jiménez-Cabello, T; Lázera, MS; Morera-López, Y; Torres-Rodríguez, JM | 1 |
| Niwa, T; Shiraga, T; Takagi, A | 1 |
| Castro-Puyana, M; Crego, AL; Marina, ML | 1 |
| Bagg, J; Coulter, WA; Kuriyama, T; Lewis, MA; Ready, D; Williams, DW | 1 |
| Almeida, D; de Nazareth S L de Meirelles, M; Pereira, MC; Silva, DT; Urbina, JA | 1 |
| Ausma, J; Borgers, M; Faergemann, J | 1 |
| Cepero de García, MC; Espinel-Ingroff, A; Rincón, S | 1 |
| Cano, J; Gené, J; Gilgado, F; Guarro, J; Serena, C | 1 |
| De Waard, MA; Kema, GH; Roohparvar, R; Zwiers, LH | 1 |
| Costa, CR; de Araujo, CR; de Fátima Lisboa Fernandes, O; do Rosário Rodrigues Silva, M; Miranda, KC; Passos, XS | 1 |
| da Silva Barros, ME; de Assis Santos, D; Soares Hamdan, J | 1 |
| Ayadi, A; Ben Salah, S; Ben Zina, Z; Cheikrouhou, F; Colin, J; Feki, J; Makni, F; Mlik, M | 1 |
| Alvarado-Ramírez, E; Torres-Rodríguez, JM | 1 |
| Almyroudis, NG; Fothergill, AW; Kusne, S; Rinaldi, MG; Sutton, DA | 1 |
| Gupta, A; Mao, Q; Unadkat, JD | 1 |
| Alton, KB; Chowdhury, SK; Ghosal, A; Hapangama, N; Kishnani, NS; Ramanathan, R; Yuan, Y | 1 |
| Carrillo-Muñoz, AJ; Casals, JB; del Valle, O; Estivill, MD; Ezkurra, PA; Giusiano, G; Quindós, G; Santos, P | 1 |
| Abel, S; Muirhead, GJ; Ridgway, CE; Russell, D; Taylor-Worth, RJ | 1 |
| Collins, C; Dickins, M; Hyland, R; Jones, B; Jones, H | 1 |
| Anderson, R; Steel, HC; Tintinger, GR | 1 |
| Dupont, I; Jassogne, C; Larondelle, Y; McAlister, D; Muller, M; Pussemier, L; Ribonnet, L; Schneider, YJ; Scippo, ML; Sergent, T; van der Heiden, E | 1 |
| Nawrot, U; Nowicka, J; Wlodarczyk, K | 1 |
| Lenie, S; Smitz, J | 1 |
| Krishna, G; Ma, L; Martinho, M; McLeod, J; Moton, A; Savant, I; Seiberling, M | 1 |
| Ambudkar, SV; Manoharlal, R; Prasad, R; Prasad, T; Puri, N; Sharma, M; Shukla, S | 1 |
| Brilhante, RS; Cordeiro, Rde A; de Camargo, ZP; de Lima, RA; Medrano, DJ; Monteiro, AJ; Rocha, MF; Sidrim, JJ; Tavares, JL | 1 |
| Avolio, M; Bruschetta, G; Camporese, A; De Rosa, R; Grosso, S | 1 |
| Accoceberry, I; Bernadou, JM; Breilh, D; Gordien, JB; Pigneux, A; Rouault, A; Saux, MC; Tabrizi, R; Vigouroux, S | 1 |
| Castro-Puyana, M; Chankvetadze, B; Chankvetadze, L; Crego, AL; Lomsadze, K; Marina, ML; Martínez-Girón, AB; Salgado, A | 1 |
| Almeida, LM; Bianchin, DB; Souza, EA; Svidzinski, TI | 1 |
| Kamataki, T; Kawai, R; Murai, K; Nakagawa, K; Yamazaki, H | 1 |
| Kelly, DE; Kelly, SL; Lamb, DC; Martel, CM; Melo, N; Nes, WD; Parker, JE; Warrilow, AG | 1 |
| Heeres, J; Lewi, P; Meerpoel, L | 1 |
| Bader, O; Gross, U; Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Rolley, N; Warrilow, AG; Weig, M | 1 |
| Fahal, AH; van Belkum, A; van de Sande, WW | 1 |
| Jain, GK; Manickavasagam, L; Mishra, S | 1 |
| Greenhaw, J; Salminen, WF; Shi, Q; Yang, X | 1 |
| Alves, SH; Azevedo, MI; Botton, SA; Dutra, V; Jesus, FP; Lautert, C; Machado, ML; Mahl, DL; Santurio, JM; Zanette, RA | 1 |
| Doshi, U; Li, AP | 1 |
| Brock, B; Ly, VT | 1 |
| Meurman, JH; Pärnänen, P; Samaranayake, LP; Seneviratne, CJ; Vaara, M; Wong, SS; Yuen, KY | 1 |
| Al-Nawas, B; Karbach, J; Walter, C | 1 |
| Cafarchia, C; Figueredo, LA; Iatta, R; Montagna, MT; Otranto, D | 1 |
| Asami, T; Oh, K; Yamada, K; Yoshizawa, Y | 1 |
| Chen, TC; Chen, YC; Chen, YH; Lu, PL | 1 |
| Acharya, V; Farside, A; MacNeill, R; Moussallie, M; Stromeyer, R; Urbanowicz, B | 1 |
| Chen, Y; Groothuis, GM; Hadi, M; Merema, MT; Starokozhko, V | 1 |
| Curfs-Breuker, I; Fahal, AH; Kloezen, W; Meis, JF; van de Sande, WW | 1 |
| Inoue, A; Kaneko, H; Kawamura, A; Matsumoto, S; Ohbuchi, M; Usui, T; Yamazoe, Y; Yoshinari, K | 1 |
| Kelly, DE; Kelly, SL; Parker, JE; Warrilow, AG | 1 |
| Gärtner, P; Knoth, H; Petry, T | 1 |
| Kubickova, B; Martinkova, M; Stiborova, M | 1 |
| Gude, T; Kulkarni, MM; McGwire, BS; Reddy, N | 1 |
| Cuenca-Estrella, M; Escribano, P; Guinea, J; Martín-Mazuelos, E; Pemán, J; Sánchez-Reus, F; Zaragoza, Ó | 1 |
| Jiang, J; Mathur, R; Pandharkar, T; Schmittgen, TD; Shaha, C; Werbovetz, KA; Zhu, X | 1 |
| Ahmed, SA; de Hoog, GS; Duncanson, F; Fahal, AH; Kloezen, W; van de Sande, WW; Zijlstra, EE | 1 |
| Nantasenamat, C; Pingaew, R; Prachayasittikul, S; Prachayasittikul, V; Ruchirawat, S | 1 |
| Fukami, T; Nakajima, M; Oda, S; Takai, S; Tsuneyama, K; Yokoi, T | 1 |
| Bulanda, M; Jagielski, T; Skóra, M | 1 |
| Buettner, B; Knoth, H; Scriba, GK | 1 |
| Augustijns, P; Brouwers, J; Kourentas, A; Reppas, C; Stavrinoudakis, N; Symillides, M; Symillidis, A; Vertzoni, M | 1 |
| Ankley, GT; Jensen, KM; Mayo, M; Perkins, EJ; Villeneuve, DL; Watanabe, KH | 1 |
| Büyükünal, C; Ceylaner, S; Ercan, O; Evliyaoğlu, O; Özcabı, B; Özcan, R; Tahmiscioğlu Bucak, F; Tüysüz, B | 1 |
| Cristofoletti, R; Dressman, JB; Patel, N | 2 |
| Abbott, DH; Bird, IM | 1 |
| Chi, Z; Ding, L; Li, L; Ma, P; Shu, C; Tao, L; Wang, K; Wei, J; Wu, Y | 1 |
| Brown, MS; Das, A; De Brabander, JK; Goldstein, JL; Li, X; Liang, Q; Lu, F; Trinh, MN | 1 |
| Chen, C; Han, HS; Kano, R; Noli, C | 1 |
| Khan, AA; LeDuc, BW; Shaik, AN | 1 |
| Almeida-Paes, R; Brito-Santos, F; Figueiredo-Carvalho, MHG; Gutierrez-Galhardo, MC; Machado, ACS; Oliveira, MME; Pereira, SA; Zancopé-Oliveira, RM | 1 |
| Baj, F; Baravalle, R; Ciaramella, A; Di Nardo, G; Gilardi, G | 1 |
| Bhaskar, JP; Gayathri, S; Krishnan, V; Pandian, SK; Sivasankar, C | 1 |
| McComiskey, KPM; Tajber, L | 1 |
| Agnihotri, S; Aldape, KD; Bunda, S; Burrell, K; Chen, EX; Jalali, S; Karimi, S; Kumar, S; Li, M; Liu, J; Mamatjan, Y; Mansouri, A; Mansouri, S; Nejad, R; Singh, O; Singh, SK; Vartanian, A; Zadeh, G | 1 |
| Shen, L; Tu, F; Wang, J; Wang, R; Xia, G; Xu, J; Ye, C; Yi, Y; Yu, C; Zheng, Z | 1 |
| Anderson, MS; Fan, L; Iwamoto, M; Khalilieh, SG; Laethem, T; Rasmussen, S; Sanchez, RI; Sura, M; van Bortel, L; van Lancker, G; Yee, KL | 1 |
| Chakravarthy, M; Kraft, WK; Liu, W; Mangin, E; Martinez-Cantarin, MP; McCrea, JB; Panebianco, D; Wrishko, RE; Yee, KL | 1 |
| Chen, M; Chen, R; Chen, Y; Hu, G; Huang, C; Sun, W; Wang, Z; Zhang, X | 1 |
| Dastgheib, L; Ghasemi, N; Jowkar, F; Nouraei, H; Pakshir, K; Zomorodian, K | 1 |
| Harada, K; Inagaki, K; Kampirapap, K; Koga, H; Maeda, J; Makimura, K; Nanjoh, Y; Neki, D; Reangchainam, S; Tsuboi, R; Yuasa, K | 1 |
| Abou El-Alamin, MM; Aboul-Enein, HY; Atia, MA; Sultan, MA | 1 |
| Aala, F; Badali, H; Barac, A; Daie Ghazvini, R; Fatahi, N; Ghaffari, M; Hashemi, SJ; Izadi, A; Khodavaisy, S; Rezaie, S; Salehi, Z; Taran, M | 1 |
| Cheng, G; Huang, L; Li, T; Luo, X; Xue, X; Zhang, Y | 1 |
| Carreño, FO; Cohen-Wolkowiez, M; Edginton, AN; Gonzalez, D; Salerno, SN | 1 |
| Amidon, GE; Kataoka, M; Minami, K; Takagi, T; Yamashita, S | 1 |
| Li, AP; Wei, H | 1 |
| Nunes Rodrigues, TC; Vandenabeele, SI | 1 |
21 review(s) available for ketoconazole and triazoles
| Article | Year |
|---|---|
Fungal infections and their management.
