ketoconazole and tretinoin

ketoconazole has been researched along with tretinoin in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (10.20)	18.7374
1990's	17 (34.69)	18.2507
2000's	14 (28.57)	29.6817
2010's	13 (26.53)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Brodie, AM; Clement, OO; Gediya, LK; Goloubeva, OG; Handratta, VD; Huynh, CK; Nanne, IP; Njar, VC; Patel, JB; Soprano, DR	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Aström, A; Chambon, P; Duell, EA; Griffiths, CE; Voorhees, JJ	1
Boerman, MH; Burns, RD; Napoli, JL; Posch, KC	1
Coene, MC; Cools, W; Goossens, J; Monbaliu, J; Van Wauwe, JP	1
Janssen, PA; Vanden Bossche, H; Willemsens, G	1
Coene, MC; Cools, W; Goossens, J; Lauwers, W; Van Nijen, G; Van Wauwe, JP	1
Hay, RJ	1
Napoli, JL; Williams, JB	1
Napoli, JL	1
Calayag, M; Fossella, FV; Hong, WK; Krakoff, IH; Lee, JS; Lippman, SM; Newman, RA; Raber, MN	1
Muindi, JR; Warrell, RP; Young, CW	2
Adamson, PC	1
Buzney, SM; Dowgiert, RK; Doyle, JW	1
Fiorella, PD; Napoli, JL	1
DeGrazia, F; Francis, PA; Huselton, C; Kris, MG; Muindi, JR; Orazem, JP; Rigas, JR; Warrell, RP; Young, CW	1
Bruynseels, J; De Coster, R; Wouters, W	1
Duell, EA; Kang, S; Li, XY; Voorhees, JJ	1
Randolph, RK; Simon, M	1
Dräger, UC; McCaffery, P; Yamamoto, M	1
Byun, Y; Carey, TE; Choi, JH; Chung, JW; Han, IS; Kim, SH; Kim, SY; Lee, HR; Lee, KS; Yu, HK	1
Maden, M; Sonneveld, E; van den Brink, CE; van der Leede, BJ; van der Saag, PT	1
Chithalen, JV; Jones, G; Luu, L; Petkovich, M	1
Ahmadi, M; Le Baut, G; Le Borgne, M; Marchand, P; Nicholls, PJ; Smith, HJ	1
Araico, A; Cárcel-Trullols, J; Peris, JE; Saadeddin, A; Torres-Molina, F	1
Angotti, M; Hartmann, RW; Kirby, AJ; Nicholls, PJ; Sewell, RD; Simons, C; Smith, HJ	1
Arzt, E; Castillo, V; Giacomini, D; Grossman, AB; Holsboer, F; Labeur, M; Páez-Pereda, M; Stalla, GK; Stalla, J; Theodoropoulou, M	1
Jacobson, EL; Jacobson, MK; Kim, H; Tashtoush, BM	1
el-Metwally, TH; Hameed, DA	1
Lotan, R; Lotan, Y	1
Avram, MR; Rogers, NE	1
Maares, J; Meyer, I; Roos, B; Sauer, J; Schmitt-Hoffmann, AH; Schoetzau, A; Spickermann, J	1
Buttrick, B; Goodlett, DR; Isoherranen, N; Nelson, WL; Shaffer, SA; Shimshoni, JA; Thatcher, JE	1
Barahona Constanzo, MJ; del Pozo Picó, C	1
Blackburn, J; Blom, A; Ishizawa, M; Lancaster, ST; Makishima, M; Mansell, JP	1

