ketoconazole and thiophenes

ketoconazole has been researched along with thiophenes in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Agut, J; Casas, E; Ortiz, JA; Palacín, C; Sacristán, A; Salgado, J1
Carrillo-Muñoz, AJ; Casals, J; del Valle, O; Guardià, C; Guglietta, A; Palacín, C; Quindós, G; Rodríguez, V1
Eckstein, JA; Farid, NA; Heim, JB; Kasper, SC; Kurihara, A; Rehmel, JL; Ring, BJ; Wrighton, SA1
Brandt, JT; Darstein, C; Ernest, CS; Farid, NA; Jakubowski, JA; Payne, CD; Salazar, DE; Small, DS; Winters, KJ1
Balci, DD; Cetin, M1
Becka, M; Kubitza, D; Mueck, W1
Abou El-Alamin, MM; Aboul-Enein, HY; Atia, MA; Sultan, MA1

Trials

2 trial(s) available for ketoconazole and thiophenes

ArticleYear
Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently.
    Clinical pharmacology and therapeutics, 2007, Volume: 81, Issue:5

    Topics: Adult; Area Under Curve; Clopidogrel; Cross-Over Studies; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Female; Humans; Ketoconazole; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine

2007
Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects.
    British journal of clinical pharmacology, 2013, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Anticoagulants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Erythromycin; Humans; Ketoconazole; Metabolic Clearance Rate; Midazolam; Middle Aged; Morpholines; Rivaroxaban; Substrate Specificity; Thiophenes; Young Adult

2013

Other Studies

5 other study(ies) available for ketoconazole and thiophenes

ArticleYear
Direct membrane-damaging effect of sertaconazole on Candida albicans as a mechanism of its fungicidal activity.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:5A

    Topics: Adenosine Triphosphate; Antifungal Agents; Candida albicans; Cell Membrane; Cell Membrane Permeability; Imidazoles; Ketoconazole; Miconazole; Spectrophotometry, Ultraviolet; Thiophenes

1992
In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis.
    Chemotherapy, 2004, Volume: 50, Issue:6

    Topics: Antifungal Agents; Arthrodermataceae; Ascomycota; Clotrimazole; Econazole; Fluconazole; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Naphthalenes; Terbinafine; Thiophenes

2004
Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:4

    Topics: Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; Ketoconazole; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Recombinant Proteins; Thiophenes

2006
Widespread, chronic, and fluconazole-resistant Trichophyton rubrum infection in an immunocompetent patient.
    Mycoses, 2008, Volume: 51, Issue:6

    Topics: Animals; Antifungal Agents; Drug Resistance, Fungal; Female; Fluconazole; Humans; Imidazoles; Itraconazole; Ketoconazole; Middle Aged; Thiophenes; Tinea; Trichophyton

2008
Novel Application of Pentabromobenzyl Column for Simultaneous Determination of Eight Antifungal Drugs Using High-performance Liquid Chromatography.
    Combinatorial chemistry & high throughput screening, 2020, Volume: 23, Issue:10

    Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Clotrimazole; Humans; Hydrocarbons, Brominated; Imidazoles; Ketoconazole; Liquid-Liquid Extraction; Molecular Structure; Thiophenes; Triazoles; Voriconazole

2020