Topics: Amphotericin B; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses; Naphthalenes; Terbinafine; Triazoles | 1990 |
From 14 alpha-demethylase inhibitors in fungal cells to androgen and oestrogen biosynthesis inhibitors in mammalian cells.
Topics: Androgen Antagonists; Animals; Antifungal Agents; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estrogen Antagonists; Humans; Imidazoles; Ketoconazole; Oxidoreductases; Sterol 14-Demethylase; Triazoles | 1990 |
Testing of organisms for susceptibility to triazoles: is it justified?
Topics: Antifungal Agents; Drug Resistance, Microbial; Fluconazole; Fungi; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mycoses; Triazoles | 1989 |
New antifungal agents.
Topics: Aminoglycosides; Anti-Bacterial Agents; Antifungal Agents; Azoles; Echinocandins; Fluconazole; Fungi; Humans; Itraconazole; Ketoconazole; Mycoses; Peptides; Peptides, Cyclic; Triazoles | 1989 |
Azole antifungal agents: emphasis on new triazoles.
Topics: Animals; Antifungal Agents; Chemical Phenomena; Chemistry; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses; Triazoles | 1988 |
Recent advances in the treatment of systemic fungal infections.
Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antifungal Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Mycoses; Triazoles | 1987 |
Azole antifungal drugs: old and new.
Topics: Animals; Antifungal Agents; Azoles; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mycoses; Triazoles | 1988 |
Treatment of systemic fungal infections: recent progress and current problems.
Topics: Amphotericin B; Antifungal Agents; Chemical Phenomena; Chemistry; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Mycoses; Triazoles | 1988 |
New oral treatments for dermatophytosis.
Topics: Administration, Oral; Antifungal Agents; Dermatomycoses; Fluconazole; Itraconazole; Ketoconazole; Naphthalenes; Terbinafine; Triazoles | 1988 |
Systemic fungal infections: diagnosis and treatment. I. Therapeutic agents.
Topics: Amphotericin B; Antifungal Agents; Humans; Ketoconazole; Mycoses; Triazoles | 1988 |
Use of azoles for systemic antifungal therapy.
Topics: Antifungal Agents; Drug Interactions; Drug Resistance, Microbial; Fluconazole; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Mycoses; Triazoles | 1997 |
[Superficial mycoses in immunosuppressed patients].
Topics: Adult; Antifungal Agents; Candidiasis, Cutaneous; Candidiasis, Oral; Candidiasis, Vulvovaginal; Child; Dermatitis, Seborrheic; Dermatomycoses; Female; Fluconazole; Humans; Imidazoles; Immunosuppression Therapy; Itraconazole; Ketoconazole; Male; Morpholines; Onychomycosis; Tinea; Tinea Versicolor; Transplantation; Triazoles | 1995 |
Treatment of recurrent vulvovaginal candidiasis.
Topics: Antifungal Agents; Boric Acids; Candidiasis, Vulvovaginal; Clotrimazole; Drug Interactions; Female; Fluconazole; Humans; Ketoconazole; Patient Education as Topic; Recurrence; Risk Factors; Teaching Materials; Time Factors; Triazoles | 2000 |
Oral candidal infections and antimycotics.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Anti-Infective Agents, Local; Antifungal Agents; Candida; Candidiasis, Oral; Chlorhexidine; Clotrimazole; Drug Resistance, Fungal; Fluconazole; Flucytosine; Humans; Immunocompromised Host; Itraconazole; Ketoconazole; Miconazole; Mouth; Nystatin; Opportunistic Infections; Saliva; Treatment Failure; Triazoles | 2000 |
Antifungal pharmacotherapy for neonatal candidiasis.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Caspofungin; Cross Infection; Echinocandins; Fluconazole; Flucytosine; Fungal Proteins; Fungemia; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Ketoconazole; Lipopeptides; Peptides; Peptides, Cyclic; Pyrimidines; Triazoles; Voriconazole | 2003 |
History of the development of azole derivatives.
Topics: Antifungal Agents; Azoles; Drug Resistance, Fungal; Fluconazole; Itraconazole; Ketoconazole; Pyrimidines; Triazoles; Voriconazole | 2004 |
Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment.
Topics: Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Azoles; Evidence-Based Medicine; Forecasting; Humans; Itraconazole; Ketoconazole; Pyrimidines; Triazoles; Voriconazole | 2004 |
Pharmacological management of paracoccidioidomycosis.
Topics: Amphotericin B; Central Nervous System Fungal Infections; Drug Resistance; Fluconazole; Follow-Up Studies; Humans; Immunocompromised Host; Itraconazole; Ketoconazole; Paracoccidioidomycosis; Pyrimidines; Sulfonamides; Triazoles; Voriconazole | 2005 |
[Drug-drug interaction of antifungal drugs].
Topics: Antifungal Agents; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Echinocandins; Fluconazole; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Lipopeptides; Lipoproteins; Micafungin; Miconazole; Microsomes, Liver; Peptides, Cyclic; Pyrimidines; Triazoles; Voriconazole | 2005 |
Conazoles.
Topics: Antifungal Agents; Fluconazole; Itraconazole; Ketoconazole; Miconazole; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Triazoles; Voriconazole | 2010 |
The hunt for a selective 17,20 lyase inhibitor; learning lessons from nature.
Topics: Adrenal Hyperplasia, Congenital; Androstadienes; Androstenes; Antineoplastic Agents; Benzimidazoles; Cytochrome P-450 CYP3A Inhibitors; Drug Therapy, Combination; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Male; Naphthalenes; Prednisone; Prostate; Prostatic Neoplasms; Protective Factors; Steroid 17-alpha-Hydroxylase; Triazoles | 2016 |
11 trial(s) available for ketoconazole and triazoles
| Article | Year |
|---|---|
Comparison of fluconazole and ketoconazole for oropharyngeal candidiasis in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Aged; AIDS-Related Complex; Candidiasis, Oral; Clinical Trials as Topic; Double-Blind Method; Female; Fluconazole; Follow-Up Studies; Humans; Ketoconazole; Male; Middle Aged; Oropharynx; Pharyngeal Diseases; Prospective Studies; Recurrence; Triazoles | 1989 |
Fluconazole and testosterone: in vivo and in vitro studies.
Topics: Adult; Analysis of Variance; Animals; Antifungal Agents; Cells, Cultured; Double-Blind Method; Fluconazole; Humans; Ketoconazole; Leydig Cells; Male; Rats; Testosterone; Triazoles | 1988 |
Single-dose oral fluconazole in the treatment of vaginal candidosis.
Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Fluconazole; Humans; Ketoconazole; Triazoles | 1988 |
A comparison of fluconazole and ketoconazole in the oral treatment of vaginal candidiasis; report of a double-blind multicentre trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Fluconazole; Humans; Ketoconazole; Middle Aged; Multicenter Studies as Topic; Random Allocation; Recurrence; Triazoles | 1988 |
Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous gonadotropin-releasing hormone-stimulated luteinizing hormone and follicle-stimulating hormone secretion in young men.
Topics: Administration, Cutaneous; Adult; Anastrozole; Aromatase Inhibitors; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Estradiol; Feedback; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Ketoconazole; Luteinizing Hormone; Male; Nitriles; Prospective Studies; Testosterone; Triazoles | 2001 |
Pharmacokinetic and pharmacodynamic interactions of oral midazolam with ketoconazole, fluoxetine, fluvoxamine, and nefazodone.
Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Fluoxetine; Fluvoxamine; Humans; Ketoconazole; Male; Midazolam; Piperazines; Triazoles | 2003 |
A phase I trial of pharmacokinetic modulation of carboxyamidotriazole (CAI) with ketoconazole in patients with advanced cancer.
Topics: Adult; Aged; Antifungal Agents; Antineoplastic Agents; Capsules; Chemistry, Pharmaceutical; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Female; Humans; Ketoconazole; Male; Middle Aged; Neoplasms; Triazoles | 2004 |
Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.
Topics: Adolescent; Anti-HIV Agents; Antifungal Agents; Atazanavir Sulfate; CCR5 Receptor Antagonists; Cyclohexanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Ketoconazole; Male; Maraviroc; Middle Aged; Oligopeptides; Pyridines; Saquinavir; Statistics as Topic; Triazoles | 2008 |
Effects of oral posaconazole on the pharmacokinetic properties of oral and intravenous midazolam: a phase I, randomized, open-label, crossover study in healthy volunteers.
Topics: Adult; Anti-Anxiety Agents; Antifungal Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Half-Life; Humans; Injections, Intravenous; Ketoconazole; Male; Midazolam; Middle Aged; Triazoles | 2009 |
A highly sensitive LC-MS/MS method for determination of ketoconazole in human plasma: Application to a clinical study of the exposure to ketoconazole in patients after topical administration.
Topics: Administration, Topical; Adult; Chromatography, High Pressure Liquid; Dermatitis, Seborrheic; Drug Stability; Humans; Ketoconazole; Letrozole; Liquid-Liquid Extraction; Nitriles; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triazoles; Young Adult | 2016 |
Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects.
Topics: Administration, Oral; Adult; Azepines; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Diltiazem; Drug Interactions; Healthy Volunteers; Humans; Ketoconazole; Male; Middle Aged; Orexin Receptor Antagonists; Rifampin; Triazoles; Young Adult | 2019 |
185 other study(ies) available for ketoconazole and triazoles
| Article | Year |
|---|---|
Comparison of azoles against aspergilli in vitro and in an experimental model of pulmonary aspergillosis.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Aspergillus; Aspergillus flavus; Aspergillus fumigatus; Disease Models, Animal; Itraconazole; Ketoconazole; Male; Rats; Rats, Inbred Strains; Triazoles | 1992 |
Comparative study of six antifungal treatments in an experimental model of murine cryptococcosis.