Reviews

6 review(s) available for ketoconazole and tretinoin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Pharmacokinetics of all-trans-retinoic acid: clinical implications in acute promyelocytic leukemia. Seminars in hematology, 1994, Volume: 31, Issue:4 Suppl 5 Topics: Animals; Clinical Trials as Topic; Drug Administration Schedule; Humans; Ketoconazole; Leukemia, Promyelocytic, Acute; Macaca mulatta; Time Factors; Tretinoin	1994
Clinical pharmacology of all-trans retinoic acid. Leukemia, 1994, Volume: 8, Issue:11 Topics: Carcinoma, Non-Small-Cell Lung; Humans; Ketoconazole; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Male; Metabolic Clearance Rate; Multiple Myeloma; Oxidation-Reduction; Prostatic Neoplasms; Tretinoin	1994
P450-dependent enzymes as targets for prostate cancer therapy. The Journal of steroid biochemistry and molecular biology, 1996, Volume: 56, Issue:1-6 Spec N Topics: Adenocarcinoma; Aldehyde-Lyases; Androgen Antagonists; Androgens; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Cattle; Clinical Trials as Topic; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Imidazoles; Ketoconazole; Male; Mice; Neoplasm Proteins; Prostatic Neoplasms; Rats; Rats, Wistar; Salvage Therapy; Steroid 17-alpha-Hydroxylase; Tretinoin; Tumor Cells, Cultured	1996
Medical treatments for male and female pattern hair loss. Journal of the American Academy of Dermatology, 2008, Volume: 59, Issue:4 Topics: Adult; Alopecia; Androgen Antagonists; Azasteroids; Drug Therapy, Combination; Dutasteride; Female; Finasteride; Hair; Humans; Hyperhidrosis; Ketoconazole; Male; Minoxidil; Phototherapy; Prostate; Sperm Count; Tretinoin	2008
New prospects for drug treatment in Cushing disease. Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:10 Topics: Adenoma; Adrenocorticotropic Hormone; Animals; Cabergoline; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Drug Evaluation, Preclinical; Ergolines; Etomidate; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Metyrapone; Mice; Mifepristone; Mitotane; Multicenter Studies as Topic; Pituitary ACTH Hypersecretion; Pituitary Neoplasms; PPAR gamma; Pyridines; Rats; Somatostatin; Therapies, Investigational; Tretinoin	2012

Trials

5 trial(s) available for ketoconazole and tretinoin

Article	Year
Phase I evaluation of all-trans retinoic acid with and without ketoconazole in adults with solid tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:6 Topics: Adult; Aged; Female; Humans; Ketoconazole; Male; Middle Aged; Neoplasms; Tretinoin	1995
Clinical pharmacology of all-trans retinoic acid. Leukemia, 1994, Volume: 8 Suppl 3 Topics: Antineoplastic Agents; Drug Administration Schedule; Half-Life; Humans; Ketoconazole; Neoplasms; Stereoisomerism; Tretinoin	1994
Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid, and its modulation by ketoconazole. Journal of the National Cancer Institute, 1993, Dec-01, Volume: 85, Issue:23 Topics: Carcinoma, Non-Small-Cell Lung; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Humans; Ketoconazole; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Neoplasms; Tretinoin	1993
Retinoic acid as a novel medical therapy for Cushing's disease in dogs. Endocrinology, 2006, Volume: 147, Issue:9 Topics: Adenoma; Adrenocorticotropic Hormone; alpha-MSH; Animals; Body Weight; Creatinine; Dog Diseases; Dogs; Female; Hydrocortisone; Ketoconazole; Magnetic Resonance Imaging; Male; Pituitary ACTH Hypersecretion; Pituitary Gland; Pituitary Neoplasms; Survival Rate; Tretinoin	2006
Pharmacokinetic interactions between alitretinoin and ketoconazole or simvastatin or ciclosporin A. Clinical and experimental dermatology, 2011, Volume: 36 Suppl 2 Topics: Adolescent; Adult; Alitretinoin; Antifungal Agents; Cross-Over Studies; Cyclosporine; Dermatologic Agents; Drug Administration Schedule; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Ketoconazole; Male; Middle Aged; Simvastatin; Tretinoin; Young Adult	2011