Topics: Amphotericin B; Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Mice; Mice, Inbred BALB C; Triazoles | 1992 |
Comparison of SCH 39304, fluconazole, and ketoconazole for treatment of systemic infections in mice.
Topics: Administration, Oral; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Drug Evaluation, Preclinical; Fluconazole; Injections, Intravenous; Ketoconazole; Kidney; Male; Mice; Triazoles | 1992 |
Inhibitors of cytochrome P-450 attenuate the myogenic response of dog renal arcuate arteries.
Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dogs; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Ketoconazole; Kinetics; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Phosphorylcholine; Proadifen; Renal Artery; Triazoles | 1991 |
Ultrastructural alterations induced by ICI 195,739, a bis-triazole derivative with strong antiproliferative action against Trypanosoma (Schizotrypanum) cruzi.
Topics: Animals; Ergosterol; Ketoconazole; Naphthalenes; Terbinafine; Triazoles; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 1991 |
SCH 39304 in the treatment of acute or established murine pulmonary blastomycosis.
Topics: Animals; Antifungal Agents; Blastomycosis; Fluconazole; Ketoconazole; Lung Diseases; Mice; Mice, Inbred BALB C; Triazoles | 1991 |
Evaluation of Bay R 3783 in rodent models of superficial and systemic candidiasis, meningeal cryptococcosis, and pulmonary aspergillosis.
Topics: Administration, Oral; Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Cryptococcosis; Disease Models, Animal; Drug Administration Schedule; Evaluation Studies as Topic; Female; Fluconazole; Itraconazole; Ketoconazole; Lung Diseases, Fungal; Male; Meningitis; Mice; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains; Triazoles | 1990 |
Treatment of murine coccidioidal meningitis with SCH39304.
Topics: Animals; Antifungal Agents; Coccidioidomycosis; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluconazole; Itraconazole; Ketoconazole; Meningitis; Mice; Mice, Inbred BALB C; Triazoles | 1990 |
Treatment of chronic murine chromoblastomycosis with the triazole SCH39304.
Topics: Animals; Antifungal Agents; Chromoblastomycosis; Chronic Disease; Disease Models, Animal; Female; Itraconazole; Ketoconazole; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron; Mitosporic Fungi; Skin; Triazoles | 1990 |
The pharmacokinetics of BAY R3783 and its efficacy in the treatment of experimental cryptococcal meningitis.
Topics: Animals; Cryptococcosis; Cryptococcus neoformans; Fluconazole; Itraconazole; Ketoconazole; Meningitis; Rabbits; Triazoles | 1990 |
Interaction of azole antifungal antibiotics with cytochrome P-450-dependent 14 alpha-sterol demethylase purified from Candida albicans.
Topics: Antifungal Agents; Azoles; Candida albicans; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ferric Compounds; Ketoconazole; Mevalonic Acid; Oxidoreductases; Spectrum Analysis; Sterol 14-Demethylase; Triazoles | 1990 |
Effects of incubation temperature, inoculum size, and medium on agreement of macro- and microdilution broth susceptibility test results for yeasts.
Topics: Amphotericin B; Candida; Culture Media; Flucytosine; Ketoconazole; Microbial Sensitivity Tests; Temperature; Triazoles; Yeasts | 1990 |
[In vitro activity of fluconazole, a novel bistriazole antifungal agent].
Topics: Animals; Antifungal Agents; Ascitic Fluid; Aspergillus; Candida albicans; Culture Media; Dose-Response Relationship, Drug; Fluconazole; Humans; Hydrogen-Ion Concentration; Ketoconazole; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Triazoles; Yeasts | 1989 |
[Recent antifungal agents].
Topics: Allylamine; Animals; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Morpholines; Mycoses; Triazoles | 1989 |
Comparison of the efficacies of amphotericin B, fluconazole, and itraconazole against a systemic Candida albicans infection in normal and neutropenic mice.
Topics: Agranulocytosis; Amphotericin B; Animals; Antifungal Agents; Candida albicans; Candidiasis; Fluconazole; Half-Life; Itraconazole; Ketoconazole; Male; Mice; Neutropenia; Triazoles | 1989 |
A comparison of fluconazole and ketoconazole in the treatment of rat palatal candidosis.
Topics: Animals; Antifungal Agents; Candidiasis, Oral; Epithelium; Fluconazole; Image Processing, Computer-Assisted; Ketoconazole; Male; Microcomputers; Palate; Rats; Rats, Inbred Strains; Triazoles | 1989 |
A comparative study of the effects of ketoconazole and fluconazole on 17-beta estradiol production by rat ovaries in vitro.
Topics: Animals; Antifungal Agents; Estradiol; Female; Fluconazole; In Vitro Techniques; Ketoconazole; Ovary; Radioimmunoassay; Rats; Rats, Inbred Strains; Triazoles | 1989 |
New triazole antifungal agents (fluconazole and itraconazole) in the treatment of HIV-related gastrointestinal candidiasis.
Topics: Acquired Immunodeficiency Syndrome; Antifungal Agents; Candidiasis; Fluconazole; Gastrointestinal Diseases; Humans; Itraconazole; Ketoconazole; Triazoles | 1989 |
Treatment of experimental zygomycosis in guinea pigs with azoles and with amphotericin B.
Topics: Amphotericin B; Animals; Antifungal Agents; Azoles; Fluconazole; Guinea Pigs; Itraconazole; Ketoconazole; Male; Mucormycosis; Rhizopus; Triazoles | 1989 |
Fluconazole versus ketoconazole in oropharyngeal candidiasis in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Candidiasis, Oral; Female; Fluconazole; Humans; Ketoconazole; Male; Pharyngeal Diseases; Triazoles | 1989 |
Activity of ICI 195,739, a new oral triazole, compared with that of ketoconazole in the therapy of experimental murine blastomycosis.
Topics: Animals; Antifungal Agents; Blastomyces; Blastomycosis; Ketoconazole; Male; Mice; Mice, Inbred BALB C; Time Factors; Triazoles | 1989 |
Combination therapy of experimental candidiasis, cryptococcosis, aspergillosis and wangiellosis in mice.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Cryptococcosis; Drug Therapy, Combination; Exophiala; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Mice; Mycoses; Triazoles | 1987 |
Comparison of two azole antifungal drugs, ketoconazole, and fluconazole, as modifiers of rat hepatic monooxygenase activity.
Topics: Animals; Antifungal Agents; Fluconazole; Ketoconazole; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Substrate Specificity; Testosterone; Triazoles | 1988 |
Activities of fluconazole (UK 49,858) and ketoconazole against ketoconazole-susceptible and -resistant Candida albicans.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Drug Resistance, Microbial; Fluconazole; Ketoconazole; Rabbits; Triazoles | 1988 |
In vitro effects of fluconazole (UK-49,858) and ketoconazole on mouse lymphocyte proliferation and on Candida blastospore destruction by human polymorphonuclear leukocytes.
Topics: Animals; Antifungal Agents; Candida albicans; Cytotoxicity, Immunologic; Fluconazole; Humans; In Vitro Techniques; Ketoconazole; Lymphocyte Activation; Mice; Mice, Inbred Strains; Neutrophils; Spores, Fungal; Triazoles | 1988 |
Primary cutaneous phaeohyphomycosis. Report of three cases.
Topics: Adult; Aged; Aged, 80 and over; Dermatomycoses; Female; Fluconazole; Humans; Immune Tolerance; Ketoconazole; Male; Triazoles | 1988 |
[New antiparasitic drugs].
Topics: Amebicides; Anthelmintics; Antifungal Agents; Antimalarials; Artemisinins; Fluconazole; Humans; Itraconazole; Ketoconazole; Mefloquine; Phenanthrenes; Quinolines; Sesquiterpenes; Triazoles | 1988 |
Use of fluconazole in a patient with documented malabsorption of ketoconazole.
Topics: Administration, Oral; Adult; Antifungal Agents; Candidiasis; Candidiasis, Chronic Mucocutaneous; Female; Fluconazole; Humans; Intestinal Absorption; Ketoconazole; Triazoles | 1988 |
Improved method for azole antifungal susceptibility testing.
Topics: Antifungal Agents; Azoles; Fluconazole; Fungi; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Triazoles | 1988 |
Effects of antimycotic azoles on growth and sterol biosynthesis of Leishmania promastigotes.
Topics: Animals; Antifungal Agents; Chemical Phenomena; Chemistry; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Fluconazole; Gas Chromatography-Mass Spectrometry; Itraconazole; Ketoconazole; Leishmania; Leishmania braziliensis; Leishmania donovani; Leishmania mexicana; Leishmania tropica; Sterols; Triazoles | 1988 |
Effects of two oral antimycotics, ketoconazole and fluconazole, upon steroidogenesis in rat adrenal cells in vitro.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antifungal Agents; Cells, Cultured; Dose-Response Relationship, Drug; Fluconazole; Ketoconazole; Male; Pregnenolone; Rats; Rats, Inbred Strains; Steroids; Triazoles | 1988 |
Effects of azole antifungals in vitro on host/parasite interactions relevant to Candida infections.
Topics: Antifungal Agents; Candida albicans; Cell Adhesion; Clotrimazole; Female; Fluconazole; Humans; Imidazoles; In Vitro Techniques; Ketoconazole; Neutrophils; Phagocytosis; Triazoles; Vagina | 1988 |
Activity of triazole derivatives against Pityrosporum orbiculare in vitro and in vivo.
Topics: Animals; Antifungal Agents; Fluconazole; Itraconazole; Ketoconazole; Malassezia; Rabbits; Structure-Activity Relationship; Tinea Versicolor; Triazoles | 1988 |
The new generation of antifungal drugs.
Topics: Antifungal Agents; Echinocandins; Fluconazole; Humans; Itraconazole; Ketoconazole; Naphthalenes; Peptides; Peptides, Cyclic; Terbinafine; Triazoles | 1988 |
Efficacies of four antifungal agents in experimental murine sporotrichosis.
Topics: Amphotericin B; Animals; Antifungal Agents; Drug Evaluation, Preclinical; Itraconazole; Ketoconazole; Mice; Naphthalenes; Sporothrix; Sporotrichosis; Terbinafine; Triazoles | 1988 |
[Experimental renal infection with Aspergillus fumigatus in mice: a chemotherapeutic model of an organic mycosis].