Other Studies

38 other study(ies) available for ketoconazole and tretinoin

Article	Year
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice. Journal of medicinal chemistry, 2004, Dec-30, Volume: 47, Issue:27 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cricetinae; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Male; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Microsomes, Liver; Neoplasm Transplantation; Prostatic Neoplasms; Retinoic Acid 4-Hydroxylase; Stereoisomerism; Transplantation, Heterologous; Tretinoin	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature chemical biology, 2006, Volume: 2, Issue:6 Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship	2006
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2. Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24 Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Overcoming drug resistance: studies presented at ASCO. Oncology (Williston Park, N.Y.), 1992, Volume: 6, Issue:12 Topics: Antigens, CD; Antigens, CD34; Cyclosporine; Drug Resistance; Humans; Ketoconazole; Leukemia; Tretinoin	1992
Human skin levels of retinoic acid and cytochrome P-450-derived 4-hydroxyretinoic acid after topical application of retinoic acid in vivo compared to concentrations required to stimulate retinoic acid receptor-mediated transcription in vitro. The Journal of clinical investigation, 1992, Volume: 90, Issue:4 Topics: Administration, Topical; Adult; Carrier Proteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Ketoconazole; Receptors, Retinoic Acid; Skin; Transcription, Genetic; Tretinoin	1992
Holocellular retinol binding protein as a substrate for microsomal retinal synthesis. Biochemistry, 1991, Jun-25, Volume: 30, Issue:25 Topics: Animals; Ethanol; Ketoconazole; Kinetics; Male; Microsomes; Microsomes, Liver; NADP; Organ Specificity; Rats; Rats, Inbred Strains; Retinaldehyde; Retinol-Binding Proteins; Retinol-Binding Proteins, Cellular; Tretinoin	1991
Effects of cytochrome P-450 inhibitors on the in vivo metabolism of all-trans-retinoic acid in rats. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1 Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Imidazoles; Ketoconazole; Male; Rats; Rats, Inbred Strains; Tretinoin	1990
Cytochrome-P-450-dependent metabolism of retinoic acid in rat skin microsomes: inhibition by ketoconazole. Skin pharmacology : the official journal of the Skin Pharmacology Society, 1988, Volume: 1, Issue:3 Topics: Animals; Animals, Newborn; Antimetabolites; Biotransformation; Carbon Monoxide; Cricetinae; Cytochrome P-450 Enzyme System; In Vitro Techniques; Itraconazole; Ketoconazole; Mesocricetus; Miconazole; Microsomes; Microsomes, Liver; Oxygen; Rats; Rats, Inbred Strains; Skin; Tretinoin	1988
Ketoconazole inhibits the in vitro and in vivo metabolism of all-trans-retinoic acid. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2 Topics: Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cricetinae; Female; Gas Chromatography-Mass Spectrometry; Ketoconazole; Kinetics; Liver; Male; Mesocricetus; Microsomes, Liver; Rats; Rats, Inbred Strains; Tretinoin	1988
The current status of antimycotics in the treatment of local mycoses. Acta dermato-venereologica. Supplementum, 1986, Volume: 121 Topics: Administration, Oral; Administration, Topical; Amphotericin B; Antifungal Agents; Benzoates; Dermatomycoses; Drug Combinations; Etretinate; Female; Griseofulvin; Humans; Imidazoles; Ketoconazole; Nystatin; Potassium Permanganate; Resorcinols; Salicylates; Salicylic Acid; Suppositories; Tretinoin; Vagina	1986