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Disease Models, Animal; Female; Flucytosine; Itraconazole; Ketoconazole; Kidney Diseases; Mice; Mice, Inbred Strains; Miconazole; Triazoles | 1985 |
Activity of UK-49,858, a bis-triazole derivative, against experimental infections with Candida albicans and Trichophyton mentagrophytes.
Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Candidiasis, Vulvovaginal; Dermatomycoses; Female; Fluconazole; Guinea Pigs; Immunosuppression Therapy; Ketoconazole; Mice; Rats; Rats, Inbred Strains; Tinea; Triazoles | 1985 |
Penetration of imidazoles and triazoles into cerebrospinal fluid of rabbits.
Topics: Animals; Antifungal Agents; Fluconazole; Itraconazole; Ketoconazole; Meningitis, Haemophilus; Rabbits; Triazoles | 1985 |
Effects of imidazole- and triazole-derivative antifungal compounds on the growth and morphological development of Candida albicans hyphae.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Clotrimazole; Flucytosine; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Triazoles | 1985 |
Efficacy of UK-49,858 (fluconazole) against Candida albicans experimental infections in mice.
Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Female; Fluconazole; Immune Tolerance; Intestinal Diseases; Ketoconazole; Kinetics; Mice; Triazoles | 1985 |
Comparison of itraconazole and fluconazole in treatment of cryptococcal meningitis and candida pyelonephritis in rabbits.
Topics: Animals; Candidiasis; Cortisone; Cryptococcosis; Dose-Response Relationship, Drug; Fluconazole; Immunity; Itraconazole; Ketoconazole; Meningitis; Pyelonephritis; Rabbits; Triazoles | 1986 |
New and prospective developments in antifungal drugs.
Topics: Administration, Oral; Administration, Topical; Allylamine; Antifungal Agents; Clotrimazole; Dermatomycoses; Drug Compounding; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Naphthalenes; Terbinafine; Triazoles | 1986 |
Treatment of murine coccidioidal meningitis with fluconazole (UK 49,858).
Topics: Amphotericin B; Animals; Antifungal Agents; Coccidioides; Coccidioidomycosis; Fluconazole; Ketoconazole; Male; Meningitis; Mice; Mice, Inbred ICR; Triazoles | 1986 |
Azole resistance in Candida albicans.
Topics: Adult; Animals; Antifungal Agents; Candida albicans; Candidiasis; Candidiasis, Chronic Mucocutaneous; Disease Models, Animal; Drug Resistance, Microbial; Econazole; Female; Fluconazole; Guinea Pigs; Humans; Imidazoles; Itraconazole; Ketoconazole; Male; Mice; Miconazole; Rats; Rats, Inbred Strains; Triazoles | 1986 |
Cryptococcus neoformans: comparisons of in vitro antifungal susceptibilities of serotypes AD and BC.
Topics: Amphotericin B; Antifungal Agents; Cryptococcus; Cryptococcus neoformans; Flucytosine; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Nystatin; Serotyping; Triazoles | 1986 |
A diffusion chamber technique for testing of antifungal drugs against Sporothrix schenckii in vivo.
Topics: Amphotericin B; Animals; Antifungal Agents; Disease Models, Animal; Female; Itraconazole; Ketoconazole; Mice; Potassium Iodide; Sporothrix; Sporotrichosis; Triazoles | 1986 |
Treatment of cryptococcal meningitis in mice with fluconazole.
Topics: Amphotericin B; Animals; Antifungal Agents; Cryptococcosis; Fluconazole; Ketoconazole; Kinetics; Meningitis; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Rats; Rats, Inbred Strains; Triazoles | 1986 |
Treatment of murine histoplasmosis with UK 49,858 (fluconazole).
Topics: Animals; Antifungal Agents; Female; Fluconazole; Histoplasmosis; Ketoconazole; Lung Diseases, Fungal; Male; Mice; Mice, Inbred ICR; Mice, Nude; Triazoles | 1986 |
Activity of fluconazole (UK 49,858) and ketoconazole against Candida albicans in vitro and in vivo.
Topics: Animals; Antifungal Agents; Buffers; Candida albicans; Culture Media; Fluconazole; Fungal Proteins; Hydrogen-Ion Concentration; Ketoconazole; Male; Microbial Sensitivity Tests; Rats; Rats, Inbred Strains; Triazoles | 1986 |
Penetration of new azole compounds into the eye and efficacy in experimental Candida endophthalmitis.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Endophthalmitis; Eye; Fluconazole; Itraconazole; Ketoconazole; Kinetics; Male; Rabbits; Tissue Distribution; Triazoles | 1987 |
Action of fluconazole (UK-49,858) in relation to other systemic antifungal azoles.
Topics: Antifungal Agents; Candida; Candida albicans; Fluconazole; Ketoconazole; Miconazole; Triazoles | 1987 |
Fungistatic and fungicidal effects of amphotericin B, ketoconazole and fluconazole (UK 49,858) against histoplasma capsulatum in vitro and in vivo.
Topics: Amphotericin B; Animals; Antifungal Agents; Culture Techniques; Fluconazole; Histoplasma; Histoplasmosis; Ketoconazole; Male; Mice; Triazoles | 1987 |
Efficacy of fluconazole (UK-49,858) against experimental aspergillosis and cryptococcosis in mice.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus flavus; Aspergillus fumigatus; Brain Diseases; Cryptococcosis; Female; Fluconazole; Ketoconazole; Lung Diseases, Fungal; Mice; Opportunistic Infections; Triazoles | 1987 |
Effects of bifonazole, fluconazole, itraconazole, and terbinafine on the chemiluminescence response of immune cells.
Topics: Animals; Antifungal Agents; Cell Survival; Centrifugation; Fluconazole; Imidazoles; In Vitro Techniques; Itraconazole; Ketoconazole; Luminescent Measurements; Luminol; Mice; Mice, Inbred BALB C; Naphthalenes; Phagocytes; Rabbits; Rifampin; Spleen; Terbinafine; Triazoles | 1987 |
[Comparative action of 8 azole derivatives against Candida albicans: fungistatic action and cytologic study by scanning electron microscopy].
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Cytoplasm; Econazole; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Spheroplasts; Triazoles | 1988 |
In vitro assessment of antifungal drug resistance.
Topics: Antifungal Agents; Clotrimazole; Drug Resistance, Microbial; Fungi; Griseofulvin; Imidazoles; In Vitro Techniques; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Triazoles | 1986 |
Irrelevance of growth phase with respect to the Bay n 7133 and ICI 153,066 susceptibilities of Candida albicans.
Topics: Anti-Bacterial Agents; Candida albicans; In Vitro Techniques; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Triazoles | 1986 |
Serum fungistatic and fungicidal activity in volunteers receiving antifungal agents.
Topics: Aspergillus fumigatus; Candida; Candida albicans; Chromatography, High Pressure Liquid; Cryptococcus neoformans; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Humans; Ketoconazole; Mucorales; Mycoses; Rifampin; Triazoles | 1986 |
Influence of culture medium on susceptibility testing with BAY n 7133 and ketoconazole.
Topics: Antifungal Agents; Candida; Candida albicans; Cryptococcus; Cryptococcus neoformans; Culture Media; Humans; Ketoconazole; Microbial Sensitivity Tests; Triazoles | 1986 |
In vitro sensitivity of environmental isolates of pathogenic dematiaceous fungi to azole compounds and a phenylpropyl-morpholine derivative.
Topics: Animals; Antifungal Agents; Culture Media; Econazole; Fungi; Imidazoles; Ketoconazole; Mice; Miconazole; Microbial Sensitivity Tests; Morpholines; Thiabendazole; Triazoles | 1987 |
Study of current and new drugs in a murine model of acute paracoccidioidomycosis.
Topics: Amphotericin B; Animals; Imidazoles; Ketoconazole; Lung; Male; Mice; Mice, Inbred BALB C; Paracoccidioides; Paracoccidioidomycosis; Spleen; Triazoles | 1985 |
New azole compounds: vibunazole (Bay n7133) and Bay L9139, compared with ketoconazole in the therapy of systemic candidosis and in pharmacokinetic studies, in mice.
Topics: Animals; Antifungal Agents; Candidiasis; Imidazoles; Ketoconazole; Kinetics; Mice; Triazoles | 1985 |
Activities of the modified polyene N-D-ornithyl amphotericin methyl ester and the azoles ICI 153066, Bay n 7133, and Bay l 9139 compared with those of amphotericin B and ketoconazole in the therapy of experimental blastomycosis.
Topics: Amphotericin B; Animals; Antifungal Agents; Blastomycosis; Imidazoles; Ketoconazole; Male; Mice; Mice, Inbred BALB C; Time Factors; Triazoles | 1985 |
Activity of BAY n 7133 and BAY 1 9139 in vitro and in experimental murine coccidioidomycosis.
Topics: Animals; Antifungal Agents; Coccidioides; Coccidioidomycosis; Imidazoles; Ketoconazole; Mice; Triazoles | 1985 |
In vitro susceptibility testing of Naegleria fowleri to ketoconazole, BAYn7133, and allopurinol riboside.
Topics: Allopurinol; Amoeba; Amphotericin B; Animals; Antiprotozoal Agents; Ketoconazole; Microbial Sensitivity Tests; Ribonucleosides; Triazoles | 1984 |
In vitro studies with R 51,211 (itraconazole).
Topics: Antifungal Agents; Fungi; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Morpholines; Triazoles | 1984 |
Antifungal relative inhibition factors: BAY l-9139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 14-4767/002, sulconazole, terconazole and vibunazole (BAY n-7133) compared in vitro with nine established antifungal agents.
Topics: Antifungal Agents; Aspergillus; Candida; Clotrimazole; Econazole; Imidazoles; In Vitro Techniques; Itraconazole; Ketoconazole; Miconazole; Morpholines; Triazoles | 1984 |
Antimycotic therapy of experimental infections caused by dematiaceous fungi.
Topics: Amphotericin B; Animals; Antifungal Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Flucytosine; Fluorouracil; Humans; Ketoconazole; Male; Mice; Mitosporic Fungi; Mycoses; Triazoles | 1984 |
In-vitro studies of a new oral azole antimycotic, BAY N 7133.
Topics: Antifungal Agents; Culture Media; Drug Resistance, Microbial; Fungi; Hydrogen-Ion Concentration; Imidazoles; Ketoconazole; Microbial Sensitivity Tests; Piperazines; Triazoles | 1983 |
Treatment of experimental murine aspergillosis with BAY n7133.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Female; Ketoconazole; Lung; Male; Mice; Mice, Inbred BALB C; Triazoles | 1983 |
In-vitro inhibitory activities of 2 new orally absorbable imidazole derivatives: BAY n 7133 and BAY 1 9139.
Topics: Antifungal Agents; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Fungi; Imidazoles; Ketoconazole; Miconazole; Species Specificity; Triazoles | 1983 |
Comparison of ketoconazole, Bay N7133, and Bay L9139 in the treatment of experimental vaginal candidiasis.
Topics: Animals; Antifungal Agents; Candidiasis, Vulvovaginal; Female; Imidazoles; Ketoconazole; Rats; Rats, Inbred Strains; Triazoles | 1983 |
Comparative activities of Bay n7133, ICI 153,066, and ketoconazole in murine cryptococcosis.
Topics: Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Female; Ketoconazole; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Triazoles | 1983 |
[Microbiological determination of the oral antifungal agent Bay N 7133 and ketoconazole in cervical and vaginal secretion of patients].
Topics: Administration, Oral; Adult; Antifungal Agents; Biological Assay; Candida; Candidiasis, Vulvovaginal; Cervix Mucus; Female; Humans; Ketoconazole; Leukorrhea; Triazoles | 1983 |
[Correlation of in vitro and in vivo actions of azole antimycotics].
Topics: Animals; Antifungal Agents; Candidiasis; Flucytosine; In Vitro Techniques; Ketoconazole; Male; Mice; Mice, Inbred Strains; Triazoles | 1984 |
A direct comparison of oral treatments with BAY-n-7133, BAY-1-9139 and ketoconazole in experimental murine coccidioidomycosis.
Topics: Administration, Oral; Animals; Antifungal Agents; Chemical Phenomena; Chemistry; Coccidioides; Coccidioidomycosis; Drug Evaluation, Preclinical; Female; Imidazoles; Ketoconazole; Mice; Spores, Fungal; Triazoles | 1984 |
Azole resistance in Candida albicans.
Topics: Amino Acids; Animals; Antifungal Agents; Candida albicans; Candidiasis, Chronic Mucocutaneous; Candidiasis, Vulvovaginal; Drug Resistance, Microbial; Ergosterol; Female; Ketoconazole; Mice; Rats; Triazoles | 1984 |
In-vitro studies with four new antifungal agents: BAY n 7133, bifonazole (BAY h 4502), ICI 153,066 and Ro 14-4767/002.
Topics: Antifungal Agents; Arthrodermataceae; Blastomyces; Candida; Coccidioides; Cryptococcus neoformans; Drug Evaluation, Preclinical; Histoplasma; Imidazoles; Ketoconazole; Miconazole; Morpholines; Sporothrix; Triazoles | 1984 |
In vitro activities of amphotericin B in combination with four antifungal agents and rifampin against Aspergillus spp.
Topics: Amphotericin B; Antifungal Agents; Aspergillus; Flucytosine; Ketoconazole; Microbial Sensitivity Tests; Rifampin; Triazoles | 1984 |
Antimycotic activity of BAY N 7133 in animal experiments.
Topics: Administration, Oral; Administration, Topical; Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Cryptococcosis; Female; Flucytosine; Guinea Pigs; Hair; Infusions, Parenteral; Ketoconazole; Male; Mice; Mycoses; Triazoles | 1984 |
Antimycotic azoles. 7. Synthesis and antifungal properties of a series of novel triazol-3-ones.
Topics: Animals; Antifungal Agents; Aspergillus fumigatus; Candida; Candidiasis, Vulvovaginal; Cryptococcus neoformans; Dermatomycoses; Female; Guinea Pigs; Itraconazole; Ketoconazole; Microsporum; Phialophora; Rats; Rats, Inbred Strains; Sporothrix; Triazoles; Trichophyton | 1984 |
In vitro antifungal activities of Bay n 7133 and Bay L 9139, two new orally absorbed antifungal imidazole derivatives, against pathogenic yeasts.
Topics: Antifungal Agents; Candida; Candida albicans; Cryptococcus; Cryptococcus neoformans; Culture Media; Echinocandins; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Peptides; Peptides, Cyclic; Triazoles | 1984 |
Resistance to azole drugs in Neurospora crassa.
Topics: Antifungal Agents; Crosses, Genetic; Drug Resistance, Microbial; Fluconazole; Ketoconazole; Meiosis; Mutagenesis; Neurospora crassa; Selection, Genetic; Triazoles | 1995 |
Functional expression of Saccharomyces cerevisiae CYP51A1 encoding lanosterol-14-demethylase in tobacco results in bypass of endogenous sterol biosynthetic pathway and resistance to an obtusifoliol-14-demethylase herbicide inhibitor.
Topics: Cholestadienols; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance; Fungal Proteins; Herbicides; Itraconazole; Ketoconazole; Nicotiana; Oxidoreductases; Plants, Genetically Modified; Plants, Toxic; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Silanes; Sterol 14-Demethylase; Sterols; Triazoles | 1995 |
In vitro activity of D0870 compared with those of other azoles against fluconazole-resistant Candida spp.
Topics: Antifungal Agents; Candida; Drug Resistance, Microbial; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Triazoles | 1995 |
Disposition of azole antifungal agents. II. Hepatic binding and clearance of dichlorophenyl-bis-triazolylpropanol (DTP) in the rat.
Topics: Animals; Antifungal Agents; Azoles; Binding Sites; Cytochrome P-450 Enzyme System; Ketoconazole; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Triazoles | 1994 |
Pneumocystis carinii is resistant to imidazole antifungal agents.
Topics: Animals; Antifungal Agents; Ergosterol; Female; Fluconazole; Gas Chromatography-Mass Spectrometry; Itraconazole; Ketoconazole; Miconazole; Pneumocystis; Rats; Rats, Sprague-Dawley; Triazoles | 1994 |
[Cross-resistance of Candida albicans to several different families of antifungals with ergosterol biosynthesis-inhibiting activity].
Topics: Antifungal Agents; Candida albicans; Depression, Chemical; Drug Resistance, Microbial; Ergosterol; Ketoconazole; Morpholines; Naphthalenes; Terbinafine; Triazoles | 1994 |
Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas' disease.
Topics: Animals; Antifungal Agents; Chagas Disease; Disease Models, Animal; Ergosterol; Female; Ketoconazole; Mice; Naphthalenes; Terbinafine; Triazoles; Trypanocidal Agents | 1993 |
Cure of short- and long-term experimental Chagas' disease using D0870.
Topics: Animals; Base Sequence; Chagas Disease; Drug Administration Schedule; Ketoconazole; Molecular Sequence Data; Nifurtimox; Sterols; Time Factors; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 1996 |
Naturally azole-resistant Leishmania braziliensis promastigotes are rendered susceptible in the presence of terbinafine: comparative study with azole-susceptible Leishmania mexicana promastigotes.
Topics: Animals; Antifungal Agents; Azoles; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Drug Resistance; Enzyme Inhibitors; Ketoconazole; Leishmania braziliensis; Leishmania mexicana; Naphthalenes; Oxidoreductases; Squalene; Sterol 14-Demethylase; Sterols; Terbinafine; Triazoles | 1996 |
Novel 17-azolyl steroids, potent inhibitors of human cytochrome 17 alpha-hydroxylase-C17,20-lyase (P450(17) alpha): potential agents for the treatment of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androstadienes; Animals; Antineoplastic Agents; Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Male; Microsomes; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Testis; Triazoles; Tumor Cells, Cultured | 1998 |
Voriconazole against fluconazole-susceptible and resistant candida isolates: in-vitro efficacy compared with that of itraconazole and ketoconazole.
Topics: Antifungal Agents; Candida; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole | 1998 |
Differential regulation of gonadotropin secretion by testosterone in the human male: absence of a negative feedback effect of testosterone on follicle-stimulating hormone secretion.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Dexamethasone; Enzyme Inhibitors; Estrogen Antagonists; Feedback; Follicle Stimulating Hormone; Glucocorticoids; Gonadal Steroid Hormones; Gonadotropins; Humans; Ketoconazole; Luteinizing Hormone; Male; Nitriles; Testosterone; Triazoles | 2001 |
Application of capillary zone electrophoresis with off-line solid-phase extraction to in vitro metabolism studies of antifungals.
Topics: Acetic Acid; Acetonitriles; Antifungal Agents; Clotrimazole; Drug Stability; Electrophoresis, Capillary; Fluconazole; Humans; Itraconazole; Ketoconazole; Methanol; Microsomes, Liver; Molecular Structure; Molecular Weight; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Solvents; Triazoles; Verapamil; Voriconazole | 2001 |
[Synthesis and antifungal activity of 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted-2-propanols].
Topics: Antifungal Agents; Candida albicans; Fluconazole; Ketoconazole; Microbial Sensitivity Tests; Microsporum; Saccharomyces; Structure-Activity Relationship; Triazoles | 1997 |
Human CYP3A4 and the metabolism of nefazodone and hydroxynefazodone by human liver microsomes and heterologously expressed enzymes.
Topics: Animals; Antidepressive Agents, Second-Generation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Inhibitors; Humans; Insecta; Ketoconazole; Microsomes, Liver; Mixed Function Oxygenases; Piperazines; Transfection; Triazoles; Tumor Cells, Cultured | 2002 |
Synthesis of novel water soluble benzylazolium prodrugs of lipophilic azole antifungals.
Topics: Animals; Antifungal Agents; Aspergillus fumigatus; Azoles; Candida albicans; Candidiasis; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Prodrugs; Rats; Solubility; Thiazoles; Triazoles | 2002 |
Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Oxidation-Reduction; Pyrimidines; Quinidine; Sulfaphenazole; Theophylline; Triazoles; Voriconazole | 2003 |
In vitro susceptibilities of Malassezia species to a new triazole, albaconazole (UR-9825), and other antifungal compounds.
Topics: Antifungal Agents; Drug Resistance, Fungal; Fluconazole; Flucytosine; In Vitro Techniques; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Pyrimidines; Quinazolines; Triazoles; Voriconazole | 2003 |
Retinoic acid metabolism inhibition by 3-azolylmethyl-1H-indoles and 2, 3 or 5-(alpha-azolylbenzyl)-1H-indoles.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Hydroxylation; In Vitro Techniques; Indoles; Ketoconazole; Microsomes, Liver; Molecular Structure; Rats; Structure-Activity Relationship; Tretinoin; Triazoles | 2003 |
Multiple mechanisms account for variation in base-line sensitivity to azole fungicides in field isolates of Mycosphaerella graminicola.