Inhibition of retinoic acid metabolism by imidazole antimycotics in F9 embryonal carcinoma cells. Biochemical pharmacology, 1987, Apr-15, Volume: 36, Issue:8 Topics: Cell Line; Clotrimazole; Embryonal Carcinoma Stem Cells; Imidazoles; Ketoconazole; Metyrapone; Miconazole; Neoplastic Stem Cells; Tretinoin	1987
Retinol metabolism in LLC-PK1 Cells. Characterization of retinoic acid synthesis by an established mammalian cell line. The Journal of biological chemistry, 1986, Oct-15, Volume: 261, Issue:29 Topics: Animals; Cell Line; Disulfiram; Half-Life; Ketoconazole; Kidney; Kinetics; Swine; Tretinoin; Vitamin A	1986
Retinoic acid metabolism in cultured retinal pigment epithelial cells. Investigative ophthalmology & visual science, 1995, Volume: 36, Issue:3 Topics: Animals; Cattle; Cell Division; Cells, Cultured; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Ketoconazole; Oxygenases; Pigment Epithelium of Eye; Subcellular Fractions; Tretinoin	1995
Microsomal retinoic acid metabolism. Effects of cellular retinoic acid-binding protein (type I) and C18-hydroxylation as an initial step. The Journal of biological chemistry, 1994, Apr-08, Volume: 269, Issue:14 Topics: Animals; Hydroxylation; Ketoconazole; Kidney; Liver; Lung; Male; Microsomes; Rats; Receptors, Retinoic Acid; Testis; Tretinoin	1994
The retinoid X receptor agonist 9-cis-retinoic acid and the 24-hydroxylase inhibitor ketoconazole increase activity of 1,25-dihydroxyvitamin D3 in human skin in vivo. The Journal of investigative dermatology, 1997, Volume: 108, Issue:4 Topics: Adult; Alitretinoin; Calcitriol; Cytochrome P-450 Enzyme System; Drug Synergism; Gene Expression; Humans; Ketoconazole; Receptors, Retinoic Acid; Retinoid X Receptors; Skin; Steroid Hydroxylases; Transcription Factors; Transcription, Genetic; Tretinoin; Vitamin D3 24-Hydroxylase	1997
Metabolism of all-trans-retinoic acid by cultured human epidermal keratinocytes. Journal of lipid research, 1997, Volume: 38, Issue:7 Topics: Albumins; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Epidermis; Esters; Homeostasis; Humans; Keratinocytes; Ketoconazole; Kinetics; Tretinoin	1997
A novel assay for retinoic acid catabolic enzymes shows high expression in the developing hindbrain. Brain research. Developmental brain research, 1998, Apr-17, Volume: 107, Issue:1 Topics: Aging; Animals; Animals, Newborn; Embryo, Mammalian; Embryonic and Fetal Development; Enzymes; Ketoconazole; Methods; Mice; NADP; Receptors, Retinoic Acid; Recombinant Proteins; Rhombencephalon; Tretinoin	1998
The induction of P450-mediated oxidation of all-trans retinoic acid by retinoids in head and neck squamous cell carcinoma cell lines. Metabolism: clinical and experimental, 1998, Volume: 47, Issue:8 Topics: Antibiotics, Antineoplastic; Antifungal Agents; Antineoplastic Agents; Carcinoma, Squamous Cell; Cycloheximide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Head and Neck Neoplasms; Humans; Ketoconazole; Oxidation-Reduction; Protein Synthesis Inhibitors; Retinoids; Tretinoin; Tumor Cells, Cultured	1998
Embryonal carcinoma cell lines stably transfected with mRARbeta2-lacZ: sensitive system for measuring levels of active retinoids. Experimental cell research, 1999, Aug-01, Volume: 250, Issue:2 Topics: Animals; Carcinoma, Embryonal; Chick Embryo; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gene Expression Regulation, Developmental; Genes, Reporter; Imidazoles; Isomerism; Ketoconazole; Limb Buds; Mesoderm; Mice; Promoter Regions, Genetic; Receptors, Retinoic Acid; Retinoids; Time Factors; Transcriptional Activation; Transfection; Tretinoin; Tumor Cells, Cultured	1999