Topics: Ascomycota; ATP-Binding Cassette Transporters; Azoles; Carbon Radioisotopes; Crosses, Genetic; Cytochrome P-450 Enzyme System; Fungal Proteins; Fungicides, Industrial; Gene Expression Regulation, Fungal; Ketoconazole; Microbial Sensitivity Tests; Triazoles | 2003 |
Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible.
Topics: Anti-Infective Agents; Bridged-Ring Compounds; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluorometry; Humans; In Vitro Techniques; Ketoconazole; Microsomes, Liver; NADP; Pleurotus; Solubility; Steroid Hydroxylases; Substrate Specificity; Triazoles; Xenobiotics | 2004 |
In vitro and in vivo activities of the novel azole antifungal agent r126638.
Topics: Animals; Antifungal Agents; Candida; Dermatomycoses; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Itraconazole; Ketoconazole; Mice; Microbial Sensitivity Tests; Microsporidia; Skin; Tinea; Triazoles; Trichophyton | 2004 |
DNA fingerprinting pattern and susceptibility to antifungal drugs in Cryptococcus neoformans variety grubii isolates from Barcelona city and rural environmental samples.
Topics: Amphotericin B; Antifungal Agents; Cryptococcus neoformans; DNA Fingerprinting; DNA, Fungal; Drug Resistance, Fungal; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Soil Microbiology; Spain; Triazoles; Voriconazole | 2005 |
Enantiomeric separation of ketoconazole and terconazole antifungals by electrokinetic chromatography: Rapid quantitative analysis of ketoconazole in pharmaceutical formulations.
Topics: Antifungal Agents; Buffers; Chromatography; Cyclodextrins; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Ketoconazole; Stereoisomerism; Temperature; Triazoles | 2005 |
In vitro susceptibility of oral Candida to seven antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candida tropicalis; Candidiasis, Oral; Drug Resistance, Fungal; Fluconazole; Humans; Itraconazole; Ketoconazole; Miconazole; Mouth Diseases; Nystatin; Pyrimidines; Triazoles; Voriconazole | 2005 |
Cytoskeleton reassembly in cardiomyocytes infected by Trypanosoma cruzi is triggered by treatment with ergosterol biosynthesis inhibitors.
Topics: Animals; Cells, Cultured; Cytoskeleton; Ergosterol; Ketoconazole; Mice; Myocytes, Cardiac; Myofibrils; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 2006 |
In vitro activity of R126638 and ketoconazole against Malassezia species.
Topics: Antifungal Agents; Epidermis; Humans; Imidazoles; In Vitro Techniques; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Triazoles | 2006 |
A modified Christensen's urea and CLSI broth microdilution method for testing susceptibilities of six Malassezia species to voriconazole, itraconazole, and ketoconazole.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Culture Media; Dermatomycoses; HIV Infections; Humans; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Polysorbates; Pyrimidines; Triazoles; Urea; Voriconazole | 2006 |
Antifungal susceptibilities of the species of the Pseudallescheria boydii complex.
Topics: Amphotericin B; Antifungal Agents; Candida; Drug Resistance, Fungal; Echinocandins; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Lipopeptides; Lipoproteins; Micafungin; Microbial Sensitivity Tests; Naphthalenes; Peptides, Cyclic; Pseudallescheria; Pyrimidines; Quality Control; Quinazolines; Scedosporium; Terbinafine; Thiazoles; Triazoles; Voriconazole | 2006 |
MgMfs1, a major facilitator superfamily transporter from the fungal wheat pathogen Mycosphaerella graminicola, is a strong protectant against natural toxic compounds and fungicides.
Topics: Antifungal Agents; Ascomycota; Drug Resistance, Multiple, Fungal; Expressed Sequence Tags; Fungal Proteins; Fungicides, Industrial; Genes, Fungal; Ketoconazole; Membrane Transport Proteins; Miconazole; Microbial Sensitivity Tests; Models, Biological; Mutation; Perylene; Saccharomyces cerevisiae; Triazoles; Triticum | 2007 |
Antifungal activities of azole agents against the Malassezia species.
Topics: Antifungal Agents; Azoles; Fluconazole; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Pyrimidines; Tinea Versicolor; Triazoles; Voriconazole | 2007 |
Antifungal susceptibility testing of Trichophyton rubrum by E-test.
Topics: Antifungal Agents; Cells, Cultured; Drug Resistance, Fungal; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Tinea; Triazoles; Trichophyton; Voriconazole | 2007 |
[Acanthamoeba keratitis: about the first two Tunisian cases].
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Amebicides; Animals; Antifungal Agents; Benzamidines; Biguanides; Contact Lenses, Hydrophilic; Drug Therapy, Combination; Eye Infections, Fungal; Female; Fusarium; Humans; Keratoplasty, Penetrating; Ketoconazole; Pyrimidines; Triazoles; Tunisia; Voriconazole | 2007 |
In vitro susceptibility of Sporothrix schenckii to six antifungal agents determined using three different methods.
Topics: Amphotericin B; Antifungal Agents; Fluconazole; Flucytosine; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Quality Control; Sporothrix; Sporotrichosis; Triazoles; Voriconazole | 2007 |
In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Caspofungin; Echinocandins; Fluconazole; Flucytosine; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Mucormycosis; Peptides, Cyclic; Pyrimidines; Triazoles; Voriconazole | 2007 |
Interactions of azole antifungal agents with the human breast cancer resistance protein (BCRP).
Topics: Antifungal Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Survival; Chlorophyll; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Flow Cytometry; Fluconazole; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Itraconazole; Ketoconazole; Neoplasm Proteins; Pyrimidines; Topotecan; Transfection; Triazoles; Voriconazole | 2007 |
Identification of human liver cytochrome P450 enzymes involved in biotransformation of vicriviroc, a CCR5 receptor antagonist.
Topics: Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Biotransformation; Bridged-Ring Compounds; Carboxylic Acids; CCR5 Receptor Antagonists; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Inhibitors; Humans; Immunologic Factors; In Vitro Techniques; Isoenzymes; Ketoconazole; Kinetics; Liver; Oxidation-Reduction; Piperazines; Pyrimidines; Recombinant Proteins; Substrate Specificity; Testosterone; Triazoles | 2007 |
Activity of caspofungin and voriconazole against clinical isolates of Candida and other medically important yeasts by the CLSI M-44A disk diffusion method with Neo-Sensitabs tablets.
Topics: Amphotericin B; Antifungal Agents; Candida; Caspofungin; Cryptococcus; Disk Diffusion Antimicrobial Tests; Drug Resistance, Fungal; Echinocandins; Fluconazole; Itraconazole; Ketoconazole; Lipopeptides; Pyrimidines; Rhodotorula; Triazoles; Trichosporon; Voriconazole | 2008 |
Maraviroc: in vitro assessment of drug-drug interaction potential.
Topics: Area Under Curve; Atazanavir Sulfate; Cyclohexanes; Cytochrome P-450 CYP3A; Drug Interactions; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Ketoconazole; Liver; Male; Maraviroc; Microsomes, Liver; Oligopeptides; Predictive Value of Tests; Pyridines; Ritonavir; Saquinavir; Triazoles | 2008 |
Comparison of the anti-inflammatory activities of imidazole antimycotics in relation to molecular structure.
Topics: Anti-Inflammatory Agents; Antifungal Agents; Cells, Cultured; Fluconazole; Humans; Imidazoles; Itraconazole; Ketoconazole; Leukotriene B4; Molecular Structure; Neutrophils; Platelet Activating Factor; Pyrimidines; Triazoles; Voriconazole | 2008 |
CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells-comparison with other conazole pesticides.
Topics: Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caco-2 Cells; Calcitriol; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Food Contamination; Fungicides, Industrial; Glutathione Transferase; Humans; Imidazoles; Intestinal Mucosa; Ketoconazole; Kinetics; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger; Spectrophotometry, Ultraviolet; Triazoles | 2009 |
Susceptibility to voriconazole, fluconazole, and ketoconazole of yeast isolated from patients with hematological malignancies.
Topics: Antifungal Agents; Candida; Candidiasis; Drug Resistance, Fungal; Fluconazole; Hematologic Neoplasms; Humans; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole | 2008 |
Steroidogenesis-disrupting compounds can be effectively studied for major fertility-related endpoints using in vitro cultured mouse follicles.
Topics: Aminoglutethimide; Animals; Animals, Newborn; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; In Vitro Techniques; Ketoconazole; Mice; Mice, Inbred Strains; Ovarian Follicle; Sensitivity and Specificity; Steroids; Toxicity Tests; Triazoles | 2009 |
Curcumin modulates efflux mediated by yeast ABC multidrug transporters and is synergistic with antifungals.
Topics: Anisomycin; Antifungal Agents; Biological Transport; Candida albicans; Curcumin; Cycloheximide; Drug Synergism; Enzyme Inhibitors; Fluconazole; Itraconazole; Ketoconazole; Methotrexate; Miconazole; Multidrug Resistance-Associated Proteins; Pyrimidines; Rhodamines; Saccharomyces cerevisiae; Triazoles; Voriconazole | 2009 |
In vitro synergistic effects of antituberculous drugs plus antifungals against Coccidioides posadasii.
Topics: Amphotericin B; Antifungal Agents; Antitubercular Agents; Caspofungin; Coccidioides; Coccidioidomycosis; Drug Synergism; Echinocandins; Ethambutol; Fluconazole; Humans; Isoniazid; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Pyrazinamide; Pyrimidines; Triazoles; Voriconazole | 2009 |
Direct antifungal susceptibility testing of positive Candida blood cultures by sensititre YeastOne.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Drug Resistance, Fungal; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Reagent Kits, Diagnostic; Sensitivity and Specificity; Time Factors; Triazoles; Voriconazole | 2009 |
Simultaneous determination of five systemic azoles in plasma by high-performance liquid chromatography with ultraviolet detection.
Topics: Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Fluconazole; Humans; Itraconazole; Ketoconazole; Pyrimidines; Quality Control; Reproducibility of Results; Spectrophotometry, Ultraviolet; Time Factors; Triazoles; Ultraviolet Rays; Voriconazole | 2009 |
About the role of enantioselective selector-selectand interactions and the mobilities of diastereomeric associates in enantiomer separations using CE.
Topics: Chromatography, High Pressure Liquid; Cyclodextrins; Electrophoresis, Capillary; Ketoconazole; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Triazoles | 2009 |
In vitro response of cutaneous mycosis fungal agents to the most widely used systemic antifungals in dermatology.
Topics: Antifungal Agents; Dermatomycoses; Humans; Ketoconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Naphthalenes; Terbinafine; Triazoles | 2009 |
Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes.
Topics: Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Cross-Linking Reagents; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Genotype; Humans; Ketoconazole; Letrozole; Methoxsalen; Microsomes, Liver; Nitriles; Oxidoreductases; Steroid Hydroxylases; Triazoles | 2009 |
Azole binding properties of Candida albicans sterol 14-alpha demethylase (CaCYP51).
Topics: Antifungal Agents; Azoles; Candida albicans; Econazole; Fluconazole; Itraconazole; Ketoconazole; Miconazole; Protein Binding; Pyrimidines; Sterol 14-Demethylase; Triazoles; Voriconazole | 2010 |
Identification and characterization of four azole-resistant erg3 mutants of Candida albicans.
Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Ergosterol; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mutation; Oxidoreductases; Pyrimidines; Triazoles; Voriconazole | 2010 |
In vitro susceptibility of Madurella mycetomatis to posaconazole and terbinafine.
Topics: Antifungal Agents; Itraconazole; Ketoconazole; Madurella; Microbial Sensitivity Tests; Naphthalenes; Terbinafine; Triazoles | 2011 |
Determination of metabolic profile of anti-malarial trioxane CDRI 99/411 in rat liver microsomes using HPLC.
Topics: Animals; Antimalarials; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Heterocyclic Compounds; Humans; Ketoconazole; Kinetics; Male; Metabolome; Microsomes, Liver; Nonlinear Dynamics; Rats; Rats, Sprague-Dawley; Spiro Compounds; Triazoles | 2012 |
Hepatic cytochrome P450s attenuate the cytotoxicity induced by leflunomide and its active metabolite A77 1726 in primary cultured rat hepatocytes.
Topics: Aniline Compounds; Animals; Benzoflavones; Biomarkers; Cell Survival; Cells, Cultured; Crotonates; Cytochrome P-450 Enzyme System; Hepatocytes; Hydroxybutyrates; Inactivation, Metabolic; Isoxazoles; Ketoconazole; Leflunomide; Liver; Male; Nitriles; Primary Cell Culture; Proadifen; Rats; Rats, Sprague-Dawley; Ticlopidine; Toluidines; Triazoles | 2011 |
In vitro susceptibility of fluconazole-susceptible and -resistant isolates of Malassezia pachydermatis against azoles.
Topics: Antifungal Agents; Drug Resistance, Fungal; Fluconazole; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole | 2011 |
Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4.
Topics: Adult; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Design; Enzyme Inhibitors; Erythromycin; Female; Hepatocytes; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Ketoconazole; Male; Middle Aged; Time Factors; Triazoles; Young Adult | 2011 |
Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices.
Topics: Adenosine Triphosphate; Animals; Aspartate Aminotransferases; Benzopyrans; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glucuronides; Glutathione; Hydroxylation; Ketoconazole; L-Lactate Dehydrogenase; Liver; Male; Mass Spectrometry; Molecular Structure; Necrosis; Rats; Rats, Sprague-Dawley; Sulfaphenazole; Tranylcypromine; Triazoles | 2011 |
Antifungal susceptibility and virulence attributes of bloodstream isolates of Candida from Hong Kong and Finland.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidemia; Caspofungin; Drug Resistance, Fungal; Echinocandins; Finland; Fluconazole; Flucytosine; Hemolysin Proteins; Hong Kong; Humans; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Peptide Hydrolases; Pyrimidines; Triazoles; Virulence Factors; Voriconazole | 2011 |
Evaluation of saliva flow rates, Candida colonization and susceptibility of Candida strains after head and neck radiation.
Topics: Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Candida; Candida albicans; Colony Count, Microbial; Dental Caries; Drug Resistance, Fungal; Female; Fluconazole; Head and Neck Neoplasms; Humans; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Mouth; Pyrimidines; Radiation Injuries; Saliva; Salivary Glands; Secretory Rate; Triazoles; Voriconazole; Xerostomia | 2012 |
In vitro antifungal susceptibility of Malassezia pachydermatis from dogs with and without skin lesions.
Topics: Animals; Antifungal Agents; Dermatomycoses; Dog Diseases; Dogs; Fluconazole; Itraconazole; Ketoconazole; Malassezia; Miconazole; Naphthalenes; Pyrimidines; Terbinafine; Triazoles; Voriconazole | 2012 |
Synthesis of novel brassinosteroid biosynthesis inhibitors based on the ketoconazole scaffold.
Topics: Arabidopsis; Brassinosteroids; Dioxolanes; Inhibitory Concentration 50; Ketoconazole; Molecular Structure; Structure-Activity Relationship; Triazoles | 2012 |
Fluconazole exposure rather than clonal spreading is correlated with the emergence of Candida glabrata with cross-resistance to triazole antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Candida glabrata; Caspofungin; Drug Resistance, Fungal; Echinocandins; Fluconazole; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole | 2012 |
Implication of free cholesterol in LC-MS response enhancement.
Topics: Animals; Cholesterol; Chromatography, Liquid; Cyclohexanols; Humans; Ketoconazole; Liquid-Liquid Extraction; Pharmaceutical Preparations; Plasma; Rats; Solid Phase Extraction; Tandem Mass Spectrometry; Triazoles; Tryptamines; Venlafaxine Hydrochloride | 2012 |
Mouse precision-cut liver slices as an ex vivo model to study idiosyncratic drug-induced liver injury.
Topics: Animals; Benzodiazepines; Biomarkers; Carbamazepine; Cell Survival; Chemical and Drug Induced Liver Injury; Chemokines; Chromans; Clozapine; Cytokines; Diclofenac; Drug Synergism; Female; Glutathione; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; In Vitro Techniques; Ketoconazole; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Nitrogen Oxides; Olanzapine; Pyrimidines; Thiazolidinediones; Triazoles; Troglitazone; Voriconazole | 2012 |
In vitro antifungal activity of isavuconazole against Madurella mycetomatis.
Topics: Antifungal Agents; Humans; Itraconazole; Ketoconazole; Madurella; Microbial Sensitivity Tests; Mycetoma; Nitriles; Pyridines; Triazoles | 2012 |
Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.
Topics: Animals; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Constitutive Androstane Receptor; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Gene Expression Regulation; Hepatocytes; Host Specificity; Humans; Ketoconazole; Liver; Membrane Proteins; Mice; Mice, Transgenic; Oxidoreductases, N-Demethylating; Pregnane X Receptor; Primary Cell Culture; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Species Specificity; Triazoles; Voriconazole | 2013 |
Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens.
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Escherichia coli; Fluconazole; Fungal Proteins; Humans; Itraconazole; Ketoconazole; Kinetics; Lanosterol; NADP; Protein Binding; Pyrimidines; Recombinant Proteins; Species Specificity; Sterol 14-Demethylase; Triazoles; Voriconazole | 2013 |
Differential pulse polarographic investigation of the antifungal drugs itraconazole, ketoconazole, fluconazole and voriconazole using a dropping mercury electrode.
Topics: Antifungal Agents; Electrochemistry; Electrodes; Fluconazole; Hydrogen-Ion Concentration; Indicators and Reagents; Itraconazole; Ketoconazole; Mercury; Polarography; Pyrimidines; Reference Standards; Reproducibility of Results; Triazoles; Voriconazole | 2012 |
Effects of cytochrome P450 inhibitors on peroxidase activity.
Topics: Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Ellipticines; Enzyme Activation; Enzyme Inhibitors; Horseradish Peroxidase; Humans; Ketoconazole; Metyrapone; Piperonyl Butoxide; Proadifen; Quinidine; Structure-Activity Relationship; Substrate Specificity; Sulfaphenazole; Triazoles; Troleandomycin | 2012 |
Voriconazole suppresses the growth of Leishmania species in vitro.
Topics: Animals; Antiprotozoal Agents; Fluconazole; Inhibitory Concentration 50; Ketoconazole; Leishmania; Parasitic Sensitivity Tests; Pyrimidines; Species Specificity; Triazoles; Voriconazole | 2013 |
Molecular identification and antifungal susceptibility of yeast isolates causing fungemia collected in a population-based study in Spain in 2010 and 2011.
Topics: Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candida tropicalis; Candidiasis; Drug Resistance, Fungal; Echinocandins; Fungemia; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Spain; Triazoles; Voriconazole | 2014 |
Studies on the antileishmanial mechanism of action of the arylimidamide DB766: azole interactions and role of CYP5122A1.
Topics: Amidines; Animals; Antiprotozoal Agents; Axenic Culture; Blotting, Western; Cricetinae; Drug Combinations; Drug Resistance; Drug Synergism; Furans; Gene Expression Regulation; Ketoconazole; Leishmania donovani; Life Cycle Stages; Mice; Phosphorylcholine; Protozoan Proteins; Sterol 14-Demethylase; Triazoles | 2014 |
Madurella mycetomatis is highly susceptible to ravuconazole.
Topics: Antifungal Agents; Itraconazole; Ketoconazole; Madurella; Microbial Sensitivity Tests; Thiazoles; Triazoles | 2014 |
Investigation of aromatase inhibitory activity of metal complexes of 8-hydroxyquinoline and uracil derivatives.
Topics: Aromatase Inhibitors; Cell Line; Coordination Complexes; Copper; Humans; Inhibitory Concentration 50; Ketoconazole; Letrozole; Lung; Manganese; Nickel; Nitriles; Oxyquinoline; Triazoles; Uracil | 2014 |
Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism.
Topics: Alanine Transaminase; Amiodarone; Animals; Chemical and Drug Induced Liver Injury; Dexamethasone; Gadolinium; Ketoconazole; Kupffer Cells; Male; Mice; Mice, Inbred BALB C; Models, Animal; Triazoles | 2016 |
In vitro activities of a wide panel of antifungal drugs against various Scopulariopsis and Microascus species.