HPLC-MS/MS analysis of the products generated from all-trans-retinoic acid using recombinant human CYP26A. Journal of lipid research, 2002, Volume: 43, Issue:7 Topics: Animals; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cytochrome P-450 Enzyme System; HeLa Cells; Humans; Ketoconazole; Mass Spectrometry; Recombinant Proteins; Retinoic Acid 4-Hydroxylase; RNA, Messenger; Tretinoin	2002
Retinoic acid metabolism inhibition by 3-azolylmethyl-1H-indoles and 2, 3 or 5-(alpha-azolylbenzyl)-1H-indoles. Journal of enzyme inhibition and medicinal chemistry, 2003, Volume: 18, Issue:2 Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Hydroxylation; In Vitro Techniques; Indoles; Ketoconazole; Microsomes, Liver; Molecular Structure; Rats; Structure-Activity Relationship; Tretinoin; Triazoles	2003
Effect of cytochrome P450 inhibitors (diethyl dithiocarbamate, ketoconazole and grapefruit juice) on the pharmacokinetics of all-trans-retinoic acid. Farmaco (Societa chimica italiana : 1989), 2004, Volume: 59, Issue:9 Topics: Animals; Beverages; Citrus paradisi; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Enzyme Inhibitors; Ketoconazole; Rats; Tretinoin	2004
Effect of 2-(4-aminophenylmethyl)-6-hydroxy-3, 4-dihydronaphthalen-1(2H)-one on all-trans and 13-cis-retinoic acid levels in plasma quantified by high perfomance liquid chromatography coupled to tandem mass spectrometry. Journal of enzyme inhibition and medicinal chemistry, 2005, Volume: 20, Issue:3 Topics: Animals; Chromatography, High Pressure Liquid; Isotretinoin; Ketoconazole; Male; Mass Spectrometry; Naphthalenes; Rats; Rats, Inbred WF; Spectrometry, Mass, Electrospray Ionization; Tetralones; Tretinoin	2005
Formulation compatibility of myristyl nicotinate with drugs used to treat dermatological conditions involving an impaired skin barrier. Drug development and industrial pharmacy, 2007, Volume: 33, Issue:11 Topics: Chemistry, Pharmaceutical; Dermatologic Agents; Humans; Hydrocortisone; Ketoconazole; Metronidazole; Niacin; Skin; Skin Diseases; Tretinoin; Triamcinolone Acetonide	2007
The effectiveness of retinoic acid treatment in bladder cancer: impact on recurrence, survival and TGFalpha and VEGF as end-point biomarkers. Cancer biology & therapy, 2008, Volume: 7, Issue:1 Topics: Aged; Biomarkers; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Humans; Ketoconazole; Middle Aged; Neoplasm Recurrence, Local; Transforming Growth Factor alpha; Tretinoin; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A	2008
Prevention of bladder cancer recurrence by retinoic acid-ketoconazole: a promising strategy? Cancer biology & therapy, 2008, Volume: 7, Issue:1 Topics: Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Drug Therapy, Combination; Humans; Ketoconazole; Neoplasm Recurrence, Local; Tretinoin; Urinary Bladder Neoplasms	2008
Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase. Molecular pharmacology, 2011, Volume: 80, Issue:2 Topics: Animals; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Ketoconazole; Ligands; Liver; Mixed Function Oxygenases; Protease Inhibitors; Rats; Retinoic Acid 4-Hydroxylase; Substrate Specificity; Tretinoin	2011
24,25-Dihydroxyvitamin D3 cooperates with a stable, fluoromethylene LPA receptor agonist to secure human (MG63) osteoblast maturation. Steroids, 2014, Volume: 83 Topics: 24,25-Dihydroxyvitamin D 3; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Calcitriol; Cell Differentiation; Fluorescent Dyes; Humans; Ketoconazole; Mitogens; Organophosphonates; Osteoblasts; Osteocalcin; Receptors, Calcitriol; Receptors, Lysophosphatidic Acid; Stereoisomerism; Transcription, Genetic; Tretinoin	2014