Topics: Amphotericin B; Antifungal Agents; Ascomycota; Caspofungin; Drug Resistance, Fungal; Echinocandins; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Scopulariopsis; Triazoles; Voriconazole | 2015 |
Electrochemical behavior of the antifungal agents itraconazole, posaconazole and ketoconazole at a glassy carbon electrode.
Topics: Antifungal Agents; Carbon; Electrochemical Techniques; Electrochemistry; Electrodes; Indicators and Reagents; Itraconazole; Ketoconazole; Solutions; Triazoles | 2015 |
An in vitro biorelevant gastrointestinal transfer (BioGIT) system for forecasting concentrations in the fasted upper small intestine: Design, implementation, and evaluation.
Topics: Dipyridamole; Fasting; Gastric Mucosa; Gastrointestinal Tract; In Vitro Techniques; Intestine, Small; Ketoconazole; Models, Biological; Ranitidine; Triazoles | 2016 |
Predicting Fecundity of Fathead Minnows (Pimephales promelas) Exposed to Endocrine-Disrupting Chemicals Using a MATLAB®-Based Model of Oocyte Growth Dynamics.
Topics: Animals; Cell Proliferation; Cyprinidae; Endocrine Disruptors; Environmental Exposure; Fadrozole; Fertility; Imidazoles; Ketoconazole; Models, Biological; Oocytes; Reproduction; Trenbolone Acetate; Triazoles; Vitellogenins | 2016 |
Testotoxicosis: Report of Two Cases, One with a Novel Mutation in LHCGR Gene.
Topics: Anastrozole; Androgen Antagonists; Anilides; Aromatase Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Genetic Predisposition to Disease; Humans; Infant; Ketoconazole; Male; Mutation; Nitriles; Puberty, Precocious; Receptors, LH; Sequence Analysis, DNA; Testosterone; Tosyl Compounds; Triazoles | 2015 |
Differences in Food Effects for 2 Weak Bases With Similar BCS Drug-Related Properties: What Is Happening in the Intestinal Lumen?
Topics: Adolescent; Adult; Biopharmaceutics; Cell Membrane; Computer Simulation; Fasting; Female; Food-Drug Interactions; Gastric Emptying; Humans; Intestinal Absorption; Intestinal Mucosa; Ketoconazole; Male; Middle Aged; Triazoles; Young Adult | 2016 |
Assessment of Bioequivalence of Weak Base Formulations Under Various Dosing Conditions Using Physiologically Based Pharmacokinetic Simulations in Virtual Populations. Case Examples: Ketoconazole and Posaconazole.
Topics: Administration, Oral; Adult; Antifungal Agents; Carbonated Beverages; Computer Simulation; Fasting; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestine, Small; Ketoconazole; Models, Biological; Solubility; Therapeutic Equivalency; Triazoles | 2017 |
Triazoles inhibit cholesterol export from lysosomes by binding to NPC1.
Topics: Androstenes; Animals; Antifungal Agents; Binding Sites; Biological Transport; Carrier Proteins; Cell Line; CHO Cells; Cholesterol; Cricetulus; Endocytosis; Itraconazole; Ketoconazole; Lysosomes; Membrane Glycoproteins; Protein Binding; Protein Domains; Triazoles | 2017 |
Comparison of two in vitro antifungal sensitivity tests and monitoring during therapy of Sporothrix schenckii sensu stricto in Malaysian cats.
Topics: Amphotericin B; Animals; Antifungal Agents; Cat Diseases; Cats; In Vitro Techniques; Itraconazole; Ketoconazole; Malaysia; Microbial Sensitivity Tests; Naphthalenes; Sporothrix; Sporotrichosis; Terbinafine; Triazoles | 2017 |
Characterization of 1-Aminobenzotriazole and Ketoconazole as Novel Inhibitors of Monoamine Oxidase (MAO): An In Vitro Investigation.
Topics: Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; Isoenzymes; Ketoconazole; Kinetics; Liver; Mice; Microsomes, Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Triazoles | 2017 |
Minimal inhibitory concentration distributions and epidemiological cutoff values of five antifungal agents against Sporothrix brasiliensis.
Topics: Amphotericin B; Animals; Antifungal Agents; Cats; Drug Resistance, Fungal; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Naphthalenes; Sporothrix; Terbinafine; Triazoles | 2017 |
Identification of endocrine disrupting chemicals acting on human aromatase.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Benzhydryl Compounds; Biological Assay; Endocrine Disruptors; Enzyme-Linked Immunosorbent Assay; Estrone; Gene Expression; Humans; Ketoconazole; Ligands; NADP; Nicotine; Nitriles; Phenols; Protein Binding; Recombinant Proteins; Resveratrol; Sildenafil Citrate; Small Molecule Libraries; Stilbenes; Triazoles | 2018 |
Evaluation of selected Indian medicinal plants for antagonistic potential against Malassezia spp. and the synergistic effect of embelin in combination with ketoconazole.
Topics: Antifungal Agents; Benzoquinones; Drug Combinations; Drug Synergism; Embelia; Humans; India; Ketoconazole; Lipase; Malassezia; Microbial Sensitivity Tests; Plant Extracts; Plants, Medicinal; Triazoles | 2017 |
Comparison of particle size methodology and assessment of nanoparticle tracking analysis (NTA) as a tool for live monitoring of crystallisation pathways.
Topics: Antifungal Agents; Chemistry, Pharmaceutical; Crystallization; Dynamic Light Scattering; Excipients; Itraconazole; Ketoconazole; Nanoparticles; Particle Size; Polyethylene Glycols; Solvents; Technology, Pharmaceutical; Triazoles | 2018 |
Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Energy Metabolism; Gene Expression Regulation, Neoplastic; Glioblastoma; Hexokinase; Humans; Ketoconazole; Male; Mice; Triazoles; Xenograft Model Antitumor Assays | 2019 |
Inhibitory effect of isavuconazole, ketoconazole, and voriconazole on the pharmacokinetics of methadone in vivo and in vitro.
Topics: Analgesics, Opioid; Animals; Antifungal Agents; Ketoconazole; Male; Methadone; Nitriles; Pyridines; Rats, Sprague-Dawley; Triazoles; Voriconazole | 2019 |
Doravirine and the Potential for CYP3A-Mediated Drug-Drug Interactions.
Topics: Adolescent; Adult; Aged; Alkynes; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Ketoconazole; Male; Middle Aged; Pyridones; Ritonavir; Triazoles; Young Adult | 2019 |
Comparison of the inhibitory effect of ketoconazole, voriconazole, fluconazole, and itraconazole on the pharmacokinetics of bosentan and its corresponding active metabolite hydroxy bosentan in rats.
Topics: Animals; Antifungal Agents; Antihypertensive Agents; Bosentan; Drug Interactions; Fluconazole; Itraconazole; Ketoconazole; Male; Rats; Rats, Sprague-Dawley; Triazoles; Voriconazole | 2020 |
Identification and Antifungal Activity Profile of Candida Species Isolated from Patients with Pemphigus Vulgaris with Oral Lesions.
Topics: Adult; Amphotericin B; Antifungal Agents; Candida; Candidiasis, Oral; Disk Diffusion Antimicrobial Tests; Econazole; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Pemphigus; Triazoles | 2019 |
In vitro antifungal activity of luliconazole against nondermatophytic moulds.
Topics: Amphotericin B; Antifungal Agents; Clotrimazole; Fluconazole; Fungi; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Morpholines; Sequence Analysis, DNA; Terbinafine; Triazoles; Voriconazole | 2020 |
Novel Application of Pentabromobenzyl Column for Simultaneous Determination of Eight Antifungal Drugs Using High-performance Liquid Chromatography.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Clotrimazole; Humans; Hydrocarbons, Brominated; Imidazoles; Ketoconazole; Liquid-Liquid Extraction; Molecular Structure; Thiophenes; Triazoles; Voriconazole | 2020 |
Comparison of in vitro antifungal activity of novel triazoles with available antifungal agents against dermatophyte species caused tinea pedis.
Topics: Antifungal Agents; Arthrodermataceae; Dermatomycoses; Fluconazole; Griseofulvin; Humans; Imidazoles; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Terbinafine; Tinea; Tinea Pedis; Triazoles; Trichophyton; Voriconazole | 2020 |
Differential Impacts of Azole Antifungal Drugs on the Pharmacokinetic Profiles of Dasatinib in Rats by LC-MS-MS.
Topics: Administration, Oral; Animals; Antifungal Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dasatinib; Drug Interactions; Drug Monitoring; Humans; Itraconazole; Ketoconazole; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Models, Animal; Protein Kinase Inhibitors; Rats; Tandem Mass Spectrometry; Triazoles; Voriconazole | 2020 |
Leveraging Physiologically Based Pharmacokinetic Modeling and Experimental Data to Guide Dosing Modification of CYP3A-Mediated Drug-Drug Interactions in the Pediatric Population.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Antifungal Agents; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Infant; Ketoconazole; Macrolides; Midazolam; Tandem Mass Spectrometry; Triazoles | 2021 |
In Vitro-In Vivo Correlation in Cocrystal Dissolution: Consideration of Drug Release Profiles Based on Coformer Dissolution and Absorption Behavior.
Topics: 4-Aminobenzoic Acid; Adjuvants, Pharmaceutic; Administration, Oral; Animals; Chemistry, Pharmaceutical; Crystallization; Drug Compounding; Drug Liberation; Gastrointestinal Absorption; Itraconazole; Ketoconazole; Male; Rats; Solubility; Triazoles | 2021 |
Permeabilized Cryopreserved Human Hepatocytes as an Exogenous Metabolic System in a Novel Metabolism-Dependent Cytotoxicity Assay for the Evaluation of Metabolic Activation and Detoxification of Drugs Associated with Drug-Induced Liver Injuries: Results w
Topics: Acetaminophen; Activation, Metabolic; Amiodarone; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Cytochrome P-450 Enzyme System; Glutathione; HEK293 Cells; Hepatocytes; Humans; Ketoconazole; Piperazines; Triazoles; Troglitazone | 2022 |
Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series.
Topics: Animals; Anti-Inflammatory Agents; Antifungal Agents; Dermatitis; Dog Diseases; Dogs; Ear Canal; Exudates and Transudates; Hypersensitivity; Immunoglobulin E; Intradermal Tests; Ketoconazole; Malassezia; Mometasone Furoate; Neutrophils; Otitis; Otitis Media, Suppurative; Prednisolone; Treatment Outcome; Triazoles | 2021 |